| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is gabD [C]
Identifier: 41408284
GI number: 41408284
Start: 2428054
End: 2428482
Strand: Reverse
Name: gabD [C]
Synonym: MAP2186c
Alternate gene names: 41408284
Gene position: 2428482-2428054 (Counterclockwise)
Preceding gene: 41408285
Following gene: 41408283
Centisome position: 50.28
GC content: 66.67
Gene sequence:
>429_bases GTGAAGTTGGCCGAAGAACACGGCGGCAAGGTGTTCTGCGGTGGCGGACGCCCGGCGGGTCTTGACCGCGGCTACTACTT CGAACCGACCGTGCTCGACCTGCCCAGCAACGCGAATCCGGCTGCGCAGGAGGAGATCTTCGGCCCGATCATCGGCGTGC TGGGCTACCGCGATATCGACGACGCGGTCGCCATCGCCAACGACAGCATCTACGGCCTGTCCGGGCAGGTGTACGGGACC GACGCGGCGGCCGCGCTGCAGGTCGCGCGCCGACTGCGCACCGGCGCCGTCAACGTCAACACCACCGTCTTCTCCGCCTA CGCGCCGAGCGGCGGATACAAGCAAAGCGGTCTGGGCCGCGAACGGGGTCCGGACGGCATTCGCGAGTTCCAGGAGGTCA AGCACATGTCGATTGGGGAGTTGAAATGA
Upstream 100 bases:
>100_bases CGCGATGTACCAGCAGATCAAGGTCGGGCCGCCCAGCGACGAAACGGCGATGATGGGCCCGGTCATCAGCGCGGCCTAGC GCGACAAATGCGAGCAGTAC
Downstream 100 bases:
>100_bases GCTCAGAAACCAACGGAGATAAGACATACAACCTGGACTGGCTGATCTCGGTCGACGACCACATCCTCGAGCCGCCAAAC CTGTGGGTCGACCGGGTCGC
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 142; Mature: 142
Protein sequence:
>142_residues MKLAEEHGGKVFCGGGRPAGLDRGYYFEPTVLDLPSNANPAAQEEIFGPIIGVLGYRDIDDAVAIANDSIYGLSGQVYGT DAAAALQVARRLRTGAVNVNTTVFSAYAPSGGYKQSGLGRERGPDGIREFQEVKHMSIGELK
Sequences:
>Translated_142_residues MKLAEEHGGKVFCGGGRPAGLDRGYYFEPTVLDLPSNANPAAQEEIFGPIIGVLGYRDIDDAVAIANDSIYGLSGQVYGT DAAAALQVARRLRTGAVNVNTTVFSAYAPSGGYKQSGLGRERGPDGIREFQEVKHMSIGELK >Mature_142_residues MKLAEEHGGKVFCGGGRPAGLDRGYYFEPTVLDLPSNANPAAQEEIFGPIIGVLGYRDIDDAVAIANDSIYGLSGQVYGT DAAAALQVARRLRTGAVNVNTTVFSAYAPSGGYKQSGLGRERGPDGIREFQEVKHMSIGELK
Specific function: 4-aminobutyrate (GABA) degradation. [C]
COG id: COG1012
COG function: function code C; NAD-dependent aldehyde dehydrogenases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldehyde dehydrogenase family [H]
Homologues:
Organism=Homo sapiens, GI25777732, Length=135, Percent_Identity=41.4814814814815, Blast_Score=104, Evalue=3e-23, Organism=Homo sapiens, GI21361176, Length=135, Percent_Identity=40, Blast_Score=101, Evalue=2e-22, Organism=Homo sapiens, GI25777730, Length=139, Percent_Identity=36.6906474820144, Blast_Score=99, Evalue=1e-21, Organism=Homo sapiens, GI25777726, Length=134, Percent_Identity=38.8059701492537, Blast_Score=94, Evalue=3e-20, Organism=Homo sapiens, GI25777724, Length=134, Percent_Identity=38.8059701492537, Blast_Score=94, Evalue=3e-20, Organism=Homo sapiens, GI25777728, Length=134, Percent_Identity=38.8059701492537, Blast_Score=94, Evalue=4e-20, Organism=Homo sapiens, GI153266822, Length=135, Percent_Identity=37.037037037037, Blast_Score=91, Evalue=2e-19, Organism=Homo sapiens, GI115387104, Length=143, Percent_Identity=34.2657342657343, Blast_Score=86, Evalue=1e-17, Organism=Homo sapiens, GI12007648, Length=144, Percent_Identity=31.25, Blast_Score=77, Evalue=7e-15, Organism=Homo sapiens, GI301500698, Length=144, Percent_Identity=31.25, Blast_Score=77, Evalue=7e-15, Organism=Homo sapiens, GI25952152, Length=144, Percent_Identity=31.25, Blast_Score=76, Evalue=9e-15, Organism=Homo sapiens, GI21614513, Length=139, Percent_Identity=34.5323741007194, Blast_Score=75, Evalue=2e-14, Organism=Homo sapiens, GI238814322, Length=118, Percent_Identity=34.7457627118644, Blast_Score=72, Evalue=2e-13, Organism=Homo sapiens, GI25777721, Length=117, Percent_Identity=41.025641025641, Blast_Score=69, Evalue=1e-12, Organism=Homo sapiens, GI4507229, Length=117, Percent_Identity=41.025641025641, Blast_Score=69, Evalue=1e-12, Organism=Escherichia coli, GI1789015, Length=138, Percent_Identity=41.304347826087, Blast_Score=96, Evalue=1e-21, Organism=Escherichia coli, GI87081896, Length=136, Percent_Identity=36.0294117647059, Blast_Score=89, Evalue=9e-20, Organism=Escherichia coli, GI1786504, Length=137, Percent_Identity=36.4963503649635, Blast_Score=88, Evalue=2e-19, Organism=Escherichia coli, GI87082295, Length=142, Percent_Identity=34.5070422535211, Blast_Score=86, Evalue=1e-18, Organism=Escherichia coli, GI87081926, Length=129, Percent_Identity=37.984496124031, Blast_Score=81, Evalue=3e-17, Organism=Escherichia coli, GI1787715, Length=130, Percent_Identity=34.6153846153846, Blast_Score=79, Evalue=1e-16, Organism=Escherichia coli, GI1787558, Length=126, Percent_Identity=38.8888888888889, Blast_Score=76, Evalue=7e-16, Organism=Escherichia coli, GI1787684, Length=132, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562198, Length=135, Percent_Identity=40, Blast_Score=99, Evalue=6e-22, Organism=Caenorhabditis elegans, GI32564736, Length=135, Percent_Identity=38.5185185185185, Blast_Score=97, Evalue=2e-21, Organism=Caenorhabditis elegans, GI25144435, Length=135, Percent_Identity=38.5185185185185, Blast_Score=97, Evalue=3e-21, Organism=Caenorhabditis elegans, GI133930964, Length=135, Percent_Identity=41.4814814814815, Blast_Score=89, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17534119, Length=125, Percent_Identity=43.2, Blast_Score=85, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71995606, Length=138, Percent_Identity=36.231884057971, Blast_Score=83, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17551164, Length=141, Percent_Identity=32.6241134751773, Blast_Score=80, Evalue=3e-16, Organism=Caenorhabditis elegans, GI25143874, Length=130, Percent_Identity=33.8461538461538, Blast_Score=76, Evalue=6e-15, Organism=Caenorhabditis elegans, GI25143876, Length=134, Percent_Identity=32.8358208955224, Blast_Score=75, Evalue=8e-15, Organism=Saccharomyces cerevisiae, GI6320917, Length=138, Percent_Identity=34.0579710144928, Blast_Score=91, Evalue=5e-20, Organism=Saccharomyces cerevisiae, GI6323821, Length=123, Percent_Identity=36.5853658536585, Blast_Score=87, Evalue=9e-19, Organism=Saccharomyces cerevisiae, GI6324950, Length=135, Percent_Identity=34.0740740740741, Blast_Score=86, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6323822, Length=123, Percent_Identity=36.5853658536585, Blast_Score=85, Evalue=4e-18, Organism=Saccharomyces cerevisiae, GI6325196, Length=139, Percent_Identity=33.8129496402878, Blast_Score=84, Evalue=6e-18, Organism=Saccharomyces cerevisiae, GI6319478, Length=139, Percent_Identity=35.2517985611511, Blast_Score=82, Evalue=4e-17, Organism=Saccharomyces cerevisiae, GI6321828, Length=131, Percent_Identity=34.3511450381679, Blast_Score=76, Evalue=2e-15, Organism=Drosophila melanogaster, GI20129399, Length=139, Percent_Identity=39.568345323741, Blast_Score=97, Evalue=5e-21, Organism=Drosophila melanogaster, GI281362580, Length=133, Percent_Identity=39.0977443609023, Blast_Score=92, Evalue=9e-20, Organism=Drosophila melanogaster, GI62472918, Length=133, Percent_Identity=39.0977443609023, Blast_Score=92, Evalue=9e-20, Organism=Drosophila melanogaster, GI62472926, Length=133, Percent_Identity=39.0977443609023, Blast_Score=92, Evalue=9e-20, Organism=Drosophila melanogaster, GI62472936, Length=133, Percent_Identity=39.0977443609023, Blast_Score=92, Evalue=9e-20, Organism=Drosophila melanogaster, GI21356737, Length=133, Percent_Identity=39.0977443609023, Blast_Score=92, Evalue=9e-20, Organism=Drosophila melanogaster, GI24650465, Length=140, Percent_Identity=35, Blast_Score=82, Evalue=8e-17, Organism=Drosophila melanogaster, GI24585660, Length=136, Percent_Identity=36.7647058823529, Blast_Score=81, Evalue=2e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016161 - InterPro: IPR016163 - InterPro: IPR016160 - InterPro: IPR016162 - InterPro: IPR015590 [H]
Pfam domain/function: PF00171 Aldedh [H]
EC number: =1.2.1.3 [H]
Molecular weight: Translated: 15035; Mature: 15035
Theoretical pI: Translated: 5.19; Mature: 5.19
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLAEEHGGKVFCGGGRPAGLDRGYYFEPTVLDLPSNANPAAQEEIFGPIIGVLGYRDID CCCCCCCCCEEEECCCCCCCCCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC DAVAIANDSIYGLSGQVYGTDAAAALQVARRLRTGAVNVNTTVFSAYAPSGGYKQSGLGR CCEEECCCCEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCC ERGPDGIREFQEVKHMSIGELK CCCCHHHHHHHHHHCCCCCCCC >Mature Secondary Structure MKLAEEHGGKVFCGGGRPAGLDRGYYFEPTVLDLPSNANPAAQEEIFGPIIGVLGYRDID CCCCCCCCCEEEECCCCCCCCCCCEEECCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC DAVAIANDSIYGLSGQVYGTDAAAALQVARRLRTGAVNVNTTVFSAYAPSGGYKQSGLGR CCEEECCCCEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCC ERGPDGIREFQEVKHMSIGELK CCCCHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA