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The map label for this gene is malY [C]

Identifier: 41408153

GI number: 41408153

Start: 2263776

End: 2264981

Strand: Direct

Name: malY [C]

Synonym: MAP2055

Alternate gene names: 41408153

Gene position: 2263776-2264981 (Clockwise)

Preceding gene: 41408151

Following gene: 41408155

Centisome position: 46.87

GC content: 70.65

Gene sequence:

>1206_bases
GTGACGTTTAACCCGTTCGAGGAACTCACGCTGGACCAACTGCGGCTTCGCACCAGCATGAAATGGCGTGCCCATCCCGC
CGACGTGCTGCCGCTGTGGGTCGCCGAGATGGACGTCAGGCTGGCGCCGACGGTGGCGCAGGCGCTGCGAACGGCGATCG
ACAACGGCGACACCGGCTACCCCTGCGGCACCGCGTTCGCCGAGGCGGTGAGCGAATTCGCGGCGCGGCGTTGGCAGTGG
CACGACCTCGACGTGCGCCGCACCGCGCTGGTTCCCGACGTCATGCTCGGCGCCGTCGAGGTGCTGCGCCTGGTCACCGA
CCCGGGCGACGCCGTCGTCGTCAACCCGCCGGTGTACGCGCCGTTCTACGCATTCGTGTCGCACGACGGCCGCCGGGTCG
TCGAGGCACCGCTAGGCGACGGCGGCCGAATTGACTTGGGCGCGTTGGAAGAAGCGTTCGCACACGCCCGCTCCGGGAAC
ACGGCGAAGGTCGCCTACCTGTTGTGCAATCCGCACAACCCGACCGGGTCGGTGCACACCGCCGCGGAGCTGCGCGGAGT
TGCCGAGCTCGCCCGCCGGTTCGGCGTGCGCGTGGTGTCGGACGAGATCCACGCGCCGGTGATCTTGCCGGGATCACGAT
TCACCCCCTTCCTGACCGTGGCCGGGGCGGAGAACGCCTTCGCGCTGACCTCGGCATCCAAGGCCTGGAACCTGTCCGGC
CTGAAGGCGGCCCTGGCCATCGCCGGACCGGAGGCGGCGGCCGACCTGAACCGGATGCCGGAGGAGGTCAGTCACGGGCC
CAGCCATCTCGGCGTCATCGCCCACACCGAGGCATTCCGCAGCGGTGACGGATGGCTGGACGCCACGCTGCAGGGCCTGG
ACCAGAACCGCGCGTTGCTCGGCGAGCTGGTGGCCGAACATCTTCCGGGCGTGAAATATCAATGGCCGCAAGGCACTTAC
CTCGCGTGGCTGGACTGCCGAGAGCTGGGCTTCGCCGAGGACGCCGCACAGGGCCTGGCCGTGGTCGCCGACCTGTCCGG
GCCCGCGCGCTGGTTCCTCGAGCACGCCCGGGTGGCGCTGAGCTCCGGCCACGTGTTCGGAACCGGCGGGGCTGGACACC
TGCGACTGAACTTCGCCACCTCGCGCGCGATCCTCACCGAGGCGCTGTCGCGCATGGGCCGCGCGCTGGCCGGCCGGTCC
GGCTAG

Upstream 100 bases:

>100_bases
AAGGCGTAAAGCGGCAGCGTGGTCGGGATCTCTAGCGAGCACGGCAGCCGGGGTACGGCCGCGACCACGTTCGCTCACTG
AACTGCCTTAATCTGCCCGA

Downstream 100 bases:

>100_bases
CCCCGCCCGCGCTACGCGGGAATCTCCTCCCCGCCCCGGCCCAAGTTGCGGAACCCTTCCGCGGGCTCCTTCATGCCCAG
GGTGAACGGCAGCGAGTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: CBL; Beta-cystathionase; Cysteine lyase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTFNPFEELTLDQLRLRTSMKWRAHPADVLPLWVAEMDVRLAPTVAQALRTAIDNGDTGYPCGTAFAEAVSEFAARRWQW
HDLDVRRTALVPDVMLGAVEVLRLVTDPGDAVVVNPPVYAPFYAFVSHDGRRVVEAPLGDGGRIDLGALEEAFAHARSGN
TAKVAYLLCNPHNPTGSVHTAAELRGVAELARRFGVRVVSDEIHAPVILPGSRFTPFLTVAGAENAFALTSASKAWNLSG
LKAALAIAGPEAAADLNRMPEEVSHGPSHLGVIAHTEAFRSGDGWLDATLQGLDQNRALLGELVAEHLPGVKYQWPQGTY
LAWLDCRELGFAEDAAQGLAVVADLSGPARWFLEHARVALSSGHVFGTGGAGHLRLNFATSRAILTEALSRMGRALAGRS
G

Sequences:

>Translated_401_residues
MTFNPFEELTLDQLRLRTSMKWRAHPADVLPLWVAEMDVRLAPTVAQALRTAIDNGDTGYPCGTAFAEAVSEFAARRWQW
HDLDVRRTALVPDVMLGAVEVLRLVTDPGDAVVVNPPVYAPFYAFVSHDGRRVVEAPLGDGGRIDLGALEEAFAHARSGN
TAKVAYLLCNPHNPTGSVHTAAELRGVAELARRFGVRVVSDEIHAPVILPGSRFTPFLTVAGAENAFALTSASKAWNLSG
LKAALAIAGPEAAADLNRMPEEVSHGPSHLGVIAHTEAFRSGDGWLDATLQGLDQNRALLGELVAEHLPGVKYQWPQGTY
LAWLDCRELGFAEDAAQGLAVVADLSGPARWFLEHARVALSSGHVFGTGGAGHLRLNFATSRAILTEALSRMGRALAGRS
G
>Mature_400_residues
TFNPFEELTLDQLRLRTSMKWRAHPADVLPLWVAEMDVRLAPTVAQALRTAIDNGDTGYPCGTAFAEAVSEFAARRWQWH
DLDVRRTALVPDVMLGAVEVLRLVTDPGDAVVVNPPVYAPFYAFVSHDGRRVVEAPLGDGGRIDLGALEEAFAHARSGNT
AKVAYLLCNPHNPTGSVHTAAELRGVAELARRFGVRVVSDEIHAPVILPGSRFTPFLTVAGAENAFALTSASKAWNLSGL
KAALAIAGPEAAADLNRMPEEVSHGPSHLGVIAHTEAFRSGDGWLDATLQGLDQNRALLGELVAEHLPGVKYQWPQGTYL
AWLDCRELGFAEDAAQGLAVVADLSGPARWFLEHARVALSSGHVFGTGGAGHLRLNFATSRAILTEALSRMGRALAGRSG

Specific function: Acts As A Beta-Cystathionase And As A Repressor Of The Maltose Regulon. [C]

COG id: COG1168

COG function: function code E; Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787909, Length=382, Percent_Identity=31.151832460733, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =4.4.1.8 [H]

Molecular weight: Translated: 42951; Mature: 42820

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFNPFEELTLDQLRLRTSMKWRAHPADVLPLWVAEMDVRLAPTVAQALRTAIDNGDTGY
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEECHHHHHHHHHHHCCCCCCC
PCGTAFAEAVSEFAARRWQWHDLDVRRTALVPDVMLGAVEVLRLVTDPGDAVVVNPPVYA
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCH
PFYAFVSHDGRRVVEAPLGDGGRIDLGALEEAFAHARSGNTAKVAYLLCNPHNPTGSVHT
HHHHHHCCCCCEEEECCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCH
AAELRGVAELARRFGVRVVSDEIHAPVILPGSRFTPFLTVAGAENAFALTSASKAWNLSG
HHHHHHHHHHHHHHCCEEEECCCCCCEEECCCCCCCEEEEECCCCCEEEECCCCCCCCCC
LKAALAIAGPEAAADLNRMPEEVSHGPSHLGVIAHTEAFRSGDGWLDATLQGLDQNRALL
HHEEEEECCCHHHHHHHHCCHHHCCCCCCEEEEEEHHHHHCCCCHHHHHHHCCCCCHHHH
GELVAEHLPGVKYQWPQGTYLAWLDCRELGFAEDAAQGLAVVADLSGPARWFLEHARVAL
HHHHHHHCCCCEEECCCCCEEEEEEHHHCCCHHHHHCCEEEEEECCCHHHHHHHHHHHHH
SSGHVFGTGGAGHLRLNFATSRAILTEALSRMGRALAGRSG
CCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TFNPFEELTLDQLRLRTSMKWRAHPADVLPLWVAEMDVRLAPTVAQALRTAIDNGDTGY
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEECHHHHHHHHHHHCCCCCCC
PCGTAFAEAVSEFAARRWQWHDLDVRRTALVPDVMLGAVEVLRLVTDPGDAVVVNPPVYA
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCH
PFYAFVSHDGRRVVEAPLGDGGRIDLGALEEAFAHARSGNTAKVAYLLCNPHNPTGSVHT
HHHHHHCCCCCEEEECCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCH
AAELRGVAELARRFGVRVVSDEIHAPVILPGSRFTPFLTVAGAENAFALTSASKAWNLSG
HHHHHHHHHHHHHHCCEEEECCCCCCEEECCCCCCCEEEEECCCCCEEEECCCCCCCCCC
LKAALAIAGPEAAADLNRMPEEVSHGPSHLGVIAHTEAFRSGDGWLDATLQGLDQNRALL
HHEEEEECCCHHHHHHHHCCHHHCCCCCCEEEEEEHHHHHCCCCHHHHHHHCCCCCHHHH
GELVAEHLPGVKYQWPQGTYLAWLDCRELGFAEDAAQGLAVVADLSGPARWFLEHARVAL
HHHHHHHCCCCEEECCCCCEEEEEEHHHCCCHHHHHCCEEEEEECCCHHHHHHHHHHHHH
SSGHVFGTGGAGHLRLNFATSRAILTEALSRMGRALAGRSG
CCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]