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The map label for this gene is yrvM [H]

Identifier: 39998377

GI number: 39998377

Start: 3607503

End: 3608270

Strand: Direct

Name: yrvM [H]

Synonym: GSU3288

Alternate gene names: 39998377

Gene position: 3607503-3608270 (Clockwise)

Preceding gene: 39998376

Following gene: 39998378

Centisome position: 94.58

GC content: 63.8

Gene sequence:

>768_bases
ATGTCCCTTCACCGTTTTTCACGCACCGAGATCCTGATCGGCCCCGAAGGACTTCAGCGGCTGCACGGCTCGACTGTGGC
CGTGTTCGGCCTCGGCGGAGTCGGCAGCTTCGCGGCAGAGGCCCTCTGCCGCGCCGGGGTCGGCCGGCTGGTCCTCGTCG
ATTTCGACGATATCTGCCTCACCAACGTCAACCGGCAGCTCCACGCCCTGGACGGGACCGTGGGGAGGGCCAAGGTGCAG
GTCATGGCCGAACGCCTCCGCCTCATCAATCCCCAAGCGGACATCGTCCCGCACAAGGACTTCTACGAGGCGGCGAACAG
CGACTTCCTCCTCTCGGGGGGTCATGACTACGTGGTGGACGCCATTGACCACATCACGAGCAAGCTCCACCTGATCAGAA
GCTGCAAGGAGCGGGGGCTGCCCATCGTCTCAAGCATGGGGGCCGCCAACAAGCTTGACCCGGCTCGGATTCGCGTGGCT
GACATCGCCCAGACGAGCACCTGCCGCATGGCCAAGGTGGTGCGAAAGCTCCTCCGCAAGCAGGGGATCAAAAACGGGGT
GAAGGTGGTCTACTCCACCGAAGAGTACCGTGAACAGGCTATGCCTGATGCCGGGTGCCGGTCCGACTGCATCTGCCCCA
ACAAAGAGGAGCAGCGCTTCTCCTGCGAGCACCGCCGGACGATCCTCGGCAGCATTTCCTTCATTCCCAGCATATTCGGC
CTCACCATGGCCGGCGTCGTGGTGAACGACCTGCTGGAGCCCCGTTGA

Upstream 100 bases:

>100_bases
GACCGTCCGGGAACTCGCCGCCCAGACAACCCGAAACGCCCTCAGGCTCTTCCGCCGGATCGGTACAATCTAACCAATTG
CCCTGGCAGCGAGGTATCCC

Downstream 100 bases:

>100_bases
AAATTGCGTTGACCGGTTGAACGGCGCACAAGTGCCGCTATACTGTGTTTACACAATCGATATGATGGGATGAAAGGAGG
AATACTTCATGGGTAAGGAA

Product: thiF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSLHRFSRTEILIGPEGLQRLHGSTVAVFGLGGVGSFAAEALCRAGVGRLVLVDFDDICLTNVNRQLHALDGTVGRAKVQ
VMAERLRLINPQADIVPHKDFYEAANSDFLLSGGHDYVVDAIDHITSKLHLIRSCKERGLPIVSSMGAANKLDPARIRVA
DIAQTSTCRMAKVVRKLLRKQGIKNGVKVVYSTEEYREQAMPDAGCRSDCICPNKEEQRFSCEHRRTILGSISFIPSIFG
LTMAGVVVNDLLEPR

Sequences:

>Translated_255_residues
MSLHRFSRTEILIGPEGLQRLHGSTVAVFGLGGVGSFAAEALCRAGVGRLVLVDFDDICLTNVNRQLHALDGTVGRAKVQ
VMAERLRLINPQADIVPHKDFYEAANSDFLLSGGHDYVVDAIDHITSKLHLIRSCKERGLPIVSSMGAANKLDPARIRVA
DIAQTSTCRMAKVVRKLLRKQGIKNGVKVVYSTEEYREQAMPDAGCRSDCICPNKEEQRFSCEHRRTILGSISFIPSIFG
LTMAGVVVNDLLEPR
>Mature_254_residues
SLHRFSRTEILIGPEGLQRLHGSTVAVFGLGGVGSFAAEALCRAGVGRLVLVDFDDICLTNVNRQLHALDGTVGRAKVQV
MAERLRLINPQADIVPHKDFYEAANSDFLLSGGHDYVVDAIDHITSKLHLIRSCKERGLPIVSSMGAANKLDPARIRVAD
IAQTSTCRMAKVVRKLLRKQGIKNGVKVVYSTEEYREQAMPDAGCRSDCICPNKEEQRFSCEHRRTILGSISFIPSIFGL
TMAGVVVNDLLEPR

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=143, Percent_Identity=33.5664335664336, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789177, Length=198, Percent_Identity=42.9292929292929, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787048, Length=151, Percent_Identity=37.0860927152318, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87082356, Length=144, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540406, Length=151, Percent_Identity=29.1390728476821, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321790, Length=257, Percent_Identity=29.1828793774319, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6322825, Length=256, Percent_Identity=32.8125, Blast_Score=123, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24582879, Length=151, Percent_Identity=33.7748344370861, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27983; Mature: 27852

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLHRFSRTEILIGPEGLQRLHGSTVAVFGLGGVGSFAAEALCRAGVGRLVLVDFDDICL
CCCCCCCCCEEEECHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHH
TNVNRQLHALDGTVGRAKVQVMAERLRLINPQADIVPHKDFYEAANSDFLLSGGHDYVVD
HCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEEEECCCHHHHH
AIDHITSKLHLIRSCKERGLPIVSSMGAANKLDPARIRVADIAQTSTCRMAKVVRKLLRK
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHEEHHHHHCCHHHHHHHHHHHHHHH
QGIKNGVKVVYSTEEYREQAMPDAGCRSDCICPNKEEQRFSCEHRRTILGSISFIPSIFG
CCCCCCCEEEECCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTMAGVVVNDLLEPR
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLHRFSRTEILIGPEGLQRLHGSTVAVFGLGGVGSFAAEALCRAGVGRLVLVDFDDICL
CCCCCCCCEEEECHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHH
TNVNRQLHALDGTVGRAKVQVMAERLRLINPQADIVPHKDFYEAANSDFLLSGGHDYVVD
HCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEEEECCCHHHHH
AIDHITSKLHLIRSCKERGLPIVSSMGAANKLDPARIRVADIAQTSTCRMAKVVRKLLRK
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHEEHHHHHCCHHHHHHHHHHHHHHH
QGIKNGVKVVYSTEEYREQAMPDAGCRSDCICPNKEEQRFSCEHRRTILGSISFIPSIFG
CCCCCCCEEEECCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LTMAGVVVNDLLEPR
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]