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The map label for this gene is trpG [H]

Identifier: 39997477

GI number: 39997477

Start: 2610773

End: 2611345

Strand: Reverse

Name: trpG [H]

Synonym: GSU2382

Alternate gene names: 39997477

Gene position: 2611345-2610773 (Counterclockwise)

Preceding gene: 39997478

Following gene: 39997476

Centisome position: 68.46

GC content: 63.87

Gene sequence:

>573_bases
ATGCTCCTGATGATTGACAATTATGATTCCTTCACCTTCAATATCGTCCAGTATTTCGGCGAGCTGGGCGAGGATGTGCG
GGTCTTCCGCAACGACGGCATTACCCTGGATGAGATCGAGGCCCTGGCGCCCCGGCGCCTGGTCATCTCTCCCGGACCCT
GCTCGCCCGAGGAGGCGGGAATCTCCGTGGCCGCCATCCGGCATTTTGCCGGGAAGATTCCAATCCTCGGCGTCTGCCTT
GGCCACCAGTCCATCGGCGCGGCCTTCGGCGGCACGGTGGTCCGCAGCTCCACCCTCATGCACGGCAAGACATCGCCCAT
CCATCACAACGGCCAGGGGCTGTTCCGGGGGCTGCCCAACCCCTTCAACGCCACCCGCTACCACTCCCTGGTGGTGGAGC
GGGCCAGCCTTCCGGACTGCCTGGAGATCACCGCCTGGGTAGAGGAGGGGGAGATCATGGGGCTTGCCCACCGGGAGCTG
CCGGTCTGGGGGGTCCAGTTCCACCCCGAGTCGATCCTCACCGAGGGGGGGATGGATCTTCTGCGTAATTTCCTGGAGAT
AACACGGTCGTAG

Upstream 100 bases:

>100_bases
GTGGCCGACTCTGATCCGGCCTCCGAGTACCAGGAGACGGTCAACAAGGCCATGGCCGTGGTAAAGGCCATCGAGACCGC
GGAAAAGGGGTTGGACTGAC

Downstream 100 bases:

>100_bases
GGGCGAATCTTGTATTCGCCCGGAAACAGGGCGATCACAAGGATCGCCCCTACAGGTGAACCTGATGATCAAAAAAGCAA
TCGCCAAGGTGGTTGAGCGC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MLLMIDNYDSFTFNIVQYFGELGEDVRVFRNDGITLDEIEALAPRRLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQSIGAAFGGTVVRSSTLMHGKTSPIHHNGQGLFRGLPNPFNATRYHSLVVERASLPDCLEITAWVEEGEIMGLAHREL
PVWGVQFHPESILTEGGMDLLRNFLEITRS

Sequences:

>Translated_190_residues
MLLMIDNYDSFTFNIVQYFGELGEDVRVFRNDGITLDEIEALAPRRLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQSIGAAFGGTVVRSSTLMHGKTSPIHHNGQGLFRGLPNPFNATRYHSLVVERASLPDCLEITAWVEEGEIMGLAHREL
PVWGVQFHPESILTEGGMDLLRNFLEITRS
>Mature_190_residues
MLLMIDNYDSFTFNIVQYFGELGEDVRVFRNDGITLDEIEALAPRRLVISPGPCSPEEAGISVAAIRHFAGKIPILGVCL
GHQSIGAAFGGTVVRSSTLMHGKTSPIHHNGQGLFRGLPNPFNATRYHSLVVERASLPDCLEITAWVEEGEIMGLAHREL
PVWGVQFHPESILTEGGMDLLRNFLEITRS

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=144, Percent_Identity=36.1111111111111, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=65.945945945946, Blast_Score=266, Evalue=9e-73,
Organism=Escherichia coli, GI1787517, Length=187, Percent_Identity=43.3155080213904, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=27.3684210526316, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786215, Length=175, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=50.531914893617, Blast_Score=202, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=31.7535545023697, Blast_Score=92, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281365319, Length=141, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20865; Mature: 20865

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTFNIVQYFGELGEDVRVFRNDGITLDEIEALAPRRLVISPGPCSPEEAG
CEEEEECCCCHHHHHHHHHHHHCHHEEEHHCCCCCHHHHHHCCCCEEEECCCCCCHHHHC
ISVAAIRHFAGKIPILGVCLGHQSIGAAFGGTVVRSSTLMHGKTSPIHHNGQGLFRGLPN
CHHHHHHHHHCCCCEEEEEECCCHHHHHHCCHHHHCCEEECCCCCCCEECCCHHCCCCCC
PFNATRYHSLVVERASLPDCLEITAWVEEGEIMGLAHRELPVWGVQFHPESILTEGGMDL
CCCCHHHHHHHHHHCCCCCHHHHEEECCCCCEEEEECCCCCEEEEEECCHHHHHCCCHHH
LRNFLEITRS
HHHHHHHHCC
>Mature Secondary Structure
MLLMIDNYDSFTFNIVQYFGELGEDVRVFRNDGITLDEIEALAPRRLVISPGPCSPEEAG
CEEEEECCCCHHHHHHHHHHHHCHHEEEHHCCCCCHHHHHHCCCCEEEECCCCCCHHHHC
ISVAAIRHFAGKIPILGVCLGHQSIGAAFGGTVVRSSTLMHGKTSPIHHNGQGLFRGLPN
CHHHHHHHHHCCCCEEEEEECCCHHHHHHCCHHHHCCEEECCCCCCCEECCCHHCCCCCC
PFNATRYHSLVVERASLPDCLEITAWVEEGEIMGLAHRELPVWGVQFHPESILTEGGMDL
CCCCHHHHHHHHHHCCCCCHHHHEEECCCCCEEEEECCCCCEEEEEECCHHHHHCCCHHH
LRNFLEITRS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]