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The map label for this gene is 38233190

Identifier: 38233190

GI number: 38233190

Start: 549130

End: 550275

Strand: Direct

Name: 38233190

Synonym: DIP0581

Alternate gene names: NA

Gene position: 549130-550275 (Clockwise)

Preceding gene: 38233189

Following gene: 38233191

Centisome position: 22.07

GC content: 57.42

Gene sequence:

>1146_bases
ATGCGTGATTACGTCGAAATTGGAATGGGTCGCGAGGCCCGCCGTACCTACCACCTCGACAGCGTTGCTATCGTGCCGTC
ACGACGCACCCGCTCGTCCAAGGACGTAGACACCACCTGGCACATCGATGCCTACACCTTCGACATCCCGTTCATGTCAC
ACCCCACCGATGCTCTGGCAACCCCAGACTTCGTGATCGAGATGGACAAGCAGGGTGGGCTCGGCGTGATCAACGCGGAA
GGCCTCTGGGGTCGCCACGCTGACCTCGACGCAGCAATCCAAGAAGTCATCACCGCCTACGGCGACGACGAACTCGACCT
CGGATCATGCAACCGTGCCACCAAAAAGCTCCAAGAACTCCATGCTGCTGCACTCGACACCGAACTTCTCGTCGAGCGCA
TCGCACAAGTTCGCTCATCGGGCGCAACCGTGGCAGTACGTGTATCGCCACAGCATTGCCACGAACTTGCTCCCATCCTG
ATCAAAGCAGGTGCTGAGCTCCTCATCGTGCAGGGCACCATCATCTCCGCTGAGCACGTGGAAACCAACGGTGAACCACT
CAACCTCAAGGAATTCATCGGCTCCATTGATGTTCCAGTCATCGCCGGTGGTGTTAACGATTACACCACGGCACTGCATC
TCATGCGCGCCGGTGCCGTAGGCATCATTGCCGGCGGTGGGCAAAATACTAACGATTGTGCGCTAGGAATCGACGATTCT
CTCGCAACAATTATCGCCGACGTTGCTGCCGCGCGCCGGGATTACTTGGATGAAACCGGTGGACGCTACGTGCACGTGAT
CGCAGACGGTCAAATCTTCACCTCCGGTGACGCTGTCAAGGCGATTGCATGTGGTGCCGACGCTGTGATCTTGGGTGAGC
CACTAGCTCGTGCTGCCGAAGCTGGCGGCAAGGGACTGTACTGGCCATCTGCTGCGGCACACCCTCGATTCCCTCGTGGC
GTGGTCGGCACCGCTGGTGTCATGCCGAAAACTGAGCAAGTGAGCTTGGAAGTGTTGCTACACGGCCCATCTACAAATGT
GTTCGGCGAAGAGAATTTCGTCGGCGGCCTCAAACGTGCGATGGCTAAGTGTGGCTACACTGACTTGAAGAGCTTCCAAA
AAGTGGATCTGACAGTTCAGTTCTAA

Upstream 100 bases:

>100_bases
CACCTCTGCTGGTTTGAAGGAATCACATCCTCACCACATTCAGCAGACCGTCGAAGCACCTAACTACCACTAAACCGGAA
AAACTGAAAGGTCTTCTTTC

Downstream 100 bases:

>100_bases
CTGCCGTTAACGGTTTGCTACAACGCGCACACTGCCAACATGAGGCGGGGGTGCGCGTTTTGTTTCGATTAGATATCGAT
GGGGGCTGACCCCATTCCCC

Product: inosine 5-monophosphate dehydrogenase

Products: xanthosine 5'-phosphate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MRDYVEIGMGREARRTYHLDSVAIVPSRRTRSSKDVDTTWHIDAYTFDIPFMSHPTDALATPDFVIEMDKQGGLGVINAE
GLWGRHADLDAAIQEVITAYGDDELDLGSCNRATKKLQELHAAALDTELLVERIAQVRSSGATVAVRVSPQHCHELAPIL
IKAGAELLIVQGTIISAEHVETNGEPLNLKEFIGSIDVPVIAGGVNDYTTALHLMRAGAVGIIAGGGQNTNDCALGIDDS
LATIIADVAAARRDYLDETGGRYVHVIADGQIFTSGDAVKAIACGADAVILGEPLARAAEAGGKGLYWPSAAAHPRFPRG
VVGTAGVMPKTEQVSLEVLLHGPSTNVFGEENFVGGLKRAMAKCGYTDLKSFQKVDLTVQF

Sequences:

>Translated_381_residues
MRDYVEIGMGREARRTYHLDSVAIVPSRRTRSSKDVDTTWHIDAYTFDIPFMSHPTDALATPDFVIEMDKQGGLGVINAE
GLWGRHADLDAAIQEVITAYGDDELDLGSCNRATKKLQELHAAALDTELLVERIAQVRSSGATVAVRVSPQHCHELAPIL
IKAGAELLIVQGTIISAEHVETNGEPLNLKEFIGSIDVPVIAGGVNDYTTALHLMRAGAVGIIAGGGQNTNDCALGIDDS
LATIIADVAAARRDYLDETGGRYVHVIADGQIFTSGDAVKAIACGADAVILGEPLARAAEAGGKGLYWPSAAAHPRFPRG
VVGTAGVMPKTEQVSLEVLLHGPSTNVFGEENFVGGLKRAMAKCGYTDLKSFQKVDLTVQF
>Mature_381_residues
MRDYVEIGMGREARRTYHLDSVAIVPSRRTRSSKDVDTTWHIDAYTFDIPFMSHPTDALATPDFVIEMDKQGGLGVINAE
GLWGRHADLDAAIQEVITAYGDDELDLGSCNRATKKLQELHAAALDTELLVERIAQVRSSGATVAVRVSPQHCHELAPIL
IKAGAELLIVQGTIISAEHVETNGEPLNLKEFIGSIDVPVIAGGVNDYTTALHLMRAGAVGIIAGGGQNTNDCALGIDDS
LATIIADVAAARRDYLDETGGRYVHVIADGQIFTSGDAVKAIACGADAVILGEPLARAAEAGGKGLYWPSAAAHPRFPRG
VVGTAGVMPKTEQVSLEVLLHGPSTNVFGEENFVGGLKRAMAKCGYTDLKSFQKVDLTVQF

Specific function: Unknown

COG id: COG0516

COG function: function code F; IMP dehydrogenase/GMP reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IMPDH/GMPR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001093
- InterPro:   IPR005992 [H]

Pfam domain/function: PF00478 IMPDH [H]

EC number: 1.1.1.205

Molecular weight: Translated: 40525; Mature: 40525

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDYVEIGMGREARRTYHLDSVAIVPSRRTRSSKDVDTTWHIDAYTFDIPFMSHPTDALA
CCCCEEECCCCHHHHEEECCCEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHC
TPDFVIEMDKQGGLGVINAEGLWGRHADLDAAIQEVITAYGDDELDLGSCNRATKKLQEL
CCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
HAAALDTELLVERIAQVRSSGATVAVRVSPQHCHELAPILIKAGAELLIVQGTIISAEHV
HHHHCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCEEEEEECEEEEHHHC
ETNGEPLNLKEFIGSIDVPVIAGGVNDYTTALHLMRAGAVGIIAGGGQNTNDCALGIDDS
CCCCCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHH
LATIIADVAAARRDYLDETGGRYVHVIADGQIFTSGDAVKAIACGADAVILGEPLARAAE
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEECCCCEEEECCHHHHHHH
AGGKGLYWPSAAAHPRFPRGVVGTAGVMPKTEQVSLEVLLHGPSTNVFGEENFVGGLKRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHH
MAKCGYTDLKSFQKVDLTVQF
HHHCCCHHHHCCEEEEEEEEC
>Mature Secondary Structure
MRDYVEIGMGREARRTYHLDSVAIVPSRRTRSSKDVDTTWHIDAYTFDIPFMSHPTDALA
CCCCEEECCCCHHHHEEECCCEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHC
TPDFVIEMDKQGGLGVINAEGLWGRHADLDAAIQEVITAYGDDELDLGSCNRATKKLQEL
CCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
HAAALDTELLVERIAQVRSSGATVAVRVSPQHCHELAPILIKAGAELLIVQGTIISAEHV
HHHHCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCEEEEEECEEEEHHHC
ETNGEPLNLKEFIGSIDVPVIAGGVNDYTTALHLMRAGAVGIIAGGGQNTNDCALGIDDS
CCCCCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHH
LATIIADVAAARRDYLDETGGRYVHVIADGQIFTSGDAVKAIACGADAVILGEPLARAAE
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCEEEEECCCCEEEECCHHHHHHH
AGGKGLYWPSAAAHPRFPRGVVGTAGVMPKTEQVSLEVLLHGPSTNVFGEENFVGGLKRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHH
MAKCGYTDLKSFQKVDLTVQF
HHHCCCHHHHCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: inosine 5'-phosphate; NAD+; H2O

Specific reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA