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The map label for this gene is nifU [H]

Identifier: 39997110

GI number: 39997110

Start: 2204955

End: 2205812

Strand: Reverse

Name: nifU [H]

Synonym: GSU2012

Alternate gene names: 39997110

Gene position: 2205812-2204955 (Counterclockwise)

Preceding gene: 39997111

Following gene: 39997109

Centisome position: 57.83

GC content: 57.69

Gene sequence:

>858_bases
ATGTGGGATTACACTGAGAAGGTTCGGGAGCACTTCCTGAATCCCAGAAACGTTGGAGAGATACCCGATGCGGATGCGGT
GGGCGAGGTGGGAAGCCTTGCCTGTGGCGATGCGCTCAAGCTCTATATCAAACTTGACGAGGCCAAGGAGAAGATCGTCG
ATGCCAAATTCCAGACCTTCGGTTGCGCCAGCGCCATTGCATCGTCGTCGGCCCTGACCGAGATCATAAAAGGAAAGACC
CTCGACGAGGCCCTGGCAACCACCAATCAGGAGATCGCCGAGTTTCTGGGAGGGCTTCCCGAGGAGAAGATGCACTGTTC
GGTCATGGGGCAAGAGGCCCTCGAGGTGGCAATTGCCAAGTTCCGCGGCGGTCCGGTTCCGACTCACCATGACCACGGTC
ACGAGGAGGCCGAGGGTGAGATTGTCTGCAAGTGCTTCGGTCTGACCGATGTCTTCCTGCGCAAGGTGATCGAGACGAAC
AAGCTGACCACTGCCGAGCAGGTGACCCATTTCACCAAGGCCGGCGGAGCATGCGGCGGATGTATCCCTAAAATCAAGGA
GATCATCAATGAGGTTCTGGGCGCCAAACCAGCGGAAGAACACAAGCGGCCCGAGAAGCTGACCAACCTTCGCAAGATGC
AGCTTATCCAGGAGACCCTGGAGAAGGAGATTCGCCCTCAGCTCTGGGCCGATGGCGGAGATCTTGAGTTGATAGATATT
AGCGGCAGCGAAGTGCAGATTGCATTCCGCAAAGCGTGTGCCGGGTGCGCCGCTTCGGGCAATACCGCCAAGTTCGTCGA
GATGAAGCTGCGCGAGCTTGTGGCCGAGGATATCACTGTCACGGAGGTGGAGGGATGA

Upstream 100 bases:

>100_bases
CGGGGCGCCTTTTTCTTTGCCGGGTGAAAACGGAGTATTGAATACCTGACAATTTTGCTATAGTATTATGAAGCGATGAC
TACAATCCGAGGAGGAATCC

Downstream 100 bases:

>100_bases
AGGAGATCTACCTGGACAACAACGCCACCACCAAGGTGGACGAGGCTGTTTTCGAGGAGATGCGTCCCTATTTCTGTGAC
CTCTACGGCAACCCCAGCTC

Product: NifU family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MWDYTEKVREHFLNPRNVGEIPDADAVGEVGSLACGDALKLYIKLDEAKEKIVDAKFQTFGCASAIASSSALTEIIKGKT
LDEALATTNQEIAEFLGGLPEEKMHCSVMGQEALEVAIAKFRGGPVPTHHDHGHEEAEGEIVCKCFGLTDVFLRKVIETN
KLTTAEQVTHFTKAGGACGGCIPKIKEIINEVLGAKPAEEHKRPEKLTNLRKMQLIQETLEKEIRPQLWADGGDLELIDI
SGSEVQIAFRKACAGCAASGNTAKFVEMKLRELVAEDITVTEVEG

Sequences:

>Translated_285_residues
MWDYTEKVREHFLNPRNVGEIPDADAVGEVGSLACGDALKLYIKLDEAKEKIVDAKFQTFGCASAIASSSALTEIIKGKT
LDEALATTNQEIAEFLGGLPEEKMHCSVMGQEALEVAIAKFRGGPVPTHHDHGHEEAEGEIVCKCFGLTDVFLRKVIETN
KLTTAEQVTHFTKAGGACGGCIPKIKEIINEVLGAKPAEEHKRPEKLTNLRKMQLIQETLEKEIRPQLWADGGDLELIDI
SGSEVQIAFRKACAGCAASGNTAKFVEMKLRELVAEDITVTEVEG
>Mature_285_residues
MWDYTEKVREHFLNPRNVGEIPDADAVGEVGSLACGDALKLYIKLDEAKEKIVDAKFQTFGCASAIASSSALTEIIKGKT
LDEALATTNQEIAEFLGGLPEEKMHCSVMGQEALEVAIAKFRGGPVPTHHDHGHEEAEGEIVCKCFGLTDVFLRKVIETN
KLTTAEQVTHFTKAGGACGGCIPKIKEIINEVLGAKPAEEHKRPEKLTNLRKMQLIQETLEKEIRPQLWADGGDLELIDI
SGSEVQIAFRKACAGCAASGNTAKFVEMKLRELVAEDITVTEVEG

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=122, Percent_Identity=50.8196721311475, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI24307953, Length=123, Percent_Identity=49.5934959349593, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI1788878, Length=123, Percent_Identity=51.219512195122, Blast_Score=117, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17543474, Length=122, Percent_Identity=50, Blast_Score=113, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6325122, Length=124, Percent_Identity=45.9677419354839, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324800, Length=128, Percent_Identity=44.53125, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355597, Length=122, Percent_Identity=52.4590163934426, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR016217
- InterPro:   IPR010238
- InterPro:   IPR001075
- InterPro:   IPR002871
- ProDom:   PD002830 [H]

Pfam domain/function: PF04324 Fer2_BFD; PF01106 NifU; PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 30991; Mature: 30991

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDYTEKVREHFLNPRNVGEIPDADAVGEVGSLACGDALKLYIKLDEAKEKIVDAKFQTF
CCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCHHHCCCEEEEEEEHHHHHHHHHHHHHHH
GCASAIASSSALTEIIKGKTLDEALATTNQEIAEFLGGLPEEKMHCSVMGQEALEVAIAK
HHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FRGGPVPTHHDHGHEEAEGEIVCKCFGLTDVFLRKVIETNKLTTAEQVTHFTKAGGACGG
HCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
CIPKIKEIINEVLGAKPAEEHKRPEKLTNLRKMQLIQETLEKEIRPQLWADGGDLELIDI
HHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCEEEEEC
SGSEVQIAFRKACAGCAASGNTAKFVEMKLRELVAEDITVTEVEG
CCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MWDYTEKVREHFLNPRNVGEIPDADAVGEVGSLACGDALKLYIKLDEAKEKIVDAKFQTF
CCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCHHHCCCEEEEEEEHHHHHHHHHHHHHHH
GCASAIASSSALTEIIKGKTLDEALATTNQEIAEFLGGLPEEKMHCSVMGQEALEVAIAK
HHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FRGGPVPTHHDHGHEEAEGEIVCKCFGLTDVFLRKVIETNKLTTAEQVTHFTKAGGACGG
HCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
CIPKIKEIINEVLGAKPAEEHKRPEKLTNLRKMQLIQETLEKEIRPQLWADGGDLELIDI
HHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCEEEEEC
SGSEVQIAFRKACAGCAASGNTAKFVEMKLRELVAEDITVTEVEG
CCCEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496536 [H]