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The map label for this gene is aatA [H]

Identifier: 39996344

GI number: 39996344

Start: 1344212

End: 1345411

Strand: Reverse

Name: aatA [H]

Synonym: GSU1242

Alternate gene names: 39996344

Gene position: 1345411-1344212 (Counterclockwise)

Preceding gene: 39996345

Following gene: 39996343

Centisome position: 35.27

GC content: 60.25

Gene sequence:

>1200_bases
ATGAAACTTGCAGACCGCGTCAACAAGATCCAGCCTTCCCCCACCCTGTCCATCGATGCCAAGGCAAAGGCACTGAAGGC
TCAGGGCATCGACGTTGTCGGCTTCGGTGCCGGCGAGCCCGATTTCGACACCCCGGCCAACATCAAGGAAGCCGGCAAGA
AAGCCATCGACGCAGGTTTCACCAAATACATGCCGGTGGGCGGCGCCGATGATCTGAAAGATGCCATCATCGCCAAAATG
AAGCGCGATCACGGGCTGGAGTACACCCGCGACGAGATTTCCGTCGCCTGCGGCGCCAAGCACACCCTCTACAACATCTC
CCAGGCCCTGATCCAGGAGGGAGACGAAGTCATCATCCCTGGTCCCTACTGGGTCTCCTACCCGGACCAGATCGTGCTGG
CCGGCGGCACGCCGGTGTTCATCATGACCGACGAGTCCACCGGGTTCAAGATCACGGCCGAGCAGCTGGAAAAAGCCATC
ACCCCCCGGACCGTCTACGTGATCCTCAACTCCCCCTGCAACCCGACCGGCTCCACCTACACCAAGGATGAGCTGAAGGC
GCTGGCCGCGGTGCTGCTCAAGCACCCCCACGTCTATGTGGTTTCCGACGACATCTACGAGAAGCTCCTCTATGACGGGC
TCGAGTTCTGCAATATCCCCATGGCCTGCCCGGAGCTCAAGGACCGTACCATCATCGTAAACGGCGTCTCCAAAGCTTAC
TCCATGACCGGCTGGCGGATCGGCTACGCCTGCGGCCCCAAGGCGCTCATGGCCGCCATGACCAAGATGCAGTCCCAGTC
CACCTCCAATGCCACCTCCATCGCCCAGAAGGCCTCCGTAGAGGCACTGAACGGACCCCAGGAGCCCGTGGCCGAGATGG
TCAAGGAATTCGAAAAACGCCGCACCTACATCGTCGACCGGCTCAATGCCATTCCGGGGGTCACCTGCTTCAAGTCCACC
GGTGCCTTCTATGCCTTCCCCAACTTCTCCGGCGTGTACGGCAAGACCACCCCGGCCGGCAAGAAGATTGAGAATTCTTC
CGACTTTGCCGCTTATCTGCTTGAAGACGCCAAAGTGGCGTTGGTTCCCGGCATCGCATTCGGGGACGACCGCTACGCCC
GCCTCTCCTACGCCACAAGCCTGGAGACCATCAAGAAGGGACTCGATCGGATCGAGGAAGCGATAGGCAATCTCAAGTAA

Upstream 100 bases:

>100_bases
TGGTGCCGCCGCTGGTCCGCCAGGCGCTCAGGGACAAATTCGCAGGACCAGATCGTTAGTGTCCCATTCGGACATTTCCA
TCACCCCCAAGGAGGGTACA

Downstream 100 bases:

>100_bases
GGATTCACACCGGTGTTGCGTCGGAGCGCAACCCTGCTATTGTTGGAAAAAAGGCGAGGATGACAGCTCCATCCTCGCCT
TTTTTATTGTACGAACGTGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKLADRVNKIQPSPTLSIDAKAKALKAQGIDVVGFGAGEPDFDTPANIKEAGKKAIDAGFTKYMPVGGADDLKDAIIAKM
KRDHGLEYTRDEISVACGAKHTLYNISQALIQEGDEVIIPGPYWVSYPDQIVLAGGTPVFIMTDESTGFKITAEQLEKAI
TPRTVYVILNSPCNPTGSTYTKDELKALAAVLLKHPHVYVVSDDIYEKLLYDGLEFCNIPMACPELKDRTIIVNGVSKAY
SMTGWRIGYACGPKALMAAMTKMQSQSTSNATSIAQKASVEALNGPQEPVAEMVKEFEKRRTYIVDRLNAIPGVTCFKST
GAFYAFPNFSGVYGKTTPAGKKIENSSDFAAYLLEDAKVALVPGIAFGDDRYARLSYATSLETIKKGLDRIEEAIGNLK

Sequences:

>Translated_399_residues
MKLADRVNKIQPSPTLSIDAKAKALKAQGIDVVGFGAGEPDFDTPANIKEAGKKAIDAGFTKYMPVGGADDLKDAIIAKM
KRDHGLEYTRDEISVACGAKHTLYNISQALIQEGDEVIIPGPYWVSYPDQIVLAGGTPVFIMTDESTGFKITAEQLEKAI
TPRTVYVILNSPCNPTGSTYTKDELKALAAVLLKHPHVYVVSDDIYEKLLYDGLEFCNIPMACPELKDRTIIVNGVSKAY
SMTGWRIGYACGPKALMAAMTKMQSQSTSNATSIAQKASVEALNGPQEPVAEMVKEFEKRRTYIVDRLNAIPGVTCFKST
GAFYAFPNFSGVYGKTTPAGKKIENSSDFAAYLLEDAKVALVPGIAFGDDRYARLSYATSLETIKKGLDRIEEAIGNLK
>Mature_399_residues
MKLADRVNKIQPSPTLSIDAKAKALKAQGIDVVGFGAGEPDFDTPANIKEAGKKAIDAGFTKYMPVGGADDLKDAIIAKM
KRDHGLEYTRDEISVACGAKHTLYNISQALIQEGDEVIIPGPYWVSYPDQIVLAGGTPVFIMTDESTGFKITAEQLEKAI
TPRTVYVILNSPCNPTGSTYTKDELKALAAVLLKHPHVYVVSDDIYEKLLYDGLEFCNIPMACPELKDRTIIVNGVSKAY
SMTGWRIGYACGPKALMAAMTKMQSQSTSNATSIAQKASVEALNGPQEPVAEMVKEFEKRRTYIVDRLNAIPGVTCFKST
GAFYAFPNFSGVYGKTTPAGKKIENSSDFAAYLLEDAKVALVPGIAFGDDRYARLSYATSLETIKKGLDRIEEAIGNLK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=27.1794871794872, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=27.1794871794872, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI95147551, Length=384, Percent_Identity=24.4791666666667, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI169881279, Length=384, Percent_Identity=24.4791666666667, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI169881281, Length=295, Percent_Identity=22.3728813559322, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4507369, Length=375, Percent_Identity=21.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=27.1505376344086, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1788722, Length=408, Percent_Identity=29.1666666666667, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788627, Length=359, Percent_Identity=28.6908077994429, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=199, Percent_Identity=31.1557788944724, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=199, Percent_Identity=31.1557788944724, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=402, Percent_Identity=25.6218905472637, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17567663, Length=347, Percent_Identity=26.5129682997118, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71981209, Length=321, Percent_Identity=22.7414330218069, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=362, Percent_Identity=26.7955801104972, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=348, Percent_Identity=23.2758620689655, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28573069, Length=292, Percent_Identity=26.7123287671233, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646114, Length=292, Percent_Identity=26.7123287671233, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573067, Length=292, Percent_Identity=26.7123287671233, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573065, Length=292, Percent_Identity=26.7123287671233, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI18859735, Length=318, Percent_Identity=21.0691823899371, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45551451, Length=327, Percent_Identity=27.217125382263, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641770, Length=327, Percent_Identity=27.217125382263, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641760, Length=327, Percent_Identity=27.217125382263, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641768, Length=327, Percent_Identity=27.217125382263, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641766, Length=327, Percent_Identity=27.217125382263, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641764, Length=327, Percent_Identity=27.217125382263, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43254; Mature: 43254

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLADRVNKIQPSPTLSIDAKAKALKAQGIDVVGFGAGEPDFDTPANIKEAGKKAIDAGF
CCHHHHHHHCCCCCCEEECCHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
TKYMPVGGADDLKDAIIAKMKRDHGLEYTRDEISVACGAKHTLYNISQALIQEGDEVIIP
HHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEC
GPYWVSYPDQIVLAGGTPVFIMTDESTGFKITAEQLEKAITPRTVYVILNSPCNPTGSTY
CCEEECCCCEEEEECCCEEEEEECCCCCCEEEHHHHHHHCCCEEEEEEECCCCCCCCCCC
TKDELKALAAVLLKHPHVYVVSDDIYEKLLYDGLEFCNIPMACPELKDRTIIVNGVSKAY
CHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEECCHHHH
SMTGWRIGYACGPKALMAAMTKMQSQSTSNATSIAQKASVEALNGPQEPVAEMVKEFEKR
HCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RTYIVDRLNAIPGVTCFKSTGAFYAFPNFSGVYGKTTPAGKKIENSSDFAAYLLEDAKVA
HHHHHHHHHCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEE
LVPGIAFGDDRYARLSYATSLETIKKGLDRIEEAIGNLK
EECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLADRVNKIQPSPTLSIDAKAKALKAQGIDVVGFGAGEPDFDTPANIKEAGKKAIDAGF
CCHHHHHHHCCCCCCEEECCHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
TKYMPVGGADDLKDAIIAKMKRDHGLEYTRDEISVACGAKHTLYNISQALIQEGDEVIIP
HHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEC
GPYWVSYPDQIVLAGGTPVFIMTDESTGFKITAEQLEKAITPRTVYVILNSPCNPTGSTY
CCEEECCCCEEEEECCCEEEEEECCCCCCEEEHHHHHHHCCCEEEEEEECCCCCCCCCCC
TKDELKALAAVLLKHPHVYVVSDDIYEKLLYDGLEFCNIPMACPELKDRTIIVNGVSKAY
CHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEECCHHHH
SMTGWRIGYACGPKALMAAMTKMQSQSTSNATSIAQKASVEALNGPQEPVAEMVKEFEKR
HCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RTYIVDRLNAIPGVTCFKSTGAFYAFPNFSGVYGKTTPAGKKIENSSDFAAYLLEDAKVA
HHHHHHHHHCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEE
LVPGIAFGDDRYARLSYATSLETIKKGLDRIEEAIGNLK
EECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA