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The map label for this gene is coaX

Identifier: 39997032

GI number: 39997032

Start: 2115919

End: 2116686

Strand: Reverse

Name: coaX

Synonym: GSU1934

Alternate gene names: 39997032

Gene position: 2116686-2115919 (Counterclockwise)

Preceding gene: 39997033

Following gene: 39997031

Centisome position: 55.5

GC content: 59.77

Gene sequence:

>768_bases
GTGCTTCTTGTTATAGACGTGGGTAATACCAATATCGTGCTCGGGATTTACGATGGCGAGCGCCTGGTGAGGGATTGGCG
GGTCTCCACGGACAAGGCCCGTACTACCGACGAGTACGGTATTCTCATAAATGAGTTGTTCCGCTTGGCGGGCCTTGGGC
TCGATCAGATCCGCGCGGTGATCATCTCCTCGGTGGTGCCGCCCCTCACCGGCGTGCTGGAGCGTCTTTCCCTGGGGTAT
TTCGGGATGCGTCCCCTGGTGGTGGGACCGGGCATCAAGACAGGCATGCCAATCCAGTACGACAACCCCCGGGAGGTGGG
GGCCGACCGGATCGTGAACGCGGTGGCGGGGTACGAGAAGTACCGCACCTCTCTCATTATCGTCGATTTCGGCACCGCTA
CCACGTTCGACTACGTGAACCGCAAGGGAGAGTACTGCGGAGGGGCCATCGCGCCGGGACTCGTCATTTCCACCGAGGCC
CTGTTCCAGCGGGCCAGCAAGCTGCCCAGGGTTGATATCATACGTCCGTCCGCGATCATTGCCAGGAACACGGTCAATTC
GATGCAGGCGGGAATTTACTATGGTTACGTGGGGCTCGTAGACGAGATCGTCACCCGGATGAAGGCCGAGAGCAAGGATG
CGCCCCGGGTTATCGCTACCGGAGGGTTGGCGTCCCTCATAGCGCCGGAGTCCAAGACCATCGAAGCCGTCGAGGAATAT
CTGACACTGGAGGGATTGCGCATACTGTACGAACGAAACAGGGAGTGA

Upstream 100 bases:

>100_bases
CTCTGGAGCGGGTTCTGGCAGGTGACGTTTCGCTCGAAGGTTGAGGGGACGGCGGTAACGCGCCGTATTCCCGGGGGACG
TCTCACCGTGTGGAGGAAGT

Downstream 100 bases:

>100_bases
GACAGCGGATAATTGCAGCGGATGTGAAGTGCCCACTGTGGGAATCACGGGTCGACGCCGACCTCTACCTTACACGTCAC
GGGAGGATGTATGGGCAAGT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLLVIDVGNTNIVLGIYDGERLVRDWRVSTDKARTTDEYGILINELFRLAGLGLDQIRAVIISSVVPPLTGVLERLSLGY
FGMRPLVVGPGIKTGMPIQYDNPREVGADRIVNAVAGYEKYRTSLIIVDFGTATTFDYVNRKGEYCGGAIAPGLVISTEA
LFQRASKLPRVDIIRPSAIIARNTVNSMQAGIYYGYVGLVDEIVTRMKAESKDAPRVIATGGLASLIAPESKTIEAVEEY
LTLEGLRILYERNRE

Sequences:

>Translated_255_residues
MLLVIDVGNTNIVLGIYDGERLVRDWRVSTDKARTTDEYGILINELFRLAGLGLDQIRAVIISSVVPPLTGVLERLSLGY
FGMRPLVVGPGIKTGMPIQYDNPREVGADRIVNAVAGYEKYRTSLIIVDFGTATTFDYVNRKGEYCGGAIAPGLVISTEA
LFQRASKLPRVDIIRPSAIIARNTVNSMQAGIYYGYVGLVDEIVTRMKAESKDAPRVIATGGLASLIAPESKTIEAVEEY
LTLEGLRILYERNRE
>Mature_255_residues
MLLVIDVGNTNIVLGIYDGERLVRDWRVSTDKARTTDEYGILINELFRLAGLGLDQIRAVIISSVVPPLTGVLERLSLGY
FGMRPLVVGPGIKTGMPIQYDNPREVGADRIVNAVAGYEKYRTSLIIVDFGTATTFDYVNRKGEYCGGAIAPGLVISTEA
LFQRASKLPRVDIIRPSAIIARNTVNSMQAGIYYGYVGLVDEIVTRMKAESKDAPRVIATGGLASLIAPESKTIEAVEEY
LTLEGLRILYERNRE

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_GEOSL (Q74BU2)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952983.1
- ProteinModelPortal:   Q74BU2
- SMR:   Q74BU2
- GeneID:   2685422
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1934
- NMPDR:   fig|243231.1.peg.1921
- TIGR:   GSU1934
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13321
- BioCyc:   GSUL243231:GSU_1934-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27973; Mature: 27973

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVIDVGNTNIVLGIYDGERLVRDWRVSTDKARTTDEYGILINELFRLAGLGLDQIRAV
CEEEEEECCCEEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
IISSVVPPLTGVLERLSLGYFGMRPLVVGPGIKTGMPIQYDNPREVGADRIVNAVAGYEK
HHHHHCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTSLIIVDFGTATTFDYVNRKGEYCGGAIAPGLVISTEALFQRASKLPRVDIIRPSAII
HCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEECCCHHH
ARNTVNSMQAGIYYGYVGLVDEIVTRMKAESKDAPRVIATGGLASLIAPESKTIEAVEEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCHHHHHHHHH
LTLEGLRILYERNRE
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLVIDVGNTNIVLGIYDGERLVRDWRVSTDKARTTDEYGILINELFRLAGLGLDQIRAV
CEEEEEECCCEEEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
IISSVVPPLTGVLERLSLGYFGMRPLVVGPGIKTGMPIQYDNPREVGADRIVNAVAGYEK
HHHHHCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTSLIIVDFGTATTFDYVNRKGEYCGGAIAPGLVISTEALFQRASKLPRVDIIRPSAII
HCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCEEEECCCHHH
ARNTVNSMQAGIYYGYVGLVDEIVTRMKAESKDAPRVIATGGLASLIAPESKTIEAVEEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCHHHHHHHHH
LTLEGLRILYERNRE
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA