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The map label for this gene is fusA-1 [H]

Identifier: 39997031

GI number: 39997031

Start: 2113735

End: 2115828

Strand: Reverse

Name: fusA-1 [H]

Synonym: GSU1933

Alternate gene names: 39997031

Gene position: 2115828-2113735 (Counterclockwise)

Preceding gene: 39997032

Following gene: 39997030

Centisome position: 55.47

GC content: 58.98

Gene sequence:

>2094_bases
ATGGGCAAGTATGATACCGCGAAGCTGAGAAACCTTGGAATTGTGGCCCACGGGGGCGCCGGCAAGACCTCGCTCACCGA
GGCCATCCTGTACACGGCCGGGATGATCGACCGCCTCGGCCGGGTGGACGACGGCACCTCCACCATGGATTTCGAGCCCG
AGGAGATCAAGCGCAAGATCACGATTTCGTCCTCCCTGGATCACTGCGAGTGGAACGGTCATTCACTCCATATTGTCGAT
ACCCCTGGCTACGGCAACTTCATCGCCGATACCCGGGCCTGCATGCGTGCTCTTGGCGGCTGCGTTGTCATTCTTTCTGC
CATCTCGGGGGTCAAGGTGCAGACCGAGGAGGTCTGGGAGTGGGCCAACGAGTTCGAGTTGCCGCGCATCGCCTTCGTGA
ACAAGATGGACCGGGAATATGCCAATTTCCTGCGGGCCATCGACGATATGGAGAAATCACTCAAGGCTCGTGGGGTTGCC
GTCCAGATGCCGCTTGGCGCGGCTGAGACCTTCGAGGGGGTCATCGACCTGATCACGATGAAAGCGTACCGTTACGCCAA
AGACACCTCCGGCACCTTCAAGGAAGAAGAAATTCCCGCCGAGTATCGTGACGAGGCCCAGCGGCTCCGCGAGCATCTGG
TTGAAACCGTGGCCGAGGCTTATGACGGCCTCACCGAGAAGTACCTGGAAACGGGTGAGCTGACCGAGGAGGAGATCCTG
GACGGCCTGCGGGTGGGAACCCTGCGTTACACCTTCACACCGGTCTTCTGCGGTTCGGCCACCATGAACATCGGCGTGCG
TCATCTGCTGGATTATATCTGCGCCTGCCTGCCGTCACCCCAGGATCGGGGAGCCGTTGCCGGTGCCAACCCCAAGAACG
GCGAACCGATCGAGCGGCGCCCGGAGGAGAGTGAGCCCTTCTCTGCCCTGGTCTTCAAGACCACCTCTGATCCCTACACC
GGCAAGATATCCATCTTCCGGGTCTATTCCGGCGTCCTCAATTCCGACTCCACCATCTACAATCCGGTCCGTGAATGCGA
GGAGCGGATCGGCCAGATCTATGAACTGGAGGGCAAAAAGCAGAAGCCGATCAAGCAGGCCGTTGCCGGCGACATCGTTG
CGGTTGCCAAGCTCAAGGAAACCCTCACGGGCGACACCCTCTGCGACAAGGATCACCCCATCATCTACGAACCGGCGAAA
CCGCTCCAGCCGGTGATTTCCTACGCGGTCCAGCCCAAGACCAAGAATGACGAGGACAAGATCCACGGTGCACTCCAGAG
GCTCATGGAAGAGGATCAGACCATTCAGGTCCGCCGCGACGAGAAGACCCGGGAACTGATTCTTTCAGGCATGGGTCAAG
TTCACCTGGAAGTGACCATCGAGAAGCTCAAGCGGAAGTTCAACGTAGACGTGGAAATGAAGACGCAGAAAGTTCCCTAC
CTTGAAACCTTCAAAGCCCAGGTCAAGGCCCAAGGCAAGTACAAGAAGCAATCCGGCGGACGGGGCCAGTACGGCGACTG
CTGGGTTGAATTCTCGCCGCTCGGCCGGGGAGATGGGTTCCAGTTCGAGGATAAGATCGTGGGTGGTGTTATACCCCGAC
AGTATATTCCTGCCGTGGAAAAAGGGATCTTCGAGGCATCCCAGGACGGCTTCCTTGCCGGCTACCCCCTGGTGGACTTC
AAGGCGGCGGTCTATGACGGCTCTTTCCACACGGTTGATTCGTCGGAGATGGCGTTCAAGGTGGCCGGCTCCCTCGCGTT
CAAAAAGGCCATGGAGACGGCCAAGGTGGTGCTGCTGGAGCCGATGATGAACATGAAGGTCACCGTGCCCGAAGAGACCA
TGGGCGACGTCATCGGTGACCTGAACTCCCGTCGGGGTAAGGTGGTGGGGGTTGAGCCCAAGGCCAATTCCCAGATCATC
CGTGCCGTGGTCCCCATGTCCGAGGTGCTGGCCTATGCCAACGACCTCAAGTCCATGACGAGCGACCGAGGGCTTTTCAC
CATGGAATTCTCCCACTACGAGGAAGTCCCGACGCATCTGGCGCAGAAAGTCGTTGCCGAGTCCCAGAAGGCGGAAGGCA
AGAATAATCATTAA

Upstream 100 bases:

>100_bases
CAGGGAGTGAGACAGCGGATAATTGCAGCGGATGTGAAGTGCCCACTGTGGGAATCACGGGTCGACGCCGACCTCTACCT
TACACGTCACGGGAGGATGT

Downstream 100 bases:

>100_bases
GCTGCAGCGGGTCACAGGCGGCGGACGCACCGACAGACGGCGCTCCGCGCCCTGCGCACGGCAGCGGTTTTCGGAGGAGG
TAACGAGCGTTATGAACATC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MGKYDTAKLRNLGIVAHGGAGKTSLTEAILYTAGMIDRLGRVDDGTSTMDFEPEEIKRKITISSSLDHCEWNGHSLHIVD
TPGYGNFIADTRACMRALGGCVVILSAISGVKVQTEEVWEWANEFELPRIAFVNKMDREYANFLRAIDDMEKSLKARGVA
VQMPLGAAETFEGVIDLITMKAYRYAKDTSGTFKEEEIPAEYRDEAQRLREHLVETVAEAYDGLTEKYLETGELTEEEIL
DGLRVGTLRYTFTPVFCGSATMNIGVRHLLDYICACLPSPQDRGAVAGANPKNGEPIERRPEESEPFSALVFKTTSDPYT
GKISIFRVYSGVLNSDSTIYNPVRECEERIGQIYELEGKKQKPIKQAVAGDIVAVAKLKETLTGDTLCDKDHPIIYEPAK
PLQPVISYAVQPKTKNDEDKIHGALQRLMEEDQTIQVRRDEKTRELILSGMGQVHLEVTIEKLKRKFNVDVEMKTQKVPY
LETFKAQVKAQGKYKKQSGGRGQYGDCWVEFSPLGRGDGFQFEDKIVGGVIPRQYIPAVEKGIFEASQDGFLAGYPLVDF
KAAVYDGSFHTVDSSEMAFKVAGSLAFKKAMETAKVVLLEPMMNMKVTVPEETMGDVIGDLNSRRGKVVGVEPKANSQII
RAVVPMSEVLAYANDLKSMTSDRGLFTMEFSHYEEVPTHLAQKVVAESQKAEGKNNH

Sequences:

>Translated_697_residues
MGKYDTAKLRNLGIVAHGGAGKTSLTEAILYTAGMIDRLGRVDDGTSTMDFEPEEIKRKITISSSLDHCEWNGHSLHIVD
TPGYGNFIADTRACMRALGGCVVILSAISGVKVQTEEVWEWANEFELPRIAFVNKMDREYANFLRAIDDMEKSLKARGVA
VQMPLGAAETFEGVIDLITMKAYRYAKDTSGTFKEEEIPAEYRDEAQRLREHLVETVAEAYDGLTEKYLETGELTEEEIL
DGLRVGTLRYTFTPVFCGSATMNIGVRHLLDYICACLPSPQDRGAVAGANPKNGEPIERRPEESEPFSALVFKTTSDPYT
GKISIFRVYSGVLNSDSTIYNPVRECEERIGQIYELEGKKQKPIKQAVAGDIVAVAKLKETLTGDTLCDKDHPIIYEPAK
PLQPVISYAVQPKTKNDEDKIHGALQRLMEEDQTIQVRRDEKTRELILSGMGQVHLEVTIEKLKRKFNVDVEMKTQKVPY
LETFKAQVKAQGKYKKQSGGRGQYGDCWVEFSPLGRGDGFQFEDKIVGGVIPRQYIPAVEKGIFEASQDGFLAGYPLVDF
KAAVYDGSFHTVDSSEMAFKVAGSLAFKKAMETAKVVLLEPMMNMKVTVPEETMGDVIGDLNSRRGKVVGVEPKANSQII
RAVVPMSEVLAYANDLKSMTSDRGLFTMEFSHYEEVPTHLAQKVVAESQKAEGKNNH
>Mature_696_residues
GKYDTAKLRNLGIVAHGGAGKTSLTEAILYTAGMIDRLGRVDDGTSTMDFEPEEIKRKITISSSLDHCEWNGHSLHIVDT
PGYGNFIADTRACMRALGGCVVILSAISGVKVQTEEVWEWANEFELPRIAFVNKMDREYANFLRAIDDMEKSLKARGVAV
QMPLGAAETFEGVIDLITMKAYRYAKDTSGTFKEEEIPAEYRDEAQRLREHLVETVAEAYDGLTEKYLETGELTEEEILD
GLRVGTLRYTFTPVFCGSATMNIGVRHLLDYICACLPSPQDRGAVAGANPKNGEPIERRPEESEPFSALVFKTTSDPYTG
KISIFRVYSGVLNSDSTIYNPVRECEERIGQIYELEGKKQKPIKQAVAGDIVAVAKLKETLTGDTLCDKDHPIIYEPAKP
LQPVISYAVQPKTKNDEDKIHGALQRLMEEDQTIQVRRDEKTRELILSGMGQVHLEVTIEKLKRKFNVDVEMKTQKVPYL
ETFKAQVKAQGKYKKQSGGRGQYGDCWVEFSPLGRGDGFQFEDKIVGGVIPRQYIPAVEKGIFEASQDGFLAGYPLVDFK
AAVYDGSFHTVDSSEMAFKVAGSLAFKKAMETAKVVLLEPMMNMKVTVPEETMGDVIGDLNSRRGKVVGVEPKANSQIIR
AVVPMSEVLAYANDLKSMTSDRGLFTMEFSHYEEVPTHLAQKVVAESQKAEGKNNH

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=699, Percent_Identity=34.0486409155937, Blast_Score=401, Evalue=1e-111,
Organism=Homo sapiens, GI19923640, Length=708, Percent_Identity=30.3672316384181, Blast_Score=326, Evalue=4e-89,
Organism=Homo sapiens, GI25306283, Length=392, Percent_Identity=34.9489795918367, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI25306287, Length=289, Percent_Identity=37.3702422145329, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI4503483, Length=856, Percent_Identity=22.0794392523364, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI157426893, Length=156, Percent_Identity=28.8461538461538, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI94966754, Length=138, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1789738, Length=692, Percent_Identity=45.8092485549133, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1790835, Length=486, Percent_Identity=25.5144032921811, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI48994988, Length=173, Percent_Identity=30.635838150289, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17533571, Length=702, Percent_Identity=32.1937321937322, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17556745, Length=710, Percent_Identity=25.4929577464789, Blast_Score=244, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6323098, Length=697, Percent_Identity=33.428981348637, Blast_Score=398, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322359, Length=790, Percent_Identity=27.4683544303797, Blast_Score=286, Evalue=8e-78,
Organism=Saccharomyces cerevisiae, GI6324707, Length=167, Percent_Identity=26.9461077844311, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320593, Length=167, Percent_Identity=26.9461077844311, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24582462, Length=699, Percent_Identity=32.761087267525, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI221458488, Length=725, Percent_Identity=25.9310344827586, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24585709, Length=150, Percent_Identity=31.3333333333333, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585711, Length=150, Percent_Identity=31.3333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585713, Length=150, Percent_Identity=31.3333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI78706572, Length=177, Percent_Identity=25.9887005649718, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 77464; Mature: 77333

