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The map label for this gene is moeZ [H]

Identifier: 38232676

GI number: 38232676

Start: 32071

End: 33084

Strand: Direct

Name: moeZ [H]

Synonym: DIP0034

Alternate gene names: 38232676

Gene position: 32071-33084 (Clockwise)

Preceding gene: 38232675

Following gene: 38232677

Centisome position: 1.29

GC content: 58.58

Gene sequence:

>1014_bases
GTGATGCTCGACGAGCTGGAACGCCAACGCGTAGCCCGCCAACTGCGGCTACCTGGTTTTGGGATTGAGCAGCAAGAACG
GCTCAACAACGGGCGAGTGCTGGTGATCGGTGCTGGGGGACTGGGCAGTCCTGCCTTGCAGTCCCTTGCGGCGGCTGGGG
TGGGGTCGATCCGACTCGTGGATAACGACACCGTGGATGTGTCCAACATTCAACGCCAGATCCTGTTTGGTGTTGGGGAT
GTAGGGCGCTCCAAAGTTCACGTCGCCGCCGAAAGATTGCGTGCAATTCAACCCGGGATTCGTATCGACGCCCGCACCGA
ACGCCTCACCGCACACAACGCACACGAACTCGCCGAAGGCTGCGACGTGATCCTCGACGGCTCCGACACCTTTGCTACCA
AATTTCTCTGCGGCGACCTCGCCGAAATAACAGGCATACCGCTCGTCTGGGGCAGCGTACTGCAATTCGAAGGGCACATG
GGCGTATTCACCCGCGAGGTAGGGCTACGGGACCTGTTCCCCGAAGCCCCCACCCAAGGACTCAACTGTGCCGACGCAGG
CGTACTCGGCGCTACCACCGCAGTGATCGCCAACCTCATGGCCACTGAAACCATCAAAATCCTCGCCGGAATCGGAACCG
TCCAACCAGGAGCCGTCACCACCTACAATGCGTTGACCAGCACATTTCGCACATACACTGTGGGGCGTGACCCCCTTCGA
TCTGCAGCCCGCACACTTTACACGTGGACGCTACCCAACGAATACGAACTTATCGACGTCCGCGAACCCCACGAAATAGA
ACACACACCCAGCGGCGCGCACATCACCCTGCCACAATCCATGTGGAATGACACCACGGCGATCCAACATGCGCTCGACA
ACATCACCACAGACAATGTGGTCGTCGTCTGTGCCTCTGGCATAAGAAGTGCCGCATTTATCGAACAATTCGCACACCTT
AACCCACACCTCACCTTCCACAACGTCCCCAGCGGAATCAACGAACTACCATGA

Upstream 100 bases:

>100_bases
CAGGACGACTCGCGCGCGAAGCCGGGCGCATACCGCGCCGGGAGCATGCGGTGGCGTCGTCAAGCTTTGAAGGGCTCGCC
TCCTGGGCGGACGAGGTGCT

Downstream 100 bases:

>100_bases
CCCCACACATACTCACCATCGCAGGATCCGACCCCTCCGGCGGGGCCGGAATCCAAGCAGACCTCAAATCCATCATGGCA
GCCGGCGGCTACGGCATGGC

Product: thiamine biosynthesis protein ThiF

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MMLDELERQRVARQLRLPGFGIEQQERLNNGRVLVIGAGGLGSPALQSLAAAGVGSIRLVDNDTVDVSNIQRQILFGVGD
VGRSKVHVAAERLRAIQPGIRIDARTERLTAHNAHELAEGCDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHM
GVFTREVGLRDLFPEAPTQGLNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGAVTTYNALTSTFRTYTVGRDPLR
SAARTLYTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWNDTTAIQHALDNITTDNVVVVCASGIRSAAFIEQFAHL
NPHLTFHNVPSGINELP

Sequences:

>Translated_337_residues
MMLDELERQRVARQLRLPGFGIEQQERLNNGRVLVIGAGGLGSPALQSLAAAGVGSIRLVDNDTVDVSNIQRQILFGVGD
VGRSKVHVAAERLRAIQPGIRIDARTERLTAHNAHELAEGCDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHM
GVFTREVGLRDLFPEAPTQGLNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGAVTTYNALTSTFRTYTVGRDPLR
SAARTLYTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWNDTTAIQHALDNITTDNVVVVCASGIRSAAFIEQFAHL
NPHLTFHNVPSGINELP
>Mature_337_residues
MMLDELERQRVARQLRLPGFGIEQQERLNNGRVLVIGAGGLGSPALQSLAAAGVGSIRLVDNDTVDVSNIQRQILFGVGD
VGRSKVHVAAERLRAIQPGIRIDARTERLTAHNAHELAEGCDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHM
GVFTREVGLRDLFPEAPTQGLNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGAVTTYNALTSTFRTYTVGRDPLR
SAARTLYTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWNDTTAIQHALDNITTDNVVVVCASGIRSAAFIEQFAHL
NPHLTFHNVPSGINELP

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=224, Percent_Identity=41.5178571428571, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI38045944, Length=117, Percent_Identity=39.3162393162393, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38045942, Length=117, Percent_Identity=39.3162393162393, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4885649, Length=84, Percent_Identity=46.4285714285714, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787048, Length=242, Percent_Identity=38.4297520661157, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87082356, Length=237, Percent_Identity=35.0210970464135, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789177, Length=150, Percent_Identity=32.6666666666667, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17540406, Length=255, Percent_Identity=32.9411764705882, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71984476, Length=195, Percent_Identity=34.8717948717949, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193203301, Length=171, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI86565433, Length=112, Percent_Identity=37.5, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI86565431, Length=112, Percent_Identity=37.5, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=359, Percent_Identity=30.6406685236769, Blast_Score=135, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6322639, Length=97, Percent_Identity=36.0824742268041, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320598, Length=142, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582879, Length=229, Percent_Identity=39.7379912663755, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24660640, Length=142, Percent_Identity=30.2816901408451, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129973, Length=78, Percent_Identity=41.025641025641, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 36324; Mature: 36324

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLDELERQRVARQLRLPGFGIEQQERLNNGRVLVIGAGGLGSPALQSLAAAGVGSIRLV
CCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEE
DNDTVDVSNIQRQILFGVGDVGRSKVHVAAERLRAIQPGIRIDARTERLTAHNAHELAEG
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHCCHHHHHCC
CDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHMGVFTREVGLRDLFPEAPTQG
CCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCEEEHHCCHHHCCCCCCCCC
LNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGAVTTYNALTSTFRTYTVGRDPLR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHEECCCHHHH
SAARTLYTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWNDTTAIQHALDNITTDNV
HHHHEEEEEECCCCEEEEECCCCCCCCCCCCCCEEECCHHHCCHHHHHHHHHHCCCCCCE
VVVCASGIRSAAFIEQFAHLNPHLTFHNVPSGINELP
EEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MMLDELERQRVARQLRLPGFGIEQQERLNNGRVLVIGAGGLGSPALQSLAAAGVGSIRLV
CCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEE
DNDTVDVSNIQRQILFGVGDVGRSKVHVAAERLRAIQPGIRIDARTERLTAHNAHELAEG
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHCCHHHHHCC
CDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHMGVFTREVGLRDLFPEAPTQG
CCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCEEEHHCCHHHCCCCCCCCC
LNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGAVTTYNALTSTFRTYTVGRDPLR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHEECCCHHHH
SAARTLYTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWNDTTAIQHALDNITTDNV
HHHHEEEEEECCCCEEEEECCCCCCCCCCCCCCEEECCHHHCCHHHHHHHHHHCCCCCCE
VVVCASGIRSAAFIEQFAHLNPHLTFHNVPSGINELP
EEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]