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The map label for this gene is trpD [H]

Identifier: 39997476

GI number: 39997476

Start: 2609656

End: 2610708

Strand: Reverse

Name: trpD [H]

Synonym: GSU2381

Alternate gene names: 39997476

Gene position: 2610708-2609656 (Counterclockwise)

Preceding gene: 39997477

Following gene: 39997475

Centisome position: 68.45

GC content: 67.43

Gene sequence:

>1053_bases
ATGATCAAAAAAGCAATCGCCAAGGTGGTTGAGCGCATCGACCTCACGGAAGCGGAAATGATCGAGGTGATGGACCAGAT
CATGTCCGGCGGGGCGACCCCGGCCCAGATCGCGGCCTTTATCACCGCCCTGCGGATGAAGGGTGAGACGGTGGAGGAGA
TCACCGGCGCGGCGCGGGTGATGCGGGACCGGGCAACCCCCATCCGGGTCGGCAAGGGAGTCCTCGATATCGACCGGGAC
GACATCAACATCGACCAGGAAACGATCCTGGACGTGGTGGGCACCGGCGGGGACGGCACCAACACCTTCAACATCTCCAC
CACCGTCTCCTTCGTGGTGGCGTCCTGCGGGGTCAAGGTGGCCAAACACGGCAACCGGGCCGTGTCGTCGGCCTGCGGCA
GCGCCGACGTGCTGGAATCCCTGGGCGTCAACCTGGACGTGACCCCGGAGACCGTGGAGCAGGCCATTGCGAAGATCGGC
ATCGGCTTCCTCTTCGCCCCGGCCCTGCACGGCGCCATGAAGCACGCCATCGGCCCCCGCAAGGAGATCGGCATCCGGAC
CATCTTCAATATCCTCGGCCCCCTCACCAACCCCGCCGGCGCCGACTGCCAGGTGCTGGGCGTCTACCGGGAGGAGCTGG
TGGAGCCCCTGGCCCGGGTCCTCCACAAGCTGGGCTGCCGCCGGGGCTTCGTGGTCCACGGCATGGACGGCATGGACGAG
ATCACCCTCACCCGCGAGACCCGCATCGCCGAGGTGACCCGGGACGGGGTGTCGGTGCGGACCATCACGCCGGAAGAATT
CGGGTTTGCCTCCTGCCCCGCCGGGGAGCTCCGCGGTGGCGACGCGGCCGGCAATGCCCGCATCGTCCGCGGCATCCTTG
AAGGGGCAACCGGGCCGCGCCGCGACGTGGTACTCCTGAATGCCGCTTTCGGCCTGGTGGCCGCCGGCAAGGCCGTTGAC
CCGGCTGAAGGGGTTCGCATCGCCGCCGAGGCCATCGATTCGGGCCGTGCCCTGGCAAAGCTGGAAGAACTCATCACCCT
GACCAACGAGTAA

Upstream 100 bases:

>100_bases
CTTCTGCGTAATTTCCTGGAGATAACACGGTCGTAGGGGCGAATCTTGTATTCGCCCGGAAACAGGGCGATCACAAGGAT
CGCCCCTACAGGTGAACCTG

Downstream 100 bases:

>100_bases
ACCCATGACCGATACCCCCGATATCCTGAAGAAGATCGTCGAGCACAAGCGGGGCGAAGTGGCTGCGGCCCGGTCCGCTG
CCCCCCTTGCCGAGGTGAAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGGATPAQIAAFITALRMKGETVEEITGAARVMRDRATPIRVGKGVLDIDRD
DINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKVAKHGNRAVSSACGSADVLESLGVNLDVTPETVEQAIAKIG
IGFLFAPALHGAMKHAIGPRKEIGIRTIFNILGPLTNPAGADCQVLGVYREELVEPLARVLHKLGCRRGFVVHGMDGMDE
ITLTRETRIAEVTRDGVSVRTITPEEFGFASCPAGELRGGDAAGNARIVRGILEGATGPRRDVVLLNAAFGLVAAGKAVD
PAEGVRIAAEAIDSGRALAKLEELITLTNE

Sequences:

>Translated_350_residues
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGGATPAQIAAFITALRMKGETVEEITGAARVMRDRATPIRVGKGVLDIDRD
DINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKVAKHGNRAVSSACGSADVLESLGVNLDVTPETVEQAIAKIG
IGFLFAPALHGAMKHAIGPRKEIGIRTIFNILGPLTNPAGADCQVLGVYREELVEPLARVLHKLGCRRGFVVHGMDGMDE
ITLTRETRIAEVTRDGVSVRTITPEEFGFASCPAGELRGGDAAGNARIVRGILEGATGPRRDVVLLNAAFGLVAAGKAVD
PAEGVRIAAEAIDSGRALAKLEELITLTNE
>Mature_350_residues
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGGATPAQIAAFITALRMKGETVEEITGAARVMRDRATPIRVGKGVLDIDRD
DINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKVAKHGNRAVSSACGSADVLESLGVNLDVTPETVEQAIAKIG
IGFLFAPALHGAMKHAIGPRKEIGIRTIFNILGPLTNPAGADCQVLGVYREELVEPLARVLHKLGCRRGFVVHGMDGMDE
ITLTRETRIAEVTRDGVSVRTITPEEFGFASCPAGELRGGDAAGNARIVRGILEGATGPRRDVVLLNAAFGLVAAGKAVD
PAEGVRIAAEAIDSGRALAKLEELITLTNE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=294, Percent_Identity=38.4353741496599, Blast_Score=202, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=329, Percent_Identity=31.9148936170213, Blast_Score=143, Evalue=4e-35,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36816; Mature: 36816

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGGATPAQIAAFITALRMKGETVEEITGAARV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
MRDRATPIRVGKGVLDIDRDDINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKV
HHHCCCCEECCCCEEECCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCHHH
AKHGNRAVSSACGSADVLESLGVNLDVTPETVEQAIAKIGIGFLFAPALHGAMKHAIGPR
HHCCCHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KEIGIRTIFNILGPLTNPAGADCQVLGVYREELVEPLARVLHKLGCRRGFVVHGMDGMDE
HHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCC
ITLTRETRIAEVTRDGVSVRTITPEEFGFASCPAGELRGGDAAGNARIVRGILEGATGPR
EEEEHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
RDVVLLNAAFGLVAAGKAVDPAEGVRIAAEAIDSGRALAKLEELITLTNE
CCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKKAIAKVVERIDLTEAEMIEVMDQIMSGGATPAQIAAFITALRMKGETVEEITGAARV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
MRDRATPIRVGKGVLDIDRDDINIDQETILDVVGTGGDGTNTFNISTTVSFVVASCGVKV
HHHCCCCEECCCCEEECCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCHHH
AKHGNRAVSSACGSADVLESLGVNLDVTPETVEQAIAKIGIGFLFAPALHGAMKHAIGPR
HHCCCHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KEIGIRTIFNILGPLTNPAGADCQVLGVYREELVEPLARVLHKLGCRRGFVVHGMDGMDE
HHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCC
ITLTRETRIAEVTRDGVSVRTITPEEFGFASCPAGELRGGDAAGNARIVRGILEGATGPR
EEEEHHHHHHHHHHCCCEEEEECHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
RDVVLLNAAFGLVAAGKAVDPAEGVRIAAEAIDSGRALAKLEELITLTNE
CCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA