Click here to switch to the map view.

The map label for this gene is queC

Identifier: 39995591

GI number: 39995591

Start: 514039

End: 514752

Strand: Direct

Name: queC

Synonym: GSU0483

Alternate gene names: 39995591

Gene position: 514039-514752 (Clockwise)

Preceding gene: 39995590

Following gene: 308513281

Centisome position: 13.48

GC content: 62.32

Gene sequence:

>714_bases
ATGACTAGAAAAGCCGTTGTCCTTTACAGTGGCGGCCTCGACTCCACCACCTGTCTCGCCATTGCGCGGGCCGAGGGATT
CGAGCCCCATGCAATGAGTTTCTCCTACGGCCAACGCCACAGCGTAGAGCTGGAACTGGCAAAAAGAAATGCGCGGCCCG
CAGGGGCCGTCGAACACATGGTGGTGGAGTTCGATTTGCGCAAGGTCGGCGGCAGCGCCCTGACTGCCGATATCGCCGTG
CCAAAGGAGGGGGTGGGGGATGATATCCCGGTTACCTATGTGCCGGCGCGCAACACCATTTTTCTCTCCTTCGCCCTGGG
GTGGGCCGAGGTGCTCGGTGCCTTCGACATCTTCATCGGCGTGAACGCCCTGGATTATTCGGGCTACCCCGACTGCCGCC
CCGAGTACATCTCCGCATTCGAAACCATGGCCAATCTGGCGACCCGGGTTGGTGTAGAAGGGACGGGCCGCTTCCGTATC
CATGCCCCCCTCATGCGTCTCACTAAGGCGGAGATCATCCGGAAGGGGCTCGCTCTGGGAGTCGACTACGGGCTCACCCA
CTCCTGCTACGATCCCTCTCCCGCAGGAGTTGCCTGCGGGCTTTGCGATTCCTGTCGCCTGCGGCTCAAGGGGTTTGCTG
AAGTGGGAGTGGCGGACCCGGTTCCGTACGTGACTGGTGGACAGGGCCTGGGGGGCGGGAAGGAAACGCCATGA

Upstream 100 bases:

>100_bases
GTTTCTGTAGTGTCTTCACCCTTGTCCCTCATCCATTCCTGTTGTACGATGACTCTGGGCTTCCATGCCCATGAAACGCC
CTGTCCGGCGAGGTATTCCC

Downstream 100 bases:

>100_bases
AGGGACAGAAAACAGAAGAAAGCCGTACAACGGCCTCCGAGACACGGTCGTCGACGTCCGCGCCAATGCCCGATATGCAG
ACCAGCCGCGACACCCGCAA

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTRKAVVLYSGGLDSTTCLAIARAEGFEPHAMSFSYGQRHSVELELAKRNARPAGAVEHMVVEFDLRKVGGSALTADIAV
PKEGVGDDIPVTYVPARNTIFLSFALGWAEVLGAFDIFIGVNALDYSGYPDCRPEYISAFETMANLATRVGVEGTGRFRI
HAPLMRLTKAEIIRKGLALGVDYGLTHSCYDPSPAGVACGLCDSCRLRLKGFAEVGVADPVPYVTGGQGLGGGKETP

Sequences:

>Translated_237_residues
MTRKAVVLYSGGLDSTTCLAIARAEGFEPHAMSFSYGQRHSVELELAKRNARPAGAVEHMVVEFDLRKVGGSALTADIAV
PKEGVGDDIPVTYVPARNTIFLSFALGWAEVLGAFDIFIGVNALDYSGYPDCRPEYISAFETMANLATRVGVEGTGRFRI
HAPLMRLTKAEIIRKGLALGVDYGLTHSCYDPSPAGVACGLCDSCRLRLKGFAEVGVADPVPYVTGGQGLGGGKETP
>Mature_236_residues
TRKAVVLYSGGLDSTTCLAIARAEGFEPHAMSFSYGQRHSVELELAKRNARPAGAVEHMVVEFDLRKVGGSALTADIAVP
KEGVGDDIPVTYVPARNTIFLSFALGWAEVLGAFDIFIGVNALDYSGYPDCRPEYISAFETMANLATRVGVEGTGRFRIH
APLMRLTKAEIIRKGLALGVDYGLTHSCYDPSPAGVACGLCDSCRLRLKGFAEVGVADPVPYVTGGQGLGGGKETP

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=239, Percent_Identity=38.0753138075314, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_GEOSL (Q74FW9)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951542.1
- ProteinModelPortal:   Q74FW9
- SMR:   Q74FW9
- GeneID:   2686136
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0483
- NMPDR:   fig|243231.1.peg.480
- TIGR:   GSU0483
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK827865
- BioCyc:   GSUL243231:GSU_0483-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25160; Mature: 25029

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKAVVLYSGGLDSTTCLAIARAEGFEPHAMSFSYGQRHSVELELAKRNARPAGAVEHM
CCCEEEEEEECCCCCHHEEEEEECCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCHHHE
VVEFDLRKVGGSALTADIAVPKEGVGDDIPVTYVPARNTIFLSFALGWAEVLGAFDIFIG
EEEEEHHHCCCCEEEEEEECCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHEEE
VNALDYSGYPDCRPEYISAFETMANLATRVGVEGTGRFRIHAPLMRLTKAEIIRKGLALG
CEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCC
VDYGLTHSCYDPSPAGVACGLCDSCRLRLKGFAEVGVADPVPYVTGGQGLGGGKETP
CCCCCCCCCCCCCCCCEEECCCHHHHHHCCCHHHCCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
TRKAVVLYSGGLDSTTCLAIARAEGFEPHAMSFSYGQRHSVELELAKRNARPAGAVEHM
CCEEEEEEECCCCCHHEEEEEECCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCHHHE
VVEFDLRKVGGSALTADIAVPKEGVGDDIPVTYVPARNTIFLSFALGWAEVLGAFDIFIG
EEEEEHHHCCCCEEEEEEECCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHEEE
VNALDYSGYPDCRPEYISAFETMANLATRVGVEGTGRFRIHAPLMRLTKAEIIRKGLALG
CEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCC
VDYGLTHSCYDPSPAGVACGLCDSCRLRLKGFAEVGVADPVPYVTGGQGLGGGKETP
CCCCCCCCCCCCCCCCEEECCCHHHHHHCCCHHHCCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA