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The map label for this gene is yfmC [H]

Identifier: 38233191

GI number: 38233191

Start: 550408

End: 551304

Strand: Direct

Name: yfmC [H]

Synonym: DIP0582

Alternate gene names: 38233191

Gene position: 550408-551304 (Clockwise)

Preceding gene: 38233190

Following gene: 38233192

Centisome position: 22.12

GC content: 53.85

Gene sequence:

>897_bases
ATGCATGTAAATCCATTAATCTCTGTTGCGCGTTCTAAAGCCTCGGCTTTGTTCGCAGCACTCGCGCTGGTTCTCGTCGT
CACGCTAACCCTTGCTGGATGTTCCTCTGACAAGTCAGGGGAGACGACCGCAGAGGCGAAAAAAGACCCATCGAGTATCC
GCGTCGTGGCCTTGGACTGGCGCTATGAGGAAATCCTTCATGCATTAGGTATCACCCCAGTAGGCATTGTGGAGATCGGC
AAGTCCAAGGAGCCTCAGACACTAAAAGGCGAGCTGGAGGGTGTGACGTCGGTAGGCCAAGCAAAGCAGCCAAACTTGGA
AGTCATCCAGTCGCTAGAGCCTGACCTAATTCTGGCAAGCCCTACTCGCCAAGCAGCGATCATGGATCAGCTCAAAGAGA
TCGCTCCCACCCACGCCTACGGTGATACCTCCTACACCGAAGTTCTAGACGCCATGGATGACATTGCCACCAAGGTAGGC
GCAGAAGACAAAGCTAAGGAAGTCCGTACCCGTATCGAGTCCAAGATTGCCCAGGCGAAAAATAAAGTAGAGCCAGGTAC
CCGCACCGCACTGATCGGTTGGTCCAAGAACACCCTCTACACCTGGGTGAAAGATTCCTTTGCCGGATCCCTACTGACCG
CCGCTGGATACGAATACGGCTACGACGGGGAGAAGTCTGCCATTGAATCGAAGACCGACGTTGCAGAGCTCACCGGCGAC
AAACTGCCCGAGATGAAGCTTGACGTGATGTACCTCTACAACGACATCGAGGGATTCCGTTCTAGCCCTTATGCAGATGT
TGTGTCTAACATCGTCGACGTTGAGCAAGATACGTGGTCGCGTTCGCGTGGCCCGCTGGCTGCAGAAGCCATGCTCGATC
AGATCATCAACTCTTAA

Upstream 100 bases:

>100_bases
TGCCAACATGAGGCGGGGGTGCGCGTTTTGTTTCGATTAGATATCGATGGGGGCTGACCCCATTCCCCAGATAGTTAGGG
TTGTGTTACCTTGGGAAGCT

Downstream 100 bases:

>100_bases
AAACACTGACTATTTGTTAACTGTAGGTTTATGAAATCCCGTGCTGTATTGGCGAGCCTGTTTGCCTGCGGGATAGTTGT
TGTGGCTATCGTATGGTGGC

Product: putative iron transport system binding (secreted) protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate-binding protein [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MHVNPLISVARSKASALFAALALVLVVTLTLAGCSSDKSGETTAEAKKDPSSIRVVALDWRYEEILHALGITPVGIVEIG
KSKEPQTLKGELEGVTSVGQAKQPNLEVIQSLEPDLILASPTRQAAIMDQLKEIAPTHAYGDTSYTEVLDAMDDIATKVG
AEDKAKEVRTRIESKIAQAKNKVEPGTRTALIGWSKNTLYTWVKDSFAGSLLTAAGYEYGYDGEKSAIESKTDVAELTGD
KLPEMKLDVMYLYNDIEGFRSSPYADVVSNIVDVEQDTWSRSRGPLAAEAMLDQIINS

Sequences:

>Translated_298_residues
MHVNPLISVARSKASALFAALALVLVVTLTLAGCSSDKSGETTAEAKKDPSSIRVVALDWRYEEILHALGITPVGIVEIG
KSKEPQTLKGELEGVTSVGQAKQPNLEVIQSLEPDLILASPTRQAAIMDQLKEIAPTHAYGDTSYTEVLDAMDDIATKVG
AEDKAKEVRTRIESKIAQAKNKVEPGTRTALIGWSKNTLYTWVKDSFAGSLLTAAGYEYGYDGEKSAIESKTDVAELTGD
KLPEMKLDVMYLYNDIEGFRSSPYADVVSNIVDVEQDTWSRSRGPLAAEAMLDQIINS
>Mature_298_residues
MHVNPLISVARSKASALFAALALVLVVTLTLAGCSSDKSGETTAEAKKDPSSIRVVALDWRYEEILHALGITPVGIVEIG
KSKEPQTLKGELEGVTSVGQAKQPNLEVIQSLEPDLILASPTRQAAIMDQLKEIAPTHAYGDTSYTEVLDAMDDIATKVG
AEDKAKEVRTRIESKIAQAKNKVEPGTRTALIGWSKNTLYTWVKDSFAGSLLTAAGYEYGYDGEKSAIESKTDVAELTGD
KLPEMKLDVMYLYNDIEGFRSSPYADVVSNIVDVEQDTWSRSRGPLAAEAMLDQIINS

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of yfmDE (Probable) [H]

COG id: COG4594

COG function: function code P; ABC-type Fe3+-citrate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082411, Length=298, Percent_Identity=26.510067114094, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 32238; Mature: 32238

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVNPLISVARSKASALFAALALVLVVTLTLAGCSSDKSGETTAEAKKDPSSIRVVALDW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCEEEEEECC
RYEEILHALGITPVGIVEIGKSKEPQTLKGELEGVTSVGQAKQPNLEVIQSLEPDLILAS
CHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEC
PTRQAAIMDQLKEIAPTHAYGDTSYTEVLDAMDDIATKVGAEDKAKEVRTRIESKIAQAK
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
NKVEPGTRTALIGWSKNTLYTWVKDSFAGSLLTAAGYEYGYDGEKSAIESKTDVAELTGD
HCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCC
KLPEMKLDVMYLYNDIEGFRSSPYADVVSNIVDVEQDTWSRSRGPLAAEAMLDQIINS
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MHVNPLISVARSKASALFAALALVLVVTLTLAGCSSDKSGETTAEAKKDPSSIRVVALDW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCEEEEEECC
RYEEILHALGITPVGIVEIGKSKEPQTLKGELEGVTSVGQAKQPNLEVIQSLEPDLILAS
CHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEC
PTRQAAIMDQLKEIAPTHAYGDTSYTEVLDAMDDIATKVGAEDKAKEVRTRIESKIAQAK
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
NKVEPGTRTALIGWSKNTLYTWVKDSFAGSLLTAAGYEYGYDGEKSAIESKTDVAELTGD
HCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCC
KLPEMKLDVMYLYNDIEGFRSSPYADVVSNIVDVEQDTWSRSRGPLAAEAMLDQIINS
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]