Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 39996001

GI number: 39996001

Start: 960231

End: 961613

Strand: Reverse

Name: tldD [H]

Synonym: GSU0896

Alternate gene names: 39996001

Gene position: 961613-960231 (Counterclockwise)

Preceding gene: 39996005

Following gene: 39996000

Centisome position: 25.21

GC content: 63.05

Gene sequence:

>1383_bases
ATGCTCGACCAGATGAACCTATCCGCCATCCTGCGACAGGCCCTCGCGGGCGGCGGTGAATTCGCGGAGATTTACTTCGA
AGAAGGCTCCACCACCGCAGTATTCTGCGAGGACGGAAAAATCGAGAAGGTCCTCGCCGGAACGGACCGCGGGGTGGGGA
TCCGGGTCATTTCCGATCTCCGCACCGCCTACGCGTACACCAACGAGGTGACCGGCACCGCCCTCATGGAACTGGCCACA
ACGGTGAGCAGGGCAGTGCGGGGCAAGGTCTTTGAGCAGACCATCGCAATGAAACCGAGGGCAGTGGGGGCAGGGTTCCC
CATAGAAATTACGCCAGATGGCGTAGCTCTCCATGAAAAAATTGCACTGGTGGAGAGAGGCAACAAGGCTGCCCGCGACA
TCAGCGAAACAATTCGGCAAGTTACAATTGCCTATCGCGACAGCCGAGTGAAATGCCAGATCGCCAATTCACTGGGCGAC
TTCATCGAAACCAATCGGACGGGCACCCTGTACCTGGCCCATGTGGTTGCTGCTGGCGCGGACGTGATCCAGACCGGCTA
TGAAGCAACGGGGAAATTCATGGGCCACGAGATCTTCCGGGAGCGCCCCCCCGAAGAGATCGCCCGTGCCGCCGCCCGCC
GGGCGGTCATGATGCTCGGCGCGCGCAAGGCGCCGGGAGGGCTGATGCCGGTGGTCCTCTCGTCGGAGGCCGGCGGCACC
ATGGTGCACGAGGCAATCGGCCACGGCCTTGAGGCGGACCTGGCCGGCAACGGCCTGTCGGTCTACACGGGAAAAGTGGG
GCAACAGGTGGCATCGCCCCTGGTGACGGTGATCGACGACGCCACCATCCCCAACGCGCGGGGCTCGTTCTCCTTCGACG
ATGAGGGAACCCCGGCCCAGCGCACGGTACTGGTGGAGAACGGCATCCTGAAAGGGTATCTCTACGACCGGCTGTCCGCC
ATGAAGGACGGCTGCGCCTCCACGGGCAACGGCAGGCGCGAGGGGTACCACACCAAGCCCATCGTCCGGATGACCAACAC
CCTCATTGCCCCCGGCGAGTCGGACCCGGAGGAGATCGTGCGGGGGGTCGGCCAGGGACTCTTCGTCCGCAAGATGGGCG
GCGGGCAGGTAAATACGGTAAACGGCGACTTCGTGTTCGAAGTCACCGAAGGATATCTTATTGAAAATGGAGCCATCGGG
GAACCGGTCAGGGGAGCCACCCTTACCGGCAACGGCCCGGACATTCTCAAGAAGATCGTCAAGGTCGGCAGCGATCTCGG
CTTCGGCATCGGGACCTGCGGCAAGGACGGTCAGGGTGTGCCGGTCTCCGATGCCCAACCGACGCTTCTCATCGACGAAA
TAACGGTGGGCGGCGCGGCATGA

Upstream 100 bases:

>100_bases
GATACCCCAGCGATTTAACGGAAACTGTCAACGAACTTTTAACAGCACTCGGCACTGAAATTGCTTTAAAAAAGGTGCAA
GGTGACGGGAAACAAGAGAT

Downstream 100 bases:

>100_bases
TGCAATTGGCAGCGATGGACGGCGCCATGCGATGTTTCAGGAGGGAAGGATGTACCTCCCGCTCCGTCACCGGAGGGGAG
GGGCCACGGATGGCTCGCGT

Product: tldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLDQMNLSAILRQALAGGGEFAEIYFEEGSTTAVFCEDGKIEKVLAGTDRGVGIRVISDLRTAYAYTNEVTGTALMELAT
TVSRAVRGKVFEQTIAMKPRAVGAGFPIEITPDGVALHEKIALVERGNKAARDISETIRQVTIAYRDSRVKCQIANSLGD
FIETNRTGTLYLAHVVAAGADVIQTGYEATGKFMGHEIFRERPPEEIARAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
MVHEAIGHGLEADLAGNGLSVYTGKVGQQVASPLVTVIDDATIPNARGSFSFDDEGTPAQRTVLVENGILKGYLYDRLSA
MKDGCASTGNGRREGYHTKPIVRMTNTLIAPGESDPEEIVRGVGQGLFVRKMGGGQVNTVNGDFVFEVTEGYLIENGAIG
EPVRGATLTGNGPDILKKIVKVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIDEITVGGAA

Sequences:

>Translated_460_residues
MLDQMNLSAILRQALAGGGEFAEIYFEEGSTTAVFCEDGKIEKVLAGTDRGVGIRVISDLRTAYAYTNEVTGTALMELAT
TVSRAVRGKVFEQTIAMKPRAVGAGFPIEITPDGVALHEKIALVERGNKAARDISETIRQVTIAYRDSRVKCQIANSLGD
FIETNRTGTLYLAHVVAAGADVIQTGYEATGKFMGHEIFRERPPEEIARAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
MVHEAIGHGLEADLAGNGLSVYTGKVGQQVASPLVTVIDDATIPNARGSFSFDDEGTPAQRTVLVENGILKGYLYDRLSA
MKDGCASTGNGRREGYHTKPIVRMTNTLIAPGESDPEEIVRGVGQGLFVRKMGGGQVNTVNGDFVFEVTEGYLIENGAIG
EPVRGATLTGNGPDILKKIVKVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIDEITVGGAA
>Mature_460_residues
MLDQMNLSAILRQALAGGGEFAEIYFEEGSTTAVFCEDGKIEKVLAGTDRGVGIRVISDLRTAYAYTNEVTGTALMELAT
TVSRAVRGKVFEQTIAMKPRAVGAGFPIEITPDGVALHEKIALVERGNKAARDISETIRQVTIAYRDSRVKCQIANSLGD
FIETNRTGTLYLAHVVAAGADVIQTGYEATGKFMGHEIFRERPPEEIARAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
MVHEAIGHGLEADLAGNGLSVYTGKVGQQVASPLVTVIDDATIPNARGSFSFDDEGTPAQRTVLVENGILKGYLYDRLSA
MKDGCASTGNGRREGYHTKPIVRMTNTLIAPGESDPEEIVRGVGQGLFVRKMGGGQVNTVNGDFVFEVTEGYLIENGAIG
EPVRGATLTGNGPDILKKIVKVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIDEITVGGAA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=473, Percent_Identity=38.9006342494715, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1790682, Length=426, Percent_Identity=24.8826291079812, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48435; Mature: 48435

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDQMNLSAILRQALAGGGEFAEIYFEEGSTTAVFCEDGKIEKVLAGTDRGVGIRVISDL
CCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCEEEEECCCCCCCEEEHHHHH
RTAYAYTNEVTGTALMELATTVSRAVRGKVFEQTIAMKPRAVGAGFPIEITPDGVALHEK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHH
IALVERGNKAARDISETIRQVTIAYRDSRVKCQIANSLGDFIETNRTGTLYLAHVVAAGA
HHHHHCCCHHHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHCCCCCEEEEHHHHHCCH
DVIQTGYEATGKFMGHEIFRERPPEEIARAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
HHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCH
MVHEAIGHGLEADLAGNGLSVYTGKVGQQVASPLVTVIDDATIPNARGSFSFDDEGTPAQ
HHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RTVLVENGILKGYLYDRLSAMKDGCASTGNGRREGYHTKPIVRMTNTLIAPGESDPEEIV
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHEECCEEECCCCCCHHHHH
RGVGQGLFVRKMGGGQVNTVNGDFVFEVTEGYLIENGAIGEPVRGATLTGNGPDILKKIV
HHCCCCEEEEECCCCEEEEECCCEEEEEECCEEEECCCCCCCCCCCEECCCCHHHHHHHH
KVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIDEITVGGAA
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MLDQMNLSAILRQALAGGGEFAEIYFEEGSTTAVFCEDGKIEKVLAGTDRGVGIRVISDL
CCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCCCEEEEECCCCCCCEEEHHHHH
RTAYAYTNEVTGTALMELATTVSRAVRGKVFEQTIAMKPRAVGAGFPIEITPDGVALHEK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHH
IALVERGNKAARDISETIRQVTIAYRDSRVKCQIANSLGDFIETNRTGTLYLAHVVAAGA
HHHHHCCCHHHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHCCCCCEEEEHHHHHCCH
DVIQTGYEATGKFMGHEIFRERPPEEIARAAARRAVMMLGARKAPGGLMPVVLSSEAGGT
HHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCH
MVHEAIGHGLEADLAGNGLSVYTGKVGQQVASPLVTVIDDATIPNARGSFSFDDEGTPAQ
HHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RTVLVENGILKGYLYDRLSAMKDGCASTGNGRREGYHTKPIVRMTNTLIAPGESDPEEIV
EEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHEECCEEECCCCCCHHHHH
RGVGQGLFVRKMGGGQVNTVNGDFVFEVTEGYLIENGAIGEPVRGATLTGNGPDILKKIV
HHCCCCEEEEECCCCEEEEECCCEEEEEECCEEEECCCCCCCCCCCEECCCCHHHHHHHH
KVGSDLGFGIGTCGKDGQGVPVSDAQPTLLIDEITVGGAA
HCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]