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The map label for this gene is nadA [H]

Identifier: 38234793

GI number: 38234793

Start: 2349511

End: 2350428

Strand: Direct

Name: nadA [H]

Synonym: DIP2257

Alternate gene names: 38234793

Gene position: 2349511-2350428 (Clockwise)

Preceding gene: 38234788

Following gene: 38234794

Centisome position: 94.41

GC content: 49.02

Gene sequence:

>918_bases
ATGAATTTGATGGATCTAGCTAATGAGCACGATGCTCTCATCCTGGCTCACAACTACCAGACGCCCGAGATTCAAGATGT
GGCACACCACGTCGGAGATTCTCTAGCCTTGGCAAAAATCGCCGCCGAATCTCAAGCAAGCACAATTGTGTTGTGCGGAG
TTTATTTCATGGCTGAGACTACAAAGATTCTCAGTCCCGAAAAACGTGTAATTATCCCCGAACCTGAAGCTGGATGTTCG
TTGGCGTCTTCAATTACCGCAGAACAACTACGCGCATGGAAAGCTGAACATCCTGAAGCTGCCGTAGTGGCGTACGTCAA
TACCACGGCAGAAGTTAAGGCTCTCAGCGACGTCTGTTGCACCTCTTCAAACGCTGTGCGCGTGGTTGAATCAATCGACC
CTGATCGCGATATCCTATTCCTTCCGGATCAATTTCTAGGAGCCCATGTTCAGCGCGAAACTGGACGAAAAAACATTCAT
GTGTGGCTTGGGGAATGCCATGTTCATGCCGATATATCTCCGACACATATTACGGAAATGGCACATAACAACCCGCAAGC
AGACCTATATGTCCATCCCGAATGCGGGTGTACAACCTCGGCGCTCTGGCTAGCTAGCCAAGGGGATATTCCACAAGCAA
GAATCCTCTCTACTGGGGGGATGATGGAGGCAGCACGAAAAACTGCCGCATCCACAGTGCTAGTAGCAACAGAAATAGGG
ATGCTGCATCAACTACGTAAAGCCAACACAGCGACTGATTTCATTCCAGTCAATCCTTATGCTGCCTGCCCATTTATGCA
AATGATAACAATGGAAAAACTAGAAAAAGCGCTAGTGGAAGGGCACCATGAGGTACACGTTGATCCGGTTTTAGCCCAAC
GTGCACGTGGAGCCGTTGAGGCGATGATCACTCTATGA

Upstream 100 bases:

>100_bases
GTCCCATTAGCATCGCGCAGTGGTCGAGATTTTGTAGAGCCCATAAAGCAGATGATACTGTAAAAACACTTATCGCCCGA
CAGTCGAAAAGGGGCTATCC

Downstream 100 bases:

>100_bases
TCTTCGAAGTTGATCTTGGCTCTACCGATTATATTGAAGAGCATGATGCCGTTATAGTAGGCGGCGGGGCAGCAGGGCTT
CGCTCTGCGATTAGTTTAGC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNLMDLANEHDALILAHNYQTPEIQDVAHHVGDSLALAKIAAESQASTIVLCGVYFMAETTKILSPEKRVIIPEPEAGCS
LASSITAEQLRAWKAEHPEAAVVAYVNTTAEVKALSDVCCTSSNAVRVVESIDPDRDILFLPDQFLGAHVQRETGRKNIH
VWLGECHVHADISPTHITEMAHNNPQADLYVHPECGCTTSALWLASQGDIPQARILSTGGMMEAARKTAASTVLVATEIG
MLHQLRKANTATDFIPVNPYAACPFMQMITMEKLEKALVEGHHEVHVDPVLAQRARGAVEAMITL

Sequences:

>Translated_305_residues
MNLMDLANEHDALILAHNYQTPEIQDVAHHVGDSLALAKIAAESQASTIVLCGVYFMAETTKILSPEKRVIIPEPEAGCS
LASSITAEQLRAWKAEHPEAAVVAYVNTTAEVKALSDVCCTSSNAVRVVESIDPDRDILFLPDQFLGAHVQRETGRKNIH
VWLGECHVHADISPTHITEMAHNNPQADLYVHPECGCTTSALWLASQGDIPQARILSTGGMMEAARKTAASTVLVATEIG
MLHQLRKANTATDFIPVNPYAACPFMQMITMEKLEKALVEGHHEVHVDPVLAQRARGAVEAMITL
>Mature_305_residues
MNLMDLANEHDALILAHNYQTPEIQDVAHHVGDSLALAKIAAESQASTIVLCGVYFMAETTKILSPEKRVIIPEPEAGCS
LASSITAEQLRAWKAEHPEAAVVAYVNTTAEVKALSDVCCTSSNAVRVVESIDPDRDILFLPDQFLGAHVQRETGRKNIH
VWLGECHVHADISPTHITEMAHNNPQADLYVHPECGCTTSALWLASQGDIPQARILSTGGMMEAARKTAASTVLVATEIG
MLHQLRKANTATDFIPVNPYAACPFMQMITMEKLEKALVEGHHEVHVDPVLAQRARGAVEAMITL

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=316, Percent_Identity=34.8101265822785, Blast_Score=167, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 33121; Mature: 33121

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLMDLANEHDALILAHNYQTPEIQDVAHHVGDSLALAKIAAESQASTIVLCGVYFMAET
CCCHHCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEEHHHHHHHH
TKILSPEKRVIIPEPEAGCSLASSITAEQLRAWKAEHPEAAVVAYVNTTAEVKALSDVCC
HHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHC
TSSNAVRVVESIDPDRDILFLPDQFLGAHVQRETGRKNIHVWLGECHVHADISPTHITEM
CCCCCEEEEECCCCCCCEEECCHHHHCCHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHH
AHNNPQADLYVHPECGCTTSALWLASQGDIPQARILSTGGMMEAARKTAASTVLVATEIG
HCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHEEEECCCHHHHHHHHHHHEEEEHHHHH
MLHQLRKANTATDFIPVNPYAACPFMQMITMEKLEKALVEGHHEVHVDPVLAQRARGAVE
HHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCHHE
AMITL
EEEEC
>Mature Secondary Structure
MNLMDLANEHDALILAHNYQTPEIQDVAHHVGDSLALAKIAAESQASTIVLCGVYFMAET
CCCHHCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEEHHHHHHHH
TKILSPEKRVIIPEPEAGCSLASSITAEQLRAWKAEHPEAAVVAYVNTTAEVKALSDVCC
HHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHC
TSSNAVRVVESIDPDRDILFLPDQFLGAHVQRETGRKNIHVWLGECHVHADISPTHITEM
CCCCCEEEEECCCCCCCEEECCHHHHCCHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHH
AHNNPQADLYVHPECGCTTSALWLASQGDIPQARILSTGGMMEAARKTAASTVLVATEIG
HCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHEEEECCCHHHHHHHHHHHEEEEHHHHH
MLHQLRKANTATDFIPVNPYAACPFMQMITMEKLEKALVEGHHEVHVDPVLAQRARGAVE
HHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCHHE
AMITL
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA