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The map label for this gene is mraY [H]

Identifier: 39998163

GI number: 39998163

Start: 3378645

End: 3379721

Strand: Reverse

Name: mraY [H]

Synonym: GSU3072

Alternate gene names: 39998163

Gene position: 3379721-3378645 (Counterclockwise)

Preceding gene: 39998164

Following gene: 39998162

Centisome position: 88.61

GC content: 58.96

Gene sequence:

>1077_bases
ATGCTGTATCATCTGCTCTATCCACTGGCCGCCGACTTTCGGATCTTCAACGTCTTCAAATATCTGACGTTCCGGACCAT
CTATGCCGTCATCACTGCCCTGGTGGTTTCGTTCATCCTGGGACCGTGGGTCATCCGAAAGCTGGAGGCGCTCCAGGCCC
GTCAGGTGATCCGAACCGATGGCCCCGAGTCGCACCTGAAAAAATCGGGAACCCCCACGATGGGGGGGATCCTCATCCTC
GCATCCATCGTCATTCCGACACTGCTCTGGGCCGATCTGACGAACCGGTACGTCTGGACGACACTTTTCGTGATCCTCGG
CTACGGCCTTATCGGCTTCACCGACGATTACAAAAAGGTGGTGGAAAAGGATACCAAGGGGCTCTCGCCTCGTCAGAAGA
TGTTCTGGCAGATGCTCATCGCGGGCGGAGCCGTCTGCTTCCTCGTCCTCGTCGCCGGCATGTCCACGGAGCTTTCGGTG
CCCTTCTTCAAGCGGCTGCACCCTGACCTTTCCTATCTCTATATTCCCTTCGGCATGCTGGTTGTCGTGGGGGCGAGCAA
TGCCGTGAACCTGACCGACGGTCTCGACGGCCTCGCTATCGGGCCGGTTGCCATCAATGCAGCCACGTTTCTGCTTTTTG
CCTACATTGCGGGGAATGCCAAACTTTCCAGTTATCTCCAGACTCCCTATGTGCCGGGAGCCGGTGAGCTGGCGGTCCTC
TGTGGCGCCATGGTGGGCGCCGGCATCGGGTTTCTCTGGTACAACGCCTATCCCGCCGAGGTCTTCATGGGAGACGTGGG
CTCGCTTTCTCTGGGGGGCGGGCTCGGCATCCTGGCGGTCATCACCAAGCAGGAGATGCTGCTGGTGATCGTGGGCGGCA
TTTTCGTGGTGGAGGCCCTGTCGGTCATCTTCCAGGTCGGGTCGTACAAGTACCGGGGCAAGCGGATCTTCCGGATGGCG
CCCATCCACCACCACTTCGAACTGAAAGGGGTGGCGGAGCCGAAGATCATCGTCAGGTTCTGGATCATCACCATCATTCT
TGCGCTAGTCGCCATTTCGACGCTGAAGCTGAGATAG

Upstream 100 bases:

>100_bases
TGATTCTGGTGAAGGGCTCCCGCGGCATGGCCATGGATCGGGTCGCCGAGGGAATCAGAGAGGCGTTCGCCGCCTCCGGC
GGCAAAGGGGGCCACGTCTA

Downstream 100 bases:

>100_bases
CATGGACCTCAAAGGAAAGAACATACTCGTTGTGGGCCTCGCCCGGACCGGCGTGGCGGTTGCCCGTTTCCTCGCGGCGC
AGGGCGCCCGGGTGACCGTG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLYHLLYPLAADFRIFNVFKYLTFRTIYAVITALVVSFILGPWVIRKLEALQARQVIRTDGPESHLKKSGTPTMGGILIL
ASIVIPTLLWADLTNRYVWTTLFVILGYGLIGFTDDYKKVVEKDTKGLSPRQKMFWQMLIAGGAVCFLVLVAGMSTELSV
PFFKRLHPDLSYLYIPFGMLVVVGASNAVNLTDGLDGLAIGPVAINAATFLLFAYIAGNAKLSSYLQTPYVPGAGELAVL
CGAMVGAGIGFLWYNAYPAEVFMGDVGSLSLGGGLGILAVITKQEMLLVIVGGIFVVEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKLR

Sequences:

>Translated_358_residues
MLYHLLYPLAADFRIFNVFKYLTFRTIYAVITALVVSFILGPWVIRKLEALQARQVIRTDGPESHLKKSGTPTMGGILIL
ASIVIPTLLWADLTNRYVWTTLFVILGYGLIGFTDDYKKVVEKDTKGLSPRQKMFWQMLIAGGAVCFLVLVAGMSTELSV
PFFKRLHPDLSYLYIPFGMLVVVGASNAVNLTDGLDGLAIGPVAINAATFLLFAYIAGNAKLSSYLQTPYVPGAGELAVL
CGAMVGAGIGFLWYNAYPAEVFMGDVGSLSLGGGLGILAVITKQEMLLVIVGGIFVVEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKLR
>Mature_358_residues
MLYHLLYPLAADFRIFNVFKYLTFRTIYAVITALVVSFILGPWVIRKLEALQARQVIRTDGPESHLKKSGTPTMGGILIL
ASIVIPTLLWADLTNRYVWTTLFVILGYGLIGFTDDYKKVVEKDTKGLSPRQKMFWQMLIAGGAVCFLVLVAGMSTELSV
PFFKRLHPDLSYLYIPFGMLVVVGASNAVNLTDGLDGLAIGPVAINAATFLLFAYIAGNAKLSSYLQTPYVPGAGELAVL
CGAMVGAGIGFLWYNAYPAEVFMGDVGSLSLGGGLGILAVITKQEMLLVIVGGIFVVEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=59.0027700831025, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39203; Mature: 39203

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYHLLYPLAADFRIFNVFKYLTFRTIYAVITALVVSFILGPWVIRKLEALQARQVIRTD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPESHLKKSGTPTMGGILILASIVIPTLLWADLTNRYVWTTLFVILGYGLIGFTDDYKKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHCCCHHHHHH
VEKDTKGLSPRQKMFWQMLIAGGAVCFLVLVAGMSTELSVPFFKRLHPDLSYLYIPFGML
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHH
VVVGASNAVNLTDGLDGLAIGPVAINAATFLLFAYIAGNAKLSSYLQTPYVPGAGELAVL
HEECCCCCEECCCCCCCCEECHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHH
CGAMVGAGIGFLWYNAYPAEVFMGDVGSLSLGGGLGILAVITKQEMLLVIVGGIFVVEAL
HHHHHHCCHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKLR
HHHHHHCCCEECCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYHLLYPLAADFRIFNVFKYLTFRTIYAVITALVVSFILGPWVIRKLEALQARQVIRTD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPESHLKKSGTPTMGGILILASIVIPTLLWADLTNRYVWTTLFVILGYGLIGFTDDYKKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHCCCHHHHHH
VEKDTKGLSPRQKMFWQMLIAGGAVCFLVLVAGMSTELSVPFFKRLHPDLSYLYIPFGML
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHH
VVVGASNAVNLTDGLDGLAIGPVAINAATFLLFAYIAGNAKLSSYLQTPYVPGAGELAVL
HEECCCCCEECCCCCCCCEECHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHH
CGAMVGAGIGFLWYNAYPAEVFMGDVGSLSLGGGLGILAVITKQEMLLVIVGGIFVVEAL
HHHHHHCCHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKLR
HHHHHHCCCEECCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA