Click here to switch to the map view.

The map label for this gene is yycG [H]

Identifier: 39995255

GI number: 39995255

Start: 158787

End: 160916

Strand: Direct

Name: yycG [H]

Synonym: GSU0144

Alternate gene names: 39995255

Gene position: 158787-160916 (Clockwise)

Preceding gene: 39995254

Following gene: 39995256

Centisome position: 4.16

GC content: 62.02

Gene sequence:

>2130_bases
ATGTCCTTACGCAACGACAGGGTGTATCTGATTGTTGTCAGTGTTTCGGCGCTCCTGGTGCTTGGCGTGCTTGCGGCGTC
CTTTGTCGTCTACCGTCGCCACGATTTTCCCCTCCTCGACTTCCTTACCCTGGTTCTTTTCCTGCTCGTTTCCTGCATCA
TTTTCATGGTGGTCAGCTACCGCAAGACACGCAGCGTCAATGAACTGGCCCATTTGCACGAGCTTATGCAGTACCAGCGG
GAGCTGGACAAGATCGCCCGGCGCTACCGGAGTCTTCTGGAAGGGGCCGGCAATGCGGTCTTCGTCTTCAATGCCGACAC
GGGGCTTCTGGTGGAGGTGAACCGTCGGGGCACCGAACTGCTGGGGTACAGCAAGGAGGAAATGGTCACTCTCAAGGGGA
AGGACCTGGTGCCCGAGGAGGACCAGGAGAAGTTTTCCCTGCTGGTATTGAGGGTGGTCCGGCGCGGAAGGGGCCGGACC
GACGGAATTGCGTTCCGCCGCCGGGGAGGGGATCGCTTCCTGGGGGAGGTGGAAGCCCGCCTCATTGATCTGGGCGACGA
GAAGGTGGTCCATGCCACGATCAGGGACATCACATTCAAGCACCGGGCCGAGCGGGAGATGCGCCAGCGCAACCGGGAGC
TCGCCTCCCTGGTGAACATCATCACCAGAGCCAACCAGGAGATGGAGCTGGAGACGGTCCTCGACGTAACCCTGCGGGAA
ACGATCGAAGTCTTCGGCGTTGACGGCGGCGGCATCCATCTGCGCGAGCGGGACGGCACCCTGCGCCCGGCAGCTACCTG
TTTCGTTCCGGATCGGCTCAGGGAGGCGCTTGATGCCGGAGCCGACGGCGGACTGTTGGGCAGGGTTGCCGCCACGCGCG
GCCCTTTCGCCCTGGACGATCTGGCCATGGAAGGGTGCATGGCGGGGCTCTCGGATGAGTCGGCAGGCTGGAAGGGGTTT
GCGGCGGTCCCGCTGTTCGCCAAGAACCGGGTCACCGGCGTCATGTACCTGTTGAACCGGCAGATGCGTTCCTTCACCGA
CGAAGAGCTCAAGCTGTTCTTTTCCATAGCCGGCCAGATGGGCATCATCATCGAAAACGCCCGCCTCTTCAATGAACTCA
AGTGGAAAAGCGATGAGCTCATGGGGTCGTTCCGCCTCCTGGAGAAAAGCAGTCACGAGCTTGCCCTTTCCCAGCACCGG
CTCCGCACCAATCTGACCCTCGTGGAACGCGCCAATCAGGAGCTGGAGCGAATCGACCGGATGAAGAACAACTTTCTCGG
CATGATTTCCCATGAGTTTCGCACCCCCCTTACCAGCGTCATCAGCGGCACCGATTTTCTGCGCTCCTCGTCAAGCCTAG
CCGGCGACCCCGACAGCCGGCAGGTCCTCGACATGATCCACGAGGGGGGAGAGCGCCTTTTCGAGATCGTCAACGATATC
CTCAAGGTTGCCCGTCTTGAGGCCAAGTCGGCCACTGTGGCCCGGCGTGCCCTCCACATCTCCCAGGTGTTCAGCCAGGT
GGTGACGAAGCTTGAGCCGCTGCTTGCGGAGCGGAGCCTGCGAATCGTCTTCAACAACCTGGAGGGGCTCCCCCACTGCA
TAGGCGACCAGGAGTGCTTCGAGGAGATATTCTCGGAACTGCTGGAAAACTCGGTCAAGTTCACTCCGGACGGGGGGACG
ATCATCATCTCGGCGCGGGTGGTCGACCGGCGGGCCCTTGCCCCGAAGCGGGAGATCCTGGCGCGCTTCAATGCCGATTT
CCCGAGCCAGATCGGGGATCGCTGCTATCTGGAGGTGGCGGTCCGCGACAACGGCATCGGGGTCAGCCACGACGAGCAGG
TGAAGATATTCGACAAATTCTACGAAATTGGCGATATCCGTCACCACTCCAGCGGCAAGTTCAAGTTCCAGGGAAAGGGG
ACGGGGCTTGGACTGGCCATCGTCAAGGGGATGGTGGAGGCCCATGGGGGCATGGTCTGGGTCGAGAGCCCGGGGGTTGA
TCCGGAGGCCCGCTTCGGCAGCGCGTTTCTGGTTCTCCTTCCCCTTGAGGAGAGTCTGCGGACGCCGGTCATCCCTCTGG
CCGCCCCCCGGGATCCCCTGGCGGGAGACATCCCCGGAGAGGGAGCGTGA

