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The map label for this gene is desA3 [H]

Identifier: 38233311

GI number: 38233311

Start: 679690

End: 680970

Strand: Direct

Name: desA3 [H]

Synonym: DIP0704

Alternate gene names: 38233311

Gene position: 679690-680970 (Clockwise)

Preceding gene: 38233310

Following gene: 38233314

Centisome position: 27.31

GC content: 50.43

Gene sequence:

>1281_bases
ATGGCAATCGACAACATTAAAGCGTATGTACACTTAAGTGACGCAGACATCGAAGAAATCGGTCGTCGCCTAGATCAGAT
CAAAGCAGAGGTAACGCAATCACTAGGTGCTCGGGACGTGGCCTACATCAAGCGTTTGATTCGTACCCAACGTAGCCTTG
AGGCAGCTGGTCGATTCGCGCTGTTGTTTGCGGGAAATAAGAAGTGTTGGTGGCTCGGAACAGGGTTGCTCAGCACTGCG
AAAATCCTAGAAAATCTCGAAATCGGGCATAACGTGCTTCATGGGCAATGGGATTGGATGAATGATCCCGAAATTCACTC
CACCACATGGGAGTGGGACATTGTCTGCCCATCATCACAATGGATGCACTCACATAACTTTGTTCACCACACCTACACTA
ACGTGCTGGGAATGGACAACGATGTGGGATACGGAATCTTGCGCGTCACCCGCGACCGAAAATGGACACCACTACATGCT
TTCCAACCAGCGGTGAATACCGTGCTGGCAGCGATGTTCCAGTGGGCGGTGGGGTACTACGACGTGGAACTTGGGCGCTA
TCTGACTAAACGCGCTGATTGGAATGACACAAAAGACAAATTCTGGGAGACGACGAACAAAGCAGGTCGCCAGCTTGCTC
GCGACTACGTTTTCTATCCAGCACTTGCTAGAAAGGCTTTTCCGCAGGCAGTGAAGGCAAATGCGGTTGCCAACCTAGTG
CGCTCAGTGTGGGCATATTCTGTTATCTTCTGCGGACATTTTCCTGATGAGGCCGAGACGTTTACCAAAGAACAGTTTAA
AAACGAGGACCACAATCAGTGGTATCTACGCCAAATGCTGGGGTCTGCAAACTTCTATGGCGGCAAGTTGCTCACCATCA
TGTCGGGCAATTTGAATTACCAGATTGAACATCACCTATTCCCAGATATGCCATCGAATCGTCTGGCAGAAGTGGGAGAG
AAAGTGCGTGCGCTGTGCGACGAATACGATCTACCATACAACGTCGATTCTTTCCCAGCACAGTTGTTCAAGGTGCAAAA
AACACTGCTCAAGCTCACCCTTCCCAATAAGTACTTAGTGGCGAGCCCAGATAATGCCCCTGAGGTGCGCTCGAACCGAG
CATTTTCGCAAAACCCTGAGATTGAAAATCAACTGGCAGGCGGAAGCAACGGAAGCGGCTTACGCACGGGCCTAAAACTA
CTCAAACGCCTGCGCCCGAGTATCAAAGATGCCATCTTGATCTATTCAGGGCGCAAGCCGCGGGGAAATCAACAGCGCTG
A

Upstream 100 bases:

>100_bases
TCGTAACCGGTGAGACTCATGAGCCGGGGTCACGTATTCGTACCTGCGTGTGCGTAGCTGCAGGTGACATCACTATCGAA
GCATAGGACGGAACAATTTC

Downstream 100 bases:

>100_bases
TCTATTCCCAATCCACGTTGGTGCGCAAGGCGCCGAGCAACTTGCGTACCGCGACAACGCGGCGACCAGTGGGGGAGTCT
GCGTCGAAAGTGTCGAGGAC

Product: hypothetical protein

Products: NA

Alternate protein names: Delta(9)-desaturase; Stearoyl-CoA desaturase [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MAIDNIKAYVHLSDADIEEIGRRLDQIKAEVTQSLGARDVAYIKRLIRTQRSLEAAGRFALLFAGNKKCWWLGTGLLSTA
KILENLEIGHNVLHGQWDWMNDPEIHSTTWEWDIVCPSSQWMHSHNFVHHTYTNVLGMDNDVGYGILRVTRDRKWTPLHA
FQPAVNTVLAAMFQWAVGYYDVELGRYLTKRADWNDTKDKFWETTNKAGRQLARDYVFYPALARKAFPQAVKANAVANLV
RSVWAYSVIFCGHFPDEAETFTKEQFKNEDHNQWYLRQMLGSANFYGGKLLTIMSGNLNYQIEHHLFPDMPSNRLAEVGE
KVRALCDEYDLPYNVDSFPAQLFKVQKTLLKLTLPNKYLVASPDNAPEVRSNRAFSQNPEIENQLAGGSNGSGLRTGLKL
LKRLRPSIKDAILIYSGRKPRGNQQR

Sequences:

>Translated_426_residues
MAIDNIKAYVHLSDADIEEIGRRLDQIKAEVTQSLGARDVAYIKRLIRTQRSLEAAGRFALLFAGNKKCWWLGTGLLSTA
KILENLEIGHNVLHGQWDWMNDPEIHSTTWEWDIVCPSSQWMHSHNFVHHTYTNVLGMDNDVGYGILRVTRDRKWTPLHA
FQPAVNTVLAAMFQWAVGYYDVELGRYLTKRADWNDTKDKFWETTNKAGRQLARDYVFYPALARKAFPQAVKANAVANLV
RSVWAYSVIFCGHFPDEAETFTKEQFKNEDHNQWYLRQMLGSANFYGGKLLTIMSGNLNYQIEHHLFPDMPSNRLAEVGE
KVRALCDEYDLPYNVDSFPAQLFKVQKTLLKLTLPNKYLVASPDNAPEVRSNRAFSQNPEIENQLAGGSNGSGLRTGLKL
LKRLRPSIKDAILIYSGRKPRGNQQR
>Mature_425_residues
AIDNIKAYVHLSDADIEEIGRRLDQIKAEVTQSLGARDVAYIKRLIRTQRSLEAAGRFALLFAGNKKCWWLGTGLLSTAK
ILENLEIGHNVLHGQWDWMNDPEIHSTTWEWDIVCPSSQWMHSHNFVHHTYTNVLGMDNDVGYGILRVTRDRKWTPLHAF
QPAVNTVLAAMFQWAVGYYDVELGRYLTKRADWNDTKDKFWETTNKAGRQLARDYVFYPALARKAFPQAVKANAVANLVR
SVWAYSVIFCGHFPDEAETFTKEQFKNEDHNQWYLRQMLGSANFYGGKLLTIMSGNLNYQIEHHLFPDMPSNRLAEVGEK
VRALCDEYDLPYNVDSFPAQLFKVQKTLLKLTLPNKYLVASPDNAPEVRSNRAFSQNPEIENQLAGGSNGSGLRTGLKLL
KRLRPSIKDAILIYSGRKPRGNQQR

Specific function: Desaturates stearoyl-CoA to form oleoyl-CoA [H]

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Probable). Note=Has been shown to be membrane-associated but no reliable trans-membrane regions are predicted by bioinformatics tools [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Homo sapiens, GI13375616, Length=246, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: NA

Molecular weight: Translated: 48751; Mature: 48620

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDNIKAYVHLSDADIEEIGRRLDQIKAEVTQSLGARDVAYIKRLIRTQRSLEAAGRFA
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEE
LLFAGNKKCWWLGTGLLSTAKILENLEIGHNVLHGQWDWMNDPEIHSTTWEWDIVCPSSQ
EEEECCCEEEEEECHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCEEEEEECCCHH
WMHSHNFVHHTYTNVLGMDNDVGYGILRVTRDRKWTPLHAFQPAVNTVLAAMFQWAVGYY
HHHHCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DVELGRYLTKRADWNDTKDKFWETTNKAGRQLARDYVFYPALARKAFPQAVKANAVANLV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVWAYSVIFCGHFPDEAETFTKEQFKNEDHNQWYLRQMLGSANFYGGKLLTIMSGNLNY
HHHHHHHHHEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCEE
QIEHHLFPDMPSNRLAEVGEKVRALCDEYDLPYNVDSFPAQLFKVQKTLLKLTLPNKYLV
EEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEECCCCEEE
ASPDNAPEVRSNRAFSQNPEIENQLAGGSNGSGLRTGLKLLKRLRPSIKDAILIYSGRKP
ECCCCCCCHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHCEEEEEECCCC
RGNQQR
CCCCCC
>Mature Secondary Structure 
AIDNIKAYVHLSDADIEEIGRRLDQIKAEVTQSLGARDVAYIKRLIRTQRSLEAAGRFA
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEE
LLFAGNKKCWWLGTGLLSTAKILENLEIGHNVLHGQWDWMNDPEIHSTTWEWDIVCPSSQ
EEEECCCEEEEEECHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCEEEEEECCCHH
WMHSHNFVHHTYTNVLGMDNDVGYGILRVTRDRKWTPLHAFQPAVNTVLAAMFQWAVGYY
HHHHCCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DVELGRYLTKRADWNDTKDKFWETTNKAGRQLARDYVFYPALARKAFPQAVKANAVANLV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVWAYSVIFCGHFPDEAETFTKEQFKNEDHNQWYLRQMLGSANFYGGKLLTIMSGNLNY
HHHHHHHHHEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCEE
QIEHHLFPDMPSNRLAEVGEKVRALCDEYDLPYNVDSFPAQLFKVQKTLLKLTLPNKYLV
EEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEECCCCEEE
ASPDNAPEVRSNRAFSQNPEIENQLAGGSNGSGLRTGLKLLKRLRPSIKDAILIYSGRKP
ECCCCCCCHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHCEEEEEECCCC
RGNQQR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]