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The map label for this gene is nuoA-1

Identifier: 39995447

GI number: 39995447

Start: 367863

End: 368219

Strand: Direct

Name: nuoA-1

Synonym: GSU0338

Alternate gene names: 39995447

Gene position: 367863-368219 (Clockwise)

Preceding gene: 39995441

Following gene: 39995448

Centisome position: 9.64

GC content: 48.18

Gene sequence:

>357_bases
ATGCTGGGTGTATACCTGCCAATCATTGTCCTGGTAGCGGTAGCGGTCATATTTGGTCTGGCTTCATTAACCTTCTCGTC
GCTGATAGGGCAGAAGAAGCCGAGTGCGGTGAAGCTTGCCCCTTACGAGTGTGGCTGTGAACCGGTCGGCTCTGCCCGGG
AACGCTTCTCGGTAAAGTTCTACATTATTGCCATGCTGTTTATTCTCTTTGATATTGAAGCTGTATTTATGTATCCCTGG
TCGGTTCTGTTTAAGCGGCTTGGGATATTTGGCGTTGTCGAGATGGGTCTGTTCATCGTCATTCTTTTTGTCGGTTACAT
CTATGTCTGGAAAAAAGGAGCTCTGGAATGGGAGTAG

Upstream 100 bases:

>100_bases
GTATACAGTATACGCAAGCTGGTAAAGCGGCTTCATAACTGCAACTAGAGTTCGAAACGCGGTAGAAAGACAACCCCAAA
GAAGAGTGGAGGGATTGGAA

Downstream 100 bases:

>100_bases
ATCAGCCGCTGGGAGATAACTTCATCACCACGTCCCTGGACAGTCTCGTGAACTGGGCGAGGAAGTCCTCCATCTGGCCC
ATGACCTTTGGTCTTGCTTG

Product: NADH dehydrogenase I subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 1; NDH-1 subunit A 1; NUO1 1

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MLGVYLPIIVLVAVAVIFGLASLTFSSLIGQKKPSAVKLAPYECGCEPVGSARERFSVKFYIIAMLFILFDIEAVFMYPW
SVLFKRLGIFGVVEMGLFIVILFVGYIYVWKKGALEWE

Sequences:

>Translated_118_residues
MLGVYLPIIVLVAVAVIFGLASLTFSSLIGQKKPSAVKLAPYECGCEPVGSARERFSVKFYIIAMLFILFDIEAVFMYPW
SVLFKRLGIFGVVEMGLFIVILFVGYIYVWKKGALEWE
>Mature_118_residues
MLGVYLPIIVLVAVAVIFGLASLTFSSLIGQKKPSAVKLAPYECGCEPVGSARERFSVKFYIIAMLFILFDIEAVFMYPW
SVLFKRLGIFGVVEMGLFIVILFVGYIYVWKKGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=89, Percent_Identity=41.5730337078652, Blast_Score=84, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA1_GEOSL (Q74GA8)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_951398.1
- GeneID:   2686820
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU0338
- NMPDR:   fig|243231.1.peg.336
- TIGR:   GSU0338
- HOGENOM:   HBG605540
- OMA:   IGFAYEW
- ProtClustDB:   CLSK827761
- BioCyc:   GSUL243231:GSU_0338-MONOMER
- GO:   GO:0006810
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13254; Mature: 13254

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc8044d8)-; HASH(0xbfeefa4)-; HASH(0xb3bed98)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGVYLPIIVLVAVAVIFGLASLTFSSLIGQKKPSAVKLAPYECGCEPVGSARERFSVKF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHCCCCCCCCHHHHHHHHH
YIIAMLFILFDIEAVFMYPWSVLFKRLGIFGVVEMGLFIVILFVGYIYVWKKGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MLGVYLPIIVLVAVAVIFGLASLTFSSLIGQKKPSAVKLAPYECGCEPVGSARERFSVKF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHCCCCCCCCHHHHHHHHH
YIIAMLFILFDIEAVFMYPWSVLFKRLGIFGVVEMGLFIVILFVGYIYVWKKGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA