Click here to switch to the map view.

The map label for this gene is astE [H]

Identifier: 37679663

GI number: 37679663

Start: 1516360

End: 1517388

Strand: Direct

Name: astE [H]

Synonym: VV1479

Alternate gene names: 37679663

Gene position: 1516360-1517388 (Clockwise)

Preceding gene: 37679662

Following gene: 37679664

Centisome position: 45.2

GC content: 46.45

Gene sequence:

>1029_bases
ATGACGAATTCTCTCTTTCGCCAATCGTTTTTGTCAGACACCCTAAATATGCAGCAATCTGTCGAGGCGAAAGCGACGAC
GTTAAGCAATGGGGTAAGATTGCAGCTGCATCAGCGTGGTGTGTTAGAAGTCATTCCGGCAAACAACAGCGCGGAAACAA
AAAATATCATTTTATCGTCAGGGATCCACGGTGATGAAACCGCACCGATGGAACTGATTGACAAGATTGTTCACGATATC
GAAACGGGCTTTCAAGATGTGCAAGCGCGTTGTTTATTTATCATCGCTCATCCAGAAGCGACCAATGCGCACACGCGTTT
TATTGAAGAAAACCTCAACCGTCTGTTTGATGAAAAAGAGCATCAGCCAAGCAAAGAGTTGGTGATTGCCGATCAACTGA
AGTTATTGGTGAAAGCGTTTTTCGATAATACGCCCGTAGAAAGCCGTTGGCACTTAGATTTGCATTGCGCGATACGAGCG
TCGAAGCACTATTCGTTCGCGATCAGTCCGAAAACGCGCCATCCGACACGTTCAAAAGCGTTGGTCGATTTTGTCAACCA
CAGCCACGTCGAAGCGTTGCTGCTCTCTAATTCACCATCCAGCACGTTTAGCTGGTTCAGTGCAGAATACTATTCTGCTC
AAGCACTGACGATGGAGTTAGGCCGAGTCGCTCGCATTGGTGAAAATGATTTAAGCAGATTTACCGCACTGGATTTAACC
ATGCGTGATTTGATCGCGGAAGTGACTCCAGAGCATTTGCCTAAGCCGGCTATTACTTATCGTGTTAGCCGCACCATTGT
TCGTTTGCATCAAGACTTCGATTTCAGATTTGACGATCAAGTGGAAAACTTTACCTCGTTTATGCACGGTGAAGTGTTTG
GCCACGATGGTGATAAGCCGTTGATGGCGAAGAATGACAATGAAGCGATTGTGTTCCCTAACCGTAACGTGGCAATTGGT
CAACGCGCCGCGCTAATGGTTTGTGAGATCAAAGCCCGCTTTGAAGACGATCAACTGGTTTACGATTAA

Upstream 100 bases:

>100_bases
TGCGGTGAAAACTTTGATTTCTCATGATAAGTGAGATCCTAGCAACATAAATGTTGTGTACATTTTATTAACATACCGCC
GTGCAATTAAGGAGTAACGC

Downstream 100 bases:

>100_bases
GCTCTTTTGCGCTCAGGCTGCTTAAGAGCACCAAGAGAGCGAGTTTAATGGTTTATTTCTGAAAGGCTTAACGTTAGAGT
TAAGCCTTTTGTTTAGCGAG

Product: succinylglutamate desuccinylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTNSLFRQSFLSDTLNMQQSVEAKATTLSNGVRLQLHQRGVLEVIPANNSAETKNIILSSGIHGDETAPMELIDKIVHDI
ETGFQDVQARCLFIIAHPEATNAHTRFIEENLNRLFDEKEHQPSKELVIADQLKLLVKAFFDNTPVESRWHLDLHCAIRA
SKHYSFAISPKTRHPTRSKALVDFVNHSHVEALLLSNSPSSTFSWFSAEYYSAQALTMELGRVARIGENDLSRFTALDLT
MRDLIAEVTPEHLPKPAITYRVSRTIVRLHQDFDFRFDDQVENFTSFMHGEVFGHDGDKPLMAKNDNEAIVFPNRNVAIG
QRAALMVCEIKARFEDDQLVYD

Sequences:

>Translated_342_residues
MTNSLFRQSFLSDTLNMQQSVEAKATTLSNGVRLQLHQRGVLEVIPANNSAETKNIILSSGIHGDETAPMELIDKIVHDI
ETGFQDVQARCLFIIAHPEATNAHTRFIEENLNRLFDEKEHQPSKELVIADQLKLLVKAFFDNTPVESRWHLDLHCAIRA
SKHYSFAISPKTRHPTRSKALVDFVNHSHVEALLLSNSPSSTFSWFSAEYYSAQALTMELGRVARIGENDLSRFTALDLT
MRDLIAEVTPEHLPKPAITYRVSRTIVRLHQDFDFRFDDQVENFTSFMHGEVFGHDGDKPLMAKNDNEAIVFPNRNVAIG
QRAALMVCEIKARFEDDQLVYD
>Mature_341_residues
TNSLFRQSFLSDTLNMQQSVEAKATTLSNGVRLQLHQRGVLEVIPANNSAETKNIILSSGIHGDETAPMELIDKIVHDIE
TGFQDVQARCLFIIAHPEATNAHTRFIEENLNRLFDEKEHQPSKELVIADQLKLLVKAFFDNTPVESRWHLDLHCAIRAS
KHYSFAISPKTRHPTRSKALVDFVNHSHVEALLLSNSPSSTFSWFSAEYYSAQALTMELGRVARIGENDLSRFTALDLTM
RDLIAEVTPEHLPKPAITYRVSRTIVRLHQDFDFRFDDQVENFTSFMHGEVFGHDGDKPLMAKNDNEAIVFPNRNVAIGQ
RAALMVCEIKARFEDDQLVYD

Specific function: Transforms N(2)-succinylglutamate into succinate and glutamate [H]

COG id: COG2988

COG function: function code E; Succinylglutamate desuccinylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788040, Length=324, Percent_Identity=32.7160493827161, Blast_Score=177, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007036
- InterPro:   IPR016681 [H]

Pfam domain/function: PF04952 AstE_AspA [H]

EC number: =3.5.1.96 [H]

Molecular weight: Translated: 38847; Mature: 38716

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSLFRQSFLSDTLNMQQSVEAKATTLSNGVRLQLHQRGVLEVIPANNSAETKNIILSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCEEEEEC
GIHGDETAPMELIDKIVHDIETGFQDVQARCLFIIAHPEATNAHTRFIEENLNRLFDEKE
CCCCCCCCHHHHHHHHHHHHHHCHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
HQPSKELVIADQLKLLVKAFFDNTPVESRWHLDLHCAIRASKHYSFAISPKTRHPTRSKA
CCCCHHEEHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCCHHHH
LVDFVNHSHVEALLLSNSPSSTFSWFSAEYYSAQALTMELGRVARIGENDLSRFTALDLT
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MRDLIAEVTPEHLPKPAITYRVSRTIVRLHQDFDFRFDDQVENFTSFMHGEVFGHDGDKP
HHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEECCCCCCC
LMAKNDNEAIVFPNRNVAIGQRAALMVCEIKARFEDDQLVYD
CEECCCCCEEEECCCCEECCCCCEEEEEEEECCCCCCCEECC
>Mature Secondary Structure 
TNSLFRQSFLSDTLNMQQSVEAKATTLSNGVRLQLHQRGVLEVIPANNSAETKNIILSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCEEEEEC
GIHGDETAPMELIDKIVHDIETGFQDVQARCLFIIAHPEATNAHTRFIEENLNRLFDEKE
CCCCCCCCHHHHHHHHHHHHHHCHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
HQPSKELVIADQLKLLVKAFFDNTPVESRWHLDLHCAIRASKHYSFAISPKTRHPTRSKA
CCCCHHEEHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCCHHHH
LVDFVNHSHVEALLLSNSPSSTFSWFSAEYYSAQALTMELGRVARIGENDLSRFTALDLT
HHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MRDLIAEVTPEHLPKPAITYRVSRTIVRLHQDFDFRFDDQVENFTSFMHGEVFGHDGDKP
HHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEECCCCCCC
LMAKNDNEAIVFPNRNVAIGQRAALMVCEIKARFEDDQLVYD
CEECCCCCEEEECCCCEECCCCCEEEEEEEECCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA