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The map label for this gene is namA [H]

Identifier: 39996473

GI number: 39996473

Start: 1499442

End: 1500539

Strand: Reverse

Name: namA [H]

Synonym: GSU1371

Alternate gene names: 39996473

Gene position: 1500539-1499442 (Counterclockwise)

Preceding gene: 39996474

Following gene: 39996472

Centisome position: 39.34

GC content: 70.22

Gene sequence:

>1098_bases
ATGTCACATCTCTTCGAACCCTTGACCATACGCAGCCTGACCCTGCCCAACCGCATCGCCGTATCCCCCATGTGCATGTA
TTCCAGCGAAGACGGCTTTGCCAACGACTGGCACCTGGTCCACCTGGGCAGCCGCGCGGCCGGCGGCGCCGGCCTGGTGC
TGACCGAGGCCACCGCCGTCACCCCCCAGGGGCGGATCAGTCCCCGGGACCTCGGCATCTGGCGCGACGAGCACATCGAA
TTTCTGGCCCGCATCGTCCACTTCATCACCCAGCGCGGCAGCACCGCCGGCATTCAGCTGGCCCATGCCGGCCGCAAGGC
GAGCACCCCGGCCCCGTGGGAACAGCGGACCGCCACCCTGTCCGGGGCCGAAGGAGGCTGGCCCATCGTGGCCCCCAGCC
CCATCCCCTTTGACGAGGGGTGCATCGTACCGCAGGAACTGAGCACCGGGGAGATCGACGCCATCACGGCGGCCTTCGTG
GACGCGGCCCGCCGCTCCCTGCTGGCCGGGTTCCAGATCGCCGAGATCCACGCGGCCCACGGCTACCTGCTGCACCAGTT
CCTCTCGCCCCTCAGCAACCAGCGCACCGACCAGTACGGCGGCAGCTTCGAAAACCGCACCCGGCTGCTCCGGACCGTCG
TTACCGCGGTCAGGGAAGTCTGGCCCGAGCACCTGCCGCTCTGGGTCAGGATCTCGGCCACCGACTGGGTCGACGGGGGC
TGGGACATCGAGCAGTCGGTGGAACTGGTGCGCCGGCTCCTGCCGCTGGGGGTCGATCTGATCGACTGCTCGTCCGGCGG
CAGCGCCCCCCATGCCCGGATTCCCCTGGGCGCCGGCTACCAGACCCAGTTTGCCGAGCGGATCAGGCGGGAGACCGGCG
GCAGGACCGGGTCGGTGGGCCAGATCACGGCACCGGCCCAGGCGGACCACATCATCCGCTCCGGCCAGGCCGACCTGGTG
CTGCTGGCCCGGGAGCTGCTGCGCGATCCCTACTGGCCCCTCAGGGCGGCCCGGGAGTTGGGGCATCAGTCCCCCTGGCC
CGCCCAGTATGTCCGGGCCGCGCCGCACAATACACCGGCCTATCTGCCGAAGGACTGA

Upstream 100 bases:

>100_bases
CCATTCCTGCCGGGGCAGCTCCCGGTTCGCAACGGTGAATTCGGTGCTATGCTGTAACCAGGGCACCGGACCCATGAACC
ACCAGCCAAGGAGGCACGCC

Downstream 100 bases:

>100_bases
GCCGTGAACCGCACGCGAAACTACCGCAGGGCCGGTTGCCGCCTGCCCAACAACTCAACGTGCCAACAGGCGCGCCTCGC
TTCCCCGCTCGCGGGTGCCG

Product: oxidoreductase, FAD/FMN-binding

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSHLFEPLTIRSLTLPNRIAVSPMCMYSSEDGFANDWHLVHLGSRAAGGAGLVLTEATAVTPQGRISPRDLGIWRDEHIE
FLARIVHFITQRGSTAGIQLAHAGRKASTPAPWEQRTATLSGAEGGWPIVAPSPIPFDEGCIVPQELSTGEIDAITAAFV
DAARRSLLAGFQIAEIHAAHGYLLHQFLSPLSNQRTDQYGGSFENRTRLLRTVVTAVREVWPEHLPLWVRISATDWVDGG
WDIEQSVELVRRLLPLGVDLIDCSSGGSAPHARIPLGAGYQTQFAERIRRETGGRTGSVGQITAPAQADHIIRSGQADLV
LLARELLRDPYWPLRAARELGHQSPWPAQYVRAAPHNTPAYLPKD

Sequences:

>Translated_365_residues
MSHLFEPLTIRSLTLPNRIAVSPMCMYSSEDGFANDWHLVHLGSRAAGGAGLVLTEATAVTPQGRISPRDLGIWRDEHIE
FLARIVHFITQRGSTAGIQLAHAGRKASTPAPWEQRTATLSGAEGGWPIVAPSPIPFDEGCIVPQELSTGEIDAITAAFV
DAARRSLLAGFQIAEIHAAHGYLLHQFLSPLSNQRTDQYGGSFENRTRLLRTVVTAVREVWPEHLPLWVRISATDWVDGG
WDIEQSVELVRRLLPLGVDLIDCSSGGSAPHARIPLGAGYQTQFAERIRRETGGRTGSVGQITAPAQADHIIRSGQADLV
LLARELLRDPYWPLRAARELGHQSPWPAQYVRAAPHNTPAYLPKD
>Mature_364_residues
SHLFEPLTIRSLTLPNRIAVSPMCMYSSEDGFANDWHLVHLGSRAAGGAGLVLTEATAVTPQGRISPRDLGIWRDEHIEF
LARIVHFITQRGSTAGIQLAHAGRKASTPAPWEQRTATLSGAEGGWPIVAPSPIPFDEGCIVPQELSTGEIDAITAAFVD
AARRSLLAGFQIAEIHAAHGYLLHQFLSPLSNQRTDQYGGSFENRTRLLRTVVTAVREVWPEHLPLWVRISATDWVDGGW
DIEQSVELVRRLLPLGVDLIDCSSGGSAPHARIPLGAGYQTQFAERIRRETGGRTGSVGQITAPAQADHIIRSGQADLVL
LARELLRDPYWPLRAARELGHQSPWPAQYVRAAPHNTPAYLPKD

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=356, Percent_Identity=30.3370786516854, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789463, Length=337, Percent_Identity=27.0029673590504, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=308, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI72001454, Length=307, Percent_Identity=28.6644951140065, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=320, Percent_Identity=26.25, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=228, Percent_Identity=29.8245614035088, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=262, Percent_Identity=28.2442748091603, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=229, Percent_Identity=27.5109170305677, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17566914, Length=283, Percent_Identity=29.3286219081272, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=321, Percent_Identity=28.6604361370716, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6325086, Length=321, Percent_Identity=28.3489096573209, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39926; Mature: 39794

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLFEPLTIRSLTLPNRIAVSPMCMYSSEDGFANDWHLVHLGSRAAGGAGLVLTEATAV
CCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEEECEEE
TPQGRISPRDLGIWRDEHIEFLARIVHFITQRGSTAGIQLAHAGRKASTPAPWEQRTATL
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHEEE
SGAEGGWPIVAPSPIPFDEGCIVPQELSTGEIDAITAAFVDAARRSLLAGFQIAEIHAAH
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GYLLHQFLSPLSNQRTDQYGGSFENRTRLLRTVVTAVREVWPEHLPLWVRISATDWVDGG
HHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHCHHHCCEEEEEECCCCCCCC
WDIEQSVELVRRLLPLGVDLIDCSSGGSAPHARIPLGAGYQTQFAERIRRETGGRTGSVG
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
QITAPAQADHIIRSGQADLVLLARELLRDPYWPLRAARELGHQSPWPAQYVRAAPHNTPA
EEECCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCC
YLPKD
CCCCC
>Mature Secondary Structure 
SHLFEPLTIRSLTLPNRIAVSPMCMYSSEDGFANDWHLVHLGSRAAGGAGLVLTEATAV
CCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEEECEEE
TPQGRISPRDLGIWRDEHIEFLARIVHFITQRGSTAGIQLAHAGRKASTPAPWEQRTATL
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHEEE
SGAEGGWPIVAPSPIPFDEGCIVPQELSTGEIDAITAAFVDAARRSLLAGFQIAEIHAAH
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GYLLHQFLSPLSNQRTDQYGGSFENRTRLLRTVVTAVREVWPEHLPLWVRISATDWVDGG
HHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHHHCHHHCCEEEEEECCCCCCCC
WDIEQSVELVRRLLPLGVDLIDCSSGGSAPHARIPLGAGYQTQFAERIRRETGGRTGSVG
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
QITAPAQADHIIRSGQADLVLLARELLRDPYWPLRAARELGHQSPWPAQYVRAAPHNTPA
EEECCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCC
YLPKD
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA