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The map label for this gene is fadE20_1

Identifier: 41407811

GI number: 41407811

Start: 1871085

End: 1872248

Strand: Direct

Name: fadE20_1

Synonym: MAP1713

Alternate gene names: 41407811

Gene position: 1871085-1872248 (Clockwise)

Preceding gene: 41407810

Following gene: 41407812

Centisome position: 38.74

GC content: 63.75

Gene sequence:

>1164_bases
ATGTCCGAATTGTTTCCCGATTACCGTCCGCGTTGGGAGACCGACCAGCACCGCGAGCTGCGCAAGCACGCCGCGGAGTT
CTTCCGCAAGGAGGCCACCCCGAACCAGGAACGCTGGGCCGCCCAACACGCGGTCGATCGCGAGTTCTGGAACAAAGCCG
GGGATGCCGGTTTGCTGGGCCTGGACCTGCCCGAGGAATACGGCGGCGCGGGCGGCGACTTCGCGATGAACGTCGTCGTG
CAGGAGGAGCTGGCCTACGCCTACGACCAGGGCTTTGGATTCGCCGTGCACTCGCCGATCGTCGCGCACTACATCTGGGC
CTATGGCAGCGACGAGCAGCGCAGGCGGTGGCTGCCCAAGATCATCAGCGGTGAGGCGGTGTTGGCCATCGCGATGACCG
AACCAGGTACCGGGTCGGATCTGCAATCGGTGAAGACCACCGCGCGGCGCGACGGCGACTTCTACGTCATCAACGGGTCG
AAGACGTTCATCTCCAATGGAACTCACTGCGACCTGTTGGTGATCGTGGCCAAGACCGACCCGTCGAAGGGGGCTGCCGG
GGTGTCGTTGATCGTGGCCGAAACCGACGAGAACCTGGCGGGTTTCGAGCGTGGCCGGGTGCTGGCCAAGATGGGCCAGC
ACGCGCAGGACACCCGCGAGCTGTTCTTCTCCGACATGCGGGTGCCGGTGGCCAACCTGCTCGGCGCGCAGGAGGGTCTG
GGCTTTTACCAATTGATGGAGCAGCTTGCCCGCGAACGGCTCATCATCGCGACAATCTGCGAGGCGCTCGCCGAGGTCGC
GGTGCTCGAGGCGATCAAGTACTCGCGAGAGCGGGAGGCGTTCGGCCGGCCGATCGGCAAGTTCCAGCACACCAAATTCG
TACTGGCCGAATGCAAAACGGAGGCGCTGGCGATCAAGACGATGGTGGACTACGCCGTCGGGCAGTACCTCGACGGCAAG
AACGACCCGGCCACCGCGTCGATGGCCAAGCTGTTCGCCGCCGAGAAGAGCGACCAGATCGTCGACAAGTGCCTGCAGAT
CTTCGGGGGCTACGGCTACATGACCGAGTATCCGATCGCCAACATGTACACCGCGTCGCGGGTCAACCGGATCTATGGCG
GTACCAGCGAAATCATGAAGGAAATCATCAGCCGCTCGCTGTAA

Upstream 100 bases:

>100_bases
GTCACGAAAGCCTGGGTGCGGCGTTCGCGGCCAAGACCACCGCCGAGCTGGAAGACCTTGCGCGGCATATGGATATTCCC
CTGAACGAAGTGAGGTAGAT

Downstream 100 bases:

>100_bases
GGACGTTGAATTGACTGAGGCATACATTTACGAGGGAATCCGCACCCCGCGGGGCAAGGGCAGAGCCAGCGGTGCGCTGC
ATTCCGTGAAGCCGATCTCG

Product: FadE20_1

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSELFPDYRPRWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVDREFWNKAGDAGLLGLDLPEEYGGAGGDFAMNVVV
QEELAYAYDQGFGFAVHSPIVAHYIWAYGSDEQRRRWLPKIISGEAVLAIAMTEPGTGSDLQSVKTTARRDGDFYVINGS
KTFISNGTHCDLLVIVAKTDPSKGAAGVSLIVAETDENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGL
GFYQLMEQLARERLIIATICEALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVLAECKTEALAIKTMVDYAVGQYLDGK
NDPATASMAKLFAAEKSDQIVDKCLQIFGGYGYMTEYPIANMYTASRVNRIYGGTSEIMKEIISRSL

Sequences:

>Translated_387_residues
MSELFPDYRPRWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVDREFWNKAGDAGLLGLDLPEEYGGAGGDFAMNVVV
QEELAYAYDQGFGFAVHSPIVAHYIWAYGSDEQRRRWLPKIISGEAVLAIAMTEPGTGSDLQSVKTTARRDGDFYVINGS
KTFISNGTHCDLLVIVAKTDPSKGAAGVSLIVAETDENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGL
GFYQLMEQLARERLIIATICEALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVLAECKTEALAIKTMVDYAVGQYLDGK
NDPATASMAKLFAAEKSDQIVDKCLQIFGGYGYMTEYPIANMYTASRVNRIYGGTSEIMKEIISRSL
>Mature_386_residues
SELFPDYRPRWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVDREFWNKAGDAGLLGLDLPEEYGGAGGDFAMNVVVQ
EELAYAYDQGFGFAVHSPIVAHYIWAYGSDEQRRRWLPKIISGEAVLAIAMTEPGTGSDLQSVKTTARRDGDFYVINGSK
TFISNGTHCDLLVIVAKTDPSKGAAGVSLIVAETDENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGLG
FYQLMEQLARERLIIATICEALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVLAECKTEALAIKTMVDYAVGQYLDGKN
DPATASMAKLFAAEKSDQIVDKCLQIFGGYGYMTEYPIANMYTASRVNRIYGGTSEIMKEIISRSL

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=44.2970822281167, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=33.0687830687831, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI226958414, Length=343, Percent_Identity=34.402332361516, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=33.3333333333333, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=33.1564986737401, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=31.283422459893, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=31.283422459893, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=30.3191489361702, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI76496475, Length=397, Percent_Identity=30.4785894206549, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI4557235, Length=397, Percent_Identity=30.4785894206549, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI21361497, Length=392, Percent_Identity=28.8265306122449, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI4503943, Length=346, Percent_Identity=28.3236994219653, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI7669494, Length=318, Percent_Identity=28.9308176100629, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI38505218, Length=367, Percent_Identity=25.8855585831063, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI211971008, Length=406, Percent_Identity=25.3694581280788, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI48976061, Length=406, Percent_Identity=25.3694581280788, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI87081958, Length=343, Percent_Identity=31.1953352769679, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1786223, Length=370, Percent_Identity=28.3783783783784, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87082384, Length=270, Percent_Identity=25.5555555555556, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=36.5079365079365, Blast_Score=228, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17570075, Length=377, Percent_Identity=35.0132625994695, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=32.6259946949602, Blast_Score=204, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17534899, Length=377, Percent_Identity=32.8912466843501, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=32, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17533517, Length=368, Percent_Identity=32.6086956521739, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=330, Percent_Identity=34.2424242424242, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17505929, Length=381, Percent_Identity=31.758530183727, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=331, Percent_Identity=31.4199395770393, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=289, Percent_Identity=34.6020761245675, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=30.4843304843305, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71985192, Length=283, Percent_Identity=31.8021201413428, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=31.7596566523605, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71982178, Length=287, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=389, Percent_Identity=26.9922879177378, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=371, Percent_Identity=25.3369272237197, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=27.9835390946502, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21355753, Length=390, Percent_Identity=34.8717948717949, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24660351, Length=392, Percent_Identity=32.9081632653061, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=29.4429708222812, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=30.6666666666667, Blast_Score=171, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24646207, Length=377, Percent_Identity=31.0344827586207, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281363737, Length=397, Percent_Identity=27.9596977329975, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19920834, Length=380, Percent_Identity=27.1052631578947, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43056; Mature: 42925

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELFPDYRPRWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVDREFWNKAGDAGLLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
LDLPEEYGGAGGDFAMNVVVQEELAYAYDQGFGFAVHSPIVAHYIWAYGSDEQRRRWLPK
CCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
IISGEAVLAIAMTEPGTGSDLQSVKTTARRDGDFYVINGSKTFISNGTHCDLLVIVAKTD
HHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCEEEEEEEEECC
PSKGAAGVSLIVAETDENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGL
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCC
GFYQLMEQLARERLIIATICEALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVLAECKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EALAIKTMVDYAVGQYLDGKNDPATASMAKLFAAEKSDQIVDKCLQIFGGYGYMTEYPIA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCH
NMYTASRVNRIYGGTSEIMKEIISRSL
HHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SELFPDYRPRWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVDREFWNKAGDAGLLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
LDLPEEYGGAGGDFAMNVVVQEELAYAYDQGFGFAVHSPIVAHYIWAYGSDEQRRRWLPK
CCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
IISGEAVLAIAMTEPGTGSDLQSVKTTARRDGDFYVINGSKTFISNGTHCDLLVIVAKTD
HHCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCEEEEEEEEECC
PSKGAAGVSLIVAETDENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGL
CCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCC
GFYQLMEQLARERLIIATICEALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVLAECKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EALAIKTMVDYAVGQYLDGKNDPATASMAKLFAAEKSDQIVDKCLQIFGGYGYMTEYPIA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCH
NMYTASRVNRIYGGTSEIMKEIISRSL
HHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]