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The map label for this gene is pheA

Identifier: 41406291

GI number: 41406291

Start: 198432

End: 199379

Strand: Direct

Name: pheA

Synonym: MAP0193

Alternate gene names: 41406291

Gene position: 198432-199379 (Clockwise)

Preceding gene: 41406288

Following gene: 41406292

Centisome position: 4.11

GC content: 75.53

Gene sequence:

>948_bases
GTGGCCCGCATCGCTTACCTCGGTCCGGAAGGGACCTTCACCGAGGCGGCGCTGCGGCAGATCACCGCCGCCGGCCTGGT
CCCCGGACAGGGGGCGGACGGTGTGCGGCCCACGCCGGTCGACGGCACGCCCGCGGCGCTGGACGCGGTGCGCGACGGCG
CCGCCGACTACGCGTGCGTGCCGATCGAGAACTCCATCGACGGCTCGGTGACGCCCACCCTGGACAGCCTCGCGATCGGC
TCGCCGCTGCAGGTGTTCGCGGAGACGACGCTGGACGTGGCGTTCAGCATCGTGGTCAAGCCGGGACTGTCCGCCGCCGA
CGTGCGGACCCTGGCAGCCATCGGGGTGGCCGCCGCCCAGGTGCGCCAGTGGGTGGCCGCCAACCTGGCCGGCGCGCAGC
TGCGCCCGGCCTATTCCAACGCCGACGCCGCCCAGCAGGTGGCCGAGGGGCGCGCCGACGCCGCGGTGACCTCCCCGCTG
GCCGCCGCCCGCTGGGGGTTGGACACCCTGGCCGACGGCGTGGTCGACGAACCCAACGCCCGCACCCGCTTCGTCCTGGT
CGGGCCGCCCGCGCCGCCGCCGGCCCGCACCGGCGCCGACCGGACCTCGGTGGTGCTGCGCATCGACAACGCGCCGGGCG
CCCTGCTGGCCGCGCTCGCGGAGTTCGGCATCCGCGGCATCGACCTGACCCGCATCGAATCCCGGCCCACCAGAACGGGT
TTGGGCATCTACCGGTTCTTCGCCGATTGCGTGGGCCACATCGACGACGAACCCGTCGCCGAGGCGCTCAAGGCGCTGCA
CCGCCGCTGTGCCGACGTGCGCTACCTGGGTTCGTGGCCCACCGGCACCCCCGCGGGGGCGCTGCCGCCGTCGACCGAGG
AAGCGGTGCGCTGGCTGGCGGCGGTGCGGGACGGCAAACCCGAACCCCCCGGGGAGTCGCGGCGGTGA

Upstream 100 bases:

>100_bases
GCGGTAACACGATTCTCCTTTGTTTAGGTAAGCCTAAGTTAACTTACCGCGTGTGGCGTGGCAAGAGTCTTCCCGCCGGC
ACGCCGCTAGGGTTGGGTCC

Downstream 100 bases:

>100_bases
GCGGCCGGTTGATCCTGGTGCGGCACGGCCAGTCGTACGGAAACGTCGAGCGCCGCCTCGACACCCGGCCGCCCGGCGCC
GAGCTCACGCCGCTGGGCCG

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MARIAYLGPEGTFTEAALRQITAAGLVPGQGADGVRPTPVDGTPAALDAVRDGAADYACVPIENSIDGSVTPTLDSLAIG
SPLQVFAETTLDVAFSIVVKPGLSAADVRTLAAIGVAAAQVRQWVAANLAGAQLRPAYSNADAAQQVAEGRADAAVTSPL
AAARWGLDTLADGVVDEPNARTRFVLVGPPAPPPARTGADRTSVVLRIDNAPGALLAALAEFGIRGIDLTRIESRPTRTG
LGIYRFFADCVGHIDDEPVAEALKALHRRCADVRYLGSWPTGTPAGALPPSTEEAVRWLAAVRDGKPEPPGESRR

Sequences:

>Translated_315_residues
MARIAYLGPEGTFTEAALRQITAAGLVPGQGADGVRPTPVDGTPAALDAVRDGAADYACVPIENSIDGSVTPTLDSLAIG
SPLQVFAETTLDVAFSIVVKPGLSAADVRTLAAIGVAAAQVRQWVAANLAGAQLRPAYSNADAAQQVAEGRADAAVTSPL
AAARWGLDTLADGVVDEPNARTRFVLVGPPAPPPARTGADRTSVVLRIDNAPGALLAALAEFGIRGIDLTRIESRPTRTG
LGIYRFFADCVGHIDDEPVAEALKALHRRCADVRYLGSWPTGTPAGALPPSTEEAVRWLAAVRDGKPEPPGESRR
>Mature_314_residues
ARIAYLGPEGTFTEAALRQITAAGLVPGQGADGVRPTPVDGTPAALDAVRDGAADYACVPIENSIDGSVTPTLDSLAIGS
PLQVFAETTLDVAFSIVVKPGLSAADVRTLAAIGVAAAQVRQWVAANLAGAQLRPAYSNADAAQQVAEGRADAAVTSPLA
AARWGLDTLADGVVDEPNARTRFVLVGPPAPPPARTGADRTSVVLRIDNAPGALLAALAEFGIRGIDLTRIESRPTRTGL
GIYRFFADCVGHIDDEPVAEALKALHRRCADVRYLGSWPTGTPAGALPPSTEEAVRWLAAVRDGKPEPPGESRR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain

Homologues:

Organism=Escherichia coli, GI1788951, Length=282, Percent_Identity=24.468085106383, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHEA_MYCA1 (A0Q994)

Other databases:

- EMBL:   CP000479
- RefSeq:   YP_879482.1
- ProteinModelPortal:   A0Q994
- SMR:   A0Q994
- STRING:   A0Q994
- EnsemblBacteria:   EBMYCT00000012987
- GeneID:   4527988
- GenomeReviews:   CP000479_GR
- KEGG:   mav:MAV_0188
- TIGR:   MAV_0188
- eggNOG:   COG0077
- GeneTree:   EBGT00050000015705
- HOGENOM:   HBG693866
- OMA:   CRKWLDA
- ProtClustDB:   PRK11898
- BioCyc:   MAVI243243:MAV_0188-MONOMER
- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528

Pfam domain/function: PF01842 ACT; PF00800 PDT

EC number: =4.2.1.51

Molecular weight: Translated: 32562; Mature: 32431

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00857 PREPHENATE_DEHYDR_1; PS00858 PREPHENATE_DEHYDR_2; PS51171 PREPHENATE_DEHYDR_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIAYLGPEGTFTEAALRQITAAGLVPGQGADGVRPTPVDGTPAALDAVRDGAADYACV
CCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEE
PIENSIDGSVTPTLDSLAIGSPLQVFAETTLDVAFSIVVKPGLSAADVRTLAAIGVAAAQ
ECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHH
VRQWVAANLAGAQLRPAYSNADAAQQVAEGRADAAVTSPLAAARWGLDTLADGVVDEPNA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCHHHHHHHCHHHHHCCCCCCCCC
RTRFVLVGPPAPPPARTGADRTSVVLRIDNAPGALLAALAEFGIRGIDLTRIESRPTRTG
CEEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCH
LGIYRFFADCVGHIDDEPVAEALKALHRRCADVRYLGSWPTGTPAGALPPSTEEAVRWLA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHHH
AVRDGKPEPPGESRR
HHHCCCCCCCCCCCC
>Mature Secondary Structure 
ARIAYLGPEGTFTEAALRQITAAGLVPGQGADGVRPTPVDGTPAALDAVRDGAADYACV
CEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEE
PIENSIDGSVTPTLDSLAIGSPLQVFAETTLDVAFSIVVKPGLSAADVRTLAAIGVAAAQ
ECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHH
VRQWVAANLAGAQLRPAYSNADAAQQVAEGRADAAVTSPLAAARWGLDTLADGVVDEPNA
HHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCHHHHHHHCHHHHHCCCCCCCCC
RTRFVLVGPPAPPPARTGADRTSVVLRIDNAPGALLAALAEFGIRGIDLTRIESRPTRTG
CEEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCH
LGIYRFFADCVGHIDDEPVAEALKALHRRCADVRYLGSWPTGTPAGALPPSTEEAVRWLA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCHHHHHHHHH
AVRDGKPEPPGESRR
HHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA