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The map label for this gene is dhaT [H]

Identifier: 37679624

GI number: 37679624

Start: 1472662

End: 1473909

Strand: Direct

Name: dhaT [H]

Synonym: VV1440

Alternate gene names: 37679624

Gene position: 1472662-1473909 (Clockwise)

Preceding gene: 37679621

Following gene: 37679630

Centisome position: 43.9

GC content: 48.32

Gene sequence:

>1248_bases
ATGTTCCAGTTTATGACCGCAACACGAATTATTTTTGGCGAAGGCGCGTTACAGTCCTCACTCTCTATCCTCAGTCAGTT
TGGTTACAGTGCTTTATTGGTCACAGGAAAAGATCTTGCGAGGGCGATGCCCATTATTGGCTATTTCAAATCACAGAATA
TTCGTTATCAGCATGTCGCGATCAGTGGTGAACCTAATATTACTATGGTGGAGGAAACGGCCGTCATAGGTAGAAAGTTT
AAGCCAGACATGGTTGTCGCTATTGGTGGGGGGAGTGTTATTGATATGGGTAAAGCGCTGGCTGCGATCATCCCCAATCA
AGGCGATGTGTACGACTACGTCGAAGTGGTGGGCAGAAATGTGCCATTAAAAACACAACCTATACACTTTATCGCCATTC
CGACGACGGCCAGCACTGGATCGGAAGTGACGCGAAATGCGGTATTAAAATCGGGCCAGGATAAAGTGAAAGTGAGTCTG
CGCAGTCCGGATATGCTTGCCGATGTGGCGATTGTCGACCCGACACTCACCTATGGTACTGATGCCTATACATCCGGCCG
TGGCGCGATGGATGCCTTTACCCATTTAATGGAAGCCTATGTCTGTGGTGAGCCGAATCCGCTGACGGATATGATATGTG
AAGAAGGGCTACGACGATTAAGTCACTCTATCATTCCGGGTTGCTTACAAGATGATTACAAAGCGCGCTCAGACTTGGCA
TTTTCCGCAATGCTCGGTGGAATGGCGATCACCAATGCTAAATTAGGTGCGGCTCATGGTTTAGCTTCAGCCCTTGGTGG
AAAGCTGGATGCACCACACAGTGTGATCACTGCGCAGCTCGCGCCACATGTGATGAACGAAAATATTATGGCGGCGCGAG
AAGCGGGCAGAGCCGACGTGCTCACTCGTTATAAGTCTTTGGCTCGATTGGTCACAAAAAATGGTGACGCTAGTGAGTTA
GAAGGCGTGGAATGGGTTAAAGGTGTCTTGGATAAGTTGCAGCTTCCTGAGCTGAGTCAGTTTGGTGTCTGTTCGACATC
GTTTGATGCGGTCGCGGAAGATGCCTTGCGCTCAGTTGCGATTAAAGGAAACCCTTTGCCACTGACTAAAGCGAGGTTGA
TCTATATATTGGAGCAAGTTTGTCAGTGCCGTTTGCGTTCTGAGCAAACCCAGCAAGAAGCCACTGGATGCGCACAGTTT
ATCGAGAGTGAAGATTACAATCTCGAAATGGGGAATGAGATAAAATAA

Upstream 100 bases:

>100_bases
CAAATTGCACTTGGTCAATTTTTTTACGTACAAAGATAGGCAAAGTGAAACGACACCTAAGATTTTACTCGTAGTTTCTA
ATATTAAGAGGCAATGCAGT

Downstream 100 bases:

>100_bases
CGGAGCCGTCAGGCTCCGTGATTCGTATTGAGAGTATCGCTTTCAACCAGAATTGGCTTGCGATTAGAAATGCGTAAGTT
TGTCGTATCGGCTGTCTTTC

Product: alcohol dehydrogenase, class IV

Products: NA

Alternate protein names: 1,3-propanediol oxidoreductase; 3-hydroxypropionaldehyde reductase [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MFQFMTATRIIFGEGALQSSLSILSQFGYSALLVTGKDLARAMPIIGYFKSQNIRYQHVAISGEPNITMVEETAVIGRKF
KPDMVVAIGGGSVIDMGKALAAIIPNQGDVYDYVEVVGRNVPLKTQPIHFIAIPTTASTGSEVTRNAVLKSGQDKVKVSL
RSPDMLADVAIVDPTLTYGTDAYTSGRGAMDAFTHLMEAYVCGEPNPLTDMICEEGLRRLSHSIIPGCLQDDYKARSDLA
FSAMLGGMAITNAKLGAAHGLASALGGKLDAPHSVITAQLAPHVMNENIMAAREAGRADVLTRYKSLARLVTKNGDASEL
EGVEWVKGVLDKLQLPELSQFGVCSTSFDAVAEDALRSVAIKGNPLPLTKARLIYILEQVCQCRLRSEQTQQEATGCAQF
IESEDYNLEMGNEIK

Sequences:

>Translated_415_residues
MFQFMTATRIIFGEGALQSSLSILSQFGYSALLVTGKDLARAMPIIGYFKSQNIRYQHVAISGEPNITMVEETAVIGRKF
KPDMVVAIGGGSVIDMGKALAAIIPNQGDVYDYVEVVGRNVPLKTQPIHFIAIPTTASTGSEVTRNAVLKSGQDKVKVSL
RSPDMLADVAIVDPTLTYGTDAYTSGRGAMDAFTHLMEAYVCGEPNPLTDMICEEGLRRLSHSIIPGCLQDDYKARSDLA
FSAMLGGMAITNAKLGAAHGLASALGGKLDAPHSVITAQLAPHVMNENIMAAREAGRADVLTRYKSLARLVTKNGDASEL
EGVEWVKGVLDKLQLPELSQFGVCSTSFDAVAEDALRSVAIKGNPLPLTKARLIYILEQVCQCRLRSEQTQQEATGCAQF
IESEDYNLEMGNEIK
>Mature_415_residues
MFQFMTATRIIFGEGALQSSLSILSQFGYSALLVTGKDLARAMPIIGYFKSQNIRYQHVAISGEPNITMVEETAVIGRKF
KPDMVVAIGGGSVIDMGKALAAIIPNQGDVYDYVEVVGRNVPLKTQPIHFIAIPTTASTGSEVTRNAVLKSGQDKVKVSL
RSPDMLADVAIVDPTLTYGTDAYTSGRGAMDAFTHLMEAYVCGEPNPLTDMICEEGLRRLSHSIIPGCLQDDYKARSDLA
FSAMLGGMAITNAKLGAAHGLASALGGKLDAPHSVITAQLAPHVMNENIMAAREAGRADVLTRYKSLARLVTKNGDASEL
EGVEWVKGVLDKLQLPELSQFGVCSTSFDAVAEDALRSVAIKGNPLPLTKARLIYILEQVCQCRLRSEQTQQEATGCAQF
IESEDYNLEMGNEIK

Specific function: Most active with substrates containing two primary alcohol groups separated by one or two carbon atoms. In the physiological direction, 3-hydroxypropionaldehyde is the preferred substrate [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI48994951, Length=387, Percent_Identity=28.1653746770026, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI87082107, Length=309, Percent_Identity=31.0679611650485, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789163, Length=378, Percent_Identity=28.8359788359788, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787493, Length=405, Percent_Identity=27.1604938271605, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789386, Length=378, Percent_Identity=24.3386243386243, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=287, Percent_Identity=25.4355400696864, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321181, Length=381, Percent_Identity=32.2834645669291, Blast_Score=159, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.202 [H]

Molecular weight: Translated: 44669; Mature: 44669

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQFMTATRIIFGEGALQSSLSILSQFGYSALLVTGKDLARAMPIIGYFKSQNIRYQHVA
CCCHHHHHEEEECCCHHHHHHHHHHHCCCEEEEEECHHHHHHCCHHHEECCCCEEEEEEE
ISGEPNITMVEETAVIGRKFKPDMVVAIGGGSVIDMGKALAAIIPNQGDVYDYVEVVGRN
ECCCCCEEEEEHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
VPLKTQPIHFIAIPTTASTGSEVTRNAVLKSGQDKVKVSLRSPDMLADVAIVDPTLTYGT
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHEEEEEECCCCCCCC
DAYTSGRGAMDAFTHLMEAYVCGEPNPLTDMICEEGLRRLSHSIIPGCLQDDYKARSDLA
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FSAMLGGMAITNAKLGAAHGLASALGGKLDAPHSVITAQLAPHVMNENIMAAREAGRADV
HHHHHCCHHEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCHHHH
LTRYKSLARLVTKNGDASELEGVEWVKGVLDKLQLPELSQFGVCSTSFDAVAEDALRSVA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEE
IKGNPLPLTKARLIYILEQVCQCRLRSEQTQQEATGCAQFIESEDYNLEMGNEIK
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MFQFMTATRIIFGEGALQSSLSILSQFGYSALLVTGKDLARAMPIIGYFKSQNIRYQHVA
CCCHHHHHEEEECCCHHHHHHHHHHHCCCEEEEEECHHHHHHCCHHHEECCCCEEEEEEE
ISGEPNITMVEETAVIGRKFKPDMVVAIGGGSVIDMGKALAAIIPNQGDVYDYVEVVGRN
ECCCCCEEEEEHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
VPLKTQPIHFIAIPTTASTGSEVTRNAVLKSGQDKVKVSLRSPDMLADVAIVDPTLTYGT
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHEEEEEECCCCCCCC
DAYTSGRGAMDAFTHLMEAYVCGEPNPLTDMICEEGLRRLSHSIIPGCLQDDYKARSDLA
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FSAMLGGMAITNAKLGAAHGLASALGGKLDAPHSVITAQLAPHVMNENIMAAREAGRADV
HHHHHCCHHEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCHHHH
LTRYKSLARLVTKNGDASELEGVEWVKGVLDKLQLPELSQFGVCSTSFDAVAEDALRSVA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEE
IKGNPLPLTKARLIYILEQVCQCRLRSEQTQQEATGCAQFIESEDYNLEMGNEIK
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721705 [H]