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The map label for this gene is nuoG2 [H]

Identifier: 39995453

GI number: 39995453

Start: 372869

End: 375349

Strand: Direct

Name: nuoG2 [H]

Synonym: GSU0344

Alternate gene names: 39995453

Gene position: 372869-375349 (Clockwise)

Preceding gene: 39995452

Following gene: 39995454

Centisome position: 9.78

GC content: 54.57

Gene sequence:

>2481_bases
ATGGTAACTCTTACAATCGATGACAAGCAGGTAACGGTACCGAAAGACGCTACCATATTTGATGCCGCCAAACAGGCAGG
AATCAGAATTCCCATACTCTGCCACGACAAGAAGCTGCACCCCTTCGGCGGGTGCCGCATGTGCCTAGTCGAAGTCGAGC
AGATGAAGGGTCGCCAGATCCCGGCTTGTACAACGCCCGTTACGGAGGGCATGATAGTCCGGACCATGACCGACGAGATC
GTCAAGGCTCGGAAAATGGTCCTTGAACTGCTCCTGCTCAAGCACCCCATAGACTGTCCTGTCTGTGATGCCGCTGGGGA
TTGCGATCTCCAGAATCTGACTTATGAATACGGCGTAGATACAAACCGCTTTACTGACGAGAAGTTCAACTGGAAGATCG
ACTACGTGAACCCGCTTATCGAGCGGGACATGAACCGTTGCGTTCATTGTGGGAAATGCGCGCGGATTTGTGACGAGATC
GTGTCGTTTGGTGCATATTCCTTTATCAATCGCGGTATAGAAGCAAAAATCGGCACCGAATTCGATGGTCCGCTCAACTG
CGAGTTCTGCGGTTCGTGTGTCTCGGTTTGTCCCGTTGGTGCGCTGATTAGCCGTCCGTTTAAGTTCAAAGCGCGCTGGT
GGGCACTGAATAAGGTAAAGACCGTTTGCTCCTACTGCGGGACTGGCTGCCAGTTGACGCTTGGTGTCAAAGACAACAAG
GTCCTTACCACCATCTATGATGAAAATCAGGGATTTCACAACGGCCAGCTCTGCACTCGTGGCCGGTGGGGATATCAGTT
TGTTAACAGTTCCAAGCGCCTGACCACTCCGCTTATCAGAAAGGGCGATACGCTCCAGCCCGCAAGCTGGGATGAGGCGT
TGGGCATGGTTGCCGACCGGCTCAAGACTTCTAAAGATGCCGCAGCCACATTGGTCACCCCTCGTCTTACCAACGAAGAG
CTTTACCTTCTGAAGCGAGTTGTTAAGGATGCTGTCGGGAGCGACAACCTCGACCATTCCGGCGGCTACGCACATGAGGC
TCTCACTGCTGGCGCGAGGGAGAGCCTTGGATTCCCCGGATCGCCGTCGGTCATCGCCGACATTCAGAAGAGCGAGCTTC
TTCTGGTTATCAAGACGGATGCGTACGAAACGCACCCTGTTATTGGCTTTGAAGTCAACCTAGCAGTCAAGCGCCAAGGC
GTAGCGCTCCGTATTCTTTCTGACAAGAAGGGTAAGCTTTCTCGGCTTCCCGGCGCTCAGACGTATGTCCACACCCCCGG
CGCAGAGTTGGTGCTCGTTAACGCACTCGCCAAGACGATAGTTGATGAAGGACTTCATGATGCCTCCAGCGTCGGAGCCA
TCAAGGGGTTTGACGCATGGCTTAAGAGTATTGAGAGCTGTACACCTGACCAAGCAGCTGGTCAGTGTGGTATTGCTGCG
GACACCATCAAGGCAGTGGCGCGTGAGTACGCAGCAGCCGGTAAGGCTCTGATCATGCTTCCTCTCGGGATGGGGTACCC
GGGGCATGGGAAGGCCCTTGCCCAAGCACTCATTAATCTCGCGCTTCTTACCGGTCGCGTGGGTAAGGAAGGCTGCGGTG
TTCTGATCATGGGCGAGAAGAACAATAGCCAAGGCGCAGCAGATCTCGGGATTCATCCGACCGCTAATGGGTTGAACGCA
CAGGCAATCCTGGCTGGGTGCTCAGCCGGCAGCATCAAAACGTTGTATGTGGTAGGAGAGAATCCGGTGGTTTCCTACCC
TAACCGTAAGCAGGTTGAAGCAGCCCTCGACGCGGTTGAGTTTCTTGTTGTTCAGGATCTGTTCCTCACGGAAACAGCAT
CTAAAGCCGACGTTGTACTTCCCGCCTGCTCCTTCGCAGAAAAGGACGGAACGTTTACAAGTCTCGGTGGGGCTGTCCAA
CGCGTCAATAGAGCAATTACCCCTCTTGGCGACTGCCGCAGTGATTTTGACATCCTTAACATGCTCCATGCAAAGCTGAC
CGGTCAGGCAGCCTATACCAGCCAAAAGGAAGCATTCGCTGATCTTGCCGCGGCCACACCCGGCTATGCGGGTCTGACTC
TTGAAGGTCTAGGGGATGCTGGTGCCGTCAGAGTCAACAACTGCACGGCGTCTTTTGTCCCGGTTGCGACCAGCACTGTG
ACAACTGAGGCAGGGAAGTTCGCACTCCTGACGGGGAGTGCCCTGAACCACTCCGGTACACTGTCACTTTATGGTGAAGG
ACCGATGTTGGTCTGTCCGGAAGGGTATCTGGAGCTTAACAAGGACGACGCCGCAAAACTCTCTATAACCGAGGGTGATG
CGGTAACAATGAAGTCGGCTACAGGCGAACTTCGTCTCAAGGCCAAGGTCGGCACTCGCTTGCCGCAAGGGGTCGCGTTC
GCACCGTACCATTTTGCAGAAGCATCAATCAATTCGCTGACGGGCGCCACGGCTATTACGTGGATAACTATCAGTAAGTA
G

