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The map label for this gene is pgsA2

Identifier: 41407633

GI number: 41407633

Start: 1687021

End: 1687662

Strand: Direct

Name: pgsA2

Synonym: MAP1535

Alternate gene names: 41407633

Gene position: 1687021-1687662 (Clockwise)

Preceding gene: 41407632

Following gene: 41407634

Centisome position: 34.93

GC content: 69.47

Gene sequence:

>642_bases
ATGTCACGGCACATGGAGCCGGTGCTTCCACCCAACCGGGTGCTGACGGTGCCCAACGCGCTCAGCGCGATCCGCCTGGC
GCTCGTCCCCGTGTTCGTCTACGCGTTGCTGGTCGCCCACGCCAACGGGTGGGCGGTGGCGATCCTGATGTTCAGCGGCG
CCTCGGACTGGGCCGACGGCAAAATCGCCCGGCTGCTCAACCAGTCCTCGCGGCTGGGTGTGCTGCTCGACCCCGCGGTG
GACCGCCTCTACATGGTGGTCGTGCCCGTGGTCCTGGCGTTGAGCGGCATCGTGCCGTGGTGGTTCGTCGTGGTCCTGCT
CGTCCGCGACGGCCTGTTGGCCGCCACGCTGCCGCTGCTGTGGAGCCGCGGCCTGTCGGCGCTGCCGGTGACCTACATCG
GCAAGGCGGCGATGTTCGCGTTGATGTCCGGGTTCCCGCTGGTGCTGTTGGGCACCTGGGACGCGTTGTGGAGCCGGGTG
GTGGGCGCCTGCGGCTGGGCCTTCCTGATCTGGGGCCTGTACGCGTACCTGTGGGCGTTCGCGCAGTACGCGGTGCAGAT
GACGCTGGTGGTGCGCCGGATGCCCAAGGTCGATCGCGCGGCACGCCCGTCGACCATGGCGAAGGTCGTCGACCATGGCT
GA

Upstream 100 bases:

>100_bases
CAACCCGCTGTCGGACGACACGCTGTCCACCCTGAGCCTGCCCGGGGTGTTCCGCTAGCCGGTGCGCGGCCAGCCGCGCA
CGGGGCGCCGCGCTTGGCTA

Downstream 100 bases:

>100_bases
CGTGGACCGCGCGCTCGGCGGCTATGACCCCAACGCCGGTCACAGCGCGCACCTAGCGGCGCGCCCGCAGCGGATTCCGG
TGCCCTCGCTGCTGCGCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSRHMEPVLPPNRVLTVPNALSAIRLALVPVFVYALLVAHANGWAVAILMFSGASDWADGKIARLLNQSSRLGVLLDPAV
DRLYMVVVPVVLALSGIVPWWFVVVLLVRDGLLAATLPLLWSRGLSALPVTYIGKAAMFALMSGFPLVLLGTWDALWSRV
VGACGWAFLIWGLYAYLWAFAQYAVQMTLVVRRMPKVDRAARPSTMAKVVDHG

Sequences:

>Translated_213_residues
MSRHMEPVLPPNRVLTVPNALSAIRLALVPVFVYALLVAHANGWAVAILMFSGASDWADGKIARLLNQSSRLGVLLDPAV
DRLYMVVVPVVLALSGIVPWWFVVVLLVRDGLLAATLPLLWSRGLSALPVTYIGKAAMFALMSGFPLVLLGTWDALWSRV
VGACGWAFLIWGLYAYLWAFAQYAVQMTLVVRRMPKVDRAARPSTMAKVVDHG
>Mature_212_residues
SRHMEPVLPPNRVLTVPNALSAIRLALVPVFVYALLVAHANGWAVAILMFSGASDWADGKIARLLNQSSRLGVLLDPAVD
RLYMVVVPVVLALSGIVPWWFVVVLLVRDGLLAATLPLLWSRGLSALPVTYIGKAAMFALMSGFPLVLLGTWDALWSRVV
GACGWAFLIWGLYAYLWAFAQYAVQMTLVVRRMPKVDRAARPSTMAKVVDHG

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 23293; Mature: 23162

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHMEPVLPPNRVLTVPNALSAIRLALVPVFVYALLVAHANGWAVAILMFSGASDWADG
CCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCH
KIARLLNQSSRLGVLLDPAVDRLYMVVVPVVLALSGIVPWWFVVVLLVRDGLLAATLPLL
HHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
WSRGLSALPVTYIGKAAMFALMSGFPLVLLGTWDALWSRVVGACGWAFLIWGLYAYLWAF
HHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQYAVQMTLVVRRMPKVDRAARPSTMAKVVDHG
HHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
SRHMEPVLPPNRVLTVPNALSAIRLALVPVFVYALLVAHANGWAVAILMFSGASDWADG
CCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCH
KIARLLNQSSRLGVLLDPAVDRLYMVVVPVVLALSGIVPWWFVVVLLVRDGLLAATLPLL
HHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
WSRGLSALPVTYIGKAAMFALMSGFPLVLLGTWDALWSRVVGACGWAFLIWGLYAYLWAF
HHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQYAVQMTLVVRRMPKVDRAARPSTMAKVVDHG
HHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]