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The map label for this gene is hypB1

Identifier: 38637681

GI number: 38637681

Start: 8947

End: 10032

Strand: Direct

Name: hypB1

Synonym: PHG013

Alternate gene names: 38637681

Gene position: 8947-10032 (Clockwise)

Preceding gene: 38637680

Following gene: 38637682

Centisome position: 1.98

GC content: 62.98

Gene sequence:

>1086_bases
ATGTGCGTCATATGTGGATGCAATACCAATCACGAGACTGCCCGGCAAGACGAGAATAAGGGCGAACATGCTCCCGGCCG
TGGCCTCGTCGATACCGGCACCGAGCCGCCGGGCGCGGCGCATGTACGGATCGATGCGTCCACCGGTGATCTGCACTACG
GCGCGGGGCCGGCGCACGTGTCTGTGCCGGGTCTCAGTCAAGCGCGTGCGATCAAACTGGAACAGGACGTGCTGGGTCAC
AACAATCGCCTTGCTGCACACAACCGTCAGCATTTCGTCGCACATGGTGTGCTTGCACTGAATCTCGTTTCCAGTCCGGG
GTCGGGCAAGACGACCTTGCTCTGCACTACCATCGAAGCCTTGCGGCGGTGCCGTGCGGACCTGCAGCTGGCCGTGATCG
AGGGCGACCAGCAGACCAGTCATGACGCAGAGCGCATCCGGGCCACGGGTGTACCTGCGATCCAGATCAATACCGGCAAG
GGCTGTCATCTCGATGCGCTAATGGTTGCCAATGCGTACGAGCGCCTCCCCTTGCACGCCGCGGCACATGCGCACACCCA
TGAGCACCGTCAAGAGGACGGACAGCATTCCCACCATCATGACCACGAGCATGCTCGCCACGATCACCACGATCACCGAT
CCAGCGGCATCGGCAGCGTCTTGTTCATAGAAAACGTCGGCAATCTGGTGTGCCCTGCAATGTGGGATCTGGGCGAATCC
GCGAAGGTGGCGATCCTGTCGGTGACCGAGGGCGAGGACAAGCCGCTCAAGTATCCCGACATGTTCGCCGCCGCCAGCCT
GATGATCCTGAACAAGATCGACCTGCTGCCACATCTGCGCTTCGATGTAGCACGCTGCATCGAATATGCGCGGCAAGTCA
ATCCGCACCTTCAGGTGCTGCAGCTGTCGGCCGCGACAGGAGAGGGCGTGGACGAGTGGCTAGACTGGATGCTGGCCGGC
GGCGCGGCGGCAGGGGCTGCTGCCGCAACGGATGGCGCGCGCATGCGTATCGCCGCGCCGGAGGCCGGAATCGCTGCCCT
CGGAACGCAGTTGGCTCCCGGTCCGGCGGTGTCGAAGGAGATGTGA

Upstream 100 bases:

>100_bases
TGGACATGCTGGTCGAAGATCACTGGTGTCCTGAATGAAAAATTCATTGAATCAGGACACCAGGGTGAAGCGATCTGCGA
GAAGAAAGGAGTAGGCGAAA

Downstream 100 bases:

>100_bases
GATGCGAGCGCAGACCTTGCCAGCCGGCAGCGACCATGCGCCGGTGCTGGCTTGCGGTGCATGGCTGAAGAATGCCGCAT
GCCTGTTGCGGGGCGCCGAG

Product: HypB1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MCVICGCNTNHETARQDENKGEHAPGRGLVDTGTEPPGAAHVRIDASTGDLHYGAGPAHVSVPGLSQARAIKLEQDVLGH
NNRLAAHNRQHFVAHGVLALNLVSSPGSGKTTLLCTTIEALRRCRADLQLAVIEGDQQTSHDAERIRATGVPAIQINTGK
GCHLDALMVANAYERLPLHAAAHAHTHEHRQEDGQHSHHHDHEHARHDHHDHRSSGIGSVLFIENVGNLVCPAMWDLGES
AKVAILSVTEGEDKPLKYPDMFAAASLMILNKIDLLPHLRFDVARCIEYARQVNPHLQVLQLSAATGEGVDEWLDWMLAG
GAAAGAAAATDGARMRIAAPEAGIAALGTQLAPGPAVSKEM

Sequences:

>Translated_361_residues
MCVICGCNTNHETARQDENKGEHAPGRGLVDTGTEPPGAAHVRIDASTGDLHYGAGPAHVSVPGLSQARAIKLEQDVLGH
NNRLAAHNRQHFVAHGVLALNLVSSPGSGKTTLLCTTIEALRRCRADLQLAVIEGDQQTSHDAERIRATGVPAIQINTGK
GCHLDALMVANAYERLPLHAAAHAHTHEHRQEDGQHSHHHDHEHARHDHHDHRSSGIGSVLFIENVGNLVCPAMWDLGES
AKVAILSVTEGEDKPLKYPDMFAAASLMILNKIDLLPHLRFDVARCIEYARQVNPHLQVLQLSAATGEGVDEWLDWMLAG
GAAAGAAAATDGARMRIAAPEAGIAALGTQLAPGPAVSKEM
>Mature_361_residues
MCVICGCNTNHETARQDENKGEHAPGRGLVDTGTEPPGAAHVRIDASTGDLHYGAGPAHVSVPGLSQARAIKLEQDVLGH
NNRLAAHNRQHFVAHGVLALNLVSSPGSGKTTLLCTTIEALRRCRADLQLAVIEGDQQTSHDAERIRATGVPAIQINTGK
GCHLDALMVANAYERLPLHAAAHAHTHEHRQEDGQHSHHHDHEHARHDHHDHRSSGIGSVLFIENVGNLVCPAMWDLGES
AKVAILSVTEGEDKPLKYPDMFAAASLMILNKIDLLPHLRFDVARCIEYARQVNPHLQVLQLSAATGEGVDEWLDWMLAG
GAAAGAAAATDGARMRIAAPEAGIAALGTQLAPGPAVSKEM

Specific function: Could be involved in nickel binding and accumulation

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family

Homologues:

Organism=Escherichia coli, GI1789082, Length=328, Percent_Identity=50, Blast_Score=300, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPB_CUPNH (P31902)

Other databases:

- EMBL:   X70183
- EMBL:   AY305378
- PIR:   I39529
- RefSeq:   NP_942655.1
- ProteinModelPortal:   P31902
- SMR:   P31902
- GeneID:   2656434
- GenomeReviews:   AY305378_GR
- KEGG:   reh:PHG013
- HOGENOM:   HBG364734
- OMA:   GCHLDAP
- PhylomeDB:   P31902
- ProtClustDB:   CLSK923799
- BioCyc:   REUT381666:PHG013-MONOMER
- InterPro:   IPR003495
- InterPro:   IPR004392
- TIGRFAMs:   TIGR00073

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 38484; Mature: 38484

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVICGCNTNHETARQDENKGEHAPGRGLVDTGTEPPGAAHVRIDASTGDLHYGAGPAHV
CEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCEE
SVPGLSQARAIKLEQDVLGHNNRLAAHNRQHFVAHGVLALNLVSSPGSGKTTLLCTTIEA
ECCCCCCHHEEEEHHHHHCCCCEEECCCCCHHHHHCEEEEEEECCCCCCCEEEEEHHHHH
LRRCRADLQLAVIEGDQQTSHDAERIRATGVPAIQINTGKGCHLDALMVANAYERLPLHA
HHHHHCCEEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHH
AAHAHTHEHRQEDGQHSHHHDHEHARHDHHDHRSSGIGSVLFIENVGNLVCPAMWDLGES
HHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHCCCCEEEEEECCCCEECHHHHCCCCC
AKVAILSVTEGEDKPLKYPDMFAAASLMILNKIDLLPHLRFDVARCIEYARQVNPHLQVL
CEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
QLSAATGEGVDEWLDWMLAGGAAAGAAAATDGARMRIAAPEAGIAALGTQLAPGPAVSKE
EEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCCC
M
C
>Mature Secondary Structure
MCVICGCNTNHETARQDENKGEHAPGRGLVDTGTEPPGAAHVRIDASTGDLHYGAGPAHV
CEEEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCEE
SVPGLSQARAIKLEQDVLGHNNRLAAHNRQHFVAHGVLALNLVSSPGSGKTTLLCTTIEA
ECCCCCCHHEEEEHHHHHCCCCEEECCCCCHHHHHCEEEEEEECCCCCCCEEEEEHHHHH
LRRCRADLQLAVIEGDQQTSHDAERIRATGVPAIQINTGKGCHLDALMVANAYERLPLHA
HHHHHCCEEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHH
AAHAHTHEHRQEDGQHSHHHDHEHARHDHHDHRSSGIGSVLFIENVGNLVCPAMWDLGES
HHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHCCCCEEEEEECCCCEECHHHHCCCCC
AKVAILSVTEGEDKPLKYPDMFAAASLMILNKIDLLPHLRFDVARCIEYARQVNPHLQVL
CEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
QLSAATGEGVDEWLDWMLAGGAAAGAAAATDGARMRIAAPEAGIAALGTQLAPGPAVSKE
EEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCCCC
M
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8352644; 12948488