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The map label for this gene is coaD

Identifier: 39996345

GI number: 39996345

Start: 1345453

End: 1345947

Strand: Reverse

Name: coaD

Synonym: GSU1243

Alternate gene names: 39996345

Gene position: 1345947-1345453 (Counterclockwise)

Preceding gene: 39996346

Following gene: 39996344

Centisome position: 35.29

GC content: 59.8

Gene sequence:

>495_bases
ATGCCGACCAAGATTGCCGTCTACCCCGGCTCATTCGACCCGATCACCTACGGTCACCTGGACATCATCGACCGCGCACT
CAGGATATTCGACCAAGTCATCGTTGCGGTGGCCCGCAACTCGGCCAAATCGGCCCTGTTCACCACCGACGAGCGGGTCG
ACATGATCCAGCGGGTGCTGGCCGACAACGTCAGGGCCAGGGTTGACACTTTCGACGGCCTTCTGATAGATTACGTCCTC
TCCCAGAAGGCAACGGTCATTATCCGGGGCCTGCGGGCCATTTCCGACTTCGAGTACGAGTTCCAGATCGCCCAGATGAA
CCGAAGCATCTCCCAGGATGTGGAGACCCTCTTCATGATGACCTCGGTTCCCTACGGCTATCTTTCCTCCTCCATCGTGA
AGGAGGTGAGCTCCCTGAACGGCCCCATCGACGGACTGGTGCCGCCGCTGGTCCGCCAGGCGCTCAGGGACAAATTCGCA
GGACCAGATCGTTAG

Upstream 100 bases:

>100_bases
CGAGGTACTACCCGACCTCATGGAACCGCTCCACTTGGTTGACCGGCGGATCTACGGCGATACCGCCCTCTCATTCTTCC
GGAAAAGGAACTGAACGCCC

Downstream 100 bases:

>100_bases
TGTCCCATTCGGACATTTCCATCACCCCCAAGGAGGGTACAATGAAACTTGCAGACCGCGTCAACAAGATCCAGCCTTCC
CCCACCCTGTCCATCGATGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MPTKIAVYPGSFDPITYGHLDIIDRALRIFDQVIVAVARNSAKSALFTTDERVDMIQRVLADNVRARVDTFDGLLIDYVL
SQKATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMMTSVPYGYLSSSIVKEVSSLNGPIDGLVPPLVRQALRDKFA
GPDR

Sequences:

>Translated_164_residues
MPTKIAVYPGSFDPITYGHLDIIDRALRIFDQVIVAVARNSAKSALFTTDERVDMIQRVLADNVRARVDTFDGLLIDYVL
SQKATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMMTSVPYGYLSSSIVKEVSSLNGPIDGLVPPLVRQALRDKFA
GPDR
>Mature_163_residues
PTKIAVYPGSFDPITYGHLDIIDRALRIFDQVIVAVARNSAKSALFTTDERVDMIQRVLADNVRARVDTFDGLLIDYVLS
QKATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMMTSVPYGYLSSSIVKEVSSLNGPIDGLVPPLVRQALRDKFAG
PDR

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=45.859872611465, Blast_Score=154, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_GEOSL (Q74DS2)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952296.1
- ProteinModelPortal:   Q74DS2
- SMR:   Q74DS2
- GeneID:   2688194
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1243
- NMPDR:   fig|243231.1.peg.1234
- TIGR:   GSU1243
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   GSUL243231:GSU_1243-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18330; Mature: 18199

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTKIAVYPGSFDPITYGHLDIIDRALRIFDQVIVAVARNSAKSALFTTDERVDMIQRVL
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHH
ADNVRARVDTFDGLLIDYVLSQKATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMM
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TSVPYGYLSSSIVKEVSSLNGPIDGLVPPLVRQALRDKFAGPDR
HHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PTKIAVYPGSFDPITYGHLDIIDRALRIFDQVIVAVARNSAKSALFTTDERVDMIQRVL
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHH
ADNVRARVDTFDGLLIDYVLSQKATVIIRGLRAISDFEYEFQIAQMNRSISQDVETLFMM
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TSVPYGYLSSSIVKEVSSLNGPIDGLVPPLVRQALRDKFAGPDR
HHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA