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The map label for this gene is wzb [C]

Identifier: 37678523

GI number: 37678523

Start: 345845

End: 346285

Strand: Direct

Name: wzb [C]

Synonym: VV0339

Alternate gene names: 37678523

Gene position: 345845-346285 (Clockwise)

Preceding gene: 37678522

Following gene: 37678524

Centisome position: 10.31

GC content: 45.58

Gene sequence:

>441_bases
ATGTTTAACAAAATCTTAGTCGTTTGTGTCGGTAACATTTGCCGCTCTCCAACTGGTGAGCGTGTGCTACAAAAACTACT
TCCGAATAAAACCGTTGCTTCTGCCGGTATTGCAGCAGAGAAAAGCCGTTTAATTGGTAAGCCAGCCGATGCAATGGCGA
TAGAAGTGGCAAAAGAGAATGGTGTTGATGTAGAAAACCATCAATCACAGCAACTTACCTCTGCGCTGTGTAGCCAATAT
GATCTGATCCTCGTAATGGAAAAAGGCCATATGGAAGCACTAACACAAATCGCTCCTGAAGCGCGCGGAAAAACCATGCT
ATTCGGCCAATGGATTGGACAAAAAGATATCCCCGATCCGTATCGCCAAAGCAAAGAAGCCTTCGCGCACGCTTATCAGT
TAATTGACGAAGCCGCACAAGCCTGGGCAAAGAAATTGTAG

Upstream 100 bases:

>100_bases
GGACTAGGAAGAGCAAAAACCTAGAAAACTTCTCTTCCCTAGAATACTAGCTACCTTCTTTACCTAGCAACCTTCTCTTC
CCTAGCAACCTGAGGAAAAC

Downstream 100 bases:

>100_bases
AAGAGCAGGGACGAGGAAGAAAGAGCAGGAGCGAGGTTACTAGGAACTAGGAAAAGACTAGTAACTAAGAAAGAACAGGG
ACGAGATTACTAGGGACTAG

Product: cytoplasmic phosphatase

Products: NA

Alternate protein names: ORF5 [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKENGVDVENHQSQQLTSALCSQY
DLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDPYRQSKEAFAHAYQLIDEAAQAWAKKL

Sequences:

>Translated_146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKENGVDVENHQSQQLTSALCSQY
DLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDPYRQSKEAFAHAYQLIDEAAQAWAKKL
>Mature_146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKENGVDVENHQSQQLTSALCSQY
DLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDPYRQSKEAFAHAYQLIDEAAQAWAKKL

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=149, Percent_Identity=29.5302013422819, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI6005988, Length=149, Percent_Identity=27.5167785234899, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788375, Length=146, Percent_Identity=54.7945205479452, Blast_Score=171, Evalue=2e-44,
Organism=Escherichia coli, GI87081812, Length=145, Percent_Identity=55.8620689655172, Blast_Score=164, Evalue=3e-42,
Organism=Drosophila melanogaster, GI78706766, Length=152, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI78706768, Length=152, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16036; Mature: 16036

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKEN
CCCHHHHEEHHHHHCCCCHHHHHHHHCCCCHHHHHCHHHHHHHHCCCCCHHHHEEECCCC
GVDVENHQSQQLTSALCSQYDLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDP
CCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCH
YRQSKEAFAHAYQLIDEAAQAWAKKL
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFNKILVVCVGNICRSPTGERVLQKLLPNKTVASAGIAAEKSRLIGKPADAMAIEVAKEN
CCCHHHHEEHHHHHCCCCHHHHHHHHCCCCHHHHHCHHHHHHHHCCCCCHHHHEEECCCC
GVDVENHQSQQLTSALCSQYDLILVMEKGHMEALTQIAPEARGKTMLFGQWIGQKDIPDP
CCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCH
YRQSKEAFAHAYQLIDEAAQAWAKKL
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896702 [H]