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The map label for this gene is yhdN [H]

Identifier: 39996472

GI number: 39996472

Start: 1498229

End: 1499281

Strand: Reverse

Name: yhdN [H]

Synonym: GSU1370

Alternate gene names: 39996472

Gene position: 1499281-1498229 (Counterclockwise)

Preceding gene: 39996473

Following gene: 39996444

Centisome position: 39.31

GC content: 64.01

Gene sequence:

>1053_bases
ATGAAATACCTGCCGCTCGGTTCGACCGGGCTGACCGTTTCGGAATGCGGCTTCGGCTGCATCCCCATCATCCGCCTGCC
CCAGGACGAAGCGGTCCGGGTCCTCCGGCACGCCTTCGACCGGGGGATCACCTTCTTCGACACGGCCAACGCCTATCGCG
ACAGCGAAGAGAAGATGGGGATCGCCTTTGCCGGCATCCGCCACAAGCTGGTCATCGCCACCAAGAGCCTGCTGCGGAGC
GCCGAGGGCGTAACCGGCCACGTGGAGAACAGCCTCCGGAAGCTGGGCACCGATTACCTGGACCTCTACCAGCTGCACCA
GATCGCCCAGGAAAAGGACTGGGCCGAGGTCACGGGCCCGTCGGGCGCGCTGGAAGCGGCCATGGCCGCCAAGGCCGCCG
GCAAGGTCAGGCACGTGGGGGTCACCTCCCATAACCTGGAGATGGCCCTCAAGCTGGTCCGCACCGGCCTGTTCGACACG
ATCCAGTTCCCCTTCAACCTGATCGAGGAAGGGGCCAAGGATGAACTGCTCGGCGCGGCCCGCGACGCGGGCATGGCCTT
CATCTGCATGAAACCGTTCGGGGGCGGCGTGATCGACAATGCCGCCGTGGCCTTTACCTACCTCCGCAGCCACGACGGCA
TCTTCCCGATCCCGGGATTCGAGTCCTGCGCCCAGGTGGACGAAGTCCTTTCATTTTACGAACGCGACAACGTCGTCACC
GAGCAGGACCTGGCAATCATGGAACAGTACCGCCGCGAACTGGGCAAACGGTTCTGCCGCCGCTGCGAATACTGCCAGCC
CTGCCCCCAGGGGGTGATGATCACCCCGGCCATGGGCTACCCGATCGTTGCCTCGCGCATGTCGCCGGCCGTTGCGGCGG
AATTCTGCAGCAAAGCCATGGAAACGGTGCCCCTCTGCACCGAATGCGGGGCATGCATCGCGCGCTGTCCGTACGAATTG
CCGATCAGCGACATTCTCAAGGCGAATTATGCGATGTACCGGGGGCATGTGGCGGGGAGTCAGGGGGGATTTGCAGGTGG
TAAATCTTCGTAA

Upstream 100 bases:

>100_bases
TGCCAACAGGCGCGCCTCGCTTCCCCGCTCGCGGGTGCCGGGCGTTCAGCCCTCCTCGCCACCTGTTGCACAAACCTGGT
CCTTAGTTCGAGGTGACCCG

Downstream 100 bases:

>100_bases
CTGACGAATCATGGCGACAAGCTGCTGAAACAAGCCGGCTGCCGGACAAAATGCTCACTTGCGGCACCGTATGCGTTCTC
GTCGGCCGGCAGGATGGTGT

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKYLPLGSTGLTVSECGFGCIPIIRLPQDEAVRVLRHAFDRGITFFDTANAYRDSEEKMGIAFAGIRHKLVIATKSLLRS
AEGVTGHVENSLRKLGTDYLDLYQLHQIAQEKDWAEVTGPSGALEAAMAAKAAGKVRHVGVTSHNLEMALKLVRTGLFDT
IQFPFNLIEEGAKDELLGAARDAGMAFICMKPFGGGVIDNAAVAFTYLRSHDGIFPIPGFESCAQVDEVLSFYERDNVVT
EQDLAIMEQYRRELGKRFCRRCEYCQPCPQGVMITPAMGYPIVASRMSPAVAAEFCSKAMETVPLCTECGACIARCPYEL
PISDILKANYAMYRGHVAGSQGGFAGGKSS

Sequences:

>Translated_350_residues
MKYLPLGSTGLTVSECGFGCIPIIRLPQDEAVRVLRHAFDRGITFFDTANAYRDSEEKMGIAFAGIRHKLVIATKSLLRS
AEGVTGHVENSLRKLGTDYLDLYQLHQIAQEKDWAEVTGPSGALEAAMAAKAAGKVRHVGVTSHNLEMALKLVRTGLFDT
IQFPFNLIEEGAKDELLGAARDAGMAFICMKPFGGGVIDNAAVAFTYLRSHDGIFPIPGFESCAQVDEVLSFYERDNVVT
EQDLAIMEQYRRELGKRFCRRCEYCQPCPQGVMITPAMGYPIVASRMSPAVAAEFCSKAMETVPLCTECGACIARCPYEL
PISDILKANYAMYRGHVAGSQGGFAGGKSS
>Mature_350_residues
MKYLPLGSTGLTVSECGFGCIPIIRLPQDEAVRVLRHAFDRGITFFDTANAYRDSEEKMGIAFAGIRHKLVIATKSLLRS
AEGVTGHVENSLRKLGTDYLDLYQLHQIAQEKDWAEVTGPSGALEAAMAAKAAGKVRHVGVTSHNLEMALKLVRTGLFDT
IQFPFNLIEEGAKDELLGAARDAGMAFICMKPFGGGVIDNAAVAFTYLRSHDGIFPIPGFESCAQVDEVLSFYERDNVVT
EQDLAIMEQYRRELGKRFCRRCEYCQPCPQGVMITPAMGYPIVASRMSPAVAAEFCSKAMETVPLCTECGACIARCPYEL
PISDILKANYAMYRGHVAGSQGGFAGGKSS

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081735, Length=223, Percent_Identity=32.2869955156951, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788070, Length=285, Percent_Identity=24.9122807017544, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788081, Length=249, Percent_Identity=27.3092369477912, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24646155, Length=221, Percent_Identity=30.316742081448, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38105; Mature: 38105

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLPLGSTGLTVSECGFGCIPIIRLPQDEAVRVLRHAFDRGITFFDTANAYRDSEEKMG
CCCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCHHHCCCHHHCC
IAFAGIRHKLVIATKSLLRSAEGVTGHVENSLRKLGTDYLDLYQLHQIAQEKDWAEVTGP
EEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHCCC
SGALEAAMAAKAAGKVRHVGVTSHNLEMALKLVRTGLFDTIQFPFNLIEEGAKDELLGAA
CHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RDAGMAFICMKPFGGGVIDNAAVAFTYLRSHDGIFPIPGFESCAQVDEVLSFYERDNVVT
HCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EQDLAIMEQYRRELGKRFCRRCEYCQPCPQGVMITPAMGYPIVASRMSPAVAAEFCSKAM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHCCHHHHHHHHHHHH
ETVPLCTECGACIARCPYELPISDILKANYAMYRGHVAGSQGGFAGGKSS
HHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKYLPLGSTGLTVSECGFGCIPIIRLPQDEAVRVLRHAFDRGITFFDTANAYRDSEEKMG
CCCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCHHHCCCHHHCC
IAFAGIRHKLVIATKSLLRSAEGVTGHVENSLRKLGTDYLDLYQLHQIAQEKDWAEVTGP
EEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHCCC
SGALEAAMAAKAAGKVRHVGVTSHNLEMALKLVRTGLFDTIQFPFNLIEEGAKDELLGAA
CHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RDAGMAFICMKPFGGGVIDNAAVAFTYLRSHDGIFPIPGFESCAQVDEVLSFYERDNVVT
HCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EQDLAIMEQYRRELGKRFCRRCEYCQPCPQGVMITPAMGYPIVASRMSPAVAAEFCSKAM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHCCHHHHHHHHHHHH
ETVPLCTECGACIARCPYELPISDILKANYAMYRGHVAGSQGGFAGGKSS
HHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]