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The map label for this gene is glnS [H]

Identifier: 37679197

GI number: 37679197

Start: 1012283

End: 1013953

Strand: Direct

Name: glnS [H]

Synonym: VV1013

Alternate gene names: 37679197

Gene position: 1012283-1013953 (Clockwise)

Preceding gene: 37679196

Following gene: 37679199

Centisome position: 30.18

GC content: 45.78

Gene sequence:

>1671_bases
ATGAGTGAAGCTGATGCTCGTCCATCAAACTTTATTCGTCAGATCATTGATAAAGATCTGGCGGATGGCAAACACACGAG
TGTGCATACACGATTCCCACCGGAGCCAAACGGCTACCTACACATCGGCCATGCAAAATCGATCTGTTTGAACTTTGGTA
TTGCTCAGGACTATCAGGGTAAGTGTAATCTTCGTTTCGACGATACCAACCCTGAGAAAGAAGACATCGAATACGTTGAG
TCGATCAAAAATGATGTGAGCTGGTTAGGCTTTGAATGGGATGATGAGATCTGTTACTCATCGAACTATTTCGACAAGCT
TTACGAGTATGCAGTGGAACTGATTAACAAAGGCTTAGCGTACGTTGATGAGCTAAGTCCAGAGCAGATCCGTGAATACC
GTGGTACGTTGACTGCGCCAGGTAAGCCTAGCCCTTATCGTGATCGTTCTGCAGAAGAAAACCTTGCGCTGTTTGAAAAA
ATGCGCGATGGCGGTTTTGAAGAAGGTAAAGCGTGTCTTCGTGCGAAGATTGACATGGCATCGTCGTTCATGGTTATGCG
CGATCCTGTTCTTTACCGCGTGCGTTTTGCGTCTCACCACCAGACAGGTGACAAATGGTGCATTTACCCAATGTACGACT
TTACGCACTGTATTTCAGATGCGTTAGAAGGCATTACGCACTCAATTTGTACTCTTGAGTTTATGGACAACCGTCGTTTG
TACGACTGGGTTCTCGACAACATCACCATTGATTGCCGTCCTCATCAATACGAGTTCAGCCGTCTGAACCTTGAATACAC
AGTAATGTCTAAGCGTAAGCTCAACCAGTTGGTGACTGAGAAGTTGGTTAATGGCTGGGATGACCCACGTATGCCGACGA
TCTCTGGTTTACGCCGTCGCGGTTTCACACCTGCGTCAATTCGCGAGTTTTGTAAGCGTATCGGTGTGACGAAGCAAGAA
AACATGATCGAGTTTAGTTCATTGGAATCTTGCATCCGTGATGATTTGAATGAAAATGCTCCTCGTGCAATGGCGGTGTT
GGATCCTGTTAAGCTAGTGATTGAAAACTTCCCTGCAGGCGAAGTAGAAAATCTGACGGTTGCTAACCATCCAAATAAGC
CAGAAATGGGTGAGCGTGAAGTTCCGTTTAGCCGTGAAATTTGGATCGAGCGTGAAGATTTCCGCGAAGAAGCAAACAAG
AAGTACAAACGTTTGGTTCTTGGCAGTGAAGTACGTCTGCGTGGCGCGTACGTGATTAAAGCTGAGCGTGTTGAGAAAGA
CGACGAAGGTAATATCACGACTATCTTCTGTACTTACGATTCAGAGACTTTGGGTGTTAACCCTGCGGATGGCCGTAAAG
TACGTGGTGTAATTCACTGGGTATCGGCGGATAAAGGTGTTCCTGCTGAAATTCGTCTATACGATCGTCTATTCACGGTA
CCAAATCCAGCAGCGGCAGATGACTTTGCTTCAACCATCAATCCGGAATCTTTAACGGTGATGAATGGCTTTGTTGAGCC
AAGCTTAGTGGAAGCAGAAGCTGAAAAAGGCTATCAGTTTGAGCGTATGGGTTACTTCTGTGCGGATTCTAAAGACTCCT
CTAAAGAGCATTTAGTTTTCAACCGTACTGTAGGTCTACGTGATACTTGGGCGAAGATTGAAGCGAAATAA

Upstream 100 bases:

>100_bases
GAATTGTGGATCATTAACGACAGTTTGCTCTGAAGTCGTGTTGACGTTTCAGAGCTAAGTTTTCTCTGAACAATACTAAA
ACAAACTTGAGGTGCTTTAG

Downstream 100 bases:

>100_bases
GCGCTATTAAGCTAAGAAAAACCCAACTCATTGAGTTGGGTTTTTTATGGGCGCAACAAAAAGCCAGCAATATGCTGGCT
TTTAAGGTCTATCGAGCGTC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MSEADARPSNFIRQIIDKDLADGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGKCNLRFDDTNPEKEDIEYVE
SIKNDVSWLGFEWDDEICYSSNYFDKLYEYAVELINKGLAYVDELSPEQIREYRGTLTAPGKPSPYRDRSAEENLALFEK
MRDGGFEEGKACLRAKIDMASSFMVMRDPVLYRVRFASHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRL
YDWVLDNITIDCRPHQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTISGLRRRGFTPASIREFCKRIGVTKQE
NMIEFSSLESCIRDDLNENAPRAMAVLDPVKLVIENFPAGEVENLTVANHPNKPEMGEREVPFSREIWIEREDFREEANK
KYKRLVLGSEVRLRGAYVIKAERVEKDDEGNITTIFCTYDSETLGVNPADGRKVRGVIHWVSADKGVPAEIRLYDRLFTV
PNPAAADDFASTINPESLTVMNGFVEPSLVEAEAEKGYQFERMGYFCADSKDSSKEHLVFNRTVGLRDTWAKIEAK

Sequences:

>Translated_556_residues
MSEADARPSNFIRQIIDKDLADGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGKCNLRFDDTNPEKEDIEYVE
SIKNDVSWLGFEWDDEICYSSNYFDKLYEYAVELINKGLAYVDELSPEQIREYRGTLTAPGKPSPYRDRSAEENLALFEK
MRDGGFEEGKACLRAKIDMASSFMVMRDPVLYRVRFASHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRL
YDWVLDNITIDCRPHQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTISGLRRRGFTPASIREFCKRIGVTKQE
NMIEFSSLESCIRDDLNENAPRAMAVLDPVKLVIENFPAGEVENLTVANHPNKPEMGEREVPFSREIWIEREDFREEANK
KYKRLVLGSEVRLRGAYVIKAERVEKDDEGNITTIFCTYDSETLGVNPADGRKVRGVIHWVSADKGVPAEIRLYDRLFTV
PNPAAADDFASTINPESLTVMNGFVEPSLVEAEAEKGYQFERMGYFCADSKDSSKEHLVFNRTVGLRDTWAKIEAK
>Mature_555_residues
SEADARPSNFIRQIIDKDLADGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGKCNLRFDDTNPEKEDIEYVES
IKNDVSWLGFEWDDEICYSSNYFDKLYEYAVELINKGLAYVDELSPEQIREYRGTLTAPGKPSPYRDRSAEENLALFEKM
RDGGFEEGKACLRAKIDMASSFMVMRDPVLYRVRFASHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRLY
DWVLDNITIDCRPHQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTISGLRRRGFTPASIREFCKRIGVTKQEN
MIEFSSLESCIRDDLNENAPRAMAVLDPVKLVIENFPAGEVENLTVANHPNKPEMGEREVPFSREIWIEREDFREEANKK
YKRLVLGSEVRLRGAYVIKAERVEKDDEGNITTIFCTYDSETLGVNPADGRKVRGVIHWVSADKGVPAEIRLYDRLFTVP
NPAAADDFASTINPESLTVMNGFVEPSLVEAEAEKGYQFERMGYFCADSKDSSKEHLVFNRTVGLRDTWAKIEAK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=533, Percent_Identity=47.0919324577861, Blast_Score=465, Evalue=1e-131,
Organism=Homo sapiens, GI62241042, Length=536, Percent_Identity=33.5820895522388, Blast_Score=288, Evalue=9e-78,
Organism=Escherichia coli, GI1786895, Length=553, Percent_Identity=81.7359855334539, Blast_Score=957, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=122, Percent_Identity=31.9672131147541, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17543332, Length=533, Percent_Identity=44.0900562851782, Blast_Score=435, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17511007, Length=526, Percent_Identity=33.0798479087452, Blast_Score=259, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6324742, Length=566, Percent_Identity=43.1095406360424, Blast_Score=411, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321192, Length=527, Percent_Identity=35.8633776091082, Blast_Score=317, Evalue=2e-87,
Organism=Drosophila melanogaster, GI17864488, Length=532, Percent_Identity=44.5488721804511, Blast_Score=457, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24649466, Length=515, Percent_Identity=33.7864077669903, Blast_Score=275, Evalue=4e-74,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63929; Mature: 63797

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEADARPSNFIRQIIDKDLADGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQG
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHEEHEECCCCCCCCC
KCNLRFDDTNPEKEDIEYVESIKNDVSWLGFEWDDEICYSSNYFDKLYEYAVELINKGLA
CEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
YVDELSPEQIREYRGTLTAPGKPSPYRDRSAEENLALFEKMRDGGFEEGKACLRAKIDMA
HHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SSFMVMRDPVLYRVRFASHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRL
HCCHHHCCCEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCCH
YDWVLDNITIDCRPHQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTISGLRRR
HHHHHCCEEEECCCCCEEHHHEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHC
GFTPASIREFCKRIGVTKQENMIEFSSLESCIRDDLNENAPRAMAVLDPVKLVIENFPAG
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
EVENLTVANHPNKPEMGEREVPFSREIWIEREDFREEANKKYKRLVLGSEVRLRGAYVIK
CCCCEEECCCCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
AERVEKDDEGNITTIFCTYDSETLGVNPADGRKVRGVIHWVSADKGVPAEIRLYDRLFTV
EHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEHHCCC
PNPAAADDFASTINPESLTVMNGFVEPSLVEAEAEKGYQFERMGYFCADSKDSSKEHLVF
CCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEHHCCEEEECCCCCCCCEEEE
NRTVGLRDTWAKIEAK
EECCCCCCCCCEEECC
>Mature Secondary Structure 
SEADARPSNFIRQIIDKDLADGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQG
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCHHEEHEECCCCCCCCC
KCNLRFDDTNPEKEDIEYVESIKNDVSWLGFEWDDEICYSSNYFDKLYEYAVELINKGLA
CEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
YVDELSPEQIREYRGTLTAPGKPSPYRDRSAEENLALFEKMRDGGFEEGKACLRAKIDMA
HHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SSFMVMRDPVLYRVRFASHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRL
HCCHHHCCCEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCCH
YDWVLDNITIDCRPHQYEFSRLNLEYTVMSKRKLNQLVTEKLVNGWDDPRMPTISGLRRR
HHHHHCCEEEECCCCCEEHHHEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHC
GFTPASIREFCKRIGVTKQENMIEFSSLESCIRDDLNENAPRAMAVLDPVKLVIENFPAG
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
EVENLTVANHPNKPEMGEREVPFSREIWIEREDFREEANKKYKRLVLGSEVRLRGAYVIK
CCCCEEECCCCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
AERVEKDDEGNITTIFCTYDSETLGVNPADGRKVRGVIHWVSADKGVPAEIRLYDRLFTV
EHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEECCCCCCCEEEEEEHHCCC
PNPAAADDFASTINPESLTVMNGFVEPSLVEAEAEKGYQFERMGYFCADSKDSSKEHLVF
CCCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEHHCCEEEECCCCCCCCEEEE
NRTVGLRDTWAKIEAK
EECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA