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The map label for this gene is celB [H]

Identifier: 39997111

GI number: 39997111

Start: 2205968

End: 2207386

Strand: Reverse

Name: celB [H]

Synonym: GSU2013

Alternate gene names: 39997111

Gene position: 2207386-2205968 (Counterclockwise)

Preceding gene: 39997114

Following gene: 39997110

Centisome position: 57.87

GC content: 59.62

Gene sequence:

>1419_bases
ATGCATCGCATTACCTTCGGCACTTCCGGTTGGCGTGGCATTCTCTGCGAAGATTTCACCTTCGAGAACGTAAAGGTGGT
GAGTCAGGCCATTGCCGACCATGTGAAAGCAATAGGCGAACAGGACAAGGGGATCATCGTCGCCTATGACACCCGATTCA
TGGGAGAGCGTTTCGCCAAGGAAACGGTCCGCGTGCTGGCCGGTGCCGGCGTCAAGGCCTATTTCTGCCGGCGCGACACG
CCTACCCCGGTAATTTCCTTCGAGATTCTGCGCCGCGGTACTGCTGGAGCAGTCAACTTTACCGCAAGCCATAACCCGCC
CGAATACAACGGCATCAAGTTTTCTCCGTCTTGGGGCGGACCGGCGCTGCCCGAGACGACCGGCGACATTGAGCGCCGGG
CCAACGAAATGATGGGCGAGGTCTGCTACCGGGAGATGGCCCTTGACGAGGCGGTGAAGGCGGGGCTGCTGGAAGAGATC
GACCCCCGGGAGGAGTACCTGAAGGCCCTGGAGTCAAAGGTCGACTTCGACGCCATCGGTCGTGTCGGTTCCGTTGCCGT
GAACGCTCTCTACGGGACCGGCCGGGGGTATCTGGAAGAGCCCCTCATAACTCGGGGACTGGACGTGAAGGCGATCAACA
TGCATCGCGATCCCTACTTCGGAGGTTTTCCGCCCGAACCGTCCGAGAAGTACATCCAGGATTTCATCCGGCTCGTGAAA
GATGACCCGGCCATAAGGCTGGGGATCGCCACCGACGGCGACGCCGACCGCTTCGGTATTGTGGACGGCGACGGTACCTT
CATTGAGCCGAATTACATCATTGCTCTGCTGTTCGACTATTTGGTCCGGGTCAGGAAAATGACCGGCGCGGTGGCCCGCA
GCGTGGCAACGTCCCACCTTGTGGATGCGGTGGCTAAGAAGCACGGCATCGAAGTTATCGAGACGCCGGTGGGCTTCAAG
TATATCGGCGAACTGATCAGCCAGGACCGGATCATTATCGGCGGAGAGGAGAGCGCCGGCCTTTCCATTAAGGGACACGT
GCCTGAGAAGGATGGTATTCTCGCCTGTTTCCTGGTTGCCGAAATGGTTGCCAGGGAAGGGCTGTCCGTGAAGGCTCTGC
TGGCAAGGCTCTATGAGGAGGTCGGCACCTTTGTGACAAAACGGGAGAACATTACCCTTTCTCCCGCCGTGGAAGAGGGC
TACGCCGAAAAGCAGCGCCAGGCGCCCGATTCCTTTGCCGGCCTGAAGGTGACGCAAAAGGTTACCGTGGACGGCAGCAA
GTTCATCCTTGAGGACGACAGTTGGCTGCTGTTCCGCAAATCAGGGACCGAGCCGGTGGTTCGCCTGTACGCCGAGGCGT
CCAGCGAGGAGAAGCTCGCGGCGGTCATGGCTGCCGGGAAACAGTTCATCCTCGGCTAA

Upstream 100 bases:

>100_bases
GCAGGGTTGACTCCCCACGGGGTATGTATTACCCTTTGGTGGCCGGTTAATCACGGTCTCCACGGCTCGGTGGCGGCCAT
GCTCCCAGGGGAGGGACTTC

Downstream 100 bases:

>100_bases
TCAGCAGACGAACAGACAGACGGACGGTGCAACGGCGCCCATCCGCCCAAGGCGGCGGGGCGCCTTTTTCTTTGCCGGGT
GAAAACGGAGTATTGAATAC

Product: phosphoglucomutase/phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MHRITFGTSGWRGILCEDFTFENVKVVSQAIADHVKAIGEQDKGIIVAYDTRFMGERFAKETVRVLAGAGVKAYFCRRDT
PTPVISFEILRRGTAGAVNFTASHNPPEYNGIKFSPSWGGPALPETTGDIERRANEMMGEVCYREMALDEAVKAGLLEEI
DPREEYLKALESKVDFDAIGRVGSVAVNALYGTGRGYLEEPLITRGLDVKAINMHRDPYFGGFPPEPSEKYIQDFIRLVK
DDPAIRLGIATDGDADRFGIVDGDGTFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHLVDAVAKKHGIEVIETPVGFK
YIGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVAEMVAREGLSVKALLARLYEEVGTFVTKRENITLSPAVEEG
YAEKQRQAPDSFAGLKVTQKVTVDGSKFILEDDSWLLFRKSGTEPVVRLYAEASSEEKLAAVMAAGKQFILG

Sequences:

