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The map label for this gene is relA [C]

Identifier: 39997537

GI number: 39997537

Start: 2675932

End: 2676954

Strand: Reverse

Name: relA [C]

Synonym: GSU2442

Alternate gene names: 39997537

Gene position: 2676954-2675932 (Counterclockwise)

Preceding gene: 39997538

Following gene: 39997536

Centisome position: 70.19

GC content: 37.24

Gene sequence:

>1023_bases
ATGAAATGGGTAACCTGTGATTACTCCAAGAAAGATGTTATGCGAGCTGGAGAGCAATTAATCAGCGAATCAGTTACTGA
TCAAGAGCTGTCAACAGCTATGGATGTTCTCTCAAGTTGGAGGGCAGCGCATGCATATCCAATGCATGCATTACTGATAT
TTCTCAGGACACAATCAAGTAAAATTGATGCAAATACTATCGTGGTACAGCGACTAAAAAGGACGCCATCGATACTTGAT
AAGTTATCTAGATTTCCTCAAATGAAGCTACATCGTATGCAAGATATCAGTGGATGTAGAGCAGTAGTTAACAATGTTAA
TATGGTTGAAAAATTATCTGACTCTATTACTAATAGTAGGACAAGGCACAAATTACATAAAAAAGATGATTATATACAAA
ATCCAAAGTTGTCAGGATATAGAGGCATACATCTAGTATATAAATATAAAGGTGGAAAGAAGGCGTACTCTGATTATTTT
GTAGAAATTCAGCTTAGATCAAAAATACAGCACGCATGGGCTACATCAGTCGAAATAGTGGACATATTCACACGACAAGC
GTTAAAAGCCAGTCATGGTAGTAAAGAATGGCTCGACTTTTTCATGTATGCCAGCGCTGAATTTGCAAAGCTTGAAAAAA
GGCCAATAGGTAACCACCTAGATGGAATAGACACCAAATTACATTTAAAAAAACTTGCTGATAGTCTGAGCGTTGTCAAT
AGACTAAATGCGTTTGCAGTCTCTACACAGTATGTTGCGACGAAGCAAGACAATAGAACTGACTATTTCTTACTAGAACT
AACAGATACTGCGCAAGCCATCATGGTAACCCAATATACGTCTGCTGATTTAGATAAAGCTACTAAAGCATACCTTGAAA
AAGAAAAAGCAGCAAAAAATGATTCTACTTATGATGTTGTATTGGTAGCAGCTGGATCAATGCATGCACTAAAAGCCGCT
TATCCTAACTACTTTGCAGATTCAAAGGCATTTCTTAATTACCTCGCAAAGGTACTGAGCTAA

Upstream 100 bases:

>100_bases
GCTTATCGCGAAGAGACGATCCAACACACGAATAGACCTGTTTCGCTTCGCTCCCAGGTCATTCGCACCACCGTTATCTC
TTTAACTAGGAGATCTTAAA

Downstream 100 bases:

>100_bases
CTCTCGAATCGACGTGAATCGGGTCGGACCAAGTCAACTTGCCGATATTTCAGCAAATACACCTCAATTCAGGAGGATTT
TTACCCGTAGAAGCGCATTT

Product: RelA/SpoT domain protein

Products: guanosine 3'-diphosphate 5'-triphosphate; AMP [C]

Alternate protein names: RelA/SpoT Domain-Containing Protein; RelA/SpoT; GTP Pyrophosphokinase; Conserved Domain Protein; Stringent Response Modulating PpGpp Metabolism Protein; Rela/Spot Domain Protein

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKWVTCDYSKKDVMRAGEQLISESVTDQELSTAMDVLSSWRAAHAYPMHALLIFLRTQSSKIDANTIVVQRLKRTPSILD
KLSRFPQMKLHRMQDISGCRAVVNNVNMVEKLSDSITNSRTRHKLHKKDDYIQNPKLSGYRGIHLVYKYKGGKKAYSDYF
VEIQLRSKIQHAWATSVEIVDIFTRQALKASHGSKEWLDFFMYASAEFAKLEKRPIGNHLDGIDTKLHLKKLADSLSVVN
RLNAFAVSTQYVATKQDNRTDYFLLELTDTAQAIMVTQYTSADLDKATKAYLEKEKAAKNDSTYDVVLVAAGSMHALKAA
YPNYFADSKAFLNYLAKVLS

Sequences:

>Translated_340_residues
MKWVTCDYSKKDVMRAGEQLISESVTDQELSTAMDVLSSWRAAHAYPMHALLIFLRTQSSKIDANTIVVQRLKRTPSILD
KLSRFPQMKLHRMQDISGCRAVVNNVNMVEKLSDSITNSRTRHKLHKKDDYIQNPKLSGYRGIHLVYKYKGGKKAYSDYF
VEIQLRSKIQHAWATSVEIVDIFTRQALKASHGSKEWLDFFMYASAEFAKLEKRPIGNHLDGIDTKLHLKKLADSLSVVN
RLNAFAVSTQYVATKQDNRTDYFLLELTDTAQAIMVTQYTSADLDKATKAYLEKEKAAKNDSTYDVVLVAAGSMHALKAA
YPNYFADSKAFLNYLAKVLS
>Mature_340_residues
MKWVTCDYSKKDVMRAGEQLISESVTDQELSTAMDVLSSWRAAHAYPMHALLIFLRTQSSKIDANTIVVQRLKRTPSILD
KLSRFPQMKLHRMQDISGCRAVVNNVNMVEKLSDSITNSRTRHKLHKKDDYIQNPKLSGYRGIHLVYKYKGGKKAYSDYF
VEIQLRSKIQHAWATSVEIVDIFTRQALKASHGSKEWLDFFMYASAEFAKLEKRPIGNHLDGIDTKLHLKKLADSLSVVN
RLNAFAVSTQYVATKQDNRTDYFLLELTDTAQAIMVTQYTSADLDKATKAYLEKEKAAKNDSTYDVVLVAAGSMHALKAA
YPNYFADSKAFLNYLAKVLS

Specific function: In Eubacteria Ppgpp (Guanosine 3'-Diphosphate 5-' Diphosphate) Is A Mediator Of The Stringent Response That Coordinates A Variety Of Cellular Activities In Response To Changes In Nutritional Abundance. This Enzyme Catalyzes The Formation Of Pppgpp Which I

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.6.5 [C]

Molecular weight: Translated: 38627; Mature: 38627

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWVTCDYSKKDVMRAGEQLISESVTDQELSTAMDVLSSWRAAHAYPMHALLIFLRTQSS
CCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
KIDANTIVVQRLKRTPSILDKLSRFPQMKLHRMQDISGCRAVVNNVNMVEKLSDSITNSR
CCCHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
TRHKLHKKDDYIQNPKLSGYRGIHLVYKYKGGKKAYSDYFVEIQLRSKIQHAWATSVEIV
HHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEEEHHHHHHHHHHHHHHHH
DIFTRQALKASHGSKEWLDFFMYASAEFAKLEKRPIGNHLDGIDTKLHLKKLADSLSVVN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLNAFAVSTQYVATKQDNRTDYFLLELTDTAQAIMVTQYTSADLDKATKAYLEKEKAAKN
HHHHHHEEHHEEEECCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCC
DSTYDVVLVAAGSMHALKAAYPNYFADSKAFLNYLAKVLS
CCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MKWVTCDYSKKDVMRAGEQLISESVTDQELSTAMDVLSSWRAAHAYPMHALLIFLRTQSS
CCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
KIDANTIVVQRLKRTPSILDKLSRFPQMKLHRMQDISGCRAVVNNVNMVEKLSDSITNSR
CCCHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
TRHKLHKKDDYIQNPKLSGYRGIHLVYKYKGGKKAYSDYFVEIQLRSKIQHAWATSVEIV
HHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEEEHHHHHHHHHHHHHHHH
DIFTRQALKASHGSKEWLDFFMYASAEFAKLEKRPIGNHLDGIDTKLHLKKLADSLSVVN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RLNAFAVSTQYVATKQDNRTDYFLLELTDTAQAIMVTQYTSADLDKATKAYLEKEKAAKN
HHHHHHEEHHEEEECCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCC
DSTYDVVLVAAGSMHALKAAYPNYFADSKAFLNYLAKVLS
CCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; GTP; ATP [C]

Specific reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate GTP + ATP = guanosine 3'-diphosphate 5'-triphosphate + AMP [C]

General reaction: Diphosphate transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA