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The map label for this gene is mcp4 [H]

Identifier: 37678468

GI number: 37678468

Start: 294941

End: 296662

Strand: Direct

Name: mcp4 [H]

Synonym: VV0284

Alternate gene names: 37678468

Gene position: 294941-296662 (Clockwise)

Preceding gene: 37678464

Following gene: 37678469

Centisome position: 8.79

GC content: 48.32

Gene sequence:

>1722_bases
TTGCGATACCTCTTAAAAATTAAAACAATCATATGGATAGCGACGGAACTTGTTATGAAGAGTCGGAACAAATTATTGCT
GCTAACGTTAATCCCATTAGTGCTGCTGACAGCGATGGTGACAGCGGTTTTCTATTTTAACAGTGTAAAAAGCTTAGACG
TTGAACTCAGCGAATATCGAAATGAGCTGATTGAAACGCGCAAAAGCGAGTTAAAAGCCTATTTGATGATGGGCGTCACC
GCCATTAAACCGCTGTATGACGCGGATGTGAATGGCAACAATCAACAACAAGCCAAACAGATTTTGAAAGCAATGCGCTT
TGAAAGTGATGGTTACTTTTTTGCTTATGATTCTAAAGGCGTCAACACGCTGCACGCGATAAAGCCAGAGTTGGAAGGTA
AAAATCTTTACGGCATGAAAGATGACAATGGTGTCGCGGTGATAGCGGGGTTGATTGACGCTTCACAAAAAGGCGATGGC
TTTCTTTATTTCTCTTGGCACAAGCCGACCATCAATGCGCAAGCGCCTAAATTGGGTTATGCGGAATATCTACCAAAATG
GGATTGGGTACTCGGCACAGGGATCTACATTGACGATATCGACACGCAAGTGGCAGAGCATCGTGTACAAAGTATTGCCA
GTTTGAATGAGCATACCTTATCGGCGATTGGATTCACGTTGGTGGGGTTATTGATTGCGTGTGGTGTGATCAGCGTGATT
GTTTCTCGGGCGATTTTGCCGCTGCAACATATCGCGGCCTCATTGCAAGATGTAGCGGCAGGCGGTGGCGATTTAACCGC
TCGTTTGAGTGTCGAAAGCCAAGATGAAGTGGGGGAAGTGGCCAAAGCCTTCAACCAGTTTATGGACAAATTGCATCCTT
TGATGGTCGATATTCGCAGCTCGGCGCAAACAGTGCAAAGCGCTGCCACTGGGCTGGATCAACAAACCTCGTTAGCCAGT
AACCAAATGCAAACGCACTGTTTGGAGACGGATAAAGTAGTCACCGCCGTGACGGAAATGAGCGCCACGGCGAGAGAAGT
CGCCAACAATACCCATGCCACGGCGCAGGCCATTGATTCTGCCAATGCGCAGATCTCAGAAGCGCAAGTCGAAGTGAATC
ACGCGATAGAAGGGATTGGTAAATTGGTCGACGAAGTGAACATCACCTCAGACGCCATTTCTCAGCTTAGCCAACAGACC
GATCAAATCACCAAAGTGTTGCAAGTGATAGGCGAAATTGCTGAGCAAACGAACTTACTGGCACTGAATGCCGCCATTGA
AGCGGCGCGTGCGGGAGAGCAAGGCCGCGGATTTGCCGTGGTTGCCGATGAAGTTCGTTCATTAGCGAGTCGCACACAAA
ACAGCACGCTGGAAATTGGCGATATGCTTAAGCAGTTGCAAAACGGGGTGGCCAGAGCGGTCACCACCATGTCTGCCAGC
CAAGAGCGTGGCGAGCAAACGGCGCTTGAGTCAGTGCAAATCAAAGAATCACTTGCTGGCATCCAGTCGGCGGTGGAAAT
GATCCGTGATATGGGCATTCAAACGGCATCCGCCGCTGAACAACAGAGCGCGGTCGCTGAGGACATCAATCAAAACCTGG
TCACCATTCAGCAAATCGTTAATGAGATTAATAACAACTTACAAGAGTCGGAAACCATTAGCACACGCTTGAGTGTGTCT
GGCCAAGAAATGCATGATTTGGTCGGTCACTTTAAGCTCTGA

Upstream 100 bases:

>100_bases
AAGGCGGTTTTACTTCTCTAATTGAAGACAAACTCGACAAAGAGATCAGAGAAACAGCACGTTGCTCACAGACATTGACT
AAATAGACACCAGATAATGT

Downstream 100 bases:

>100_bases
TAAAACGCTCAGTTACATTATCTTCTTCTATTAATAACGAACCAGCATCGTCATACTAGACTTTGCTGGTTTTCTCGTTG
CAATAGGCGCATCTAAGATG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MRYLLKIKTIIWIATELVMKSRNKLLLLTLIPLVLLTAMVTAVFYFNSVKSLDVELSEYRNELIETRKSELKAYLMMGVT
AIKPLYDADVNGNNQQQAKQILKAMRFESDGYFFAYDSKGVNTLHAIKPELEGKNLYGMKDDNGVAVIAGLIDASQKGDG
FLYFSWHKPTINAQAPKLGYAEYLPKWDWVLGTGIYIDDIDTQVAEHRVQSIASLNEHTLSAIGFTLVGLLIACGVISVI
VSRAILPLQHIAASLQDVAAGGGDLTARLSVESQDEVGEVAKAFNQFMDKLHPLMVDIRSSAQTVQSAATGLDQQTSLAS
NQMQTHCLETDKVVTAVTEMSATAREVANNTHATAQAIDSANAQISEAQVEVNHAIEGIGKLVDEVNITSDAISQLSQQT
DQITKVLQVIGEIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQNSTLEIGDMLKQLQNGVARAVTTMSAS
QERGEQTALESVQIKESLAGIQSAVEMIRDMGIQTASAAEQQSAVAEDINQNLVTIQQIVNEINNNLQESETISTRLSVS
GQEMHDLVGHFKL

Sequences:

>Translated_573_residues
MRYLLKIKTIIWIATELVMKSRNKLLLLTLIPLVLLTAMVTAVFYFNSVKSLDVELSEYRNELIETRKSELKAYLMMGVT
AIKPLYDADVNGNNQQQAKQILKAMRFESDGYFFAYDSKGVNTLHAIKPELEGKNLYGMKDDNGVAVIAGLIDASQKGDG
FLYFSWHKPTINAQAPKLGYAEYLPKWDWVLGTGIYIDDIDTQVAEHRVQSIASLNEHTLSAIGFTLVGLLIACGVISVI
VSRAILPLQHIAASLQDVAAGGGDLTARLSVESQDEVGEVAKAFNQFMDKLHPLMVDIRSSAQTVQSAATGLDQQTSLAS
NQMQTHCLETDKVVTAVTEMSATAREVANNTHATAQAIDSANAQISEAQVEVNHAIEGIGKLVDEVNITSDAISQLSQQT
DQITKVLQVIGEIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQNSTLEIGDMLKQLQNGVARAVTTMSAS
QERGEQTALESVQIKESLAGIQSAVEMIRDMGIQTASAAEQQSAVAEDINQNLVTIQQIVNEINNNLQESETISTRLSVS
GQEMHDLVGHFKL
>Mature_573_residues
MRYLLKIKTIIWIATELVMKSRNKLLLLTLIPLVLLTAMVTAVFYFNSVKSLDVELSEYRNELIETRKSELKAYLMMGVT
AIKPLYDADVNGNNQQQAKQILKAMRFESDGYFFAYDSKGVNTLHAIKPELEGKNLYGMKDDNGVAVIAGLIDASQKGDG
FLYFSWHKPTINAQAPKLGYAEYLPKWDWVLGTGIYIDDIDTQVAEHRVQSIASLNEHTLSAIGFTLVGLLIACGVISVI
VSRAILPLQHIAASLQDVAAGGGDLTARLSVESQDEVGEVAKAFNQFMDKLHPLMVDIRSSAQTVQSAATGLDQQTSLAS
NQMQTHCLETDKVVTAVTEMSATAREVANNTHATAQAIDSANAQISEAQVEVNHAIEGIGKLVDEVNITSDAISQLSQQT
DQITKVLQVIGEIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQNSTLEIGDMLKQLQNGVARAVTTMSAS
QERGEQTALESVQIKESLAGIQSAVEMIRDMGIQTASAAEQQSAVAEDINQNLVTIQQIVNEINNNLQESETISTRLSVS
GQEMHDLVGHFKL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=30.5555555555556, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787690, Length=246, Percent_Identity=32.9268292682927, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788195, Length=518, Percent_Identity=25.6756756756757, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1789453, Length=241, Percent_Identity=33.6099585062241, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788194, Length=338, Percent_Identity=25.7396449704142, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62248; Mature: 62248

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLLKIKTIIWIATELVMKSRNKLLLLTLIPLVLLTAMVTAVFYFNSVKSLDVELSEYR
CCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NELIETRKSELKAYLMMGVTAIKPLYDADVNGNNQQQAKQILKAMRFESDGYFFAYDSKG
HHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCC
VNTLHAIKPELEGKNLYGMKDDNGVAVIAGLIDASQKGDGFLYFSWHKPTINAQAPKLGY
CCHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCEEEEEEEECCCCCCCCCCCCH
AEYLPKWDWVLGTGIYIDDIDTQVAEHRVQSIASLNEHTLSAIGFTLVGLLIACGVISVI
HHHCCCCCHHEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRAILPLQHIAASLQDVAAGGGDLTARLSVESQDEVGEVAKAFNQFMDKLHPLMVDIRS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAQTVQSAATGLDQQTSLASNQMQTHCLETDKVVTAVTEMSATAREVANNTHATAQAIDS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ANAQISEAQVEVNHAIEGIGKLVDEVNITSDAISQLSQQTDQITKVLQVIGEIAEQTNLL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ALNAAIEAARAGEQGRGFAVVADEVRSLASRTQNSTLEIGDMLKQLQNGVARAVTTMSAS
EHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QERGEQTALESVQIKESLAGIQSAVEMIRDMGIQTASAAEQQSAVAEDINQNLVTIQQIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEINNNLQESETISTRLSVSGQEMHDLVGHFKL
HHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRYLLKIKTIIWIATELVMKSRNKLLLLTLIPLVLLTAMVTAVFYFNSVKSLDVELSEYR
CCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NELIETRKSELKAYLMMGVTAIKPLYDADVNGNNQQQAKQILKAMRFESDGYFFAYDSKG
HHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCC
VNTLHAIKPELEGKNLYGMKDDNGVAVIAGLIDASQKGDGFLYFSWHKPTINAQAPKLGY
CCHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCEEEEEEEECCCCCCCCCCCCH
AEYLPKWDWVLGTGIYIDDIDTQVAEHRVQSIASLNEHTLSAIGFTLVGLLIACGVISVI
HHHCCCCCHHEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRAILPLQHIAASLQDVAAGGGDLTARLSVESQDEVGEVAKAFNQFMDKLHPLMVDIRS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAQTVQSAATGLDQQTSLASNQMQTHCLETDKVVTAVTEMSATAREVANNTHATAQAIDS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ANAQISEAQVEVNHAIEGIGKLVDEVNITSDAISQLSQQTDQITKVLQVIGEIAEQTNLL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ALNAAIEAARAGEQGRGFAVVADEVRSLASRTQNSTLEIGDMLKQLQNGVARAVTTMSAS
EHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QERGEQTALESVQIKESLAGIQSAVEMIRDMGIQTASAAEQQSAVAEDINQNLVTIQQIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NEINNNLQESETISTRLSVSGQEMHDLVGHFKL
HHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]