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The map label for this gene is cobB [H]

Identifier: 39998097

GI number: 39998097

Start: 3298421

End: 3299815

Strand: Reverse

Name: cobB [H]

Synonym: GSU3006

Alternate gene names: 39998097

Gene position: 3299815-3298421 (Counterclockwise)

Preceding gene: 39998098

Following gene: 39998096

Centisome position: 86.52

GC content: 66.45

Gene sequence:

>1395_bases
ATGAAATCGATCATCATCGCCGCCCCGCACAGTGGCTCCGGCAAGACAACCATCACCGTGGGCATCATGGAATGCTTCAG
GCGGCGCGGCCTCACCGTGGCACCCTTCAAGGTGGGTCCGGACTTCATCGATCCGGGCTACCACCGGCTGGTGACGGGGT
TGCCCTCGGCCAACCTGGACGGCTGGATCTGTCCTCCCGAGTTTGTCCGGGCATCCTTTGCCCACCATGCCCTCAACGCC
GACATGGCCATCATCGAGGGAGTCATGGGGCTCTTCGACGGGTTCGGAGGGATCGCCGACGAGGGGAGTACGGCCCAGGT
GGCCCGGCTGACCGGTGCGCCGGTGATCCTGGTGGTGGATGCCCGTGGGCTGGCCAGGAGCGCCGCCGCCATCCTCAAGG
GGTTCGCCGAATTCGATCCCTCGGTGCGGGTGGCCGGGGTCATCTTCAATAACGTGGGCAGCGACAGTCACGAGCGAATT
CTGCGGGAGGCGGTGGGGCAGTCCCTGCCGGAGCTGAAGGTGTTCGGCTGTATCCCCCGGGACGACGGGCTTCACATCCC
TGCACGCCACCTGGGACTTCTCACGGCGGAGGAACATCCCCTGTCGGGCGAGTTCCTGGATCACCTGGTGGAGGTGATTC
GCGACCGGGTTGACCTGGGGCTGCTCTGGGGAGCGGCCAACCCCTTGGGCGCGCCGGTGCCCCGCGCCGAACCGATTCCC
TGCCAGACCCTGGGCGGTTCGGTCCGACTGGCAGTCGCCCGGGACGAAGCCTTTTGTTTCGTCTATGAGGACAACCTCTG
CCTGCTGCGCCGCGCCGGCGCCGAGATAGTCACCTTTTCCCCCCTGCGCGACGAGCGCCTGCCAGAGGATGTGGCCGGCG
TCTACCTGCCGGGCGGCTACCCCGAGGTCTTCGCCGATGCCCTGGCCGCCAACACCGGGATGAAGGAGTCTTTGGCCCGG
GCCGTGAACGAGGGGATGCCGGTTTACGCCGAATGCGGCGGTTTCATCTACCTTACGCGCGGGGTTACGGACAGCGCCGG
GGAGCCTGAATCGCTCCACGAGTTCGTAGGGATATTCCCCGTGACAACCCGGATGCTTCCCCGCCGCAAGGCCCTCGGCT
ATCGCGAGGTTGAACTGGCGGCGGATACCATCATCGGCCCCGCCGGCACCCTGGCCCGGGGGCACGAGTTCCACTACTCG
GAGATGGAAGAGATGCCCGCCGACGTGGAGCGTGCCTACCGGGTCCGCCGGGGCCCGGTTGACCTGGGGATGGAAGGATA
CCGTTACCGCAACTGTCTTGCCTCCTACGTCCACCTCCACTTCGGGAGCAACCCGGAGCTGGCCGCGGCGTTTGTGGCAC
GCTGCAGATCGTTCGTCACAAGGAGCCGTGTGTGA

Upstream 100 bases:

>100_bases
GGCCAACCTCTTTTCCCTTGAGCAGACTTACTGCTGCATGAACATCATCGACTACTTCGAGGATGGGCGTGCGGTGGTGA
AGCTGGTGAACGGGTAGACC

Downstream 100 bases:

>100_bases
AAACCCAGATCGAACAGGCCCGCGAGGGCATCATTACCCCTCAGATGGCGGCCGTGGCCGCGGAGGAGCACGTCTCCCCC
GAGTATGTCTGCCGGATGGT

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKSIIIAAPHSGSGKTTITVGIMECFRRRGLTVAPFKVGPDFIDPGYHRLVTGLPSANLDGWICPPEFVRASFAHHALNA
DMAIIEGVMGLFDGFGGIADEGSTAQVARLTGAPVILVVDARGLARSAAAILKGFAEFDPSVRVAGVIFNNVGSDSHERI
LREAVGQSLPELKVFGCIPRDDGLHIPARHLGLLTAEEHPLSGEFLDHLVEVIRDRVDLGLLWGAANPLGAPVPRAEPIP
CQTLGGSVRLAVARDEAFCFVYEDNLCLLRRAGAEIVTFSPLRDERLPEDVAGVYLPGGYPEVFADALAANTGMKESLAR
AVNEGMPVYAECGGFIYLTRGVTDSAGEPESLHEFVGIFPVTTRMLPRRKALGYREVELAADTIIGPAGTLARGHEFHYS
EMEEMPADVERAYRVRRGPVDLGMEGYRYRNCLASYVHLHFGSNPELAAAFVARCRSFVTRSRV

Sequences:

>Translated_464_residues
MKSIIIAAPHSGSGKTTITVGIMECFRRRGLTVAPFKVGPDFIDPGYHRLVTGLPSANLDGWICPPEFVRASFAHHALNA
DMAIIEGVMGLFDGFGGIADEGSTAQVARLTGAPVILVVDARGLARSAAAILKGFAEFDPSVRVAGVIFNNVGSDSHERI
LREAVGQSLPELKVFGCIPRDDGLHIPARHLGLLTAEEHPLSGEFLDHLVEVIRDRVDLGLLWGAANPLGAPVPRAEPIP
CQTLGGSVRLAVARDEAFCFVYEDNLCLLRRAGAEIVTFSPLRDERLPEDVAGVYLPGGYPEVFADALAANTGMKESLAR
AVNEGMPVYAECGGFIYLTRGVTDSAGEPESLHEFVGIFPVTTRMLPRRKALGYREVELAADTIIGPAGTLARGHEFHYS
EMEEMPADVERAYRVRRGPVDLGMEGYRYRNCLASYVHLHFGSNPELAAAFVARCRSFVTRSRV
>Mature_464_residues
MKSIIIAAPHSGSGKTTITVGIMECFRRRGLTVAPFKVGPDFIDPGYHRLVTGLPSANLDGWICPPEFVRASFAHHALNA
DMAIIEGVMGLFDGFGGIADEGSTAQVARLTGAPVILVVDARGLARSAAAILKGFAEFDPSVRVAGVIFNNVGSDSHERI
LREAVGQSLPELKVFGCIPRDDGLHIPARHLGLLTAEEHPLSGEFLDHLVEVIRDRVDLGLLWGAANPLGAPVPRAEPIP
CQTLGGSVRLAVARDEAFCFVYEDNLCLLRRAGAEIVTFSPLRDERLPEDVAGVYLPGGYPEVFADALAANTGMKESLAR
AVNEGMPVYAECGGFIYLTRGVTDSAGEPESLHEFVGIFPVTTRMLPRRKALGYREVELAADTIIGPAGTLARGHEFHYS
EMEEMPADVERAYRVRRGPVDLGMEGYRYRNCLASYVHLHFGSNPELAAAFVARCRSFVTRSRV

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 50147; Mature: 50147

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIIIAAPHSGSGKTTITVGIMECFRRRGLTVAPFKVGPDFIDPGYHRLVTGLPSANLD
CCCEEEECCCCCCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCC
GWICPPEFVRASFAHHALNADMAIIEGVMGLFDGFGGIADEGSTAQVARLTGAPVILVVD
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEC
ARGLARSAAAILKGFAEFDPSVRVAGVIFNNVGSDSHERILREAVGQSLPELKVFGCIPR
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCC
DDGLHIPARHLGLLTAEEHPLSGEFLDHLVEVIRDRVDLGLLWGAANPLGAPVPRAEPIP
CCCCCCCHHHHCEEECCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCC
CQTLGGSVRLAVARDEAFCFVYEDNLCLLRRAGAEIVTFSPLRDERLPEDVAGVYLPGGY
HHHCCCCEEEEEEECCEEEEEEECCEEEEECCCCCEEEECCCCCCCCCHHHCCEECCCCC
PEVFADALAANTGMKESLARAVNEGMPVYAECGGFIYLTRGVTDSAGEPESLHEFVGIFP
HHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHH
VTTRMLPRRKALGYREVELAADTIIGPAGTLARGHEFHYSEMEEMPADVERAYRVRRGPV
HHHHHCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCC
DLGMEGYRYRNCLASYVHLHFGSNPELAAAFVARCRSFVTRSRV
CCCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSIIIAAPHSGSGKTTITVGIMECFRRRGLTVAPFKVGPDFIDPGYHRLVTGLPSANLD
CCCEEEECCCCCCCCEEEEHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCC
GWICPPEFVRASFAHHALNADMAIIEGVMGLFDGFGGIADEGSTAQVARLTGAPVILVVD
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEC
ARGLARSAAAILKGFAEFDPSVRVAGVIFNNVGSDSHERILREAVGQSLPELKVFGCIPR
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCC
DDGLHIPARHLGLLTAEEHPLSGEFLDHLVEVIRDRVDLGLLWGAANPLGAPVPRAEPIP
CCCCCCCHHHHCEEECCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCC
CQTLGGSVRLAVARDEAFCFVYEDNLCLLRRAGAEIVTFSPLRDERLPEDVAGVYLPGGY
HHHCCCCEEEEEEECCEEEEEEECCEEEEECCCCCEEEECCCCCCCCCHHHCCEECCCCC
PEVFADALAANTGMKESLARAVNEGMPVYAECGGFIYLTRGVTDSAGEPESLHEFVGIFP
HHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHH
VTTRMLPRRKALGYREVELAADTIIGPAGTLARGHEFHYSEMEEMPADVERAYRVRRGPV
HHHHHCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCC
DLGMEGYRYRNCLASYVHLHFGSNPELAAAFVARCRSFVTRSRV
CCCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA