Click here to switch to the map view.

The map label for this gene is fnr [H]

Identifier: 39998510

GI number: 39998510

Start: 3766220

End: 3766945

Strand: Reverse

Name: fnr [H]

Synonym: GSU3421

Alternate gene names: 39998510

Gene position: 3766945-3766220 (Counterclockwise)

Preceding gene: 39998511

Following gene: 39998508

Centisome position: 98.76

GC content: 63.5

Gene sequence:

>726_bases
ATGCGCGGTCGACCGGGACTGAAAGGACTTTTCATGGACATCAGGGACATCCTCAGGAAATCGCTTCTCTTTTCCGGCCT
GGACGAGAACCACCTGGCCGAAGTGGCGGCCATTGCCGCCCGCCGCCCCTTTGCCCGGGGAGAAACCGTCTTTGCCGAAG
GGGAGCCGGCAAACGGCTTTTACCTCCTGGCCCAGGGGAGCATGAAGCTCTGCAAGGTCTCGCCCGACGGCAAGGAGAAG
GTCCTCCACTTTGTTCATCCCGGCGAAACCTTTGCCGAGGCTGCTTTCTTCGGCGACGGCAAGTACCCCGCCGAGGCCCG
GGCCGTGGAGAAGGGGGAGGCGATCTTCTTCCCGCGCGAGGGCTTCATGGGTCTGCTTGAGCGCAATCCGCGCTTCTCCC
TGAACCTGATCGTGTCGCTGTCACTGATGCTTCGCCGCTTTGCCCGGCAGATCGAGGAACTCACCTTCGCGGAGGTGCCG
GCGCGCCTGGCCGCCCACCTGGTAGAGTTGGCCGAGCGCAAGTCCACCTCGTTCCAGGGAACGACCTACCTGGATCTGGA
TATGAAAAAGGGGGAACTGGCGTCACGCCTGGGCACGGTGAGCGAGACCCTGTCCCGTTCGTTCCGCAAGCTGAAGGAGG
AGGGGCTCATCGAGGTGGACGGGAGCCGCGTGGTGATCTTCGACATGGAAAAACTGAAGGCCGCTGCCGGGAGGCGCCCG
GCCTGA

Upstream 100 bases:

>100_bases
CAATCGCCCGGGCCCTGGGCATCATCGAATCACCCGACGTCCAGTCGGGCATGGAGCACCTGTTCCGCCTCATGGTGAGA
CAGACCCTCGGTGCCCGGGG

Downstream 100 bases:

>100_bases
CCTGCGCCGCCGCATCCCTGTTGTGCGATCCGTTGACAACCTCGCGGGATCGCCGCAGGGGATACGGGGCGGCTACTGCT
CCGCCGGTACTCGCTTCCAG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRGRPGLKGLFMDIRDILRKSLLFSGLDENHLAEVAAIAARRPFARGETVFAEGEPANGFYLLAQGSMKLCKVSPDGKEK
VLHFVHPGETFAEAAFFGDGKYPAEARAVEKGEAIFFPREGFMGLLERNPRFSLNLIVSLSLMLRRFARQIEELTFAEVP
ARLAAHLVELAERKSTSFQGTTYLDLDMKKGELASRLGTVSETLSRSFRKLKEEGLIEVDGSRVVIFDMEKLKAAAGRRP
A

Sequences:

>Translated_241_residues
MRGRPGLKGLFMDIRDILRKSLLFSGLDENHLAEVAAIAARRPFARGETVFAEGEPANGFYLLAQGSMKLCKVSPDGKEK
VLHFVHPGETFAEAAFFGDGKYPAEARAVEKGEAIFFPREGFMGLLERNPRFSLNLIVSLSLMLRRFARQIEELTFAEVP
ARLAAHLVELAERKSTSFQGTTYLDLDMKKGELASRLGTVSETLSRSFRKLKEEGLIEVDGSRVVIFDMEKLKAAAGRRP
A
>Mature_241_residues
MRGRPGLKGLFMDIRDILRKSLLFSGLDENHLAEVAAIAARRPFARGETVFAEGEPANGFYLLAQGSMKLCKVSPDGKEK
VLHFVHPGETFAEAAFFGDGKYPAEARAVEKGEAIFFPREGFMGLLERNPRFSLNLIVSLSLMLRRFARQIEELTFAEVP
ARLAAHLVELAERKSTSFQGTTYLDLDMKKGELASRLGTVSETLSRSFRKLKEEGLIEVDGSRVVIFDMEKLKAAAGRRP
A

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=213, Percent_Identity=24.8826291079812, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789756, Length=180, Percent_Identity=23.8888888888889, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26766; Mature: 26766

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGRPGLKGLFMDIRDILRKSLLFSGLDENHLAEVAAIAARRPFARGETVFAEGEPANGF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCE
YLLAQGSMKLCKVSPDGKEKVLHFVHPGETFAEAAFFGDGKYPAEARAVEKGEAIFFPRE
EEEEECCEEEEEECCCCHHHEEEEECCCHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCH
GFMGLLERNPRFSLNLIVSLSLMLRRFARQIEELTFAEVPARLAAHLVELAERKSTSFQG
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TTYLDLDMKKGELASRLGTVSETLSRSFRKLKEEGLIEVDGSRVVIFDMEKLKAAAGRRP
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHHHHCCCCC
A
C
>Mature Secondary Structure
MRGRPGLKGLFMDIRDILRKSLLFSGLDENHLAEVAAIAARRPFARGETVFAEGEPANGF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCE
YLLAQGSMKLCKVSPDGKEKVLHFVHPGETFAEAAFFGDGKYPAEARAVEKGEAIFFPRE
EEEEECCEEEEEECCCCHHHEEEEECCCHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCH
GFMGLLERNPRFSLNLIVSLSLMLRRFARQIEELTFAEVPARLAAHLVELAERKSTSFQG
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TTYLDLDMKKGELASRLGTVSETLSRSFRKLKEEGLIEVDGSRVVIFDMEKLKAAAGRRP
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHHHHCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]