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The map label for this gene is epsI [H]

Identifier: 37678403

GI number: 37678403

Start: 230969

End: 231403

Strand: Direct

Name: epsI [H]

Synonym: VV0219

Alternate gene names: 37678403

Gene position: 230969-231403 (Clockwise)

Preceding gene: 37678402

Following gene: 37678404

Centisome position: 6.89

GC content: 53.1

Gene sequence:

>435_bases
ATGGTTGGCGAGTACGAGCCAAAGACACAGGGCAGATTATTCTGCTGGCCCCCGGTGAAGAAGAGCAAGACGATGGTTAA
ACGACGCAAATACGCAGGCATGACCTTGCTTGAGGTGCTGGTGGCGTTGGCGATATTTGCCACTGCGGCGATGAGCGTGA
TTCGTGCGGTTAGCCAGCACATCAACACCGTCGGTTATTTGGAGCAGAAGATGTTTGCTGCCATGGTGGCCGACAATCAA
ATGGCGATGGTGATGCTCAACCCCAAAAACCTAAAAGCCAGCAATGGCGAAGAAGAGTTGGCGGGGCAAACTTGGTATTG
GAAAGTCGCACCCGTAGCCACGACCCAGCCGCTGCTGAAAGCGTTTGATGTGAGTGTGGCAGCCGAAAAGCAGGCCAGCC
CAATAATTACGGTGAGAAGCTATGTGGCGAAATAA

Upstream 100 bases:

>100_bases
GAGAAAAAACAGCGACCGCCGCAGATTTTCATTTTATCCAGCGGAGAATTGACGCCGTTTTCATTGTCTTTTTATCCCGA
CGATCAGGACGCGACCGAAA

Downstream 100 bases:

>100_bases
AACGTGTCGAAAGAGAAACACGCGCCAACGTGGTTTTACCCTCATCGAAGTGTTGGTGTCGATTGCCATTTTTGCCACCT
TAAGTGTGGCCGCATATCAG

Product: type II secretory pathway, pseudopilin EpsI

Products: NA

Alternate protein names: Cholera toxin secretion protein epsI [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MVGEYEPKTQGRLFCWPPVKKSKTMVKRRKYAGMTLLEVLVALAIFATAAMSVIRAVSQHINTVGYLEQKMFAAMVADNQ
MAMVMLNPKNLKASNGEEELAGQTWYWKVAPVATTQPLLKAFDVSVAAEKQASPIITVRSYVAK

Sequences:

>Translated_144_residues
MVGEYEPKTQGRLFCWPPVKKSKTMVKRRKYAGMTLLEVLVALAIFATAAMSVIRAVSQHINTVGYLEQKMFAAMVADNQ
MAMVMLNPKNLKASNGEEELAGQTWYWKVAPVATTQPLLKAFDVSVAAEKQASPIITVRSYVAK
>Mature_144_residues
MVGEYEPKTQGRLFCWPPVKKSKTMVKRRKYAGMTLLEVLVALAIFATAAMSVIRAVSQHINTVGYLEQKMFAAMVADNQ
MAMVMLNPKNLKASNGEEELAGQTWYWKVAPVATTQPLLKAFDVSVAAEKQASPIITVRSYVAK

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG2165

COG function: function code NU; Type II secretory pathway, pseudopilin PulG

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010052
- InterPro:   IPR012902
- InterPro:   IPR001120
- InterPro:   IPR003413 [H]

Pfam domain/function: PF02501 GSPII_IJ; PF07963 N_methyl [H]

EC number: NA

Molecular weight: Translated: 15940; Mature: 15940

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGEYEPKTQGRLFCWPPVKKSKTMVKRRKYAGMTLLEVLVALAIFATAAMSVIRAVSQH
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
INTVGYLEQKMFAAMVADNQMAMVMLNPKNLKASNGEEELAGQTWYWKVAPVATTQPLLK
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHH
AFDVSVAAEKQASPIITVRSYVAK
HHHCHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MVGEYEPKTQGRLFCWPPVKKSKTMVKRRKYAGMTLLEVLVALAIFATAAMSVIRAVSQH
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
INTVGYLEQKMFAAMVADNQMAMVMLNPKNLKASNGEEELAGQTWYWKVAPVATTQPLLK
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHH
AFDVSVAAEKQASPIITVRSYVAK
HHHCHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]