>Translated_472_residues
MHRITFGTSGWRGILCEDFTFENVKVVSQAIADHVKAIGEQDKGIIVAYDTRFMGERFAKETVRVLAGAGVKAYFCRRDT
PTPVISFEILRRGTAGAVNFTASHNPPEYNGIKFSPSWGGPALPETTGDIERRANEMMGEVCYREMALDEAVKAGLLEEI
DPREEYLKALESKVDFDAIGRVGSVAVNALYGTGRGYLEEPLITRGLDVKAINMHRDPYFGGFPPEPSEKYIQDFIRLVK
DDPAIRLGIATDGDADRFGIVDGDGTFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHLVDAVAKKHGIEVIETPVGFK
YIGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVAEMVAREGLSVKALLARLYEEVGTFVTKRENITLSPAVEEG
YAEKQRQAPDSFAGLKVTQKVTVDGSKFILEDDSWLLFRKSGTEPVVRLYAEASSEEKLAAVMAAGKQFILG
>Mature_472_residues
MHRITFGTSGWRGILCEDFTFENVKVVSQAIADHVKAIGEQDKGIIVAYDTRFMGERFAKETVRVLAGAGVKAYFCRRDT
PTPVISFEILRRGTAGAVNFTASHNPPEYNGIKFSPSWGGPALPETTGDIERRANEMMGEVCYREMALDEAVKAGLLEEI
DPREEYLKALESKVDFDAIGRVGSVAVNALYGTGRGYLEEPLITRGLDVKAINMHRDPYFGGFPPEPSEKYIQDFIRLVK
DDPAIRLGIATDGDADRFGIVDGDGTFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHLVDAVAKKHGIEVIETPVGFK
YIGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVAEMVAREGLSVKALLARLYEEVGTFVTKRENITLSPAVEEG
YAEKQRQAPDSFAGLKVTQKVTVDGSKFILEDDSWLLFRKSGTEPVVRLYAEASSEEKLAAVMAAGKQFILG

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=501, Percent_Identity=27.7445109780439, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI290463102, Length=527, Percent_Identity=27.3244781783681, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI133922562, Length=489, Percent_Identity=26.3803680981595, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI290463104, Length=342, Percent_Identity=27.7777777777778, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786904, Length=488, Percent_Identity=29.0983606557377, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788361, Length=467, Percent_Identity=26.338329764454, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789566, Length=466, Percent_Identity=25.5364806866953, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17535441, Length=514, Percent_Identity=29.7665369649805, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71993870, Length=511, Percent_Identity=23.8747553816047, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323752, Length=478, Percent_Identity=25.7322175732218, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6322722, Length=429, Percent_Identity=27.2727272727273, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17864244, Length=527, Percent_Identity=28.6527514231499, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI20129809, Length=529, Percent_Identity=24.952741020794, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24651977, Length=452, Percent_Identity=25.6637168141593, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 51759; Mature: 51759

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRITFGTSGWRGILCEDFTFENVKVVSQAIADHVKAIGEQDKGIIVAYDTRFMGERFAK
CCEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHH
ETVRVLAGAGVKAYFCRRDTPTPVISFEILRRGTAGAVNFTASHNPPEYNGIKFSPSWGG
HHHHHHHCCCCEEEEECCCCCCCEEEHHHHHCCCCCEEEEECCCCCCCCCCEEECCCCCC
PALPETTGDIERRANEMMGEVCYREMALDEAVKAGLLEEIDPREEYLKALESKVDFDAIG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHC
RVGSVAVNALYGTGRGYLEEPLITRGLDVKAINMHRDPYFGGFPPEPSEKYIQDFIRLVK
CHHHHHHHHEECCCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHC
DDPAIRLGIATDGDADRFGIVDGDGTFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHL
CCCCEEEEEECCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAVAKKHGIEVIETPVGFKYIGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVA
HHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHH
EMVAREGLSVKALLARLYEEVGTFVTKRENITLSPAVEEGYAEKQRQAPDSFAGLKVTQK
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCCCCCCEEEEE
VTVDGSKFILEDDSWLLFRKSGTEPVVRLYAEASSEEKLAAVMAAGKQFILG
EEECCCEEEEECCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MHRITFGTSGWRGILCEDFTFENVKVVSQAIADHVKAIGEQDKGIIVAYDTRFMGERFAK
CCEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHH
ETVRVLAGAGVKAYFCRRDTPTPVISFEILRRGTAGAVNFTASHNPPEYNGIKFSPSWGG
HHHHHHHCCCCEEEEECCCCCCCEEEHHHHHCCCCCEEEEECCCCCCCCCCEEECCCCCC
PALPETTGDIERRANEMMGEVCYREMALDEAVKAGLLEEIDPREEYLKALESKVDFDAIG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHC
RVGSVAVNALYGTGRGYLEEPLITRGLDVKAINMHRDPYFGGFPPEPSEKYIQDFIRLVK
CHHHHHHHHEECCCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHC
DDPAIRLGIATDGDADRFGIVDGDGTFIEPNYIIALLFDYLVRVRKMTGAVARSVATSHL
CCCCEEEEEECCCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAVAKKHGIEVIETPVGFKYIGELISQDRIIIGGEESAGLSIKGHVPEKDGILACFLVA
HHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHH
EMVAREGLSVKALLARLYEEVGTFVTKRENITLSPAVEEGYAEKQRQAPDSFAGLKVTQK
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCCCCCCEEEEE
VTVDGSKFILEDDSWLLFRKSGTEPVVRLYAEASSEEKLAAVMAAGKQFILG
EEECCCEEEEECCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]