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The map label for this gene is nadB [H]

Identifier: 38234794

GI number: 38234794

Start: 2350425

End: 2351654

Strand: Direct

Name: nadB [H]

Synonym: DIP2258

Alternate gene names: 38234794

Gene position: 2350425-2351654 (Clockwise)

Preceding gene: 38234793

Following gene: 38234795

Centisome position: 94.45

GC content: 49.59

Gene sequence:

>1230_bases
ATGATCTTCGAAGTTGATCTTGGCTCTACCGATTATATTGAAGAGCATGATGCCGTTATAGTAGGCGGCGGGGCAGCAGG
GCTTCGCTCTGCGATTAGTTTAGCTGAGAGAGGCATAAGCCCAATCATATTGACAAAAACTACTGTAGATGAATGCGCTA
CAGCATGGGCTCAAGGGGGGCTTGCTGCCGTGGAACCTCCCGATTCTTTTGAAAGCCATGCACAAGATACTCTCAAGGCT
GGACACTATTGCGATCCCTTGATGGTTCGAGAAATGGTACAGCAGGCACCTGCAGTAATCGATGAACTCCGATCCTGGGG
AATGCCGTTTAGTCCAGTTTTGCACCGCGAAGGAGGCCATGCTGTTGCAAGGGTTTATAACACTGGGGATGGTGCCACTG
GCGCTGCAATGCATGCAGTTTTATTGACCCGCGCAAAAAAAATGGGAATCAAAATCACAGAGCACTTTAGAGCTGTAGAT
ATTCTTACTAACGGCACAGCCGCGTGCGGCATTCGTGTACAGGATGAGAATGGCCGTATCGGGGAGCTACTAACAAATAT
CGTGGTTTTGGCCACTGGTGGAATCGGTAGAATTTTCGGGCGTACTACCAATCCAGTAACGGCTACTGGCGACGGCCTAG
CCATGGCCATTCGCGCAGGCGCTCGTACTAAAAATATGCGATACGTCCAATTTCACCCGACTGTTCTTGATTCCCCCAGT
GGGGTACTTATCTCCGAAGCAGTGCGAGGAGCTGGCGCGGTGATTGAATTATTTGATGGAACAACGATTCCATTGGCACC
GAGAGATATTGTCTCAGCAGCGATCTGGAAAGCTGGTGGTCATGCCATCCTGAACTGCGAAAAAGTTGATTGGACGCAAT
TCCCAGCCATTGCACGACAACTTGAGGGGTATGACCTAGATCGCATTCCCATTGCTCCAGGCGCACATTATCACTGTGGC
GGTGTGGTCGCAAATATTGACGGGAGCACATCAATAGATGGTTTGTATGCGGTTGGTGAGGTTGCGTGCACTGGGTTGCA
TGGCAGTAATAGATTAGCTTCCAATTCCCTTACTGAGGCAGTAACTATGGGGCGTCTCGTTGCAACTGGGCTGCATAAAA
ACCATGAATACACAAAACCCACTCCGCGTGCGCGCGTTATGGAAAATCTCGATGCATGTAATCTTCGTTTGGTTAAAGAA
GCGGTAGGACAGCAGCCATGGATGTTATAA

Upstream 100 bases:

>100_bases
AAAAACTAGAAAAAGCGCTAGTGGAAGGGCACCATGAGGTACACGTTGATCCGGTTTTAGCCCAACGTGCACGTGGAGCC
GTTGAGGCGATGATCACTCT

Downstream 100 bases:

>100_bases
ACAATGCCCTTAATGAAGATCTATGTTATGGTCCTGACGTCACAACAGAAGCAATTTTTGGGCTAGAAAAAGCCGAGGTG
CAATTTGCAGCACGTGCCCA

Product: putative aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MIFEVDLGSTDYIEEHDAVIVGGGAAGLRSAISLAERGISPIILTKTTVDECATAWAQGGLAAVEPPDSFESHAQDTLKA
GHYCDPLMVREMVQQAPAVIDELRSWGMPFSPVLHREGGHAVARVYNTGDGATGAAMHAVLLTRAKKMGIKITEHFRAVD
ILTNGTAACGIRVQDENGRIGELLTNIVVLATGGIGRIFGRTTNPVTATGDGLAMAIRAGARTKNMRYVQFHPTVLDSPS
GVLISEAVRGAGAVIELFDGTTIPLAPRDIVSAAIWKAGGHAILNCEKVDWTQFPAIARQLEGYDLDRIPIAPGAHYHCG
GVVANIDGSTSIDGLYAVGEVACTGLHGSNRLASNSLTEAVTMGRLVATGLHKNHEYTKPTPRARVMENLDACNLRLVKE
AVGQQPWML

Sequences:

>Translated_409_residues
MIFEVDLGSTDYIEEHDAVIVGGGAAGLRSAISLAERGISPIILTKTTVDECATAWAQGGLAAVEPPDSFESHAQDTLKA
GHYCDPLMVREMVQQAPAVIDELRSWGMPFSPVLHREGGHAVARVYNTGDGATGAAMHAVLLTRAKKMGIKITEHFRAVD
ILTNGTAACGIRVQDENGRIGELLTNIVVLATGGIGRIFGRTTNPVTATGDGLAMAIRAGARTKNMRYVQFHPTVLDSPS
GVLISEAVRGAGAVIELFDGTTIPLAPRDIVSAAIWKAGGHAILNCEKVDWTQFPAIARQLEGYDLDRIPIAPGAHYHCG
GVVANIDGSTSIDGLYAVGEVACTGLHGSNRLASNSLTEAVTMGRLVATGLHKNHEYTKPTPRARVMENLDACNLRLVKE
AVGQQPWML
>Mature_409_residues
MIFEVDLGSTDYIEEHDAVIVGGGAAGLRSAISLAERGISPIILTKTTVDECATAWAQGGLAAVEPPDSFESHAQDTLKA
GHYCDPLMVREMVQQAPAVIDELRSWGMPFSPVLHREGGHAVARVYNTGDGATGAAMHAVLLTRAKKMGIKITEHFRAVD
ILTNGTAACGIRVQDENGRIGELLTNIVVLATGGIGRIFGRTTNPVTATGDGLAMAIRAGARTKNMRYVQFHPTVLDSPS
GVLISEAVRGAGAVIELFDGTTIPLAPRDIVSAAIWKAGGHAILNCEKVDWTQFPAIARQLEGYDLDRIPIAPGAHYHCG
GVVANIDGSTSIDGLYAVGEVACTGLHGSNRLASNSLTEAVTMGRLVATGLHKNHEYTKPTPRARVMENLDACNLRLVKE
AVGQQPWML

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=399, Percent_Identity=31.328320802005, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1788928, Length=405, Percent_Identity=38.5185185185185, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1790597, Length=374, Percent_Identity=32.8877005347594, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786942, Length=422, Percent_Identity=31.7535545023697, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17550100, Length=398, Percent_Identity=30.9045226130653, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17505833, Length=400, Percent_Identity=31.5, Blast_Score=135, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6322416, Length=450, Percent_Identity=33.5555555555556, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6322701, Length=414, Percent_Identity=33.0917874396135, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320788, Length=302, Percent_Identity=27.8145695364238, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17137288, Length=450, Percent_Identity=31.3333333333333, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24655642, Length=450, Percent_Identity=31.3333333333333, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24655647, Length=450, Percent_Identity=31.3333333333333, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24663005, Length=419, Percent_Identity=28.8782816229117, Blast_Score=124, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 43326; Mature: 43326

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFEVDLGSTDYIEEHDAVIVGGGAAGLRSAISLAERGISPIILTKTTVDECATAWAQGG
CEEEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCC
LAAVEPPDSFESHAQDTLKAGHYCDPLMVREMVQQAPAVIDELRSWGMPFSPVLHREGGH
EEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
AVARVYNTGDGATGAAMHAVLLTRAKKMGIKITEHFRAVDILTNGTAACGIRVQDENGRI
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHEEEEEEECCCEEEEEEEECCCCCH
GELLTNIVVLATGGIGRIFGRTTNPVTATGDGLAMAIRAGARTKNMRYVQFHPTVLDSPS
HHHHHCEEEEECCCHHHHCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEECCEEECCCC
GVLISEAVRGAGAVIELFDGTTIPLAPRDIVSAAIWKAGGHAILNCEKVDWTQFPAIARQ
CCHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
LEGYDLDRIPIAPGAHYHCGGVVANIDGSTSIDGLYAVGEVACTGLHGSNRLASNSLTEA
HCCCCCCCCCCCCCCCEECCCEEEECCCCCCCCHHHEECHHEEECCCCCCCCHHHHHHHH
VTMGRLVATGLHKNHEYTKPTPRARVMENLDACNLRLVKEAVGQQPWML
HHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIFEVDLGSTDYIEEHDAVIVGGGAAGLRSAISLAERGISPIILTKTTVDECATAWAQGG
CEEEEECCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCC
LAAVEPPDSFESHAQDTLKAGHYCDPLMVREMVQQAPAVIDELRSWGMPFSPVLHREGGH
EEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
AVARVYNTGDGATGAAMHAVLLTRAKKMGIKITEHFRAVDILTNGTAACGIRVQDENGRI
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHEEEEEEECCCEEEEEEEECCCCCH
GELLTNIVVLATGGIGRIFGRTTNPVTATGDGLAMAIRAGARTKNMRYVQFHPTVLDSPS
HHHHHCEEEEECCCHHHHCCCCCCCEEECCCCEEEEEECCCCCCCEEEEEECCEEECCCC
GVLISEAVRGAGAVIELFDGTTIPLAPRDIVSAAIWKAGGHAILNCEKVDWTQFPAIARQ
CCHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
LEGYDLDRIPIAPGAHYHCGGVVANIDGSTSIDGLYAVGEVACTGLHGSNRLASNSLTEA
HCCCCCCCCCCCCCCCEECCCEEEECCCCCCCCHHHEECHHEEECCCCCCCCHHHHHHHH
VTMGRLVATGLHKNHEYTKPTPRARVMENLDACNLRLVKEAVGQQPWML
HHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]