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The map label for this gene is mcp4 [H]

Identifier: 37681071

GI number: 37681071

Start: 2938642

End: 2940279

Strand: Direct

Name: mcp4 [H]

Synonym: VV2887

Alternate gene names: 37681071

Gene position: 2938642-2940279 (Clockwise)

Preceding gene: 37681070

Following gene: 37681072

Centisome position: 87.6

GC content: 48.35

Gene sequence:

>1638_bases
ATGAGCATTTTTATGAAACTTAAGACACAAGCTTATTTATTATCGGGAATTATCTTAATTGCCCTACTCGCGTTAACCGC
TACTGGCCTTTGGACACTAAGGGTGGCCAGTAATCTAGATAACAAAGCACGAGTAACCGAACTCTTTCGCAGCGCTTATA
GCATCCTGACCGAGGTCGAGAAAATGGCCGTTGAAGGAAAAATGTCTGAGCCAGAAGCGAAAGCATTAGCCACTCGACTA
CTACGTAATAACATCTACAAAGACAATGAGTATGTTTACGTTGCCGATGAAAAAATGATCTTTATTGCCACTCCATTAGA
TCCACAACTTCATGGCACCAGTTTTCATGATTTTCGAGATGGTAATGGCAACAGCGTTGGCCAGTTAATCCTAGATGTGC
TTGGCCGAAAAACAGGCCAACTGGTGGAATATACTTGGACGCAAAAACTGGCCGATGGCTCGATTGAGGAAAAACTCTCA
ATCGCAGAAAGAACCCCACACTGGGGTTGGGTTGTCGGTACGGGTATCGGCTTCAATGAAGTGAATGCTCGCTTTTGGTC
TACCGCCCAATGGCAGTTAGTCCTTTGTCTTGTGATTGCAGGCACGATTTTGGGTGGCTTGATTGTTTCCATCAATAAAA
TGCTGAATCTGTTGGGTGGCGAGCCAAATGATGTGCGCAACGCAGTACAAGACGTGGCAAAAGGTCGCATCCAAACCAGT
TTCGACAATAAAGCGCCACAAGGCAGTATTTACCAGGCCGTGCAAGAGATGAGCCTCTCCTTAGCCGAGATGATCAGCAA
CCTAGAACGTTCAATGCACGCACTGCGTGACGAACTGGCGTCCGTTGAAAGCCGTAGCGATACCATTTCCAGCCTCACTG
CGACACAGCAACAGTCGACCGCGATGATAGCAACAGCGATGACAGAAATGGCTTCTTCTGCAAATCACGTCGCCGATTCC
GCCAGTGATACTGCCAACAATACGGATGAAGCCGACAAACAGAGTAAACATACACAGGTGCTGATTCACAATACCGTCAG
CAACATCCAGGGATTGGCAAGCCAGTTAGGCACCGCCAGCCAAGCGGTGGCAGACCTCGACAAAGACGTGAACAACATTG
TAAAAGTGCTCGATGTGATCGGCGATATTGCGGAGCAGACTAACCTGCTCGCGCTCAATGCAGCGATCGAAGCGGCGCGA
GCGGGCGAGCAAGGAAGAGGTTTTGCCGTCGTCGCGGACGAAGTACGTAACCTTGCAGGAAGAACCCAATCCAGCACTAA
AGAGATCCAGTTGATGATCAATAACTTGCAACAAGGTTCTCGCAACGCCATCCAAACCATGGAAATCTGTGCGGAGACCA
GCCAAAGCACCGCTGTTGAATCGCAAACAGCTTCAGAAGCGTTGCAACAGATTGTTCAGGCATTGGAGTCCATCAGTACC
ATGAGTCAACAAATTGCGACCGCCGCCGCAGAACAAACACAAGTGAGTGATGATATTGCACAGCGTATCAACATGATTGA
AGACAGCGGCAATCAGCTTACCACCGTCGTCACAAAGAGTCACAACAGCACGCGCAGCTTGGCTACCTTAGCGAACCAAC
TCGAAAACTGGGTCAATAAGTTTTCTGTAAAGCATTAA

Upstream 100 bases:

>100_bases
TTGACGCTAAGCAGCTACTTGTTTCACTCGTGCTACATTAATATTTCATTTCAATTAAACGGACAAACCAAGCATTTGCC
GTGTTCATTGTGACTACAAT

Downstream 100 bases:

>100_bases
ACTAAACTTGTTTTCTAACTAAGCACGCCTTATCGCGTGCTTTTTTATTGCTGGAATCGCTGTTCATCCAATTAAATCTG
ATAAACAAATGTCGCTTAGA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MSIFMKLKTQAYLLSGIILIALLALTATGLWTLRVASNLDNKARVTELFRSAYSILTEVEKMAVEGKMSEPEAKALATRL
LRNNIYKDNEYVYVADEKMIFIATPLDPQLHGTSFHDFRDGNGNSVGQLILDVLGRKTGQLVEYTWTQKLADGSIEEKLS
IAERTPHWGWVVGTGIGFNEVNARFWSTAQWQLVLCLVIAGTILGGLIVSINKMLNLLGGEPNDVRNAVQDVAKGRIQTS
FDNKAPQGSIYQAVQEMSLSLAEMISNLERSMHALRDELASVESRSDTISSLTATQQQSTAMIATAMTEMASSANHVADS
ASDTANNTDEADKQSKHTQVLIHNTVSNIQGLASQLGTASQAVADLDKDVNNIVKVLDVIGDIAEQTNLLALNAAIEAAR
AGEQGRGFAVVADEVRNLAGRTQSSTKEIQLMINNLQQGSRNAIQTMEICAETSQSTAVESQTASEALQQIVQALESIST
MSQQIATAAAEQTQVSDDIAQRINMIEDSGNQLTTVVTKSHNSTRSLATLANQLENWVNKFSVKH

Sequences:

>Translated_545_residues
MSIFMKLKTQAYLLSGIILIALLALTATGLWTLRVASNLDNKARVTELFRSAYSILTEVEKMAVEGKMSEPEAKALATRL
LRNNIYKDNEYVYVADEKMIFIATPLDPQLHGTSFHDFRDGNGNSVGQLILDVLGRKTGQLVEYTWTQKLADGSIEEKLS
IAERTPHWGWVVGTGIGFNEVNARFWSTAQWQLVLCLVIAGTILGGLIVSINKMLNLLGGEPNDVRNAVQDVAKGRIQTS
FDNKAPQGSIYQAVQEMSLSLAEMISNLERSMHALRDELASVESRSDTISSLTATQQQSTAMIATAMTEMASSANHVADS
ASDTANNTDEADKQSKHTQVLIHNTVSNIQGLASQLGTASQAVADLDKDVNNIVKVLDVIGDIAEQTNLLALNAAIEAAR
AGEQGRGFAVVADEVRNLAGRTQSSTKEIQLMINNLQQGSRNAIQTMEICAETSQSTAVESQTASEALQQIVQALESIST
MSQQIATAAAEQTQVSDDIAQRINMIEDSGNQLTTVVTKSHNSTRSLATLANQLENWVNKFSVKH
>Mature_544_residues
SIFMKLKTQAYLLSGIILIALLALTATGLWTLRVASNLDNKARVTELFRSAYSILTEVEKMAVEGKMSEPEAKALATRLL
RNNIYKDNEYVYVADEKMIFIATPLDPQLHGTSFHDFRDGNGNSVGQLILDVLGRKTGQLVEYTWTQKLADGSIEEKLSI
AERTPHWGWVVGTGIGFNEVNARFWSTAQWQLVLCLVIAGTILGGLIVSINKMLNLLGGEPNDVRNAVQDVAKGRIQTSF
DNKAPQGSIYQAVQEMSLSLAEMISNLERSMHALRDELASVESRSDTISSLTATQQQSTAMIATAMTEMASSANHVADSA
SDTANNTDEADKQSKHTQVLIHNTVSNIQGLASQLGTASQAVADLDKDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARA
GEQGRGFAVVADEVRNLAGRTQSSTKEIQLMINNLQQGSRNAIQTMEICAETSQSTAVESQTASEALQQIVQALESISTM
SQQIATAAAEQTQVSDDIAQRINMIEDSGNQLTTVVTKSHNSTRSLATLANQLENWVNKFSVKH

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=274, Percent_Identity=29.5620437956204, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788194, Length=303, Percent_Identity=29.3729372937294, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI2367378, Length=406, Percent_Identity=26.3546798029557, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1787690, Length=299, Percent_Identity=28.7625418060201, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=31.7073170731707, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59127; Mature: 58996

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFMKLKTQAYLLSGIILIALLALTATGLWTLRVASNLDNKARVTELFRSAYSILTEVE
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHHHHHHHHHHH
KMAVEGKMSEPEAKALATRLLRNNIYKDNEYVYVADEKMIFIATPLDPQLHGTSFHDFRD
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCC
GNGNSVGQLILDVLGRKTGQLVEYTWTQKLADGSIEEKLSIAERTPHWGWVVGTGIGFNE
CCCCHHHHHHHHHHCCCCCCCEEHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHH
VNARFWSTAQWQLVLCLVIAGTILGGLIVSINKMLNLLGGEPNDVRNAVQDVAKGRIQTS
HCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
FDNKAPQGSIYQAVQEMSLSLAEMISNLERSMHALRDELASVESRSDTISSLTATQQQST
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIATAMTEMASSANHVADSASDTANNTDEADKQSKHTQVLIHNTVSNIQGLASQLGTAS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHCHHH
QAVADLDKDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHC
RTQSSTKEIQLMINNLQQGSRNAIQTMEICAETSQSTAVESQTASEALQQIVQALESIST
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSQQIATAAAEQTQVSDDIAQRINMIEDSGNQLTTVVTKSHNSTRSLATLANQLENWVNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
FSVKH
HCCCC
>Mature Secondary Structure 
SIFMKLKTQAYLLSGIILIALLALTATGLWTLRVASNLDNKARVTELFRSAYSILTEVE
CEEEEHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHCCCCHHHHHHHHHHHHHHHHHHH
KMAVEGKMSEPEAKALATRLLRNNIYKDNEYVYVADEKMIFIATPLDPQLHGTSFHDFRD
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCC
GNGNSVGQLILDVLGRKTGQLVEYTWTQKLADGSIEEKLSIAERTPHWGWVVGTGIGFNE
CCCCHHHHHHHHHHCCCCCCCEEHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHH
VNARFWSTAQWQLVLCLVIAGTILGGLIVSINKMLNLLGGEPNDVRNAVQDVAKGRIQTS
HCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
FDNKAPQGSIYQAVQEMSLSLAEMISNLERSMHALRDELASVESRSDTISSLTATQQQST
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIATAMTEMASSANHVADSASDTANNTDEADKQSKHTQVLIHNTVSNIQGLASQLGTAS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHCHHH
QAVADLDKDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHC
RTQSSTKEIQLMINNLQQGSRNAIQTMEICAETSQSTAVESQTASEALQQIVQALESIST
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSQQIATAAAEQTQVSDDIAQRINMIEDSGNQLTTVVTKSHNSTRSLATLANQLENWVNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
FSVKH
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]