Upstream 100 bases:

>100_bases
ACCGTCACGGCCGTCACGGCCCTGGACTGGCTGAGGAGGCGCCTCCTCACCGCCTGAATCGAAGCCGCTGTCCTTTTCTC
CCGCAGCGGGAAAGCTCGTC

Downstream 100 bases:

>100_bases
CACCCTTTCGAAACGGGCAGGATCTGCCGGAAAGATACCCTTGAAAAGACCGAAAGATCTGTGTTATTTCTGATCAACTG
ACCGATACGAAACGTGGCGC

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MSLRNDRVYLIVVSVSALLVLGVLAASFVVYRRHDFPLLDFLTLVLFLLVSCIIFMVVSYRKTRSVNELAHLHELMQYQR
ELDKIARRYRSLLEGAGNAVFVFNADTGLLVEVNRRGTELLGYSKEEMVTLKGKDLVPEEDQEKFSLLVLRVVRRGRGRT
DGIAFRRRGGDRFLGEVEARLIDLGDEKVVHATIRDITFKHRAEREMRQRNRELASLVNIITRANQEMELETVLDVTLRE
TIEVFGVDGGGIHLRERDGTLRPAATCFVPDRLREALDAGADGGLLGRVAATRGPFALDDLAMEGCMAGLSDESAGWKGF
AAVPLFAKNRVTGVMYLLNRQMRSFTDEELKLFFSIAGQMGIIIENARLFNELKWKSDELMGSFRLLEKSSHELALSQHR
LRTNLTLVERANQELERIDRMKNNFLGMISHEFRTPLTSVISGTDFLRSSSSLAGDPDSRQVLDMIHEGGERLFEIVNDI
LKVARLEAKSATVARRALHISQVFSQVVTKLEPLLAERSLRIVFNNLEGLPHCIGDQECFEEIFSELLENSVKFTPDGGT
IIISARVVDRRALAPKREILARFNADFPSQIGDRCYLEVAVRDNGIGVSHDEQVKIFDKFYEIGDIRHHSSGKFKFQGKG
TGLGLAIVKGMVEAHGGMVWVESPGVDPEARFGSAFLVLLPLEESLRTPVIPLAAPRDPLAGDIPGEGA

Sequences:

>Translated_709_residues
MSLRNDRVYLIVVSVSALLVLGVLAASFVVYRRHDFPLLDFLTLVLFLLVSCIIFMVVSYRKTRSVNELAHLHELMQYQR
ELDKIARRYRSLLEGAGNAVFVFNADTGLLVEVNRRGTELLGYSKEEMVTLKGKDLVPEEDQEKFSLLVLRVVRRGRGRT
DGIAFRRRGGDRFLGEVEARLIDLGDEKVVHATIRDITFKHRAEREMRQRNRELASLVNIITRANQEMELETVLDVTLRE
TIEVFGVDGGGIHLRERDGTLRPAATCFVPDRLREALDAGADGGLLGRVAATRGPFALDDLAMEGCMAGLSDESAGWKGF
AAVPLFAKNRVTGVMYLLNRQMRSFTDEELKLFFSIAGQMGIIIENARLFNELKWKSDELMGSFRLLEKSSHELALSQHR
LRTNLTLVERANQELERIDRMKNNFLGMISHEFRTPLTSVISGTDFLRSSSSLAGDPDSRQVLDMIHEGGERLFEIVNDI
LKVARLEAKSATVARRALHISQVFSQVVTKLEPLLAERSLRIVFNNLEGLPHCIGDQECFEEIFSELLENSVKFTPDGGT
IIISARVVDRRALAPKREILARFNADFPSQIGDRCYLEVAVRDNGIGVSHDEQVKIFDKFYEIGDIRHHSSGKFKFQGKG
TGLGLAIVKGMVEAHGGMVWVESPGVDPEARFGSAFLVLLPLEESLRTPVIPLAAPRDPLAGDIPGEGA
>Mature_708_residues
SLRNDRVYLIVVSVSALLVLGVLAASFVVYRRHDFPLLDFLTLVLFLLVSCIIFMVVSYRKTRSVNELAHLHELMQYQRE
LDKIARRYRSLLEGAGNAVFVFNADTGLLVEVNRRGTELLGYSKEEMVTLKGKDLVPEEDQEKFSLLVLRVVRRGRGRTD
GIAFRRRGGDRFLGEVEARLIDLGDEKVVHATIRDITFKHRAEREMRQRNRELASLVNIITRANQEMELETVLDVTLRET
IEVFGVDGGGIHLRERDGTLRPAATCFVPDRLREALDAGADGGLLGRVAATRGPFALDDLAMEGCMAGLSDESAGWKGFA
AVPLFAKNRVTGVMYLLNRQMRSFTDEELKLFFSIAGQMGIIIENARLFNELKWKSDELMGSFRLLEKSSHELALSQHRL
RTNLTLVERANQELERIDRMKNNFLGMISHEFRTPLTSVISGTDFLRSSSSLAGDPDSRQVLDMIHEGGERLFEIVNDIL
KVARLEAKSATVARRALHISQVFSQVVTKLEPLLAERSLRIVFNNLEGLPHCIGDQECFEEIFSELLENSVKFTPDGGTI
IISARVVDRRALAPKREILARFNADFPSQIGDRCYLEVAVRDNGIGVSHDEQVKIFDKFYEIGDIRHHSSGKFKFQGKGT
GLGLAIVKGMVEAHGGMVWVESPGVDPEARFGSAFLVLLPLEESLRTPVIPLAAPRDPLAGDIPGEGA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=284, Percent_Identity=28.8732394366197, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1789149, Length=297, Percent_Identity=27.6094276094276, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1786783, Length=283, Percent_Identity=27.208480565371, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI48994928, Length=278, Percent_Identity=29.136690647482, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786912, Length=324, Percent_Identity=25.9259259259259, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=276, Percent_Identity=27.536231884058, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788393, Length=326, Percent_Identity=26.9938650306748, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=274, Percent_Identity=22.992700729927, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=24.7104247104247, Blast_Score=76, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79314; Mature: 79182

