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The map label for this gene is folE2

Identifier: 308513281

GI number: 308513281

Start: 514818

End: 515594

Strand: Direct

Name: folE2

Synonym: NA

Alternate gene names: 308513281

Gene position: 514818-515594 (Clockwise)

Preceding gene: 39995591

Following gene: 39995593

Centisome position: 13.5

GC content: 58.43

Gene sequence:

>777_bases
ATGCCCGATATGCAGACCAGCCGCGACACCCGCAAGATCCCCATCAGCAAGGTGGGGGTGAAGGACATCTCCTATCCCAT
CGTGGTGATGGACAAGAACCGGAAGTTCCAGCAGACCGTGGCCCGGGTGAACATGTATGTGGATCTTCCCCATCATTTCA
AGGGAACCCACATGAGCCGCTTCATCGAGATCCTCAACGCCTACCGCGAGGATATCGCCCTGGACAAGATGGAACCGATC
CTCCAGGAGATGAAAAAAAAGCTCGGTGCATCCTCGGCCCACCTGGAGATTGAGTTTCCCTACTTTATCGAGAAGCGGGC
GCCGGTGTCCGGGGCCAGGAGCCTCATGGAGTATACCTGCACCTTCACGGGGACTCTGGCCGAGACCTTCGATTTCGTGC
TCGGGGTCCAGGTGCCGGTAACCTCTCTGTGCCCGTGCAGCAAGGAGCTTTCCCGCTATGGCGCCCACAACCAGCGCAGC
CATATCACGGTACGGGTCCGGTATGCCGGCTTCGTCTGGATCGAGGAGCTGGTGGAACTGATCGAGGGCTGCGGTTCCAG
CCCGGTGTGGTCGCTTCTCAAGCGTGCCGACGAGAAGTTCGTGACCGAGCGGGCTTACGAGAATCCGAAATTCGTGGAGG
ATATCGTCCGTGAAGCGACCCTGGCTCTAGCCGCCCATGAGGCCATAACCTGGTTCTCGGTGGAAGCCGAAAATTTCGAG
TCGATCCACAAGCATTCCGCCTATGCCGCCATTGAGCAGGATAAGCGAAAGGCATGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:
NA

Sequences:

>Translated_258_residues
MPDMQTSRDTRKIPISKVGVKDISYPIVVMDKNRKFQQTVARVNMYVDLPHHFKGTHMSRFIEILNAYREDIALDKMEPI
LQEMKKKLGASSAHLEIEFPYFIEKRAPVSGARSLMEYTCTFTGTLAETFDFVLGVQVPVTSLCPCSKELSRYGAHNQRS
HITVRVRYAGFVWIEELVELIEGCGSSPVWSLLKRADEKFVTERAYENPKFVEDIVREATLALAAHEAITWFSVEAENFE
SIHKHSAYAAIEQDKRKA
>Mature_257_residues
PDMQTSRDTRKIPISKVGVKDISYPIVVMDKNRKFQQTVARVNMYVDLPHHFKGTHMSRFIEILNAYREDIALDKMEPIL
QEMKKKLGASSAHLEIEFPYFIEKRAPVSGARSLMEYTCTFTGTLAETFDFVLGVQVPVTSLCPCSKELSRYGAHNQRSH
ITVRVRYAGFVWIEELVELIEGCGSSPVWSLLKRADEKFVTERAYENPKFVEDIVREATLALAAHEAITWFSVEAENFES
IHKHSAYAAIEQDKRKA

Specific function: Converts GTP to 7,8-dihydroneopterin triphosphate

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCH4_GEOSL (Q74FW8)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951543.3
- ProteinModelPortal:   Q74FW8
- SMR:   Q74FW8
- GeneID:   2686189
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0484
- NMPDR:   fig|243231.1.peg.481
- TIGR:   GSU0484
- HOGENOM:   HBG626871
- OMA:   SLMDYEV
- ProtClustDB:   PRK13674
- BioCyc:   GSUL243231:GSU_0484-MONOMER
- HAMAP:   MF_01527_B
- InterPro:   IPR022838
- InterPro:   IPR003801
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: =3.5.4.16

Molecular weight: Translated: 29522; Mature: 29391

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDMQTSRDTRKIPISKVGVKDISYPIVVMDKNRKFQQTVARVNMYVDLPHHFKGTHMSR
CCCCCCCCCCCCCCCHHCCHHHCCCCEEEEECCCHHHHHHHHHHHEEECCCCCCCHHHHH
FIEILNAYREDIALDKMEPILQEMKKKLGASSAHLEIEFPYFIEKRAPVSGARSLMEYTC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHCCCCCCHHHHHHHHHHHH
TFTGTLAETFDFVLGVQVPVTSLCPCSKELSRYGAHNQRSHITVRVRYAGFVWIEELVEL
HCCHHHHHHHHHHHCCCCCHHHCCCCHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHH
IEGCGSSPVWSLLKRADEKFVTERAYENPKFVEDIVREATLALAAHEAITWFSVEAENFE
HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHH
SIHKHSAYAAIEQDKRKA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDMQTSRDTRKIPISKVGVKDISYPIVVMDKNRKFQQTVARVNMYVDLPHHFKGTHMSR
CCCCCCCCCCCCCCHHCCHHHCCCCEEEEECCCHHHHHHHHHHHEEECCCCCCCHHHHH
FIEILNAYREDIALDKMEPILQEMKKKLGASSAHLEIEFPYFIEKRAPVSGARSLMEYTC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHCCCCCCHHHHHHHHHHHH
TFTGTLAETFDFVLGVQVPVTSLCPCSKELSRYGAHNQRSHITVRVRYAGFVWIEELVEL
HCCHHHHHHHHHHHCCCCCHHHCCCCHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHH
IEGCGSSPVWSLLKRADEKFVTERAYENPKFVEDIVREATLALAAHEAITWFSVEAENFE
HHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHH
SIHKHSAYAAIEQDKRKA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA