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The map label for this gene is gpmB [H]

Identifier: 39998098

GI number: 39998098

Start: 3299819

End: 3300472

Strand: Reverse

Name: gpmB [H]

Synonym: GSU3007

Alternate gene names: 39998098

Gene position: 3300472-3299819 (Counterclockwise)

Preceding gene: 39998099

Following gene: 39998097

Centisome position: 86.53

GC content: 63.76

Gene sequence:

>654_bases
GTGAGGCTGCCCGAACAAACAACAGGGATATTTCCCTCTCTGGAACGGAACATGACACGCAAAACACGCATCTATCTCAT
CCGTCACGGCGAAGTGGAGGGGGCCGGCGTCCCCCGTTACAACGGACACAACGACGTGGGCCTCTCCGAGCGGGGTAAGG
CCCAGTACCTGGAACTCCGCAAGCGGTTCGACGGGGTTCGGATCGCCGCCTGCTACACCAGCGACCTTACCCGCTGCGTC
TGGGGTGCCGAGTCCCTGGCCGCCCACCTGAACGTTCAGCCGCAGCGCCACCCGGAACTGCGGGAAATCTGCATGGGCGA
ATGGGAGGCGAAGAGCTGGCAAGAGCTCCAGGACCGCTATCCCCACCAGTGGCAGGCACGGCTCAACGACCTGGAAGGCT
ACCGGGTGCCGGGGGGGGAAAACCTGCTGGACGTCCGGGCCCGGGTTATGCCCGCCGTCAATGCCATCGTTGAGCGGCAC
CGGGGGGAAGACGTCCTGGTGGTGGCCCACGGCGGCGTGAACCGGATCATCCTCCTGGAGGCCATCGGTGCACCCCTGGC
CAACCTCTTTTCCCTTGAGCAGACTTACTGCTGCATGAACATCATCGACTACTTCGAGGATGGGCGTGCGGTGGTGAAGC
TGGTGAACGGGTAG

Upstream 100 bases:

>100_bases
CTGGCCCTGCACCGGGGCTGACAGCCCCGTACGGAGACTGTCCTTCCATACTTCGATTCCTTGCCGGGAACACACAGGAT
GTAGAGGCAGGGGCTATGCC

Downstream 100 bases:

>100_bases
ACCATGAAATCGATCATCATCGCCGCCCCGCACAGTGGCTCCGGCAAGACAACCATCACCGTGGGCATCATGGAATGCTT
CAGGCGGCGCGGCCTCACCG

Product: phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MRLPEQTTGIFPSLERNMTRKTRIYLIRHGEVEGAGVPRYNGHNDVGLSERGKAQYLELRKRFDGVRIAACYTSDLTRCV
WGAESLAAHLNVQPQRHPELREICMGEWEAKSWQELQDRYPHQWQARLNDLEGYRVPGGENLLDVRARVMPAVNAIVERH
RGEDVLVVAHGGVNRIILLEAIGAPLANLFSLEQTYCCMNIIDYFEDGRAVVKLVNG

Sequences:

>Translated_217_residues
MRLPEQTTGIFPSLERNMTRKTRIYLIRHGEVEGAGVPRYNGHNDVGLSERGKAQYLELRKRFDGVRIAACYTSDLTRCV
WGAESLAAHLNVQPQRHPELREICMGEWEAKSWQELQDRYPHQWQARLNDLEGYRVPGGENLLDVRARVMPAVNAIVERH
RGEDVLVVAHGGVNRIILLEAIGAPLANLFSLEQTYCCMNIIDYFEDGRAVVKLVNG
>Mature_217_residues
MRLPEQTTGIFPSLERNMTRKTRIYLIRHGEVEGAGVPRYNGHNDVGLSERGKAQYLELRKRFDGVRIAACYTSDLTRCV
WGAESLAAHLNVQPQRHPELREICMGEWEAKSWQELQDRYPHQWQARLNDLEGYRVPGGENLLDVRARVMPAVNAIVERH
RGEDVLVVAHGGVNRIILLEAIGAPLANLFSLEQTYCCMNIIDYFEDGRAVVKLVNG

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI64762406, Length=181, Percent_Identity=34.8066298342541, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI64762445, Length=181, Percent_Identity=34.8066298342541, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI118582286, Length=158, Percent_Identity=36.7088607594937, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4758902, Length=157, Percent_Identity=35.6687898089172, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI224282149, Length=157, Percent_Identity=35.031847133758, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI4758900, Length=157, Percent_Identity=35.031847133758, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786857, Length=181, Percent_Identity=27.6243093922652, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790856, Length=184, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25145314, Length=173, Percent_Identity=31.7919075144509, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322306, Length=165, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 24679; Mature: 24679

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPEQTTGIFPSLERNMTRKTRIYLIRHGEVEGAGVPRYNGHNDVGLSERGKAQYLELR
CCCCCCCCCCCCHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
KRFDGVRIAACYTSDLTRCVWGAESLAAHLNVQPQRHPELREICMGEWEAKSWQELQDRY
HHCCCEEEEEEEHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCC
PHQWQARLNDLEGYRVPGGENLLDVRARVMPAVNAIVERHRGEDVLVVAHGGVNRIILLE
CHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEE
AIGAPLANLFSLEQTYCCMNIIDYFEDGRAVVKLVNG
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MRLPEQTTGIFPSLERNMTRKTRIYLIRHGEVEGAGVPRYNGHNDVGLSERGKAQYLELR
CCCCCCCCCCCCHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
KRFDGVRIAACYTSDLTRCVWGAESLAAHLNVQPQRHPELREICMGEWEAKSWQELQDRY
HHCCCEEEEEEEHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCC
PHQWQARLNDLEGYRVPGGENLLDVRARVMPAVNAIVERHRGEDVLVVAHGGVNRIILLE
CHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEE
AIGAPLANLFSLEQTYCCMNIIDYFEDGRAVVKLVNG
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA