Click here to switch to the map view.

The map label for this gene is fhuG [H]

Identifier: 38233192

GI number: 38233192

Start: 551335

End: 552324

Strand: Direct

Name: fhuG [H]

Synonym: DIP0583

Alternate gene names: 38233192

Gene position: 551335-552324 (Clockwise)

Preceding gene: 38233191

Following gene: 38233193

Centisome position: 22.15

GC content: 58.59

Gene sequence:

>990_bases
ATGAAATCCCGTGCTGTATTGGCGAGCCTGTTTGCCTGCGGGATAGTTGTTGTGGCTATCGTATGGTGGCGCATATCTGG
GGTATCGGCACCAGCCGATGCCCCTCAGCTATTCCCAGAATTGCTCAGTCTTGCCCGCGATCGCCTTCTCGCCGCCCTTA
TCGTTGGAGCATGCCTAGGTGTTGGCGGCGTCCTGCTGCGTACCGCCACCTCTAATCCATTAGCGGATCCCCACATCACT
GGAGTCAACGCCGGAGCCGCGTTTGGTGCAGTAGCTTCGAGCTTTATCACCGGTTCTGCTACCGGCGCCTATCTATTGCC
TGGGGCGCTCATCGGTGGGGCCTTGGCCGCAGGTTTTACCATCTCGTTGAGCGTGCGCGGTGCCGGACCTGAACTCAGTG
GCGCCCATGCAGTGCAAAAAATGGTGCTGCTGGGTATTGCTGTCTCGGCAGTATTTAGTGCCTTGACCGCCATCTTTTTG
GTTCTCGATGAAGCACAATTGACTACCATTTTGGCGTGGCTTAATGGTCGCCTCGCCGGAGTACGTATGGGCGATCTGTG
GCCAGCGTTGTGTGCTTTCGTGATGCTGTTTCCGGTACTTGTTGCTGGGGGAAGAGCTTTCGATTCTCTCGGGACAGGAG
ACGTCGTCAGTCGCGCGATTGGTGCGCATCCGGCGCGGGTGCGGGCCTTGGCGATTGTGGCCTCGGTGGTGCTAACCGCG
ACATGTGTAGCTGCCGCCGGCCCTATTGGTTTTTTGGGCTTGCTGGCTGCGGTAGTGGCACAACGTATCGCTGGGCGAGC
GCATCGACGTAGCCTTGTGGTCGCTGCTGCTGTTGGCGCCACCACACTGCTAGTCGCCGATACTGTCGGGCAAGCATTGT
GGGCTCCTGTGGAAACGCCCGTGGGAATCTTGACAGGTATTGCAGGTGTCCCGCTATTGCTGTGGGGGATTCGTTCGCTG
GGGTCGGGAACGAAGAGGCAGGGTAAGTAA

Upstream 100 bases:

>100_bases
AGATACGTGGTCGCGTTCGCGTGGCCCGCTGGCTGCAGAAGCCATGCTCGATCAGATCATCAACTCTTAAAAACACTGAC
TATTTGTTAACTGTAGGTTT

Downstream 100 bases:

>100_bases
TGGCGCAGAAAAAGACATTTGTTATCGCTCTTGTTGTGAGTACTGCTTGCTTGGTGTTGGCATGCTTGTTGGGCATGGCT
ATTGGGGCGGTGCAAAAATC

Product: putative iron transport system membrane protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKSRAVLASLFACGIVVVAIVWWRISGVSAPADAPQLFPELLSLARDRLLAALIVGACLGVGGVLLRTATSNPLADPHIT
GVNAGAAFGAVASSFITGSATGAYLLPGALIGGALAAGFTISLSVRGAGPELSGAHAVQKMVLLGIAVSAVFSALTAIFL
VLDEAQLTTILAWLNGRLAGVRMGDLWPALCAFVMLFPVLVAGGRAFDSLGTGDVVSRAIGAHPARVRALAIVASVVLTA
TCVAAAGPIGFLGLLAAVVAQRIAGRAHRRSLVVAAAVGATTLLVADTVGQALWAPVETPVGILTGIAGVPLLLWGIRSL
GSGTKRQGK

Sequences:

>Translated_329_residues
MKSRAVLASLFACGIVVVAIVWWRISGVSAPADAPQLFPELLSLARDRLLAALIVGACLGVGGVLLRTATSNPLADPHIT
GVNAGAAFGAVASSFITGSATGAYLLPGALIGGALAAGFTISLSVRGAGPELSGAHAVQKMVLLGIAVSAVFSALTAIFL
VLDEAQLTTILAWLNGRLAGVRMGDLWPALCAFVMLFPVLVAGGRAFDSLGTGDVVSRAIGAHPARVRALAIVASVVLTA
TCVAAAGPIGFLGLLAAVVAQRIAGRAHRRSLVVAAAVGATTLLVADTVGQALWAPVETPVGILTGIAGVPLLLWGIRSL
GSGTKRQGK
>Mature_329_residues
MKSRAVLASLFACGIVVVAIVWWRISGVSAPADAPQLFPELLSLARDRLLAALIVGACLGVGGVLLRTATSNPLADPHIT
GVNAGAAFGAVASSFITGSATGAYLLPGALIGGALAAGFTISLSVRGAGPELSGAHAVQKMVLLGIAVSAVFSALTAIFL
VLDEAQLTTILAWLNGRLAGVRMGDLWPALCAFVMLFPVLVAGGRAFDSLGTGDVVSRAIGAHPARVRALAIVASVVLTA
TCVAAAGPIGFLGLLAAVVAQRIAGRAHRRSLVVAAAVGATTLLVADTVGQALWAPVETPVGILTGIAGVPLLLWGIRSL
GSGTKRQGK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=33.2142857142857, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790741, Length=294, Percent_Identity=33.6734693877551, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=28.2685512367491, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786805, Length=259, Percent_Identity=32.046332046332, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786804, Length=277, Percent_Identity=32.4909747292419, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788004, Length=273, Percent_Identity=31.5018315018315, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32937; Mature: 32937

Theoretical pI: Translated: 11.29; Mature: 11.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRAVLASLFACGIVVVAIVWWRISGVSAPADAPQLFPELLSLARDRLLAALIVGACLG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGVLLRTATSNPLADPHITGVNAGAAFGAVASSFITGSATGAYLLPGALIGGALAAGFT
HHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCEE
ISLSVRGAGPELSGAHAVQKMVLLGIAVSAVFSALTAIFLVLDEAQLTTILAWLNGRLAG
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VRMGDLWPALCAFVMLFPVLVAGGRAFDSLGTGDVVSRAIGAHPARVRALAIVASVVLTA
EEHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TCVAAAGPIGFLGLLAAVVAQRIAGRAHRRSLVVAAAVGATTLLVADTVGQALWAPVETP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VGILTGIAGVPLLLWGIRSLGSGTKRQGK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKSRAVLASLFACGIVVVAIVWWRISGVSAPADAPQLFPELLSLARDRLLAALIVGACLG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGVLLRTATSNPLADPHITGVNAGAAFGAVASSFITGSATGAYLLPGALIGGALAAGFT
HHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCEE
ISLSVRGAGPELSGAHAVQKMVLLGIAVSAVFSALTAIFLVLDEAQLTTILAWLNGRLAG
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VRMGDLWPALCAFVMLFPVLVAGGRAFDSLGTGDVVSRAIGAHPARVRALAIVASVVLTA
EEHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
TCVAAAGPIGFLGLLAAVVAQRIAGRAHRRSLVVAAAVGATTLLVADTVGQALWAPVETP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VGILTGIAGVPLLLWGIRSLGSGTKRQGK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]