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The map label for this gene is secA2

Identifier: 41407632

GI number: 41407632

Start: 1684645

End: 1686978

Strand: Direct

Name: secA2

Synonym: MAP1534

Alternate gene names: 41407632

Gene position: 1684645-1686978 (Clockwise)

Preceding gene: 41407631

Following gene: 41407633

Centisome position: 34.88

GC content: 69.97

Gene sequence:

>2334_bases
GTGCCTAAGACGAACCGAGCTCAACCCGGCCGGCTGAGCAGCCGATTCTGGCGCCTGCTCGGCGCCAGCACGGAAAAGAA
CCGCAGCCGTTCGCTCACCCTGGTGACCGACTCGTCGGAATACGACGACGAGGCCGCCGGGCTGACCGACGAGCAGCTGC
GCAAGGCCGCCGGGCTGCTCAACCTGGAGGATCTCGCCGAGTCCGAGGACATCCCACAGTTCCTGGCCATCGCCCGGGAG
GCCGCCGAGCGGGCAACGGGCTTGCGCCCATTTGATGTGCAGCTGCTTGGGGCCTTGCGGATGCTGGCCGGCGACGTGAT
CGAGATGGCCACCGGCGAGGGCAAGACCCTGGCCGGGGCGATCGCGGCCGCCGGCTACGTGCTGGCCGGCCGGCACGTGC
ACGTGGTGACCATCAACGACTACCTGGCCCGCCGCGACGCGGAATGGATGGGCCCGCTGATCGAGGCGATGGGGCTCACG
GTCGGCTGGATCACCGCCGAGTCGTCCAGCGAGGAGCGCCGGGCCGCCTACGGCTGCGACGTCACCTACGCCTCGGTCAA
CGAGATCGGCTTCGACGTGCTGCGCGATCAGCTGGTGACCGACGTCGCGGACCTGGTCTCGCCCAACCCCGACGTGGCGC
TGATCGACGAGGCCGACTCGGTGCTGGTCGACGAGGCGCTGGTGCCGCTGGTGCTGGCCGGCACGACGCACCGCGAGACG
CCGCGGCTGGAGATCATCAAGCTGGTCGGCGAGCTGGAGGCCGGCACCGACTACGACACCGACGCCGACAGCCGCAACGT
CCATCTCACCGACGTCGGCGCGCGCAAGGTGGAGAAGGCGCTCGGCGGCATCGACCTGTACTCCGAGGAGCACGTCGGCA
CCACCCTGACCGAGGTCAACGTCGCGCTGCACGCGCACGTGCTGTTGCAGCGCGACGTGCACTACATCGTCCGCGACGAC
GCGGTGCACCTGATCAACGCCTCGCGCGGGCGGATCGCGCAGCTGCAGCGCTGGCCGGACGGCCTGCAGGCCGCCGTCGA
GGCCAAGGAGGGCATCGAGACCACCGAAACCGGGGAGGTGCTCGACACCATCACCGTGCAGGCGTTGATCAACCGGTACG
CCACGGTGTGCGGCATGACCGGCACCGCGCTGGCAGCCGGTGAGCAGCTGCGCCAGTTCTACAAGCTCGGTGTGTCGCCG
ATTCCGCCGAACAAACCCAACATCCGCGAGGACGAGGCCGACCGCGTCTACATCACGGCGGCCGCCAAGAACGACGCGAT
CGTCGAGCACATCATCGAGGTCCACGAAACCGGGCAGCCGGTGCTGGTGGGCACCCGCGACGTGGCCGAATCCGAGGAGC
TGCACGAGCGGCTGCTGCGCCGCGGCGTGCCGGCGGTGGTGCTCAACGCCAAGAACGACGCCGAGGAGGCCCAGGTGATC
GCCGAGGCCGGCAAGTTCGGGGTGGTGACGGTGTCCACCCAGATGGCCGGGCGCGGCACCGACATCCGGCTCGGCGGCTC
CGACGAGGCCGATCACGACCGGGTCGCCGAGCTGGGCGGGCTGCACGTGGTGGGCACCGGCCGGCACCACACCGAGCGGC
TGGACAACCAGCTGCGCGGGCGCGCCGGCCGGCAGGGCGACCCGGGGTCGTCGGTGTTCTTCTCCAGCTGGGAGGACGAC
GTGGTGGCGGCCAACCTCGACCGCAACAAGCTGCCGATGGAAACCGACCCGGAAACGGGCGACGGCCGAATCGTCAGCCC
CAAGGCCGCCGGGCTGCTCGATCACGCCCAGCGCGTCGCCGAGGGCCGCATGCTCGACGTGCACGCGAACACCTGGCGCT
ACAACCAGCTGATCGCCCAGCAGCGCGCGATCATCGTCGACCGCCGTAACACGTTGCTGCGCACCGCAACCGCGCGTGAG
GAGCTGGCGGAGCTGGCGCCGAAGCGCTACCGGGAGCTGGCCGACGAGATCCCCGAGGAACGCCTGGAAACCATCTGCCG
GCACATCATGCTCTACCACCTCGACCGCGGCTGGGCCGACCATCTGGCGTACCTGGCCGACATCCGCGAGAGCATCCACC
TGCGGGCGCTGGGCCGGCAGAATCCGCTGGACGAATTCCACCGGTTGGCGGTCGACGCGTTCGCGTCGCTGGCCGCCGAC
GCGATCGAGGCGGCCCAGCAGACGTTCGAAACCGCCAACGTGCTCGAGGACGAGCCGGGCCTGGATCTGTCCAAGCTGGC
CCGGCCGACGTCGACGTGGACGTACATGGTCAACGACAACCCGCTGTCGGACGACACGCTGTCCACCCTGAGCCTGCCCG
GGGTGTTCCGCTAG

Upstream 100 bases:

>100_bases
CTCACCGACCCCACGGTCGCCTACCCGCGGCGGTCGAACCTGGCCTGACGGGCGTGTCGGGTGCGAACACGCGGGCTCGC
CCCACCGGTACCGTTGACCT

Downstream 100 bases:

>100_bases
CCGGTGCGCGGCCAGCCGCGCACGGGGCGCCGCGCTTGGCTAATGTCACGGCACATGGAGCCGGTGCTTCCACCCAACCG
GGTGCTGACGGTGCCCAACG

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MPKTNRAQPGRLSSRFWRLLGASTEKNRSRSLTLVTDSSEYDDEAAGLTDEQLRKAAGLLNLEDLAESEDIPQFLAIARE
AAERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYVLAGRHVHVVTINDYLARRDAEWMGPLIEAMGLT
VGWITAESSSEERRAAYGCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRET
PRLEIIKLVGELEAGTDYDTDADSRNVHLTDVGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDD
AVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLGVSP
IPPNKPNIREDEADRVYITAAAKNDAIVEHIIEVHETGQPVLVGTRDVAESEELHERLLRRGVPAVVLNAKNDAEEAQVI
AEAGKFGVVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDD
VVAANLDRNKLPMETDPETGDGRIVSPKAAGLLDHAQRVAEGRMLDVHANTWRYNQLIAQQRAIIVDRRNTLLRTATARE
ELAELAPKRYRELADEIPEERLETICRHIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRLAVDAFASLAAD
AIEAAQQTFETANVLEDEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSTLSLPGVFR

Sequences:

>Translated_777_residues
MPKTNRAQPGRLSSRFWRLLGASTEKNRSRSLTLVTDSSEYDDEAAGLTDEQLRKAAGLLNLEDLAESEDIPQFLAIARE
AAERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYVLAGRHVHVVTINDYLARRDAEWMGPLIEAMGLT
VGWITAESSSEERRAAYGCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRET
PRLEIIKLVGELEAGTDYDTDADSRNVHLTDVGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDD
AVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLGVSP
IPPNKPNIREDEADRVYITAAAKNDAIVEHIIEVHETGQPVLVGTRDVAESEELHERLLRRGVPAVVLNAKNDAEEAQVI
AEAGKFGVVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDD
VVAANLDRNKLPMETDPETGDGRIVSPKAAGLLDHAQRVAEGRMLDVHANTWRYNQLIAQQRAIIVDRRNTLLRTATARE
ELAELAPKRYRELADEIPEERLETICRHIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRLAVDAFASLAAD
AIEAAQQTFETANVLEDEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSTLSLPGVFR
>Mature_776_residues
PKTNRAQPGRLSSRFWRLLGASTEKNRSRSLTLVTDSSEYDDEAAGLTDEQLRKAAGLLNLEDLAESEDIPQFLAIAREA
AERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYVLAGRHVHVVTINDYLARRDAEWMGPLIEAMGLTV
GWITAESSSEERRAAYGCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRETP
RLEIIKLVGELEAGTDYDTDADSRNVHLTDVGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDA
VHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLGVSPI
PPNKPNIREDEADRVYITAAAKNDAIVEHIIEVHETGQPVLVGTRDVAESEELHERLLRRGVPAVVLNAKNDAEEAQVIA
EAGKFGVVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDV
VAANLDRNKLPMETDPETGDGRIVSPKAAGLLDHAQRVAEGRMLDVHANTWRYNQLIAQQRAIIVDRRNTLLRTATAREE
LAELAPKRYRELADEIPEERLETICRHIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRLAVDAFASLAADA
IEAAQQTFETANVLEDEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSTLSLPGVFR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=825, Percent_Identity=34.5454545454545, Blast_Score=416, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 85032; Mature: 84901

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTNRAQPGRLSSRFWRLLGASTEKNRSRSLTLVTDSSEYDDEAAGLTDEQLRKAAGLL
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHCCCCHHHHHHHHCCC
NLEDLAESEDIPQFLAIAREAAERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGA
CHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IAAAGYVLAGRHVHVVTINDYLARRDAEWMGPLIEAMGLTVGWITAESSSEERRAAYGCD
HHHHHHHEECCEEEEEEECHHHHHCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHCCCC
VTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRET
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHEEECCCCCCC
PRLEIIKLVGELEAGTDYDTDADSRNVHLTDVGARKVEKALGGIDLYSEEHVGTTLTEVN
CHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHH
VALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEV
HHHHHHHHHHHCHHEEEECCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCHH
LDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLGVSPIPPNKPNIREDEADRVYITA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEE
AAKNDAIVEHIIEVHETGQPVLVGTRDVAESEELHERLLRRGVPAVVLNAKNDAEEAQVI
ECCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
AEAGKFGVVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRG
HHCCCEEEEEEEEECCCCCCEEEECCCCCCCHHHHHHHCCEEEEECCCHHHHHHHHHHHC
RAGRQGDPGSSVFFSSWEDDVVAANLDRNKLPMETDPETGDGRIVSPKAAGLLDHAQRVA
CCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHH
EGRMLDVHANTWRYNQLIAQQRAIIVDRRNTLLRTATAREELAELAPKRYRELADEIPEE
CCCEEEEECCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RLETICRHIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRLAVDAFASLAAD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AIEAAQQTFETANVLEDEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSTLSLPGVFR
HHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
PKTNRAQPGRLSSRFWRLLGASTEKNRSRSLTLVTDSSEYDDEAAGLTDEQLRKAAGLL
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHCCCCHHHHHHHHCCC
NLEDLAESEDIPQFLAIAREAAERATGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGA
CHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IAAAGYVLAGRHVHVVTINDYLARRDAEWMGPLIEAMGLTVGWITAESSSEERRAAYGCD
HHHHHHHEECCEEEEEEECHHHHHCCHHHHHHHHHHHCCEEEEEEECCCCHHHHHHCCCC
VTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRET
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHEEECCCCCCC
PRLEIIKLVGELEAGTDYDTDADSRNVHLTDVGARKVEKALGGIDLYSEEHVGTTLTEVN
CHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHH
VALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEV
HHHHHHHHHHHCHHEEEECCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCHH
LDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLGVSPIPPNKPNIREDEADRVYITA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEE
AAKNDAIVEHIIEVHETGQPVLVGTRDVAESEELHERLLRRGVPAVVLNAKNDAEEAQVI
ECCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
AEAGKFGVVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRG
HHCCCEEEEEEEEECCCCCCEEEECCCCCCCHHHHHHHCCEEEEECCCHHHHHHHHHHHC
RAGRQGDPGSSVFFSSWEDDVVAANLDRNKLPMETDPETGDGRIVSPKAAGLLDHAQRVA
CCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHH
EGRMLDVHANTWRYNQLIAQQRAIIVDRRNTLLRTATAREELAELAPKRYRELADEIPEE
CCCEEEEECCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RLETICRHIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRLAVDAFASLAAD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AIEAAQQTFETANVLEDEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSTLSLPGVFR
HHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]