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The map label for this gene is rmlB2

Identifier: 41406528

GI number: 41406528

Start: 458521

End: 459477

Strand: Direct

Name: rmlB2

Synonym: MAP0430

Alternate gene names: 41406528

Gene position: 458521-459477 (Clockwise)

Preceding gene: 41406526

Following gene: 41406532

Centisome position: 9.49

GC content: 69.38

Gene sequence:

>957_bases
ATGTATGGTGGGCCGGTGCGCGCACTGGTTACCGGGGCAGCCGGATTCATCGGCTCGACGCTAGTCGACCGCCTCCTGGC
CGACGGCCACACGGTGGTGGGGCTGGACAACTTCGCGTCCGGCCGCGCGAGCAACCTCGAGCATCTGGTCGGCAACCCGG
CGCACGTGTTCGTCGAGGCCGACATCGTGACCGCCGACCTGGAGGCCATCCTCGACGAACACCGCCCGGAGGTGGTGTTC
CACCTGGCCGCCCAGATCGACGTGCGGCACTCGGTGGCCGACCCGCAATTCGACGCCTCGGTCAACGTCATCGGCACCGT
GCGGCTGGCCGAGGCCGCGCGCCGCACGGGCGTGCGCAAGATGGTGCACACCTCCTCCGGGGGCTCCATCTACGGCACCC
CGCCGACCTATCCCACCCCCGAGACCGTGCCCACCGACCCGGCCTCGCCGTATGCCGCGGGCAAGGTGGCCGGCGAGATC
TACCTGAACACCTTCCGCCACCTCTACGGCCTGGACTGCTCGCACATCGCGCCGGCCAATGTCTATGGGCCGCGCCAGGA
TCCGCACGGCGAGGCCGGTGTGGTGGCGATCTTCGCCCAGGCGCTGCAGTCGGGCAAGCCCACCAAGGTTTTCGGGGACG
GCACCAACACCCGCGACTACGTTTTCGTCGACGACGTGGTGGACGCCTTCGTCAAGGCATCCGGGGACGCCGGCGGCGGC
CAGCGCTTCAACATCGGCACCGGCGTCGAAACCTCGGACCGGCAACTGCATTCGGCCGTCGCGGCCGCCGTCGGGGGACC
CGACGACCCGGAGTTCCACCCGCCGCGGCTCGGCGACCTGAAGCGGTCCTGCCTCGATATCGGCTTAGCCGCAAGAGTTT
TGGGCTGGCAACCGAAGGTCGGCCTGCAGCAGGGGGTGGCCCGCACAGTGGAGTACTTCCGCAACCAGCACAACTAG

Upstream 100 bases:

>100_bases
GCCGATCAGGATCAGGTCGTCCCAATAGAAGTAGCCGCCGAACGCCAGCACCGCGCGCACCGCCAGCTGCACCACGACGA
GCGCGGCGGCCGCCAGGGCT

Downstream 100 bases:

>100_bases
TTCGGGTCGGGAGGCAGCGCGGATTCCAGCGCGACCGCCCGGGCCAGGCGCGCGTAGCGCAGCTCCAGGTCCTTGAACCG
CATATAGGTGCTGAGCGTGG

Product: RmlB2

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MYGGPVRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFASGRASNLEHLVGNPAHVFVEADIVTADLEAILDEHRPEVVF
HLAAQIDVRHSVADPQFDASVNVIGTVRLAEAARRTGVRKMVHTSSGGSIYGTPPTYPTPETVPTDPASPYAAGKVAGEI
YLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALQSGKPTKVFGDGTNTRDYVFVDDVVDAFVKASGDAGGG
QRFNIGTGVETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAARVLGWQPKVGLQQGVARTVEYFRNQHN

Sequences:

>Translated_318_residues
MYGGPVRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFASGRASNLEHLVGNPAHVFVEADIVTADLEAILDEHRPEVVF
HLAAQIDVRHSVADPQFDASVNVIGTVRLAEAARRTGVRKMVHTSSGGSIYGTPPTYPTPETVPTDPASPYAAGKVAGEI
YLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALQSGKPTKVFGDGTNTRDYVFVDDVVDAFVKASGDAGGG
QRFNIGTGVETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAARVLGWQPKVGLQQGVARTVEYFRNQHN
>Mature_318_residues
MYGGPVRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFASGRASNLEHLVGNPAHVFVEADIVTADLEAILDEHRPEVVF
HLAAQIDVRHSVADPQFDASVNVIGTVRLAEAARRTGVRKMVHTSSGGSIYGTPPTYPTPETVPTDPASPYAAGKVAGEI
YLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALQSGKPTKVFGDGTNTRDYVFVDDVVDAFVKASGDAGGG
QRFNIGTGVETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAARVLGWQPKVGLQQGVARTVEYFRNQHN

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=30.1587301587302, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI7657641, Length=327, Percent_Identity=29.6636085626911, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI56237023, Length=328, Percent_Identity=28.6585365853659, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI56118217, Length=328, Percent_Identity=28.6585365853659, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI189083684, Length=328, Percent_Identity=28.6585365853659, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4504031, Length=344, Percent_Identity=26.1627906976744, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=28.9085545722714, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=31.8452380952381, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=28.4431137724551, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788366, Length=353, Percent_Identity=28.6118980169972, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788365, Length=234, Percent_Identity=26.4957264957265, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=324, Percent_Identity=30.8641975308642, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=29.1666666666667, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=31.6860465116279, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71982035, Length=333, Percent_Identity=32.1321321321321, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115532424, Length=335, Percent_Identity=25.3731343283582, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17507723, Length=341, Percent_Identity=25.5131964809384, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI133901790, Length=348, Percent_Identity=25.8620689655172, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI133901788, Length=348, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17539422, Length=348, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17539424, Length=348, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI133901786, Length=348, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=328, Percent_Identity=27.7439024390244, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21356223, Length=320, Percent_Identity=32.1875, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=28.6135693215339, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24158427, Length=341, Percent_Identity=26.3929618768328, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33606; Mature: 33606

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGGPVRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFASGRASNLEHLVGNPAHVFVEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCEEEEEEE
DIVTADLEAILDEHRPEVVFHLAAQIDVRHSVADPQFDASVNVIGTVRLAEAARRTGVRK
CCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
MVHTSSGGSIYGTPPTYPTPETVPTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPAN
HHEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VYGPRQDPHGEAGVVAIFAQALQSGKPTKVFGDGTNTRDYVFVDDVVDAFVKASGDAGGG
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHHHHCCCCCCCC
QRFNIGTGVETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAARVLGWQPKV
CEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GLQQGVARTVEYFRNQHN
CHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYGGPVRALVTGAAGFIGSTLVDRLLADGHTVVGLDNFASGRASNLEHLVGNPAHVFVEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCEEEEEEE
DIVTADLEAILDEHRPEVVFHLAAQIDVRHSVADPQFDASVNVIGTVRLAEAARRTGVRK
CCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
MVHTSSGGSIYGTPPTYPTPETVPTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPAN
HHEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VYGPRQDPHGEAGVVAIFAQALQSGKPTKVFGDGTNTRDYVFVDDVVDAFVKASGDAGGG
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEHHHHHHHHHHCCCCCCCC
QRFNIGTGVETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAARVLGWQPKV
CEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GLQQGVARTVEYFRNQHN
CHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]