Upstream 100 bases:

>100_bases
GAGAAATGCACCAAATGCAAATCCTGCTACGACGCCTGCCGGTTCATGGCCATCGAGTAGCGAGCTGTAAGTCATACATC
CGAGGGAGACAGAGGTCGAG

Downstream 100 bases:

>100_bases
CAGGTAATAGCCACCAGTTTCCTAACAAAAGACAGAAGAGGAAGAGGAACACATGGGATACGAACTGTTCGGACTGCCAA
TGATCTACTACATCTCCATG

Product: NADH dehydrogenase I subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 826; Mature: 826

Protein sequence:

>826_residues
MVTLTIDDKQVTVPKDATIFDAAKQAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQIPACTTPVTEGMIVRTMTDEI
VKARKMVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYGVDTNRFTDEKFNWKIDYVNPLIERDMNRCVHCGKCARICDEI
VSFGAYSFINRGIEAKIGTEFDGPLNCEFCGSCVSVCPVGALISRPFKFKARWWALNKVKTVCSYCGTGCQLTLGVKDNK
VLTTIYDENQGFHNGQLCTRGRWGYQFVNSSKRLTTPLIRKGDTLQPASWDEALGMVADRLKTSKDAAATLVTPRLTNEE
LYLLKRVVKDAVGSDNLDHSGGYAHEALTAGARESLGFPGSPSVIADIQKSELLLVIKTDAYETHPVIGFEVNLAVKRQG
VALRILSDKKGKLSRLPGAQTYVHTPGAELVLVNALAKTIVDEGLHDASSVGAIKGFDAWLKSIESCTPDQAAGQCGIAA
DTIKAVAREYAAAGKALIMLPLGMGYPGHGKALAQALINLALLTGRVGKEGCGVLIMGEKNNSQGAADLGIHPTANGLNA
QAILAGCSAGSIKTLYVVGENPVVSYPNRKQVEAALDAVEFLVVQDLFLTETASKADVVLPACSFAEKDGTFTSLGGAVQ
RVNRAITPLGDCRSDFDILNMLHAKLTGQAAYTSQKEAFADLAAATPGYAGLTLEGLGDAGAVRVNNCTASFVPVATSTV
TTEAGKFALLTGSALNHSGTLSLYGEGPMLVCPEGYLELNKDDAAKLSITEGDAVTMKSATGELRLKAKVGTRLPQGVAF
APYHFAEASINSLTGATAITWITISK

Sequences:

>Translated_826_residues
MVTLTIDDKQVTVPKDATIFDAAKQAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQIPACTTPVTEGMIVRTMTDEI
VKARKMVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYGVDTNRFTDEKFNWKIDYVNPLIERDMNRCVHCGKCARICDEI
VSFGAYSFINRGIEAKIGTEFDGPLNCEFCGSCVSVCPVGALISRPFKFKARWWALNKVKTVCSYCGTGCQLTLGVKDNK
VLTTIYDENQGFHNGQLCTRGRWGYQFVNSSKRLTTPLIRKGDTLQPASWDEALGMVADRLKTSKDAAATLVTPRLTNEE
LYLLKRVVKDAVGSDNLDHSGGYAHEALTAGARESLGFPGSPSVIADIQKSELLLVIKTDAYETHPVIGFEVNLAVKRQG
VALRILSDKKGKLSRLPGAQTYVHTPGAELVLVNALAKTIVDEGLHDASSVGAIKGFDAWLKSIESCTPDQAAGQCGIAA
DTIKAVAREYAAAGKALIMLPLGMGYPGHGKALAQALINLALLTGRVGKEGCGVLIMGEKNNSQGAADLGIHPTANGLNA
QAILAGCSAGSIKTLYVVGENPVVSYPNRKQVEAALDAVEFLVVQDLFLTETASKADVVLPACSFAEKDGTFTSLGGAVQ
RVNRAITPLGDCRSDFDILNMLHAKLTGQAAYTSQKEAFADLAAATPGYAGLTLEGLGDAGAVRVNNCTASFVPVATSTV
TTEAGKFALLTGSALNHSGTLSLYGEGPMLVCPEGYLELNKDDAAKLSITEGDAVTMKSATGELRLKAKVGTRLPQGVAF
APYHFAEASINSLTGATAITWITISK
>Mature_826_residues
MVTLTIDDKQVTVPKDATIFDAAKQAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQIPACTTPVTEGMIVRTMTDEI
VKARKMVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYGVDTNRFTDEKFNWKIDYVNPLIERDMNRCVHCGKCARICDEI
VSFGAYSFINRGIEAKIGTEFDGPLNCEFCGSCVSVCPVGALISRPFKFKARWWALNKVKTVCSYCGTGCQLTLGVKDNK
VLTTIYDENQGFHNGQLCTRGRWGYQFVNSSKRLTTPLIRKGDTLQPASWDEALGMVADRLKTSKDAAATLVTPRLTNEE
LYLLKRVVKDAVGSDNLDHSGGYAHEALTAGARESLGFPGSPSVIADIQKSELLLVIKTDAYETHPVIGFEVNLAVKRQG
VALRILSDKKGKLSRLPGAQTYVHTPGAELVLVNALAKTIVDEGLHDASSVGAIKGFDAWLKSIESCTPDQAAGQCGIAA
DTIKAVAREYAAAGKALIMLPLGMGYPGHGKALAQALINLALLTGRVGKEGCGVLIMGEKNNSQGAADLGIHPTANGLNA
QAILAGCSAGSIKTLYVVGENPVVSYPNRKQVEAALDAVEFLVVQDLFLTETASKADVVLPACSFAEKDGTFTSLGGAVQ
RVNRAITPLGDCRSDFDILNMLHAKLTGQAAYTSQKEAFADLAAATPGYAGLTLEGLGDAGAVRVNNCTASFVPVATSTV
TTEAGKFALLTGSALNHSGTLSLYGEGPMLVCPEGYLELNKDDAAKLSITEGDAVTMKSATGELRLKAKVGTRLPQGVAF
APYHFAEASINSLTGATAITWITISK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=339, Percent_Identity=30.3834808259587, Blast_Score=196, Evalue=6e-50,
Organism=Escherichia coli, GI3868721, Length=668, Percent_Identity=27.9940119760479, Blast_Score=272, Evalue=6e-74,
Organism=Escherichia coli, GI145693161, Length=736, Percent_Identity=26.9021739130435, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI1788534, Length=565, Percent_Identity=21.4159292035398, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1787778, Length=472, Percent_Identity=21.6101694915254, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1787870, Length=357, Percent_Identity=24.0896358543417, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI171474008, Length=373, Percent_Identity=24.1286863270777, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565758, Length=307, Percent_Identity=35.8306188925081, Blast_Score=210, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI32566231, Length=340, Percent_Identity=33.8235294117647, Blast_Score=209, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI193209088, Length=247, Percent_Identity=36.8421052631579, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24640559, Length=298, Percent_Identity=34.8993288590604, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24640557, Length=298, Percent_Identity=34.8993288590604, Blast_Score=207, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 88099; Mature: 88099

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1 ; PS00490 MOLYBDOPTERIN_PROK_2 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLTIDDKQVTVPKDATIFDAAKQAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQI
CEEEEECCCEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHEEEHHHHCCCCC
PACTTPVTEGMIVRTMTDEIVKARKMVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYGVD
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCC
TNRFTDEKFNWKIDYVNPLIERDMNRCVHCGKCARICDEIVSFGAYSFINRGIEAKIGTE
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
FDGPLNCEFCGSCVSVCPVGALISRPFKFKARWWALNKVKTVCSYCGTGCQLTLGVKDNK
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHCCCCCEEEEECCCCE
VLTTIYDENQGFHNGQLCTRGRWGYQFVNSSKRLTTPLIRKGDTLQPASWDEALGMVADR
EEEEEEECCCCCCCCCEEECCCCCHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHH
LKTSKDAAATLVTPRLTNEELYLLKRVVKDAVGSDNLDHSGGYAHEALTAGARESLGFPG
HHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHCCCCC
SPSVIADIQKSELLLVIKTDAYETHPVIGFEVNLAVKRQGVALRILSDKKGKLSRLPGAQ
CCHHEEECCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCEEEEEECCCCCCHHCCCCCC
TYVHTPGAELVLVNALAKTIVDEGLHDASSVGAIKGFDAWLKSIESCTPDQAAGQCGIAA
EEEECCCCCEEHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCHHCCCCCCHH
DTIKAVAREYAAAGKALIMLPLGMGYPGHGKALAQALINLALLTGRVGKEGCGVLIMGEK
HHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
NNSQGAADLGIHPTANGLNAQAILAGCSAGSIKTLYVVGENPVVSYPNRKQVEAALDAVE
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEECCCCHHHHHHHHHHHH
FLVVQDLFLTETASKADVVLPACSFAEKDGTFTSLGGAVQRVNRAITPLGDCRSDFDILN
HHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MLHAKLTGQAAYTSQKEAFADLAAATPGYAGLTLEGLGDAGAVRVNNCTASFVPVATSTV
HHHHHHCCCHHHCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECCCCEEEEEEEEEEE
TTEAGKFALLTGSALNHSGTLSLYGEGPMLVCPEGYLELNKDDAAKLSITEGDAVTMKSA
EECCCCEEEEECCCCCCCCEEEEECCCCEEECCCCCEEECCCCCEEEEEECCCEEEEECC
TGELRLKAKVGTRLPQGVAFAPYHFAEASINSLTGATAITWITISK
CCCEEEEEECCCCCCCCCEECCCHHHHHHHHHCCCCEEEEEEEEEC
>Mature Secondary Structure
MVTLTIDDKQVTVPKDATIFDAAKQAGIRIPILCHDKKLHPFGGCRMCLVEVEQMKGRQI
CEEEEECCCEEECCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHEEEHHHHCCCCC
PACTTPVTEGMIVRTMTDEIVKARKMVLELLLLKHPIDCPVCDAAGDCDLQNLTYEYGVD
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCC
TNRFTDEKFNWKIDYVNPLIERDMNRCVHCGKCARICDEIVSFGAYSFINRGIEAKIGTE
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
FDGPLNCEFCGSCVSVCPVGALISRPFKFKARWWALNKVKTVCSYCGTGCQLTLGVKDNK
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHCCCCCEEEEECCCCE
VLTTIYDENQGFHNGQLCTRGRWGYQFVNSSKRLTTPLIRKGDTLQPASWDEALGMVADR
EEEEEEECCCCCCCCCEEECCCCCHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHH
LKTSKDAAATLVTPRLTNEELYLLKRVVKDAVGSDNLDHSGGYAHEALTAGARESLGFPG
HHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHCCCCC
SPSVIADIQKSELLLVIKTDAYETHPVIGFEVNLAVKRQGVALRILSDKKGKLSRLPGAQ
CCHHEEECCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCEEEEEECCCCCCHHCCCCCC
TYVHTPGAELVLVNALAKTIVDEGLHDASSVGAIKGFDAWLKSIESCTPDQAAGQCGIAA
EEEECCCCCEEHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCHHCCCCCCHH
DTIKAVAREYAAAGKALIMLPLGMGYPGHGKALAQALINLALLTGRVGKEGCGVLIMGEK
HHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
NNSQGAADLGIHPTANGLNAQAILAGCSAGSIKTLYVVGENPVVSYPNRKQVEAALDAVE
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEECCCCHHHHHHHHHHHH
FLVVQDLFLTETASKADVVLPACSFAEKDGTFTSLGGAVQRVNRAITPLGDCRSDFDILN
HHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MLHAKLTGQAAYTSQKEAFADLAAATPGYAGLTLEGLGDAGAVRVNNCTASFVPVATSTV
HHHHHHCCCHHHCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECCCCEEEEEEEEEEE
TTEAGKFALLTGSALNHSGTLSLYGEGPMLVCPEGYLELNKDDAAKLSITEGDAVTMKSA
EECCCCEEEEECCCCCCCCEEEEECCCCEEECCCCCEEECCCCCEEEEEECCCEEEEECC
TGELRLKAKVGTRLPQGVAFAPYHFAEASINSLTGATAITWITISK
CCCEEEEEECCCCCCCCCEECCCHHHHHHHHHCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]