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The map label for this gene is yabD [H]

Identifier: 39998376

GI number: 39998376

Start: 3606699

End: 3607475

Strand: Direct

Name: yabD [H]

Synonym: GSU3287

Alternate gene names: 39998376

Gene position: 3606699-3607475 (Clockwise)

Preceding gene: 39998375

Following gene: 39998377

Centisome position: 94.56

GC content: 66.28

Gene sequence:

>777_bases
ATGGAGCCCTTGCTCACCGATACCCATTGCCATCTGGACGCCCCGCCCTTACGAGGACGCCTCGACGAGGTCCTGGCTTC
GGCTCGCCATGCCGGCGTCGACCGGATCATCATCCCCGGCGTTGCCCCTGAGGGGTGGGATGAGATCGTCCACCTGTCCC
ACAGGTACCCCCGTGTCTTCGCTGCCTTCGGCATCCATCCCATGTACGCGGACCAGGCCGACGAGCAGACTCTCGCCCGG
CTTGCAGGACTGGCGCGCGATGCCGTTGCCGTCGGTGAAATCGGCCTCGACTACCTCTGCGCCGTTCCCCGCCCCGTTCA
ACAGGCAGCCTTCAGGGCCCAGCTCCGCGTGGCAGCGGAGGCCGGCGTTCCCGTTCTGATTCACTGCCGCCGCGCTTTTG
CCGACCTGCTTGCCATCCTGCGCGAAGAGAATATCTCCCGCATCGGCGGCGTGATGCACGCCTTTTCCGGGAGCGCCGAA
ATCATGGCAGAGTGCCTGAAACTCGGACTCCACATTGCCGTTTCAGGGGTGGTGACACGCCCAAACGCGGTCCGCCCGCC
GGAAATCGCACGCATCATCCCGGCGGACCGGCTACTCCTGGAAACCGATGCCCCCGACATGCCGCCCAATTCCCGGCTCG
GGTGCCCCAACGAGCCGGCATTCCTCCCGGAGACGGCCCAACGGCTGGCGGAGCTCCGGGGAACGACCGTCCGGGAACTC
GCCGCCCAGACAACCCGAAACGCCCTCAGGCTCTTCCGCCGGATCGGTACAATCTAA

Upstream 100 bases:

>100_bases
CATCGAGCCGCAGGAGTACACCCTGGCGGCTCTCACCGCTGAGATGGTCCGCCACTTCTCGGCACCCGCCTGAGCCACGT
TCACGGGGCAGTAGAGCTGA

Downstream 100 bases:

>100_bases
CCAATTGCCCTGGCAGCGAGGTATCCCATGTCCCTTCACCGTTTTTCACGCACCGAGATCCTGATCGGCCCCGAAGGACT
TCAGCGGCTGCACGGCTCGA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MEPLLTDTHCHLDAPPLRGRLDEVLASARHAGVDRIIIPGVAPEGWDEIVHLSHRYPRVFAAFGIHPMYADQADEQTLAR
LAGLARDAVAVGEIGLDYLCAVPRPVQQAAFRAQLRVAAEAGVPVLIHCRRAFADLLAILREENISRIGGVMHAFSGSAE
IMAECLKLGLHIAVSGVVTRPNAVRPPEIARIIPADRLLLETDAPDMPPNSRLGCPNEPAFLPETAQRLAELRGTTVREL
AAQTTRNALRLFRRIGTI

Sequences:

>Translated_258_residues
MEPLLTDTHCHLDAPPLRGRLDEVLASARHAGVDRIIIPGVAPEGWDEIVHLSHRYPRVFAAFGIHPMYADQADEQTLAR
LAGLARDAVAVGEIGLDYLCAVPRPVQQAAFRAQLRVAAEAGVPVLIHCRRAFADLLAILREENISRIGGVMHAFSGSAE
IMAECLKLGLHIAVSGVVTRPNAVRPPEIARIIPADRLLLETDAPDMPPNSRLGCPNEPAFLPETAQRLAELRGTTVREL
AAQTTRNALRLFRRIGTI
>Mature_258_residues
MEPLLTDTHCHLDAPPLRGRLDEVLASARHAGVDRIIIPGVAPEGWDEIVHLSHRYPRVFAAFGIHPMYADQADEQTLAR
LAGLARDAVAVGEIGLDYLCAVPRPVQQAAFRAQLRVAAEAGVPVLIHCRRAFADLLAILREENISRIGGVMHAFSGSAE
IMAECLKLGLHIAVSGVVTRPNAVRPPEIARIIPADRLLLETDAPDMPPNSRLGCPNEPAFLPETAQRLAELRGTTVREL
AAQTTRNALRLFRRIGTI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=264, Percent_Identity=26.5151515151515, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=27.3408239700375, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=27.3408239700375, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=26.8382352941176, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI225903439, Length=179, Percent_Identity=29.608938547486, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=26.4591439688716, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI225903424, Length=225, Percent_Identity=31.5555555555556, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=25.3275109170306, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1787342, Length=254, Percent_Identity=38.9763779527559, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI87082439, Length=253, Percent_Identity=36.7588932806324, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI48994985, Length=257, Percent_Identity=34.2412451361868, Blast_Score=128, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17559024, Length=279, Percent_Identity=29.3906810035842, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=27.9245283018868, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=215, Percent_Identity=28.8372093023256, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=31.095406360424, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI221330018, Length=198, Percent_Identity=31.8181818181818, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24586117, Length=198, Percent_Identity=31.8181818181818, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28072; Mature: 28072

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLLTDTHCHLDAPPLRGRLDEVLASARHAGVDRIIIPGVAPEGWDEIVHLSHRYPRVF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCHHHH
AAFGIHPMYADQADEQTLARLAGLARDAVAVGEIGLDYLCAVPRPVQQAAFRAQLRVAAE
HHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHH
AGVPVLIHCRRAFADLLAILREENISRIGGVMHAFSGSAEIMAECLKLGLHIAVSGVVTR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEC
PNAVRPPEIARIIPADRLLLETDAPDMPPNSRLGCPNEPAFLPETAQRLAELRGTTVREL
CCCCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHH
AAQTTRNALRLFRRIGTI
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEPLLTDTHCHLDAPPLRGRLDEVLASARHAGVDRIIIPGVAPEGWDEIVHLSHRYPRVF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCHHHH
AAFGIHPMYADQADEQTLARLAGLARDAVAVGEIGLDYLCAVPRPVQQAAFRAQLRVAAE
HHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHH
AGVPVLIHCRRAFADLLAILREENISRIGGVMHAFSGSAEIMAECLKLGLHIAVSGVVTR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEC
PNAVRPPEIARIIPADRLLLETDAPDMPPNSRLGCPNEPAFLPETAQRLAELRGTTVREL
CCCCCCCHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHH
AAQTTRNALRLFRRIGTI
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]