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRNDRVYLIVVSVSALLVLGVLAASFVVYRRHDFPLLDFLTLVLFLLVSCIIFMVVSY
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RKTRSVNELAHLHELMQYQRELDKIARRYRSLLEGAGNAVFVFNADTGLLVEVNRRGTEL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCHH
LGYSKEEMVTLKGKDLVPEEDQEKFSLLVLRVVRRGRGRTDGIAFRRRGGDRFLGEVEAR
HCCCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHEECCCCHHHHHHHHH
LIDLGDEKVVHATIRDITFKHRAEREMRQRNRELASLVNIITRANQEMELETVLDVTLRE
HHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TIEVFGVDGGGIHLRERDGTLRPAATCFVPDRLREALDAGADGGLLGRVAATRGPFALDD
HHHHEECCCCCEEEECCCCCCCCHHEECCHHHHHHHHHCCCCCCEEEHHHHCCCCCHHHH
LAMEGCMAGLSDESAGWKGFAAVPLFAKNRVTGVMYLLNRQMRSFTDEELKLFFSIAGQM
HHHHHHHCCCCCCCCCCCCEEECCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GIIIENARLFNELKWKSDELMGSFRLLEKSSHELALSQHRLRTNLTLVERANQELERIDR
CEEEECHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKNNFLGMISHEFRTPLTSVISGTDFLRSSSSLAGDPDSRQVLDMIHEGGERLFEIVNDI
HHHHHHHHHHHHHHCHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHH
LKVARLEAKSATVARRALHISQVFSQVVTKLEPLLAERSLRIVFNNLEGLPHCIGDQECF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHH
EEIFSELLENSVKFTPDGGTIIISARVVDRRALAPKREILARFNADFPSQIGDRCYLEVA
HHHHHHHHHCCCEECCCCCEEEEEEEEHHHHHCCCHHHHHHHHCCCCCHHCCCCEEEEEE
VRDNGIGVSHDEQVKIFDKFYEIGDIRHHSSGKFKFQGKGTGLGLAIVKGMVEAHGGMVW
EECCCCCCCCCCHHHHHHHHHHHCCCEECCCCCEEEECCCCCHHHHHHHHHHHHCCCEEE
VESPGVDPEARFGSAFLVLLPLEESLRTPVIPLAAPRDPLAGDIPGEGA
EECCCCCCCCCCCCEEEEEEECHHHHCCCCEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLRNDRVYLIVVSVSALLVLGVLAASFVVYRRHDFPLLDFLTLVLFLLVSCIIFMVVSY
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RKTRSVNELAHLHELMQYQRELDKIARRYRSLLEGAGNAVFVFNADTGLLVEVNRRGTEL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCHH
LGYSKEEMVTLKGKDLVPEEDQEKFSLLVLRVVRRGRGRTDGIAFRRRGGDRFLGEVEAR
HCCCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHEECCCCHHHHHHHHH
LIDLGDEKVVHATIRDITFKHRAEREMRQRNRELASLVNIITRANQEMELETVLDVTLRE
HHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TIEVFGVDGGGIHLRERDGTLRPAATCFVPDRLREALDAGADGGLLGRVAATRGPFALDD
HHHHEECCCCCEEEECCCCCCCCHHEECCHHHHHHHHHCCCCCCEEEHHHHCCCCCHHHH
LAMEGCMAGLSDESAGWKGFAAVPLFAKNRVTGVMYLLNRQMRSFTDEELKLFFSIAGQM
HHHHHHHCCCCCCCCCCCCEEECCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
GIIIENARLFNELKWKSDELMGSFRLLEKSSHELALSQHRLRTNLTLVERANQELERIDR
CEEEECHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKNNFLGMISHEFRTPLTSVISGTDFLRSSSSLAGDPDSRQVLDMIHEGGERLFEIVNDI
HHHHHHHHHHHHHHCHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHH
LKVARLEAKSATVARRALHISQVFSQVVTKLEPLLAERSLRIVFNNLEGLPHCIGDQECF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHH
EEIFSELLENSVKFTPDGGTIIISARVVDRRALAPKREILARFNADFPSQIGDRCYLEVA
HHHHHHHHHCCCEECCCCCEEEEEEEEHHHHHCCCHHHHHHHHCCCCCHHCCCCEEEEEE
VRDNGIGVSHDEQVKIFDKFYEIGDIRHHSSGKFKFQGKGTGLGLAIVKGMVEAHGGMVW
EECCCCCCCCCCHHHHHHHHHHHCCCEECCCCCEEEECCCCCHHHHHHHHHHHHCCCEEE
VESPGVDPEARFGSAFLVLLPLEESLRTPVIPLAAPRDPLAGDIPGEGA
EECCCCCCCCCCCCEEEEEEECHHHHCCCCEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]