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The map label for this gene is pepQ [H]

Identifier: 41406804

GI number: 41406804

Start: 729391

End: 730569

Strand: Direct

Name: pepQ [H]

Synonym: MAP0706

Alternate gene names: 41406804

Gene position: 729391-730569 (Clockwise)

Preceding gene: 41406803

Following gene: 41406805

Centisome position: 15.1

GC content: 69.04

Gene sequence:

>1179_bases
CTGCGCCGCGACACCGGAACCCGGCTCCGGGCGGCGATGGCCGAGCGCGGCGTCGACGCGATGATCCTGCTCGGCAACAA
CGCCGTCGTCTATGCCACCGGCGCCAGTTGGCCACTCGGCGACGCCGGGCTGTCCTATGTCGAGCGCCCGGTGGCCGTGG
TGCTCGCCGACGACGAATGGCCGCACCTGTTCCTGCCGTTCCGCGAGGGCGCCGCACACGAGTCGGACCTGCCCGCCGAC
CATCTGCACGGGCCGGTCTATCTCGAATTCGACGAAGGCGTCGCGGCTTTCGCGCGCACGGTCGCCGACCTGATTCCGGC
CAACGCCGTGATCGCGGTCGACGAATGCACCGGCGCAATGTCCCGCGCGGCCGCGACGCTGTTCCCCCGCGGCGCCCCCG
TCGACGCGGCGGCCATCGTCGGCGCCGCCAAGGCGGTCAAGACACCGGACGAGTTGTCGTGCATCCGCACCGCGATCCGG
ATCACCGACGAGGCGATGGTCGAGGTACAGAAGCGGCTGGCCCCCGGTATCCGCCAAATCGACTTGTCGGCAAGCTTTTT
GCGGCGCGCCTTCGAGCTGGGCGCCACGGCCAGCATGCTGGAACCGATCTGGCAGGTGATGCCGCCGAGCAAGGCCGAGG
GGGTATGGACCACGCACGGCGACCTGGCGCTGCCGCTGCTGTCCACCGCGCGCGAGCTCGACGAAGGCGACGTGCTGTGG
ACCGACGTCAGCATCACCTACCAGGGCTACTGCTCGGACTTCGGCCGCACCTGGATCGTCGGGCGGGACCCGTCGCCGCG
CCAACAGGCCCAGTTCGACAAGTGGTTCGAAATCATGACCGCGGTTCTGGATGTCGCCAAGGCCGGCGCCACCGCGGCCG
ATCTGGGCCGGGCCGCGATCGGGGCCAACGGCGGTGCGAAGCCGTGGCTGCCGCACTTCTACCTGGGCCACGGCATCGGC
GTCAACGCCGCCGAAATGCCCATGATCGGAACCGATCTCGGCCAGGAGTTCGACGAGAACTTCGTCCTGCAAGCCGGGAT
GGTGCTGGTGCTGGAGCCGGTGGTGTGGGAGGACGGCACCGGCGGCTACCGCAGCGAAGAGGTTCTGGTGATCACCGAGG
AGGGCTGGATCCGCTTGACCGACTACCCCTATGACCCGTATGGCCGTCATGTCAGTTGA

Upstream 100 bases:

>100_bases
ATGTGACGAAATTCCTGGGTTTGTAGTGACGACACTCGCGCATCTGGACACCAAAACCGGTGAAGGGCTGGTGATTCCGG
AGACACCGGACTTGACCCGG

Downstream 100 bases:

>100_bases
AGTCTGCCCCGACGAGCGCACGCTGCGCTCGGGGCGCCGCCGGCGGGCGTTGGACCAGATGGCCGCCCACGACCTCGACG
TGCTGGTGCTCGGTCGGCAG

Product: hypothetical protein

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MRRDTGTRLRAAMAERGVDAMILLGNNAVVYATGASWPLGDAGLSYVERPVAVVLADDEWPHLFLPFREGAAHESDLPAD
HLHGPVYLEFDEGVAAFARTVADLIPANAVIAVDECTGAMSRAAATLFPRGAPVDAAAIVGAAKAVKTPDELSCIRTAIR
ITDEAMVEVQKRLAPGIRQIDLSASFLRRAFELGATASMLEPIWQVMPPSKAEGVWTTHGDLALPLLSTARELDEGDVLW
TDVSITYQGYCSDFGRTWIVGRDPSPRQQAQFDKWFEIMTAVLDVAKAGATAADLGRAAIGANGGAKPWLPHFYLGHGIG
VNAAEMPMIGTDLGQEFDENFVLQAGMVLVLEPVVWEDGTGGYRSEEVLVITEEGWIRLTDYPYDPYGRHVS

Sequences:

>Translated_392_residues
MRRDTGTRLRAAMAERGVDAMILLGNNAVVYATGASWPLGDAGLSYVERPVAVVLADDEWPHLFLPFREGAAHESDLPAD
HLHGPVYLEFDEGVAAFARTVADLIPANAVIAVDECTGAMSRAAATLFPRGAPVDAAAIVGAAKAVKTPDELSCIRTAIR
ITDEAMVEVQKRLAPGIRQIDLSASFLRRAFELGATASMLEPIWQVMPPSKAEGVWTTHGDLALPLLSTARELDEGDVLW
TDVSITYQGYCSDFGRTWIVGRDPSPRQQAQFDKWFEIMTAVLDVAKAGATAADLGRAAIGANGGAKPWLPHFYLGHGIG
VNAAEMPMIGTDLGQEFDENFVLQAGMVLVLEPVVWEDGTGGYRSEEVLVITEEGWIRLTDYPYDPYGRHVS
>Mature_392_residues
MRRDTGTRLRAAMAERGVDAMILLGNNAVVYATGASWPLGDAGLSYVERPVAVVLADDEWPHLFLPFREGAAHESDLPAD
HLHGPVYLEFDEGVAAFARTVADLIPANAVIAVDECTGAMSRAAATLFPRGAPVDAAAIVGAAKAVKTPDELSCIRTAIR
ITDEAMVEVQKRLAPGIRQIDLSASFLRRAFELGATASMLEPIWQVMPPSKAEGVWTTHGDLALPLLSTARELDEGDVLW
TDVSITYQGYCSDFGRTWIVGRDPSPRQQAQFDKWFEIMTAVLDVAKAGATAADLGRAAIGANGGAKPWLPHFYLGHGIG
VNAAEMPMIGTDLGQEFDENFVLQAGMVLVLEPVVWEDGTGGYRSEEVLVITEEGWIRLTDYPYDPYGRHVS

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=245, Percent_Identity=26.1224489795918, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 42334; Mature: 42334

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRDTGTRLRAAMAERGVDAMILLGNNAVVYATGASWPLGDAGLSYVERPVAVVLADDEW
CCCCCHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHCCCEEEEEECCCC
PHLFLPFREGAAHESDLPADHLHGPVYLEFDEGVAAFARTVADLIPANAVIAVDECTGAM
CEEEEECCCCCCCCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHH
SRAAATLFPRGAPVDAAAIVGAAKAVKTPDELSCIRTAIRITDEAMVEVQKRLAPGIRQI
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
DLSASFLRRAFELGATASMLEPIWQVMPPSKAEGVWTTHGDLALPLLSTARELDEGDVLW
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCEEE
TDVSITYQGYCSDFGRTWIVGRDPSPRQQAQFDKWFEIMTAVLDVAKAGATAADLGRAAI
EEEEEEEEEHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHC
GANGGAKPWLPHFYLGHGIGVNAAEMPMIGTDLGQEFDENFVLQAGMVLVLEPVVWEDGT
CCCCCCCCCCCCEECCCCCCCCHHHCCEECCHHHHHHCCCHHHHCCEEEEEEEEEEECCC
GGYRSEEVLVITEEGWIRLTDYPYDPYGRHVS
CCCCCCEEEEEECCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRRDTGTRLRAAMAERGVDAMILLGNNAVVYATGASWPLGDAGLSYVERPVAVVLADDEW
CCCCCHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHCCCEEEEEECCCC
PHLFLPFREGAAHESDLPADHLHGPVYLEFDEGVAAFARTVADLIPANAVIAVDECTGAM
CEEEEECCCCCCCCCCCCHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHH
SRAAATLFPRGAPVDAAAIVGAAKAVKTPDELSCIRTAIRITDEAMVEVQKRLAPGIRQI
HHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
DLSASFLRRAFELGATASMLEPIWQVMPPSKAEGVWTTHGDLALPLLSTARELDEGDVLW
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCEEE
TDVSITYQGYCSDFGRTWIVGRDPSPRQQAQFDKWFEIMTAVLDVAKAGATAADLGRAAI
EEEEEEEEEHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHC
GANGGAKPWLPHFYLGHGIGVNAAEMPMIGTDLGQEFDENFVLQAGMVLVLEPVVWEDGT
CCCCCCCCCCCCEECCCCCCCCHHHCCEECCHHHHHHCCCHHHHCCEEEEEEEEEEECCC
GGYRSEEVLVITEEGWIRLTDYPYDPYGRHVS
CCCCCCEEEEEECCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]