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The map label for this gene is ftsW [H]

Identifier: 38232692

GI number: 38232692

Start: 48687

End: 50036

Strand: Reverse

Name: ftsW [H]

Synonym: DIP0056

Alternate gene names: 38232692

Gene position: 50036-48687 (Counterclockwise)

Preceding gene: 38232693

Following gene: 38232691

Centisome position: 2.01

GC content: 58.89

Gene sequence:

>1350_bases
ATGACCTCCCTACGACGCATTACCGCACGCCCCGTGGAATTCGGGCTACTCGTGATGGCAACCCTGCTCATCGCAGTCAC
CCTAATTAACCTCAACATGGCCCAAGGGCTTTCGGTCACCTCCGAAACACTCTGGGTGATTGGCGGCTTCATCGGCGTGT
TCACCATCGCCCACCTCGCGCTATGTTTTACCGCCCCGCATGCCGACCAAGTCATGCTGCCGGTAGCCAGCGTGCTCAAC
GGGCTAGGGCTGGTCATGGTGTACCGCATCGACCTCGCACGTGACACCGCCCTTGCTAGTCGCCAGGTGATCTGGACCCT
TGTGGGTATCCTCCTCATGATCGCCGTCTTGGTGTTTATTCGCGACCACCGGATGTTGTCGCGCTACTCCTATGTGCTGG
GCTTGCTTGGTCTGATCTTGCTCGCACTGCCCATGGTGTGGCCCACAAAGATGAATGCCGACGCCAACATTTGGATCTCC
ATCGGACCGTTCTCCGTGCAGCCAGGTGAGTTTTCCAAGATCTTGCTGCTGATTTTCTTCGCGCAGCTTTTGGTCAACAA
ACGCGCCCTATTTAACGTGGCCGGCTACCGATTCCTCGGGCTCGAGTTCCCGCGCCTCCGCGACCTAGGCCCCATCCTCG
GCGTGTGGGCCTTCGCCATTTTGGTCATGGCCGGCGAGAACGACTTCGGCCCCGCACTGCTGCTGTTTAGCACCGTGCTC
GGCATGCTGTACCTAGCCACCAACCGCGTATCGTGGCTGATCATTGGTGCAGCACTTGTGGCCGTTGGTGGTACCGCGCT
GTACCAGATCTCCAGCAAAATCCAGTCGCGCGTAACCAACTTTATTAACCCACTGGATAACTTCAACGGCACGGGTTACC
AGCTCTCGCAGTCACTCTTCGGGCTGTCTTCTGGTGGCGTGGCCGGCGCTGGGCTTGGTTTAGGCCACCCAGAGCTGATC
CCAGTTGCTGAGTCCGACTTCATCCTCGCCGCCGTGGGCGAGGAACTCGGCTTTATTGGACTTGCTGCCGTGCTGGTTCT
CTTTGCCATCTTTATCACCCGCGGTCTGCGCACTGCGCTGCGGGCACGTGATTCCTACGGCAAGCTCATGGCTGCTGGCC
TCTCGCTGACCTTGGCCATCCAGGTCTTTGTGGTCACCGCTGGAATTACCGCCCTCATGCCGATGACGGGTCTGACCACG
CCGTTTATGTCTCAAGGCGGGTCTAGTTTGATGGCTAACTACATTCTTCTCGGACTGATCCTTAGGATCTCCCACTCCAC
ACAAGCCGCCGCCAACGACGTGGTGTCTATGGACGAGCAGGCGGCACGAGGTCAGGAGGCCCACCGATGA

Upstream 100 bases:

>100_bases
GAGTGCAGCCCCTACGACTACAAAGGCGGCGTCGCCAAGCAGTACCGGCTCCCCCGATGATCTCTCCACACCTGGCGAAA
CCTGCAGGGAGGTCAAATAA

Downstream 100 bases:

>100_bases
ACCGATCTATCCGATTCACCAGCGTGTTCGCGCTGCTGCTGATCCTGATTTTGTTGGTCAACTTGACGATCATTCAGGGT
TTTAGTCAGGAAAAATACGC

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTSLRRITARPVEFGLLVMATLLIAVTLINLNMAQGLSVTSETLWVIGGFIGVFTIAHLALCFTAPHADQVMLPVASVLN
GLGLVMVYRIDLARDTALASRQVIWTLVGILLMIAVLVFIRDHRMLSRYSYVLGLLGLILLALPMVWPTKMNADANIWIS
IGPFSVQPGEFSKILLLIFFAQLLVNKRALFNVAGYRFLGLEFPRLRDLGPILGVWAFAILVMAGENDFGPALLLFSTVL
GMLYLATNRVSWLIIGAALVAVGGTALYQISSKIQSRVTNFINPLDNFNGTGYQLSQSLFGLSSGGVAGAGLGLGHPELI
PVAESDFILAAVGEELGFIGLAAVLVLFAIFITRGLRTALRARDSYGKLMAAGLSLTLAIQVFVVTAGITALMPMTGLTT
PFMSQGGSSLMANYILLGLILRISHSTQAAANDVVSMDEQAARGQEAHR

Sequences:

>Translated_449_residues
MTSLRRITARPVEFGLLVMATLLIAVTLINLNMAQGLSVTSETLWVIGGFIGVFTIAHLALCFTAPHADQVMLPVASVLN
GLGLVMVYRIDLARDTALASRQVIWTLVGILLMIAVLVFIRDHRMLSRYSYVLGLLGLILLALPMVWPTKMNADANIWIS
IGPFSVQPGEFSKILLLIFFAQLLVNKRALFNVAGYRFLGLEFPRLRDLGPILGVWAFAILVMAGENDFGPALLLFSTVL
GMLYLATNRVSWLIIGAALVAVGGTALYQISSKIQSRVTNFINPLDNFNGTGYQLSQSLFGLSSGGVAGAGLGLGHPELI
PVAESDFILAAVGEELGFIGLAAVLVLFAIFITRGLRTALRARDSYGKLMAAGLSLTLAIQVFVVTAGITALMPMTGLTT
PFMSQGGSSLMANYILLGLILRISHSTQAAANDVVSMDEQAARGQEAHR
>Mature_448_residues
TSLRRITARPVEFGLLVMATLLIAVTLINLNMAQGLSVTSETLWVIGGFIGVFTIAHLALCFTAPHADQVMLPVASVLNG
LGLVMVYRIDLARDTALASRQVIWTLVGILLMIAVLVFIRDHRMLSRYSYVLGLLGLILLALPMVWPTKMNADANIWISI
GPFSVQPGEFSKILLLIFFAQLLVNKRALFNVAGYRFLGLEFPRLRDLGPILGVWAFAILVMAGENDFGPALLLFSTVLG
MLYLATNRVSWLIIGAALVAVGGTALYQISSKIQSRVTNFINPLDNFNGTGYQLSQSLFGLSSGGVAGAGLGLGHPELIP
VAESDFILAAVGEELGFIGLAAVLVLFAIFITRGLRTALRARDSYGKLMAAGLSLTLAIQVFVVTAGITALMPMTGLTTP
FMSQGGSSLMANYILLGLILRISHSTQAAANDVVSMDEQAARGQEAHR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=332, Percent_Identity=31.0240963855422, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786853, Length=293, Percent_Identity=29.0102389078498, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 48109; Mature: 47978

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLRRITARPVEFGLLVMATLLIAVTLINLNMAQGLSVTSETLWVIGGFIGVFTIAHLA
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LCFTAPHADQVMLPVASVLNGLGLVMVYRIDLARDTALASRQVIWTLVGILLMIAVLVFI
HHHCCCCCCHHHHHHHHHHHHHHEEHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDHRMLSRYSYVLGLLGLILLALPMVWPTKMNADANIWISIGPFSVQPGEFSKILLLIFF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
AQLLVNKRALFNVAGYRFLGLEFPRLRDLGPILGVWAFAILVMAGENDFGPALLLFSTVL
HHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
GMLYLATNRVSWLIIGAALVAVGGTALYQISSKIQSRVTNFINPLDNFNGTGYQLSQSLF
HHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GLSSGGVAGAGLGLGHPELIPVAESDFILAAVGEELGFIGLAAVLVLFAIFITRGLRTAL
CCCCCCCCCCCCCCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARDSYGKLMAAGLSLTLAIQVFVVTAGITALMPMTGLTTPFMSQGGSSLMANYILLGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHH
LRISHSTQAAANDVVSMDEQAARGQEAHR
HHHCCCHHHHHHHHHHCCHHHHCCCCCCC
>Mature Secondary Structure 
TSLRRITARPVEFGLLVMATLLIAVTLINLNMAQGLSVTSETLWVIGGFIGVFTIAHLA
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LCFTAPHADQVMLPVASVLNGLGLVMVYRIDLARDTALASRQVIWTLVGILLMIAVLVFI
HHHCCCCCCHHHHHHHHHHHHHHEEHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDHRMLSRYSYVLGLLGLILLALPMVWPTKMNADANIWISIGPFSVQPGEFSKILLLIFF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
AQLLVNKRALFNVAGYRFLGLEFPRLRDLGPILGVWAFAILVMAGENDFGPALLLFSTVL
HHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
GMLYLATNRVSWLIIGAALVAVGGTALYQISSKIQSRVTNFINPLDNFNGTGYQLSQSLF
HHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GLSSGGVAGAGLGLGHPELIPVAESDFILAAVGEELGFIGLAAVLVLFAIFITRGLRTAL
CCCCCCCCCCCCCCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARDSYGKLMAAGLSLTLAIQVFVVTAGITALMPMTGLTTPFMSQGGSSLMANYILLGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHH
LRISHSTQAAANDVVSMDEQAARGQEAHR
HHHCCCHHHHHHHHHHCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]