BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

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The map label for this gene is fabG [H]

Identifier: 41406177

GI number: 41406177

Start: 88710

End: 89450

Strand: Direct

Name: fabG [H]

Synonym: MAP0079

Alternate gene names: 41406177

Gene position: 88710-89450 (Clockwise)

Preceding gene: 41406176

Following gene: 41406179

Centisome position: 1.84

GC content: 68.02

Gene sequence:

>741_bases
ATGGCTGCACTGCAGGACAAGGTGGCGTTGGTGACCGGGGCGTCGTCGGGACTGGGCGCCGAAACCGCCAAACTGTTCTC
GAGCCAGGGCGCAACGGTTTTCGGCATCGGCCGCGACACCGTCCGCCTGGCCGAGGTGTTTGCCGGCATCGAACGCGGCG
GATTCGCGTCGGTGGACATCGCCTCACCGCAGGCCTGCACCGAGGCGGTCGCGCAGTGCGTGCGTGATTTCGGCGGACTG
GACGTGCTCGTCAACGTCGCCGGGATACACCGGATGCGCCGGACGGAATCGATGACCGACGAGGACTGGGAGCACGACCT
CGCGGTGAACCTGAACGGGCCGTTCTTCCTGTGCAGGGCGGCGCTGCCGGAGCTGCTGGAACGCGGCGGCAACATCGTCA
ACGTCAGCTCCATCGCCGGCGTCGAGGGACAGGCGTATTCGGCCGGCTACTGCGCGGCCAAGCATGGATTGATCGGTCTA
ACCCGCGCGCTGGCAGTGGAATACACCGCGGACCGGCTGCGCGTCAATGCGGTATGCCCGGGTGGCATGCTCACCCCGCA
GATCGAACGGTTCAGCGCGCCGGACGATCCGAACTACGACCTGATCCTGCGCACCGCCGCACCGCGCGGCATGATGCGAC
CGCTCGACGTCGCGAATGTGATCGCGTTCCTCGCCAGCGACGCGGCCGCTGCCGTGCACGGCGCCGTGTATCGGGTGGAC
AACGGCAAGGGCGCCGGCTGA

Upstream 100 bases:

>100_bases
CGCGCCGCGACCCACGCATCGAGACTGGTTGCACCGCTCGGTATTTTGCGTGCGGGCGTAACGCGGATCCGGTGCTACTA
GATAAGAGGAACACAACGAG

Downstream 100 bases:

>100_bases
CGGGCCCGACGCCGGCATCGTGCGTGCGCTACCAGAGCAGCGTGTCGAACATCAGCGCCGTGCCGGCGGCGGTGAACGCC
TGATACAGCGGCTCCATGCG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MAALQDKVALVTGASSGLGAETAKLFSSQGATVFGIGRDTVRLAEVFAGIERGGFASVDIASPQACTEAVAQCVRDFGGL
DVLVNVAGIHRMRRTESMTDEDWEHDLAVNLNGPFFLCRAALPELLERGGNIVNVSSIAGVEGQAYSAGYCAAKHGLIGL
TRALAVEYTADRLRVNAVCPGGMLTPQIERFSAPDDPNYDLILRTAAPRGMMRPLDVANVIAFLASDAAAAVHGAVYRVD
NGKGAG

Sequences:

>Translated_246_residues
MAALQDKVALVTGASSGLGAETAKLFSSQGATVFGIGRDTVRLAEVFAGIERGGFASVDIASPQACTEAVAQCVRDFGGL
DVLVNVAGIHRMRRTESMTDEDWEHDLAVNLNGPFFLCRAALPELLERGGNIVNVSSIAGVEGQAYSAGYCAAKHGLIGL
TRALAVEYTADRLRVNAVCPGGMLTPQIERFSAPDDPNYDLILRTAAPRGMMRPLDVANVIAFLASDAAAAVHGAVYRVD
NGKGAG
>Mature_245_residues
AALQDKVALVTGASSGLGAETAKLFSSQGATVFGIGRDTVRLAEVFAGIERGGFASVDIASPQACTEAVAQCVRDFGGLD
VLVNVAGIHRMRRTESMTDEDWEHDLAVNLNGPFFLCRAALPELLERGGNIVNVSSIAGVEGQAYSAGYCAAKHGLIGLT
RALAVEYTADRLRVNAVCPGGMLTPQIERFSAPDDPNYDLILRTAAPRGMMRPLDVANVIAFLASDAAAAVHGAVYRVDN
GKGAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=33.7254901960784, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=28.9795918367347, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI31542939, Length=256, Percent_Identity=30.859375, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=32.6530612244898, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=30, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI59889578, Length=178, Percent_Identity=34.8314606741573, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4504505, Length=185, Percent_Identity=35.6756756756757, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=28.4584980237154, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=29.9595141700405, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=30.5439330543933, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=33.1658291457286, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=31.1224489795918, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=29.9212598425197, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI33667109, Length=183, Percent_Identity=32.2404371584699, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=29.2817679558011, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=29.3877551020408, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=32.9411764705882, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI210032110, Length=182, Percent_Identity=27.4725274725275, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI157739938, Length=237, Percent_Identity=25.7383966244726, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI83715985, Length=179, Percent_Identity=33.5195530726257, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=24.1935483870968, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=25.7261410788382, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32455239, Length=191, Percent_Identity=32.4607329842932, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI5031765, Length=191, Percent_Identity=32.4607329842932, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4503301, Length=189, Percent_Identity=24.3386243386243, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=27.4611398963731, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.5238095238095, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=34.156378600823, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=30.7377049180328, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=32.6771653543307, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=29.3172690763052, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787526, Length=254, Percent_Identity=30.3149606299213, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=27.8225806451613, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=27.843137254902, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=29.6, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=28.2786885245902, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787820, Length=224, Percent_Identity=28.125, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=32.6771653543307, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=28.957528957529, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=35.7429718875502, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=35.4838709677419, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI193204405, Length=245, Percent_Identity=34.2857142857143, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=243, Percent_Identity=33.7448559670782, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17562908, Length=237, Percent_Identity=33.7552742616034, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560332, Length=244, Percent_Identity=33.1967213114754, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=32.7935222672065, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559104, Length=243, Percent_Identity=32.0987654320988, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=31.8007662835249, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=30.5220883534137, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560220, Length=243, Percent_Identity=32.5102880658436, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=241, Percent_Identity=34.0248962655602, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=250, Percent_Identity=32.4, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=244, Percent_Identity=31.5573770491803, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=28.2258064516129, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538486, Length=243, Percent_Identity=30.8641975308642, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=242, Percent_Identity=31.404958677686, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=242, Percent_Identity=28.099173553719, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=242, Percent_Identity=31.8181818181818, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=245, Percent_Identity=31.4285714285714, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=27.4193548387097, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=29.045643153527, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=222, Percent_Identity=30.1801801801802, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=242, Percent_Identity=30.5785123966942, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=187, Percent_Identity=31.0160427807487, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=32.8205128205128, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=242, Percent_Identity=29.7520661157025, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=246, Percent_Identity=32.1138211382114, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=183, Percent_Identity=32.2404371584699, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=183, Percent_Identity=32.2404371584699, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=186, Percent_Identity=28.494623655914, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=25.8964143426295, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=25.8964143426295, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=33.6842105263158, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320089, Length=207, Percent_Identity=28.5024154589372, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=210, Percent_Identity=28.0952380952381, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=25.8064516129032, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=36.1788617886179, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.5528455284553, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=35.6275303643725, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=34.251968503937, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=33.4645669291339, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24643142, Length=185, Percent_Identity=35.6756756756757, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI18859837, Length=186, Percent_Identity=34.9462365591398, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=27.0916334661355, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=27.3858921161826, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644337, Length=246, Percent_Identity=34.9593495934959, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641388, Length=239, Percent_Identity=29.7071129707113, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665247, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=30.2083333333333, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648693, Length=239, Percent_Identity=28.4518828451883, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355889, Length=239, Percent_Identity=28.4518828451883, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364494, Length=203, Percent_Identity=28.0788177339901, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281364892, Length=184, Percent_Identity=28.804347826087, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28571387, Length=150, Percent_Identity=32, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=29.3413173652695, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25680; Mature: 25549

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALQDKVALVTGASSGLGAETAKLFSSQGATVFGIGRDTVRLAEVFAGIERGGFASVDI
CCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEC
ASPQACTEAVAQCVRDFGGLDVLVNVAGIHRMRRTESMTDEDWEHDLAVNLNGPFFLCRA
CCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHH
ALPELLERGGNIVNVSSIAGVEGQAYSAGYCAAKHGLIGLTRALAVEYTADRLRVNAVCP
HHHHHHHCCCCEEEEHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHEECHHHEEEEEECC
GGMLTPQIERFSAPDDPNYDLILRTAAPRGMMRPLDVANVIAFLASDAAAAVHGAVYRVD
CCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHCEEEEEC
NGKGAG
CCCCCC
>Mature Secondary Structure 
AALQDKVALVTGASSGLGAETAKLFSSQGATVFGIGRDTVRLAEVFAGIERGGFASVDI
CCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEC
ASPQACTEAVAQCVRDFGGLDVLVNVAGIHRMRRTESMTDEDWEHDLAVNLNGPFFLCRA
CCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHH
ALPELLERGGNIVNVSSIAGVEGQAYSAGYCAAKHGLIGLTRALAVEYTADRLRVNAVCP
HHHHHHHCCCCEEEEHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHEECHHHEEEEEECC
GGMLTPQIERFSAPDDPNYDLILRTAAPRGMMRPLDVANVIAFLASDAAAAVHGAVYRVD
CCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHCEEEEEC
NGKGAG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]