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKYDTAKLRNLGIVAHGGAGKTSLTEAILYTAGMIDRLGRVDDGTSTMDFEPEEIKRKI
CCCCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHEE
TISSSLDHCEWNGHSLHIVDTPGYGNFIADTRACMRALGGCVVILSAISGVKVQTEEVWE
EECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH
WANEFELPRIAFVNKMDREYANFLRAIDDMEKSLKARGVAVQMPLGAAETFEGVIDLITM
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHH
KAYRYAKDTSGTFKEEEIPAEYRDEAQRLREHLVETVAEAYDGLTEKYLETGELTEEEIL
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
DGLRVGTLRYTFTPVFCGSATMNIGVRHLLDYICACLPSPQDRGAVAGANPKNGEPIERR
CCHHCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PEESEPFSALVFKTTSDPYTGKISIFRVYSGVLNSDSTIYNPVRECEERIGQIYELEGKK
CCCCCCCEEEEEEECCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHCCEEECCCCC
QKPIKQAVAGDIVAVAKLKETLTGDTLCDKDHPIIYEPAKPLQPVISYAVQPKTKNDEDK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCCHHH
IHGALQRLMEEDQTIQVRRDEKTRELILSGMGQVHLEVTIEKLKRKFNVDVEMKTQKVPY
HHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCEEEECCCCCH
LETFKAQVKAQGKYKKQSGGRGQYGDCWVEFSPLGRGDGFQFEDKIVGGVIPRQYIPAVE
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHH
KGIFEASQDGFLAGYPLVDFKAAVYDGSFHTVDSSEMAFKVAGSLAFKKAMETAKVVLLE
HHHHHCCCCCCEECCCHHHCCCEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEE
PMMNMKVTVPEETMGDVIGDLNSRRGKVVGVEPKANSQIIRAVVPMSEVLAYANDLKSMT
CCCCCEEECCHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHH
SDRGLFTMEFSHYEEVPTHLAQKVVAESQKAEGKNNH
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKYDTAKLRNLGIVAHGGAGKTSLTEAILYTAGMIDRLGRVDDGTSTMDFEPEEIKRKI
CCCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHEE
TISSSLDHCEWNGHSLHIVDTPGYGNFIADTRACMRALGGCVVILSAISGVKVQTEEVWE
EECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH
WANEFELPRIAFVNKMDREYANFLRAIDDMEKSLKARGVAVQMPLGAAETFEGVIDLITM
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHH
KAYRYAKDTSGTFKEEEIPAEYRDEAQRLREHLVETVAEAYDGLTEKYLETGELTEEEIL
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
DGLRVGTLRYTFTPVFCGSATMNIGVRHLLDYICACLPSPQDRGAVAGANPKNGEPIERR
CCHHCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PEESEPFSALVFKTTSDPYTGKISIFRVYSGVLNSDSTIYNPVRECEERIGQIYELEGKK
CCCCCCCEEEEEEECCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHCCEEECCCCC
QKPIKQAVAGDIVAVAKLKETLTGDTLCDKDHPIIYEPAKPLQPVISYAVQPKTKNDEDK
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCCHHH
IHGALQRLMEEDQTIQVRRDEKTRELILSGMGQVHLEVTIEKLKRKFNVDVEMKTQKVPY
HHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCEEEECCCCCH
LETFKAQVKAQGKYKKQSGGRGQYGDCWVEFSPLGRGDGFQFEDKIVGGVIPRQYIPAVE
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHHHHH
KGIFEASQDGFLAGYPLVDFKAAVYDGSFHTVDSSEMAFKVAGSLAFKKAMETAKVVLLE
HHHHHCCCCCCEECCCHHHCCCEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEE
PMMNMKVTVPEETMGDVIGDLNSRRGKVVGVEPKANSQIIRAVVPMSEVLAYANDLKSMT
CCCCCEEECCHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHH
SDRGLFTMEFSHYEEVPTHLAQKVVAESQKAEGKNNH
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA