| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG [H]
Identifier: 41406807
GI number: 41406807
Start: 734143
End: 734952
Strand: Direct
Name: fabG [H]
Synonym: MAP0709
Alternate gene names: 41406807
Gene position: 734143-734952 (Clockwise)
Preceding gene: 41406806
Following gene: 41406811
Centisome position: 15.2
GC content: 70.37
Gene sequence:
>810_bases ATGGCCATCGATCCCTCGGACATCCTGCTCACCGACCGGGTCGCGGTGGTGACCGGGGCGGGGGCGGGCATCGGCCGCGG CATCGCCGCCGGGCTGGCCGCATTCGGCGCGCGGGTGGCGATCTGGGAGCGCGACGCGCAAACCTGCACGCGGGCAGCCG AATCCATCGGAGGACTGGGCATCGTCACCGACGTGCGGGACAGCGGCCAGGTCGACGCCGCGCTGCAGCGCACCATCACC GAACTGGGCACGCCCGCCATCCTGGTGAACAATGCCGGCGGGGTGTTCTCCTCGCCGCTGCTGGAAACCAGCGAGAACGG CTGGGATGCGCTCTACCGCGCCAATCTTCGGCACGTGCTGCTGTGCACCCAGCGGATCGCCCGGCAGCTGGTGTCGGTGG GCGCCGGCGGCAGCATCATCTCGCTGACCTCCATCGAAGGCGTGCGCGCGGCACCGGGCTATGCCGCCTACGCGGCGGCC AAGGCCGGCGTCATCAACTACACCAAGACCGCGGCGCTGGAACTGGCGCCGCACGGCATCCGGGTCAACGCGATCGCGCC CGACATCACGCTCACCGAAGGGCTGGAACAGCTAGGCGGTGAGGCCGCCACCACCGCGATGGGGAACATCGTTCCGCTGG GCCGTCCCGGCCACGTCGACGAAATCGCCAGTGCCGCAGTCTTTTTGGCTTCCGACATGTCGGGGTACCTGACGGGGCAG ACGCTGCACGTCGACGGCGGCACCCAGGCCTCCAGCGGGTGGTATCACGATCCGCGGACCGGCGACTACCGACTGGGCCC GGCCGGTTAG
Upstream 100 bases:
>100_bases GCTGTCCGGGCTGGGCTTGTCCGACGCGGACATCGCGACGCTGCGGGCCGAAGGTGTCATCGGCAGCGCGCCGGCCATAC ACCCGGCGGGCTGACCGGCG
Downstream 100 bases:
>100_bases CTCACCGACGCTGCCGCAACAGCCCCGAGGGCCCGGCCCCATTTATCTAGTGCGTCCAGCCCTCGGCGGCCTGCTCGTCG AAGGTCCGGTCGATGCGTTC
Product: hypothetical protein
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 269; Mature: 268
Protein sequence:
>269_residues MAIDPSDILLTDRVAVVTGAGAGIGRGIAAGLAAFGARVAIWERDAQTCTRAAESIGGLGIVTDVRDSGQVDAALQRTIT ELGTPAILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIARQLVSVGAGGSIISLTSIEGVRAAPGYAAYAAA KAGVINYTKTAALELAPHGIRVNAIAPDITLTEGLEQLGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSGYLTGQ TLHVDGGTQASSGWYHDPRTGDYRLGPAG
Sequences:
>Translated_269_residues MAIDPSDILLTDRVAVVTGAGAGIGRGIAAGLAAFGARVAIWERDAQTCTRAAESIGGLGIVTDVRDSGQVDAALQRTIT ELGTPAILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIARQLVSVGAGGSIISLTSIEGVRAAPGYAAYAAA KAGVINYTKTAALELAPHGIRVNAIAPDITLTEGLEQLGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSGYLTGQ TLHVDGGTQASSGWYHDPRTGDYRLGPAG >Mature_268_residues AIDPSDILLTDRVAVVTGAGAGIGRGIAAGLAAFGARVAIWERDAQTCTRAAESIGGLGIVTDVRDSGQVDAALQRTITE LGTPAILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIARQLVSVGAGGSIISLTSIEGVRAAPGYAAYAAAK AGVINYTKTAALELAPHGIRVNAIAPDITLTEGLEQLGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSGYLTGQT LHVDGGTQASSGWYHDPRTGDYRLGPAG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=35.7429718875502, Blast_Score=135, Evalue=3e-32, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=36.1867704280156, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI19923817, Length=272, Percent_Identity=30.8823529411765, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=30.8943089430894, Blast_Score=105, Evalue=6e-23, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=34.0080971659919, Blast_Score=105, Evalue=6e-23, Organism=Homo sapiens, GI4503301, Length=238, Percent_Identity=32.3529411764706, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=30, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=31.7269076305221, Blast_Score=90, Evalue=3e-18, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=33.6633663366337, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=29.6875, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=33.920704845815, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=30.4812834224599, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=32.9896907216495, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=32.7485380116959, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI142976729, Length=192, Percent_Identity=26.5625, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=5e-12, Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=38.3333333333333, Blast_Score=137, Evalue=6e-34, Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=35.655737704918, Blast_Score=130, Evalue=9e-32, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=34.8, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.9206349206349, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=33.6134453781513, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=30.7086614173228, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=34.1463414634146, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=32.6612903225806, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=32.8, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=30.0411522633745, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=28.6274509803922, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=41.5637860082305, Blast_Score=154, Evalue=5e-38, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=38.8663967611336, Blast_Score=139, Evalue=1e-33, Organism=Caenorhabditis elegans, GI17561272, Length=251, Percent_Identity=37.4501992031873, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=32.9365079365079, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=31.0344827586207, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=32.0754716981132, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=33.9483394833948, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=32.1705426356589, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=33.7301587301587, Blast_Score=111, Evalue=5e-25, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=30.8300395256917, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=30.5555555555556, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=31.3207547169811, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=30.4511278195489, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=31.8681318681319, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17536651, Length=265, Percent_Identity=30.188679245283, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=30.2583025830258, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=30.6513409961686, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=31.2977099236641, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=30.4347826086957, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=30.8823529411765, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=30.1526717557252, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=28.996282527881, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=28.90625, Blast_Score=98, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=29.9270072992701, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=28.9473684210526, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=29.0076335877863, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.4681647940075, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=28.8617886178862, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI71982365, Length=208, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508895, Length=242, Percent_Identity=23.5537190082645, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17568967, Length=255, Percent_Identity=25.0980392156863, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193203117, Length=237, Percent_Identity=22.3628691983122, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI193203115, Length=237, Percent_Identity=22.3628691983122, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=30.9236947791165, Blast_Score=100, Evalue=5e-22, Organism=Saccharomyces cerevisiae, GI6322861, Length=229, Percent_Identity=28.3842794759825, Blast_Score=70, Evalue=4e-13, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=35.9683794466403, Blast_Score=137, Evalue=5e-33, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=36.5079365079365, Blast_Score=130, Evalue=8e-31, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=34.6613545816733, Blast_Score=130, Evalue=1e-30, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=33.8709677419355, Blast_Score=125, Evalue=2e-29, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=33.739837398374, Blast_Score=117, Evalue=8e-27, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=34.375, Blast_Score=114, Evalue=7e-26, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=32.258064516129, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI24644337, Length=197, Percent_Identity=32.48730964467, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=33.1632653061224, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI161076933, Length=183, Percent_Identity=32.7868852459016, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584748, Length=183, Percent_Identity=32.7868852459016, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27430; Mature: 27299
Theoretical pI: Translated: 5.03; Mature: 5.03
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAIDPSDILLTDRVAVVTGAGAGIGRGIAAGLAAFGARVAIWERDAQTCTRAAESIGGLG CCCCCCCEEEECCEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCE IVTDVRDSGQVDAALQRTITELGTPAILVNNAGGVFSSPLLETSENGWDALYRANLRHVL EEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHCCCCCHHHHHHHCHHHHH LCTQRIARQLVSVGAGGSIISLTSIEGVRAAPGYAAYAAAKAGVINYTKTAALELAPHGI HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEECCHHEEEEECCCCE RVNAIAPDITLTEGLEQLGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSGYLTGQ EEEEECCCCHHHHHHHHHCCHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEECC TLHVDGGTQASSGWYHDPRTGDYRLGPAG EEEECCCCCCCCCCCCCCCCCCEECCCCC >Mature Secondary Structure AIDPSDILLTDRVAVVTGAGAGIGRGIAAGLAAFGARVAIWERDAQTCTRAAESIGGLG CCCCCCEEEECCEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCE IVTDVRDSGQVDAALQRTITELGTPAILVNNAGGVFSSPLLETSENGWDALYRANLRHVL EEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHCCCCCHHHHHHHCHHHHH LCTQRIARQLVSVGAGGSIISLTSIEGVRAAPGYAAYAAAKAGVINYTKTAALELAPHGI HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEECCHHEEEEECCCCE RVNAIAPDITLTEGLEQLGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMSGYLTGQ EEEEECCCCHHHHHHHHHCCHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEECC TLHVDGGTQASSGWYHDPRTGDYRLGPAG EEEECCCCCCCCCCCCCCCCCCEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]