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The map label for this gene is yfmE [H]

Identifier: 38233193

GI number: 38233193

Start: 552324

End: 553307

Strand: Direct

Name: yfmE [H]

Synonym: DIP0584

Alternate gene names: 38233193

Gene position: 552324-553307 (Clockwise)

Preceding gene: 38233192

Following gene: 38233194

Centisome position: 22.19

GC content: 58.13

Gene sequence:

>984_bases
ATGGCGCAGAAAAAGACATTTGTTATCGCTCTTGTTGTGAGTACTGCTTGCTTGGTGTTGGCATGCTTGTTGGGCATGGC
TATTGGGGCGGTGCAAAAATCTCTGCCCGAGGTTGTTGCTGGGCTCATCAGTGGCGAAAGCTTGTATTGGCGCTACCGCA
TGCCGCGCATCGTGGTGGGAGTACTAGCGGGTGTTGGTATGGCAGTATCAGGCAGTTTGCTGCAGACGTCGTTACGCAAC
CCGCTTGCGGCCCCCGATACGCTGGGGATCACGGCCGGTGGTGGGCTCGCTGCCGTAGTGGCGTTGCTTGGCTTTGGGCA
GCTGTCGCCGCTTGCGCTCACCCCGATCGCCTTTGTGGGATCGCTGCTCGGTGCCGTGGTGGTTTTGTTGGCAGCAGGGA
AGTCGATCTTTGATCCGGCACGGTTGGCGCTTACAGGTGTTGCCGTGTCTGTGGGGCTTGCCGCCGTCACCCAACTGCTG
TTGGTACGCGTTGCCCCTGAAGCGGGTGCGGCGATGACGTGGCTTAAAGGCTCGCTTTATGCCAGAACGATGGCCGATGC
GATGACAGTTGCCCCCGTAGTTGTCATCGGATGCGTTGTGGCTTTAATCGGTGCAAAGCACTTTAATGCATTAGCGCTTG
ACGACGCGATGATGACGAGCATTGGCGTGCGTAGTCGAGCCTTGCGGTTAGTGACACTGGGCGTAGCCATCGCATGTGGC
TCTGCTGCCGTGGCTGCGGCAGGCGTGCTCGGATTCGTCGGATTGATTATTCCGCATGCCGCGAAGTTACTGGTAGGGCA
GGCCTTATCGCGCCAAATTCCTGTGGCTGCGGTGGCGGGTGCTGCGCTAGTGGTTGCTACCGATGCGGTCGGCCGATGGG
TATTCGCGCCAACAGAAATCCCGGTAGGCGCGCTCATCGCGATCGTTGGTGCGCCGTACTTTATTTACTTAGTTCATCGC
GTGACAAGTGTGAAGAGGAAATAA

Upstream 100 bases:

>100_bases
TGGAAACGCCCGTGGGAATCTTGACAGGTATTGCAGGTGTCCCGCTATTGCTGTGGGGGATTCGTTCGCTGGGGTCGGGA
ACGAAGAGGCAGGGTAAGTA

Downstream 100 bases:

>100_bases
AACATGGACCGTAATTCCACAGCAACAATGCCGCAACAGTCCTTGGGCTGTATGTCGATGTCTGCAGGGTACGGGGCAGA
ATTGATTGTTCGAGATGTTT

Product: putative iron transport system membrane protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAQKKTFVIALVVSTACLVLACLLGMAIGAVQKSLPEVVAGLISGESLYWRYRMPRIVVGVLAGVGMAVSGSLLQTSLRN
PLAAPDTLGITAGGGLAAVVALLGFGQLSPLALTPIAFVGSLLGAVVVLLAAGKSIFDPARLALTGVAVSVGLAAVTQLL
LVRVAPEAGAAMTWLKGSLYARTMADAMTVAPVVVIGCVVALIGAKHFNALALDDAMMTSIGVRSRALRLVTLGVAIACG
SAAVAAAGVLGFVGLIIPHAAKLLVGQALSRQIPVAAVAGAALVVATDAVGRWVFAPTEIPVGALIAIVGAPYFIYLVHR
VTSVKRK

Sequences:

>Translated_327_residues
MAQKKTFVIALVVSTACLVLACLLGMAIGAVQKSLPEVVAGLISGESLYWRYRMPRIVVGVLAGVGMAVSGSLLQTSLRN
PLAAPDTLGITAGGGLAAVVALLGFGQLSPLALTPIAFVGSLLGAVVVLLAAGKSIFDPARLALTGVAVSVGLAAVTQLL
LVRVAPEAGAAMTWLKGSLYARTMADAMTVAPVVVIGCVVALIGAKHFNALALDDAMMTSIGVRSRALRLVTLGVAIACG
SAAVAAAGVLGFVGLIIPHAAKLLVGQALSRQIPVAAVAGAALVVATDAVGRWVFAPTEIPVGALIAIVGAPYFIYLVHR
VTSVKRK
>Mature_326_residues
AQKKTFVIALVVSTACLVLACLLGMAIGAVQKSLPEVVAGLISGESLYWRYRMPRIVVGVLAGVGMAVSGSLLQTSLRNP
LAAPDTLGITAGGGLAAVVALLGFGQLSPLALTPIAFVGSLLGAVVVLLAAGKSIFDPARLALTGVAVSVGLAAVTQLLL
VRVAPEAGAAMTWLKGSLYARTMADAMTVAPVVVIGCVVALIGAKHFNALALDDAMMTSIGVRSRALRLVTLGVAIACGS
AAVAAAGVLGFVGLIIPHAAKLLVGQALSRQIPVAAVAGAALVVATDAVGRWVFAPTEIPVGALIAIVGAPYFIYLVHRV
TSVKRK

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=317, Percent_Identity=35.0157728706625, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1786347, Length=277, Percent_Identity=32.4909747292419, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790741, Length=278, Percent_Identity=33.4532374100719, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=30.6060606060606, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786805, Length=273, Percent_Identity=34.7985347985348, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=31.3167259786477, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32910; Mature: 32779

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKKTFVIALVVSTACLVLACLLGMAIGAVQKSLPEVVAGLISGESLYWRYRMPRIVVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
VLAGVGMAVSGSLLQTSLRNPLAAPDTLGITAGGGLAAVVALLGFGQLSPLALTPIAFVG
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCHHHHHHHHHH
SLLGAVVVLLAAGKSIFDPARLALTGVAVSVGLAAVTQLLLVRVAPEAGAAMTWLKGSLY
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
ARTMADAMTVAPVVVIGCVVALIGAKHFNALALDDAMMTSIGVRSRALRLVTLGVAIACG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAAVAAAGVLGFVGLIIPHAAKLLVGQALSRQIPVAAVAGAALVVATDAVGRWVFAPTEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHEEEEHHHCCEEECCCCC
PVGALIAIVGAPYFIYLVHRVTSVKRK
CHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQKKTFVIALVVSTACLVLACLLGMAIGAVQKSLPEVVAGLISGESLYWRYRMPRIVVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH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CHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]